Clinical trials: Body Weight Management
Type 2 Diabetes Mellitus (T2DM), Atrial Fibrillation (AF)
Strict Weight Management Based on GLP-1 RA for Ablation Outcomes in Overweight or Obese Patients with T2DM and AF
Objective To compare, in patients with Type 2 Diabetes Mellitus (T2DM) and Atrial Fibrillation (AF) undergoing radiofrequency ablation (RFA), whether strict weight management and glycemic control based on Glucagon-like Peptide-1…
- Trial name
- NCT06660134
- Testing
- Glucagon-like peptide-1 receptor agonists (GLP 1 RA)
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Shanghai Chest Hospital
Tobacco Use Disorder
Bupropion and Weight Control for Smoking Cessation - 1
The purpose of this study is to determine whether the addition of bupropion (Zyban) to cognitive behavioral therapy (CBT) will enhance longer-term tobacco abstinence in women.
- Trial name
- NCT00006170
- Testing
- Bupropion, weight concerns intervention, smoking cessation intervention
- Where
- United States
- Volunteers
- 349 people
- Sponsor
- University of Pittsburgh
Atrial Fibrillation, Obesity and Obesity-related Medical Conditions
Metabolic Surgery for Atrial Fibrillation Elimination
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. It is estimated that between 3 and 6 million Americans are currently living with AF, while 12 million people in the United States will have AF in 2030.
- Trial name
- METSAFE (NCT07027969)
- Testing
- Roux-en-Y Gastric Bypass or Sleeve Gastrectomy, Anti-Obesity Medication (AOM) treatment
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ali Aminian
Sleep Apnea, Obstructive
Effect of Liraglutide vs CPAP on Cardiometabolic Outcomes in Obstructive Sleep Apnea
This is an explorative, proof-of-concept study exploring the potential therapeutic role of a Liraglutide-based weight loss regimen versus standard CPAP or the combination of both on metabolic parameters, blood pressure…
- Trial name
- NCT04186494
- Testing
- Liraglutide (Saxenda) 6Mg/Ml Inj Pen 3Ml, Continuous positive airway pressure treatment, Liraglutide and CPAP
- Where
- Ireland
- Volunteers
- 30 people
- Sponsor
- St Vincent's University Hospital, Ireland
Obesity
A Study to Learn How Different Amounts of the Study Medicine Danuglipron Are Taken up Into the Blood in Otherwise Healthy Adults With Overweight or Obesity
The purpose of this study is to learn the following about the study medicine, danuglipron, after multiple days of dosing in healthy adults who are overweight or obese: how the study medicine, danuglipron, is taken up into the…
- Trial name
- NCT06568731
- Testing
- Danuglipron
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy Diet, Mental Health Wellness
Online Social Support Program for Physical and Mental Health of Filipino Migrant Domestic Workers in Hong Kong
The goal of this study is to test the effect of informational and emotional social support (via nutrition education, mental health support, and/or baking classes) through two different communication modalities (online vs.
- Trial name
- NCT05660837
- Testing
- T1: Mixed mode social support group, T2: Online mode social support group
- Where
- Hong Kong
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hong Kong University of Science and Technology
Obesity & Overweight, Diabetes (DM)
Determination of Resistance Training Status for Patients on Glucagon-Like Peptide-1 Receptor Agonists
This study examines how adults who take a GLP-1 receptor agonist medication (such as semaglutide [Ozempic, Wegovy, Rybelsus], liraglutide [Saxenda, Victoza], or tirzepatide [Mounjaro, Zepbound]) perform resistance (strength)…
- Trial name
- NCT07702461
- Testing
- Glucagon-Like Peptide-1 Agonist (GLP-1)
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Ohio State University
Typ 2 Diabetes, Obesity
Multicentric Approval Study Trans-Duodenal Barrier for Typ 2 Diabetes With Obesity
Approval study Trans-Duodenal Barrier The goal of this clinical trial is to determin the safety and performance of the newly developed Trans-Duodenal Barrier in adult Tryp 2 diabetic and obese patients.
- Conditions
- Typ 2 Diabetes, Obesity, Obesity Type 2 Diabetes Mellitus, MASH
- Trial name
- LuST (NCT07417683)
- Testing
- endoscopic implant
- Where
- 8 sites in Germany
- Volunteers
- 126 people
- Sponsor
- Trans-Duodenal Concepts GmbH
Overweight and Obesity
Lifestyle Interventions in Overweight and Obese Postpartum Women
The current study aims to investigate the effects of a chosen technology-based exercise or healthy eating intervention that combines individual and group-based support, on weight loss and other health-related parameters in…
- Trial name
- NCT03826394
- Testing
- Exercise Intervention, Dietary Intervention
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- Nottingham Trent University
Obesity
Evaluation of Maridebart Cafraglutide in Adult Participants Without Type 2 Diabetes Mellitus Who Have Obesity or Are Overweight
The primary objective of this study is to demonstrate that maridebart cafraglutide is superior to placebo for percent change in body weight.
