Clinical trials: Bone Density, active
Bone Density, Bone Health
VITamin D and OmegA-3 TriaL: Interrelationship of Vitamin D and Vitamin K on Bone (VITAL)
Vitamin D supplements are widely promoted for bone health. Both vitamin D and vitamin K are important for deposition of calcium in bone, but little is known about the relationship of vitamin K status and bone health.
- Conditions
- Bone Density, Bone Health, Fractures
- Trial name
- NCT04573946
- Testing
- Omega-3 fatty acids (fish oil), Vitamin D3
- Where
- United States
- Volunteers
- 25,871 people
- Sponsor
- Brigham and Women's Hospital
Osteoporosis
The Effect of Factors Affecting Bone Mineral Density Measurement Results on Osteoporosis Diagnosis and Treatment Decision
This is a single-center prospective cross-sectional study with a follow-up period of 6 months. All patients met the inclusion criteria and requested DXA at the outpatient clinics of Ankara Etlik City Hospital Physical Therapy and…
- Trial name
- NCT07812402
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Osteoporosis, Osteopenia
Serum Myostatin and Irisin Levels in Postmenopausal Women: Association With Bone Mineral Density and Muscle Strength
This study aims to evaluate the relationship between serum myostatin and irisin levels and bone mineral density and muscle strength in postmenopausal women.
- Trial name
- MYOIRISIN (NCT07519551)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Chronic Stroke, CONUT Score
Evaluation Of The Relationship Between The Conut Score And Balance And Functional Status In Patients With Chronic Stroke
The primary aim of this study is to evaluate the relationship between the CONUT score, which reflects nutritional status, and balance performance in patients with chronic stroke.
- Conditions
- Chronic Stroke, CONUT Score, Balance Assessment, Functional Status
- Trial name
- NCT07468110
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Marmara University
Low Bone Mineral Density, Muscle Oxygenation
Bone and Muscle Oxygenation in Military Test Pilots
This prospective, single-group interventional pilot study will evaluate the effects of a 12-week resistance and core stabilization exercise program on bone mineral density and resting muscle oxygenation in male military test…
- Trial name
- BMO-MTP (NCT07787143)
- Testing
- Supervised Resistance and Core Stabilization Exercise Program
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Emine Merve Ersever
Osteoporosis
The Effect of Denosumab on Muscle and Strength and Insulin Sensitivity
Randomized, placebo controlled prospective trial evaluating the effect of denosumab on insulin sensitivity and muscle strength.
- Trial name
- DENMUSIN (NCT07271771)
- Testing
- Denosumab, Saline (0.9% NaCl)
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Aarhus University Hospital
Osteopenia
AI-Supported Mobile High-Impact and Strengthening Exercise Program in Postmenopausal Women With Low Bone Density
Low bone mineral density after menopause increases the risk of osteoporosis and fractures, and regular exercise can help preserve bone health. However, adherence to home exercise programs is often low.
- Trial name
- NCT07918716
- Testing
- AI-Supported Mobile Health Application, Home-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Istanbul University
Immediate Implant Placement, Melatonin Production
Effectiveness of Topical Application of Melatonin On Bone Density and Implant Stability In Immediate Implantation
Dental implants have revolutionized the replacement of missing teeth, offering predictable and long-lasting rehabilitation for both fully and partially edentulous patients.
- Trial name
- NCT07003243
- Testing
- Local melatonin powder
- Where
- Iraq
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Calcium, Osteoporosis
A Study of Amorphous Calcium Carbonate in Postmenopausal Women
Using the FREEDOM substudy as a benchmark, evaluate the effects of amorphous calcium carbonate (ACC) on bone mineral density (BMD) in postmenopausal women, both with and without the combination of Denosumab treatment.
- Conditions
- Calcium, Osteoporosis, Bone Mineral Density, Bone Turnover Marker
- Trial name
- NCT06728462
- Testing
- Amorphous calcium carbonate
- Where
- Taiwan
- Volunteers
- 205 people
- Sponsor
- Universal Integrated Corp.
Spinal Cord Injury, Spinal Cord Injuries
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and…
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injury
- Trial name
- NCT04460872
- Testing
- Testosterone Enanthate, Locomotor Training
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- North Florida Foundation for Research and Education
Osteoporosis, Postmenopausal Osteoporosis
Can Serum Lumican Level Identify a Hidden Fragility Phenotype Beyond Bone Mineral Density in Postmenopausal Women?
Osteoporosis is a major cause of morbidity and fragility fractures in postmenopausal women. Bone mineral density (BMD) alone may not fully reflect fracture risk and skeletal fragility.
