Clinical trials: Bone Age Assessment
Fracture Fixation, Internal, Distal Radius Fracture
RemeOs™ DrillPin for Fixation of Distal Radius Fractures in Children
This is a pre-market, single-arm, open-label, monocenter clinical investigation evaluating the safety and performance of the magnesium (Mg)-based bioresorbable RemeOs™ DrillPin for surgical fixation of distal radius fractures in…
- Trial name
- NCT07028541
- Testing
- Magnesium-based bioresorbable DrillPin for fixation of distal radius fractures in children
- Volunteers
- 20 people
- Sponsor
- Bioretec Ltd.
Genu Varum, Genu Valgus
IMU-based Assessment of Motor Control in a Population of Young Subjects With Paramorphisms and Dysmorphisms
While various complex pathologies of the developmental age, such as Infantile Cerebral Palsy or Neuromuscular Diseases, are notoriously considered causes of alteration of locomotor development, it is scarcely known whether…
- Conditions
- Genu Varum, Genu Valgus, Flat Feet, Cavus Foot
- Trial name
- MOTOR-CHILD (NCT05763901)
- Testing
- Clinical tests and motor control evaluation using Inertial Measurement Units
- Where
- Italy
- Volunteers
- 151 people
- Sponsor
- Istituto Ortopedico Rizzoli
Acute Myeloid Leukemia, Myelodysplastic Syndrome
Mylotarg and Ara-C in Untreated Patients Above 60 Years With AML and High-Risk MDS
The purpose of this study is to find out how safe and effective the combination of Mylotarg in combination with cytarabine is in treating patients with Acute Myeloid Leukemia and advanced Myelodysplastic Syndrome over the age of…
- Trial name
- NCT00195000
- Testing
- Mylotarg, Cytarabine
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Weill Medical College of Cornell University
Rib Fractures, Rib Trauma
Investigation of the Effect of Age and Injury Severity on Short-term Intra-hospital Outcomes After Surgical Stabilized Rib Fractures
The study aims to investigate the effect of surgical stabilisation of rib fractures (SSRF) on clinical outcomes measured during the hospital stay (mortality, days on a mechanical ventilator, intensive care unit and hospital…
- Conditions
- Rib Fractures, Rib Trauma, Rib Fracture Multiple, Thorax; Fracture
- Trial name
- NCT06464302
- Testing
- Surgical stabilisation of rib fractures (SSRF), Non-operative management of rib fractures
- Where
- Germany
- Volunteers
- 1,064 people
- Sponsor
- University Hospital Muenster
Immunocompromised
H1N1sw Vaccine in Adult Transplant Recipients
The trial investigates the efficacy of the adjuvanted H1N1 influenza vaccine Focetria(R) in immunocompromised adults who have undergone solid organ or bone marrow transplantation.
- Trial name
- NCT01069601
- Testing
- Focetria (2x H1N1 vaccine with MF59 adjuvants)
- Where
- Germany
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- HepNet Study House, German Liverfoundation
Osteoporosis Fracture
Continuation of Anti-osteoporotic Treatment 1 Year After Initial Administration
The aim of this observational study is to assess the obstacles and levers to the continuation of anti-osteoporotic treatment, and to identify those where action could be taken to improve the quality of care for fractured…
- Trial name
- POUROSTEO (NCT06024148)
- Testing
- phone survey
- Volunteers
- 250 people
- Sponsor
- University Hospital, Grenoble
Slipped Capital Femoral Epiphysis
Evaluation of Skeletal Maturity for Slipped Capital Femoral Epiphysis
This study is being done for two reasons: 1) to evaluate growth problems in the hip in patients with Slipped Capital Femoral Epiphysis (SCFE) as they continue to grow into adults, and 2) to help doctors determine which patients…
- Trial name
- NCT01220882
- Testing
- Radiographic skeletal age assessment
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Rutgers, The State University of New Jersey
Acute Myeloid Leukemia
Bone Marrow Angiogenesis in Acute Myeloid Leukemia - Evaluated by Dynamic Contrast Enhanced Magnetic Resonance (MR) Image
In malignant or neoplastic disease, angiogenesis is defined as the generation of new capillaries from preexisting blood vessels, e.g. by sprouting or by intusseption.
- Trial name
- NCT00172562
- Where
- Taiwan
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Achondroplasia
A Clinical Trial to Evaluate the Safety and Efficacy of BMN 111 in Infants and Young Children With Achondroplasia
Study 111-206 is a Phase 2 randomized, double-blind, placebo-controlled clinical trial of BMN 111 in infants and young children with a diagnosis of achondroplasia.
- Trial name
- NCT03583697
- Testing
- BMN 111
- Where
- 16 sites in United States, Australia and 2 more
- Volunteers
- 75 people
- Sponsor
- BioMarin Pharmaceutical
Short Stature, Idiopathic, Infant, Small for Gestational Age
Evaluation of the Ease of Use, Preference, and Safety of EutropinPen Inj.
The purpose of this study is to assess the ease of use, preference, and safety after 8 weeks subcutaneous administration of EutropinPen Inj. in patients pretreated with recombinant human growth hormone by reusable device.
