Clinical trials: Bone Disease, Infectious
Oral Cavity, Osteomyelitis
The Influence of Bisphosphonates in the Oral Cavity in Children
The use of bisphosphonates during childhood to ameliorate the skeletal abnormalities associated with osteogenesis imperfecta, idiopathic juvenile osteoporosis, fibrous dysplasia of bone and cerebral palsy.
- Conditions
- Oral Cavity, Osteomyelitis, Necrosis of the Jaws
- Trial name
- NCT00402064
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Hadassah Medical Organization
Campylobacter Infections, Bone Diseases, Infectious
Retrospective Study of Bone Infection Due to Campylobacter Spp
Only 24 cases of Campylobacter bone and joint infection (BJI) have been reported worldwide between 1955 and 2008. Between 2010 and 2012, 7 cases were observed in two University hospitals in France.
- Trial name
- CAMPYLO (NCT02884752)
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Brest
Intervertebral Disc Degeneration, Intervertebral Disc Displacement
Proprio Spine Measurement Tool
This study will prospectively collect data to evaluate the effectiveness of a novel intraoperative spinal measurement system to assist the surgeon with intraoperatively achieving pre-planned alignment-related parameters to the…
- Conditions
- Intervertebral Disc Degeneration, Intervertebral Disc Displacement, Spinal Curvatures, Spinal Osteochondrosis
- Trial name
- NCT07023393
- Testing
- Intraoperative spinal measurement system
- Where
- United States
- Sponsor
- Duke University
Pneumonia, Syncope
Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC)
The Next Day Clinic (NDC) is a quality improvement initiative that will be launched and operated by UCLA Health starting July 22, 2024. Its goals are to improve patient care and safety and to maximize cost effectiveness.
- Conditions
- Pneumonia, Syncope, Congestive Heart Failure, Cellulitis
- Trial name
- NDC (NCT06526884)
- Testing
- Next Day Clinic
- Where
- United States
- Volunteers
- 570 people
- Sponsor
- University of California, Los Angeles
Osteomyelitis
RETR(Osteomyelitis)
This is a retrospective study describing the management of osteomyelitis in a referece center, with success and failures.
- Trial name
- NCT04936958
- Testing
- patients having had an osteomyelitis since 2017
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Mastoiditis; Acute
Corticosteroids as an Additional Treatment for Mastoiditis In Children
The aim of the study is to assess the influence of adjuvant corticosteroid treatment in acute mastoiditis in children. we expect a better outcome in children treated with both corticosteroids and antibiotics including lower rates…
- Trial name
- COSMIC (NCT04828525)
- Testing
- Dexamethasone, normal saline
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ori snapiri
Chronic Myeloproliferative Disorders, Leukemia
Flu Vaccine in Preventing Influenza Infection in Healthy Volunteers and in Patients Who Have Undergone Stem Cell Transplant
RATIONALE: Studying immune response to flu vaccine in patients who have undergone a stem cell transplant may help doctors plan the best treatment.
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00964821
- Testing
- trivalent influenza vaccine, Immunoenzyme technique, Laboratory biomarker analysis
- Where
- 2 sites in United States
- Volunteers
- 459 people, healthy volunteers welcome
- Sponsor
- City of Hope Medical Center
Diabetic Foot Ulcers, Diabetes Mellitus
Assessment of Non Vascular Risk Factors for Severity of Diabetic Foot Ulcers (DFUs)
Diabetes mellitus is a chronic disease that occurs either when pancreas does not produce enough insulin or when the body can't use it effectively.
- Trial name
- DFUs (NCT07193992)
- Volunteers
- 100 people
- Sponsor
- Assiut University
Infection; Diabetic Foot
Ertapenem Sodium (MK-0826) Versus Piperacillin/Tazobactam Sodium for the Treatment of Diabetic Foot Infections in Chinese Adults (MK-0826-061)
This study compared ertapenem sodium to piperacillin/tazobactam sodium for the treatment of moderate to severe diabetic foot infections.
- Trial name
- NCT01370616
- Testing
- Ertapenem sodium, Piperacillin/tazobactam sodium, Amoxicillin/clavulunate potassium
- Volunteers
- 565 people
- Sponsor
- Merck Sharp & Dohme LLC
COVID-19, SARS-CoV Infection
Seroprevalence Study of CoV-2-SARS (COVID-19) Infection in Patients With Chronic Inflammatory Rheumatic Diseases
The prevalence of SARS-CoV-2 infection in chronic inflammatory rheumatic diseases has not yet been widely reported, and has been evaluated only in symptomatic patient samples.
- Conditions
- COVID-19, SARS-CoV Infection, Rheumatoid Arthritis, Spondyloarthritis
- Trial name
- COVID-RIC1 (NCT04655612)
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- University Hospital, Montpellier
Osteomyelitis, Bone Infection
Clinical Effectiveness of S53P4 Bioactive Glass in Treatment of Long-bone Chronic Osteomyelitis
This clinical trial studies the clinical effectiveness of S53P4 bioactive glass (BAG) as a bacterial growth inhibiting bone graft substitute in a one-stage or two-stage surgical procedure for treatment of chronic long bone…
- Conditions
- Osteomyelitis, Bone Infection, Non-Union Fracture, Bone Infection of Lower Leg
- Trial name
- NCT04945434
- Testing
- S53P4 bioactive glass (BonAlive)
- Volunteers
- 78 people
- Sponsor
- Academisch Ziekenhuis Maastricht
Viral Infections
Retrospective Study of Viral Reactivation Across All Bone Marrow Transplant Protocols Since 2010
Background: Some blood and immune disorders can be helped with HSCT. This is allogeneic hematopoietic stem cell transplantation. The person who gets the stem cells has their immune system suppressed.
- Trial name
- NCT03111745
- Where
- United States
- Volunteers
- 730 people
- Sponsor
- National Cancer Institute (NCI)
Musculoskeletal Infection, Septic Arthritis
Infrared Thermography for Diagnosis of Musculoskeletal Infections
This is a pilot proof of feasibility study to explore the efficacy of High Resolution Infrared Thermographic Imaging (HRTI) to assist with the detection of musculoskeletal infections in children.
- Conditions
- Musculoskeletal Infection, Septic Arthritis, Osteomyelitis/Septic Arthritis
- Trial name
- NCT07388017
- Testing
- High Resolution Thermal Imaging
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Sheffield Children's NHS Foundation Trust