Clinical trials: Bone Atrophy
Bone Atrophy, Alveolar
Tooth Roots for Lateral Alveolar Ridge Augmentation
A deficient alveolar ridge segment in prepara¬tion for implant placement can be regenerated by several techniques. The type of graft material for each patient depends on many factors such as the anatomy, the morphology of the…
- Trial name
- NCT04678674
- Testing
- tooth root augmentation
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St. Catherine Specialty Hospital
Bone Atrophy, Alveolar
All-on-Four Implants With Ultrasonic
The objective of this observational study is the radiographic evaluation of marginal bone remodeling after surgical implant insertion in an immediate loading all-on-four technique with trans-sinusal titanium implants, correlating…
- Trial name
- Nobelsinus (NCT03357692)
- Testing
- all on four implant rehabilitation
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Alveolar Bone Atrophy
RCT With 3 Different Biomaterials for Maxillary Sinus Lift
Background: Lateral maxillary sinus augmentation (MSA) is a predictable bone regeneration technique in case of atrophy of the posterior-upper maxilla.
- Trial name
- NCT04506827
- Testing
- Maxillary Sinus Augmentation, Maxillary Sinus Graft with ABBM, Maxillary Sinus Graft with TCP
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- University of Pisa
Bone Atrophy
Reconstruction of Jaw Bone Using Mesenchymal Stem Cells
This pilot study is aimed to reconstruct atrophied posterior alveolar mandibular ridges using biomaterial and autologous bone marrow derived stem cells (BMMSC) and to insert an implant into the new bone in a prosthetically guided…
- Trial name
- NCT02751125
- Testing
- BCP with autologous mesenchymal stem cells (MSC).
- Where
- Norway
- Volunteers
- 13 people
- Sponsor
- University of Bergen
Osteoporosis, Sarcopenia
Effect of Potassium Bicarbonate Supplementation on Bone and Muscle in Older Adults
There is increasing evidence that the acid-base balance of diet plays an important role in the health of bones and muscles. An excess of acid in the body can result in calcium loss and muscle breakdown.
- Trial name
- NCT00357214
- Testing
- Potassium Bicarbonate, Sodium Bicarbonate, Potassium Chloride
- Where
- United States
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Tufts University
Edentulous Alveolar Ridge, Bone Atrophy, Alveolar
Crestal vs Lateral Sinus Lift Augmentation
The aim of this randomised controlled trial (RCT) of split-mouth design was to compare patient preference and effectiveness of two different techniques for lifting the maxillary sinus: the crestal approach versus the lateral…
- Trial name
- NCT04111250
- Testing
- Maxillary sinus augmentation
- Where
- Albania
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Hospital San Pietro Fatebenefratelli
Bone Cysts, Bone Atrophy
Gene-activated Bone Substitute for Maxillofacial Bone Regeneration
The purpose of this study is to evaluate the safety and efficacy of the gene-activated bone substitute consisting of octacalcium phosphate and plasmid DNA encoding vascular endothelial growth factor (VEGF) for maxillofacial bone…
- Conditions
- Bone Cysts, Bone Atrophy, Bone Deformity, Bone Fracture
- Trial name
- NCT03076138
- Testing
- Gene-activated matrix (OCP + plasmid DNA with VEGF gene)
- Where
- Russia
- Volunteers
- 20 people
- Sponsor
- Histograft Co., Ltd.
Bone Loss, Alveolar, Tooth Loss
Tooth Autotransplantation and Bone Dimension Changes
Tooth autotransplantation is a treatment option to replace tooth with imposible prognosis. In several cases the receipt site has a reduced bone dimension.
- Conditions
- Bone Loss, Alveolar, Tooth Loss, Bone Atrophy, Alveolar
- Trial name
- NCT03927937
- Testing
- AUTOTRANSPLANTATION TOOTH
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Universidad de Murcia
Bone Atrophy
Evaluation of Alveolar Augmentation Using Tunneling Surgical Technique
patients suffering from anterior maxillary horizontal bone defect the alveolar ridge will be augmented by minimally invasive tunneling technique utilizing MPM as bone graft and patients followed up for 14 weeks .
- Trial name
- NCT03498573
- Testing
- tunneling surgical technique
- Volunteers
- 10 people
- Sponsor
- Hussien Amer Elkady
Atrophy, Jaw, Edentulous, Partially
Comparative Results of Six Biomaterials Used in Two-stage Maxillary Sinus
Objectives: The aim of the study was to compare histological and histomorphometric results of six bone substitute materials used as graft in two-stage maxillary sinus augmentation model, after 6-month-healing.
