Clinical trials: Bone Aging
Sarcopenia, Osteoporosis
Acetaminophen and Impaired Musculoskeletal Adaptations to Exercise Training
The purpose of this study is to determine if taking the pain reliever acetaminophen (ACET) interferes with some of the benefits of weight lifting on muscles and bone density in older men.
- Conditions
- Sarcopenia, Osteoporosis, Aging
- Trial name
- NCT01083901
- Testing
- Resistance training
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Aging, Physical Fitness
Myogenic and Osteogenic Responses to eXercise and Ibuprofen
The purpose of this study is to determine if the use of ibuprofen blocks the benefits of exercise to build bone and muscle mass.
- Trial name
- MOXI (NCT00462722)
- Testing
- Ibuprofen, musculoskeletal-loading exercise
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Hormone Deficiency, Aging
Three Month Treatment of Growth Hormone Releasing Hormone (GHRH) in the Elderly
The purpose of the study is to evaluate the effect of a naturally occurring hormone, called Growth Hormone Releasing Hormone (GHRH) on the muscle, bone, and fat tissues of the body.
- Trial name
- NCT01410799
- Testing
- Growth Hormone Releasing Hormone (GHRH )
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Osteoporosis, Aging
Exercise Mode and Acute Bone Resorption
Endurance exercise is often recommended to improve cardiometabolic health and maintain bone health throughout life and to prevent osteoporotic fracture.
- Trial name
- NCT04815824
- Testing
- Exercise Mode
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Healthy Volunteers
Dose-Response of Gonadal Steroids and Bone Turnover in Older Men
The purpose of this study is to determine the levels of testosterone and/or estradiol at which changes in bone turnover, body composition, strength, sexual function etc. begin to occur in older men.
- Trial name
- NCT00114114
- Testing
- Testosterone, Goserelin acetate
- Where
- United States
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Myocardial Infarction, Stroke
Women's Health Initiative Strong and Healthy Study
The WHISH trial applies state-of-the science behavioral principles and currently available technologies to deliver a physical activity intervention without face-to-face contact to ~25,000 older U.S. women expected to consent.
- Conditions
- Myocardial Infarction, Stroke, Cardiovascular Mortality, Hip Fractures
- Trial name
- WHISH (NCT02425345)
- Testing
- Physical Activity
- Volunteers
- 49,331 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Postmenopausal Osteoporosis, Gut Microbiota
Blackcurrants Modify Gut Microbiota and Reduce Osteoporosis and CVD Risk
Aim to evaluate the effects of blackcurrant supplementation on changes in gut microbiome, bone mass, and CVD risk factors in adult women.
- Conditions
- Postmenopausal Osteoporosis, Gut Microbiota, Cardiovascular Diseases
- Trial name
- NCT04431960
- Testing
- blackcurrant (BC) extract
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Aging, Osteoporosis
Determinants of Vitamin K Metabolism
The purpose of this study is to learn how the body responds to different amounts of vitamin K in the diet in order to understand the roles that vitamin K may have in the body.
- Trial name
- NCT00336232
- Testing
- Vitamin K
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Tufts University