Clinical trials: Bone Fracture, active
Vertebra Compression Fracture
A Clinical Study to Collect Real-wordt Data on Safety and Clinical Performance of the VCFix Spinal System for Treatment of Vertebral Compression Fractures of (Suspected) Osteoporotic Origin.
This study is designed as a prospective, post-market, multi-center, single-arm study to collect real-world data of the VCFix Spinal System used in US clinical practice.
- Trial name
- EXPAND-US (NCT07920484)
- Testing
- VCFix Spinal System in stand-alone configuration
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Amber Implants B.V.
Orthopaedic Fractures, Socioeconomic Factors
Trial of Social Work Services in Fracture Clinic Setting
Every year, many Canadians sustain a fracture that requires surgical treatment and results in a long recovery period. During this recovery period, patients may experience new or worsening mental health issues including…
- Trial name
- SWRCT (NCT06973655)
- Testing
- Social Work support
- Where
- 2 sites in United States, Canada
- Volunteers
- 2,000 people
- Sponsor
- Sheila Sprague
Periarticular Bone Defect, Proximal Humerus Fracture
Magnesium Alloy Scaffold With Controlled Degradation for Periarticular Bone Defects
This prospective, multi-center, randomized controlled clinical trial is designed to evaluate the effectiveness and safety of a biodegradable magnesium alloy scaffold with controlled degradation for the treatment of periarticular…
- Conditions
- Periarticular Bone Defect, Proximal Humerus Fracture, Distal Radius Fracture, Tibial Plateau Fracture
- Trial name
- MgScaf-PBD (NCT07906730)
- Testing
- Magnesium Alloy Scaffold, Calcium Sulfate Bone Graft Substitute
- Where
- 4 sites in China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Developmental Dysplasia of the Hip, Acetabular Bone Loss
3D-Printed Pelvic Models for Planning Complex Total Hip Arthroplasty
Total hip arthroplasty (THA) in patients with complex acetabular anatomy can be challenging because of abnormal bone structure, deformity, or bone loss.
- Conditions
- Developmental Dysplasia of the Hip, Acetabular Bone Loss, Acetabular Fracture
- Trial name
- NCT07904637
- Testing
- Conventional Imaging-Based Preoperative Planning, CT-Based 3D-Printed Pelvic Model-Assisted Planning
- Where
- Egypt
- Volunteers
- 15 people
- Sponsor
- Ain Shams University
Type 2 Diabetes, Osteoporosis
Impact of Screening and Multicomponent Exercise on Fall Rates, Fractures, and Cardiovascular Health in Diabetes
The DIACTIVE study is a randomized controlled trial with a 5- year follow-up designed to evaluate the impact of comprehensive screening and multicomponent interventions on fall prevention, bone health, nerve function and…
- Conditions
- Type 2 Diabetes, Osteoporosis, Diabetic Neuropathies, Fall Prevention
- Trial name
- DiaACTIVE (NCT06745544)
- Testing
- Rhythm- and Multitask-Based Activity (RYMA) and Activities of Daily Living (ADL)
- Where
- Denmark
- Volunteers
- 490 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Fracture, Erosion
Evaluation of the Diagnostic Potential of Nanox.ARC Tomosynthesis System for Different Diseases
This is a prospective, single-arm, clinical study evaluating the diagnostic performance of the Nanox.ARC Digital Tomosynthesis (DTS) system in adult patients with suspected or confirmed musculoskeletal (MSK) pathologies…
- Trial name
- Nan-05 (NCT07900412)
- Testing
- Nanox.ARC Digital Tomosynthesis System
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Nano-X Imaging
Bone Stress Fracture
Bone Stress Injury Recovery and Return to Sport: A Natural History Study
Lower extremity bone stress injury (BSI) is a common overuse injury in athletes and typically requires 4-12 weeks rehabilitation time, provided the injury does not require surgery.
- Trial name
- NCT07902401
- Where
- 4 sites in United States, Canada
- Volunteers
- 105 people
- Sponsor
- HealthPartners Institute
Opioid Use, Fractures, Bone
Nonopioid Pain Control Regimen After Open Reduction and Internal Fixation of Traumatic Fractures
An open reduction and internal fixation is a painful procedure requiring intensive postoperative pain management. Traditionally, opioid analgesia has been the gold standard for postoperative pain control.
- Conditions
- Opioid Use, Fractures, Bone, Trauma
- Trial name
- NCT06113211
- Testing
- Narcotic pain medication, Nonnarcotic pain medications
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Henry Ford Health System
Hand Fractures
Repair of Extra-articular Fractures of the Metacarpals and First Phalanges of the Long Fingers
The goal of this randomized controlled trial is to compare the effectiveness, complications, and cost-effectiveness of three surgical techniques (intramedullary screw fixation, locked plating, and percutaneous pinning) for…
- Trial name
- FinXger (NCT07186829)
- Testing
- Percutaneous pinning, Locked plate, Intramedullary screw
- Where
- France
- Volunteers
- 111 people
- Sponsor
- University Hospital, Montpellier
Wrist Fracture
Wrist Reduction Intervention: Supracondylar Technique for Radial Nerve Block vs. Hematoma Block (WRIST Block Study)
The purpose of this study is to compare different types of local anesthesia-a supracondylar radial nerve block, a hematoma block, or a combination of the two-for reducing pain in people with a broken wrist (distal radius…
- Trial name
- NCT07268547
- Testing
- Supracondylar radial nerve block, Hematoma block, Combination of blocks
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Sarasota Memorial Health Care System
Non-inflammatory Degenerative Joint Disease, Rhematoid Arthritis
Tornier Perform™ Reversed Monopost Study
This study is a Multi-center, Prospective Follow-up, Non-significant risk, Post-Market Clinical Follow-Up (PMCF) study to Evaluate the Safety and Effectiveness of the Tornier Perform™ Reversed MonoPost System.