- Conditions
- Short Stature, Idiopathic, Infant, Small for Gestational Age, Growth Hormone Deficiency, Chronic Renal Failure
- Trial name
- NCT03015909
- Testing
- Somatropin
- Where
- South Korea
- Volunteers
- 116 people
- Sponsor
- LG Life Sciences
Overweight and Obesity, Body Composition
Aerobic Exercise and Body Composition in Overweight and Obese Boys.
Overweight and obesity are unhealthy fat accumulations. children aged 2-18 are deemed overweight if their body mass index (BMI)/Age is ≥ 85th - <95th percentile and obese if >95th percentile.
- Conditions
- Overweight and Obesity, Body Composition, Body Fat, Lean Body Mass
- Trial name
- NCT07586579
- Testing
- aerobic exercise
- Where
- Indonesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universitas Sriwijaya
Osteoporosis, Osteoporosis, Age-Related
Safety and Efficacy of Abaloparatide-SC in Men With Osteoporosis (ATOM)
A 12-month study to measure the efficacy and safety of abaloparatide in men with osteoporosis.
- Conditions
- Osteoporosis, Osteoporosis, Age-Related, Osteoporosis Localized to Spine, Age Related Osteoporosis
- Trial name
- NCT03512262
- Testing
- Abaloparatide
- Where
- 34 sites in United States, Italy and 1 more
- Volunteers
- 228 people
- Sponsor
- Radius Health, Inc.
Endocrine Diseases
Performance of the Diagnostic Value of Bone Age Assessment Software Based on Deep Learning in Chinese Children
High accuracy and precision bone age assessment is very important for the diagnosis and treatment monitoring of various pediatric diseases.
- Trial name
- NCT05137301
- Testing
- X-ray bone age instrument
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tongji Hospital
Anesthesia, Spinal, Hip Fractures
Haemodynamic Effects and Complications of Continuous Versus Single-shot Spinal Anaesthesia for HIP Fracture Surgery
This research project aims to identify a safer method of spinal anaesthesia for elderly patients undergoing surgical stabilisation of proximal femoral fractures.
- Trial name
- CHIPS (NCT07358299)
- Testing
- Bupivacaine Spinal 0,5% Heavy - bolus, Bupivacaine Spinal 0,5% Heavy - titration
- Where
- 2 sites in Poland
- Volunteers
- 216 people
- Sponsor
- Centre of Postgraduate Medical Education
Myelodysplasia
Allogeneic Hematopoietic Stem Cell Transplantation Evaluation in High Risk Myelodysplasia: an Observational Non-interventional Study
The purpose of this study is to compare outcome of high risk myelodysplasia patients aged from 50 to 70 years with or without HLA compatible (9 or 10 identities / 10) donor.
- Trial name
- ONIalloMDS (NCT01095874)
- Where
- France
- Volunteers
- 164 people
- Sponsor
- Saint-Louis Hospital, Paris, France
Scoliosis
Evaluation of the Surface Topography for Monitoring Scoliosis Patients Aged 10-13 Years
The main objective of the study is to investigate the correlation between the measurement of the Cobb angle (angle of scoliosis) by conventional radiography and angle measured by surface topography.
- Trial name
- SCOBIOMOD (NCT02531945)
- Testing
- Use of Biomod device
- Where
- France
- Volunteers
- 125 people
- Sponsor
- University Hospital, Toulouse
Pectus Excavatum, Pectus Carinatum
Psychological Assessment of Patients With Chest Wall Deformities
The study aims to investigate the most frequent psychological outcomes associated to chest wall deformities and patients' quality of life.
- Trial name
- NCT04362878
- Where
- Italy
- Volunteers
- 209 people
- Sponsor
- University of Florence
Arthritis, Psoriatic
Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response
This is a study to confirm the clinical efficacy and safety of sonelokimab compared with placebo in the treatment of adults with active psoriatic arthritis who have had a previous inadequate response or intolerance to anti-tumor…
- Trial name
- IZAR-2 (NCT06641089)
- Testing
- Sonelokimab, Risankizumab
- Where
- 143 sites in United States, Bulgaria and 9 more
- Volunteers
- 600 people
- Sponsor
- MoonLake Immunotherapeutics AG
Bone Age
Artificial Intelligence Assisted Bone Age Assessment
AI-Assisted Bone Age Assessment
- Trial name
- NCT07121283
- Testing
- True AI, Fake AI
- Where
- Taiwan
- Volunteers
- 8 people
- Sponsor
- Cheng-Hsin General Hospital
Bone Mineral Content, Bone Density
The KOMOtini BONE Study: Evaluation of the Osteogenic Potential of Sports
Bone mass develops throughout childhood and adolescence until a peak bone mass is achieved during early adulthood. Fracture risk later in life can be predicted at a large extent by peak bone mass.
- Conditions
- Bone Mineral Content, Bone Density, Bone Turnover Markers, Athletic Performance
- Trial name
- KOMO-BONE (NCT03201302)
- Testing
- School physical education class, Taekwondo, Martial arts
- Where
- Greece
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- Ioannis G. Fatouros