- Trial name
- MARITIME-1 (NCT06858839)
- Testing
- Maridebart Cafraglutide
- Where
- 243 sites in United States, Argentina and 15 more
- Volunteers
- 3,853 people
- Sponsor
- Amgen
Dietary Behavior; Metabolic Health; Obesity; Lifestyle Modification; Metabolic Syndrome Risk
Agentic AI Personalized Dietary Management Study
This randomized controlled trial aims to evaluate the effectiveness of an Agentic AI-based personalized dietary management algorithm among adults undergoing health screening.
- Trial name
- AIDiet (NCT07638241)
- Testing
- Static AI-based personalized dietary goal setting, Adaptive AI-based personalized dietary management
- Where
- South Korea
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Chronic Weight Management
A Study to Evaluate the Efficacy, Safety, and Tolerability in Participants With Obesity or Overweight With Weight-Related Comorbidities
This randomized, double-blind, placebo-controlled phase IIa study is designed to evaluate the efficacy, safety, and tolerability of ASC30 Tablets and ASC30 Tablets A1.
- Trial name
- NCT07002905
- Where
- 6 sites in United States
- Volunteers
- 125 people
- Sponsor
- Ascletis Pharma (China) Co., Limited
Diabetes Mellitus, Type II
GOLO Open-Label Pilot 1
The objective of this open-label pilot study is to evaluate the effect of the commercially available GOLO for Life (GFL) weight management program on body weight in a type 2 diabetic patient population after approximately 3…
- Trial name
- NCT03478202
- Testing
- GOLO RELEASE
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Golo
Hemodialysis, Interdialytic Weight Gain
This Study Evaluates the Impact of the Sodium Management Tool (SMT) on Hemodialysis Patient Outcomes Compared to Standard Care
Title of the Study: Sodium Management Tool in Hemodialysis Patients Brief Summary: The goal of this clinical trial is to learn whether the Sodium Management Tool (SMT) can improve patients clnical outcomes.
- Conditions
- Hemodialysis, Interdialytic Weight Gain, Intradialytic Hypotension
- Trial name
- SOMADIA (NCT06896786)
- Testing
- dialysis assisted with the sodium management tool
- Where
- Switzerland
- Volunteers
- 36 people
- Sponsor
- Luzerner Kantonsspital
Weight Management
GV101 in Healthy Obese Participants
The purpose of this trial is to evaluate the efficacy and safety of GV101 for weight loss over a range of doses in participants with obesity.
- Trial name
- NCT06979505
- Testing
- GV101
- Where
- 20 sites in United States, Israel
- Volunteers
- 131 people
- Sponsor
- Graviton Bioscience Corporation
Breast Neoplasm Female
Effect of Mindful Eating on Weight Management in Breast Cancer Survivors
This pilot study examined changes in anthropometric measures as a result of and feasibility/ acceptability of a mindful eating intervention for overweight and obese postmenopausal breast cancer survivors.
- Trial name
- NCT03972540
- Testing
- Mindful eating intervention
- Volunteers
- 13 people
- Sponsor
- University of Georgia
Diabetes Mellitus, Type 2
DiaMester Pilot RCT: E-health Lifestyle Program for Type 2 Diabetes
This registration covers a pilot for a 3-armed parallel-group randomized controlled trial (RCT) that will evaluate the efficacy of DiaMester, a Norwegian e-health programme designed to improve self-management and induce…
- Trial name
- DiaMester (NCT07361640)
- Testing
- e-health lifestyle program, Low calorie diet
- Where
- Norway
- Volunteers
- 99 people
- Sponsor
- Oslo University Hospital
Weight Gain
A Study on Induced Weight Gain During Atypical Antipsychotic Treatment and Its Management With Psychoeducational Programme
Olanzapine is an atypical antipsychotic agent indicated for the treatment of schizophrenia and moderate to severe manic episode. Olanzapine is among the many antipsychotic agents associated with weight gain .
- Trial name
- NCT00191828
- Testing
- olanzapine
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Eli Lilly and Company
Diabetes Mellitus, Obesity
Efficacy of Laparoscopic Sleeve Gastrectomy and Intensive Medical Management in Obese Type 2 Diabetes
In this the investigators will be comparing the effects of Laparoscopic sleeve gastrectomy with intensive medical management on weight and metabolic parameters.
- Trial name
- NCT01429506
- Testing
- Sleeve gastrectomy, Intensive medical management
- Where
- India
- Volunteers
- 30 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Chronic Weight Management
Long-term Efficacy and Safety of HRS-7535 Tablets in Obese Subjects
The Objective of this trial is to evaluate the long-term safety, tolerability, weight loss efficacy and metabolic benefits of HRS-7535 tablets inobesity.
- Trial name
- NCT06671821
- Testing
- HRS-7535
- Where
- China
- Volunteers
- 81 people
- Sponsor
- Shandong Suncadia Medicine Co., Ltd.