- Conditions
- Osteoporosis, Postmenopausal Osteoporosis, Frailty, Fragility Fractures
- Trial name
- LUMINOS (NCT07677072)
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Weight Loss, Bone Density
Metabolic Health, Bones and Nuts During Weight Loss in Adults
The aging population is rapidly increasing, and it is important to identify dietary factors that can prevent disease and promote health in this group.
- Conditions
- Weight Loss, Bone Density, Obesity and Overweight
- Trial name
- BERN (NCT06949280)
- Testing
- Peanut Snack Experimental, Nut-free Snack
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Arthritic Psoriasis, Psoriasis (PsO)
Retinal Capillary Vessel Density and Foveal Avascular Zone Size in Patients With Psoriatic Arthritis: A Case-Control Study.
In terms of blood flow per unit of tissue, the retina is one of the tissues with the highest blood flow in the body. Parameters such as the thickness of the choroid layer, which plays a crucial role in maintaining normal eye…
- Conditions
- Arthritic Psoriasis, Psoriasis (PsO), Retinal Vessels
- Trial name
- PsA-RETINA (NCT07858591)
- Testing
- OCTA-SCP, OCTA-DCP, OCTA-RPC
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Osteoporosis in Post-menopausal Women
Bone Health in Postmenopausal Women: The Effect of Exercise With or Without Medication for Osteoporosis
Osteoporosis is a systemic bone disorder characterised by a reduced bone mass and structural deterioration, increasing the risk of fragility fractures, particularly in women post-menopause.
- Trial name
- BEAT-OP (NCT07267325)
- Testing
- EXERCISE TRAINING, Antiresorptive medication (routine clinical care)
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Healthy, Indicated for EOSedge Imaging
Bone Mineral Density Agreement Study Between EOSedge™ Versus Traditional DXA
The purpose of this research is to collect medical imaging data to allow for the comparison of bone mineral density measurements from two different types of low-dose x-ray exams, EOSedge and conventional DXA.
- Trial name
- NCT06659055
- Testing
- DXA Imaging, EOSedge imaging
- Where
- 4 sites in United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Alphatec Spine, Inc.
Osteoporosis
Calibr-Ì: Comparative Evaluation of Phantomless Calibration Methods to Quantify Bone Mineral Density for Opportunistic Analysis of CT Scans
Osteoporosis is a systemic disease characterized by a reduction in bone mineral density (BMD) and qualitative alteration of the skeleton, resulting in increased bone fragility and fracture risk.
- Trial name
- Calibr-Ì (NCT06454617)
- Testing
- Phantom
- Where
- 2 sites in Italy, New Zealand
- Volunteers
- 100 people
- Sponsor
- Istituto Ortopedico Rizzoli
Radiographic Evaluation, Bone Density
Effect of Thymoquinone 0.2% Gel on Bone Density, Bone Width, and Socket Preservation After Tooth Extraction
This study aims to evaluate the clinical and radiographic effects of 0.2% Thymoquinone gel on bone density, bone width, and socket preservation after tooth extraction.
- Conditions
- Radiographic Evaluation, Bone Density, Bone Width, Socket Preservation
- Trial name
- NCT07765745
- Testing
- Gel foam, Thymoquinone gel + gel foam, Nano-formulated 0.2% thymoquinone gel + gel foam
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kafrelsheikh University
Anorexia Nervosa
Transdermal Estrogen in Women With Anorexia Nervosa
Randomized, placebo-controlled study investigating the use of physiologic, transdermal estrogen for low bone mass in adult women with anorexia nervosa.
- Trial name
- NCT03875378
- Testing
- Transdermal estrogen
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Pouneh K. Fazeli, MD
Mild Autonomous Cortisol Secretion (MACS)
Isturisa Treatment in Mild Autonomous Cortisol Secretion( MACS)
To characterize the impact of Isturisa on clinical features and comorbidities associated with MACS. The investigators hypothesize that patients treated with Isturisa will exhibit significantly better metabolic indicators (such as…
- Trial name
- NCT07247058
- Testing
- Osilodrostat (Isturisa)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Johns Hopkins University
Bone Density, Bone Level
Comparison Between Socket Shield and Conventional Techniques in Immediate Implant Placement.
The goal of this randomized clinical trial is to compare whether immediate implant placement using the socket-shield technique can better preserve bone density, bone level, and peri-implant tissue health compared to conventional…
- Conditions
- Bone Density, Bone Level, Peri-Implant Tissues, Socket Shield Technique Implant Placement
- Trial name
- NCT07761442
- Testing
- Conventional Technique, Socket-Shield Technique
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Minia University