- Conditions
- Non-inflammatory Degenerative Joint Disease, Rhematoid Arthritis, Correction of Functional Deformity, Fracture of the Humeral Head
- Trial name
- Monarch (NCT07764614)
- Testing
- Tornier Perform™ Reversed MonoPost
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Stryker Trauma and Extremities
Pain, Appendicitis
PAINED: Project Addressing INequities in the Emergency Department
Racial and ethnic inequities in health care quality have been described across a broad range of clinical settings, patient populations, and outcomes.
- Conditions
- Pain, Appendicitis, Bias, Racial, Fractures, Bone
- Trial name
- PAINED (NCT05488080)
- Testing
- Department-level audit and feedback and electronic health record-embedded clinical decision support
- Where
- United States
- Volunteers
- 22,032 people
- Sponsor
- Children's National Research Institute
Postoperative Pain, Rebound Pain
Nerve Block Resolution Time Display and Pain Complaints
This randomized prospective study will evaluate whether displaying the expected nerve block resolution time on a patient's splint reduces postoperative pain-related complaints after orthopedic surgery.
- Conditions
- Postoperative Pain, Rebound Pain, Fracture
- Trial name
- NCT07887516
- Testing
- Physical display
- Volunteers
- 128 people
- Sponsor
- Medical University of South Carolina
Abdominal Pain, Isolated Extremity Fracture
Morphine or Ketamine for Analgesia
Pain is common in children presenting to the emergency department but is frequently undertreated, leading to both short- and long-term consequences.
- Conditions
- Abdominal Pain, Isolated Extremity Fracture, Pain, Pediatrics
- Trial name
- MoKA (NCT06835504)
- Testing
- Ketamine hydrochloride, Morphine sulphate
- Where
- 8 sites in United States
- Volunteers
- 1,010 people
- Sponsor
- Columbia University
Endosseous Dental Implant Failure, Accident Caused by Broken Ceramic
Full-Contour Monolithic Zirconia Full-Mouth Implant Supported Rehabilitation Behavior
In patients who received a full-mouth implant-supported rehabilitation restored with CAD/CAM full-contour monolithic zirconia (FCMZ, without buccal ceramic veneer; veneering, if present, limited to the gingival area), what is the…
- Trial name
- FCMZ (NCT07876466)
- Testing
- Dental Implant, Monolithic Zirconia (FCMZ)
- Where
- Portugal
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Proximal Humerus Fracture
Study on Outcomes of Proximal Humerus Fractures
Patients undergoing either operative or non-operative treatment of proximal humerus fractures will be studied with the goal of understanding which treatment modality provides optimal post-injury outcomes.
- Trial name
- NCT07060664
- Testing
- open reduction internal fixation, intramedullary nail, reverse total shoulder arthroplasty
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Massachusetts, Worcester
Endosseous Dental Implant Failure, Accident Caused by Broken Ceramic
Monolithic Zirconia Full-Mouth Implant Supported Rehabilitation Behavior
In patients rehabilitated with a full-arch (maxillary and/or mandibular) implant-supported fixed prosthesis, do three CAD/CAM zirconia framework designs - porcelain-veneered zirconia (PVZ), monolithic zirconia with buccal veneer…
- Trial name
- NCT01974362
- Testing
- Dental Implant, Monolithic Zirconia (MZ), Zirconia-Feldspathic (PVZ)
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Fracture Arm, Fracture Leg
Accuro XV Ultrasound Imaging System for BoneEnhance and Fracture Detection Algorithms
The Accuro XV is a cart-based, bedside ultrasound instrument that incorporates new signal processing-based technologies for enhanced bone and soft-tissue imaging.
- Conditions
- Fracture Arm, Fracture Leg, Wrist Injury, Ankle Injury
- Trial name
- NCT07853768
- Testing
- Accuro XV Ultrasound Imaging System
- Where
- 10 sites in United States
- Volunteers
- 25,000 people
- Sponsor
- Rivanna Medical, Inc.
Osteoporosis Diagnosis, Bone Health
REMS vs DXA for Osteoporosis Diagnosis and Fracture Risk Prediction
This prospective, observational, comparative diagnostic study will evaluate the performance of Radiofrequency Echographic Multi Spectrometry (REMS) for the diagnosis of osteoporosis and prediction of fragility fracture risk in a…
- Conditions
- Osteoporosis Diagnosis, Bone Health, Fracture
- Trial name
- NCT07876882
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- BoneVue Diagnostics
Atypical Femur Fracture
Quebec Registry for Atypical Femur Fractures
Bisphosphonates are recommended as first-line agents to reduce fracture risk in patients with osteoporosis and have in general an excellent safety profile.
- Trial name
- NCT02150850
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- McGill University