- Conditions
- Atrophy, Jaw, Edentulous, Partially, Sinus Floor Augmentation, Bone Substitutes
- Trial name
- NCT03496688
- Testing
- Sinus floor augmentation
- Volunteers
- 6 people
- Sponsor
- University of Roma La Sapienza
Tooth Loss, Bone Atrophy
Sinus Lift: Saving Time and Reducing Morbidity
BACKGROUND Tooth loss impairs the OHRQoL. Dental implants have expanded treatment options of edentulous patients and improved their OHRQoL, however, in the posterior maxillary sextants the possibility to place implants of desired…
- Trial name
- SmartLiftRER (NCT02415946)
- Testing
- Sinus floor augmentation (lateral), Sinus floor augmentation (transcrestal)
- Where
- 2 sites in Italy
- Volunteers
- 57 people
- Sponsor
- University Hospital of Ferrara
Bone Atrophy, Alveolar
Conventional and Ultrasonic Implant Site Preparation
multi center study with randomized controlled trial design, split mouth
- Trial name
- PI-DRI (NCT03357406)
- Testing
- ultrasound implant site preparation, conventional implant site preparation
- Where
- Italy
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Muscle Atrophy, Weightlessness
The Effects of Whole Body Unloading on Physiological Function
This study is a collaboration between the Centre of Human \& Aerospace Physiological Sciences (CHAPS) and the Sleep and Brain Plasticity Centre (Department of Neuroimaging) at King's College London and the Sleep Disorders Centre…
- Conditions
- Muscle Atrophy, Weightlessness, Sleep Disturbance, Astronaut-Bone Demineralisation Syndrome
- Trial name
- NCT03195348
- Testing
- HBF Bed Rest
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- King's College London
Weight Loss, Muscle Loss
Effects of Dietary Protein on Musculoskeletal Health During Calorie Deficiency
Military personnel face many physiological challenges, including sustained physical activity and prolonged periods of negative energy balance.
- Conditions
- Weight Loss, Muscle Loss, Bone Loss
- Trial name
- NCT01292395
- Testing
- Dietary Protein Intake
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Alveolar Process Atrophy
Ridge Preservation With Provisional Ovoid Pontic
A prospective randomized controlled trial of 30 patients from the Faculty of Dentistry of the UFJF was conducted. It was included patients who presented indication of extraction of premolars, canines or incisors.
- Trial name
- NCT03166475
- Testing
- Surgical procedures
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Juiz de Fora
Muscle; Atrophy, General
The Effects of the Novel Unloading Device "HEPHAISTOS" on Bone, Muscles and Vessels
11 healthy men used the HEPHAISTOS unloading orthosis in an ambulatory 8 week intervention study. It greatly reduces calf muscle forces without reducing ground reaction forces.
- Trial name
- HEP (NCT03086187)
- Testing
- Hephaistos unloading orthosis
- Where
- Germany
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
Maxillofacial Bone Defects, Alveolar Bone Atrophy
Gene-activated Matrix for Bone Tissue Repair in Maxillofacial Surgery
The purpose of this study is to evaluate safety and efficacy of gene-activated matrix ("Nucleostim") for regeneration of bone tissue in maxillofacial area.
- Conditions
- Maxillofacial Bone Defects, Alveolar Bone Atrophy, Jaw Fractures, Maxillofacial Bone Deformities
- Trial name
- NCT02293031
- Testing
- Gene-activated matrix "Nucleostim"
- Where
- 2 sites in Russia
- Volunteers
- 12 people
- Sponsor
- NextGen Company Limited
Bone Diseases, Metabolic, Acid-Base Imbalance
The Effect of Potassium Bicarbonate on Bone and Several Physiological Systems During Immobilisation
Mainly due to the absence of gravitational forces in weightlessness, astronauts suffer from an increased bone loss- negatively affecting health and vitality during a mission.
- Conditions
- Bone Diseases, Metabolic, Acid-Base Imbalance, Muscular Atrophy, Sprains and Strains
- Trial name
- NUC (NCT01509456)
- Testing
- Potassium Bicarbonate
- Where
- Germany
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
Partially Edentulous Maxilla, Alveolar Bone Atrophy
Effectiveness and Safety of Method of Maxilla Alveolar Process Reconstruction Using Synthetic Tricalcium Phosphate and Autologous MMSCs
Autologous MMSCs will be isolated from oral mucosa biopsy sample and expanded in vitro.Tissue engineered construction will be created using synthetic tricalcium phosphate and autologous MMSCs.
- Conditions
- Partially Edentulous Maxilla, Alveolar Bone Atrophy, Alveolar Bone Loss
- Trial name
- NCT02209311
- Testing
- Oral mucosa biopsy, Sinus lift with implantation of tissue engineered construction, Dental implant
- Where
- 2 sites in Russia
- Volunteers
- 12 people
- Sponsor
- Central Clinical Hospital w/Outpatient Health Center of Business Administration for the President of Russian Federation
Alveolar Bone Loss, Atrophy
Buccal Fat Pad Derived Stem Cells With Cortical Tenting in Posterior Mandible Reconstruction
In this study the buccal fat pad derived stem cells (BFPSCs) is harvested from buccal fat pad tissue of the patients receiving posterior mandible augmentation.
- Trial name
- NCT02745366
- Testing
- BFPSC+FDBA+PRF, FDBA+PRF
- Where
- Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences