Clinical trials: Bone Fractures
Dementia, Hip Fractures
Care Delivery in Acute Hospital Settings: an Observational Study
This small observational study is a contractual component of a 5-year (2013-18) NIHR funded programme called PERFECTED (Peri-operative Enhanced Recovery hip FracturE Care of paTiEnts with Dementia) whose overall aim is to develop…
- Trial name
- PERFECTED (NCT02212353)
- Testing
- Observational study, not interventional
- Volunteers
- 180 people
- Sponsor
- University of East Anglia
Osteoporosis
Study in Patients With Osteoporosis and Fragility Fractures to Estimate the Extent and Impact of Delayed Administration of Anti-fracture Therapy
Osteoporosis (OP) and fragility fractures are a significant problem that leads to morbidity, mortality, and high costs for the National Health System.
- Trial name
- OPGAP01 (NCT07512453)
- Where
- Italy
- Volunteers
- 8,000 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Fractures
Efficacy of Sublingual Midazolam in Association With Oral Morphine in Children Analgesia After Bone Fracture
It is a randomized simple-blind monocentric study; the group A will receive oral morphine with placebo and the group B will receive oral morphine with sublingual midazolam.
- Trial name
- MIDAZODOL (NCT00416039)
- Testing
- Midazolam
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Tibial Fracture
Tibial IMN Vs. Tibial Micromotion IMN
Our null hypothesis is that micromotion tibial intramedullary fixation (IMFN) does not impact union or complication rates when compared to standard of care treatment with non-micromotion tibial nail fixation.
- Trial name
- NCT06976801
- Testing
- Intramedullary tibial Nail, Intermedullary nail
- Where
- United States
- Volunteers
- 372 people
- Sponsor
- University of Chicago
Fracture of Medial Malleolus
Clinical Application of Mg Based Biodegradable Material for Fracture Fixation in the Adult Skeleton
This study is a prospective, non-randomized trial for the treatment of fractures of the medial malleolus using lean, bioabsorbable, rare-earth element (REE) free, magnesium (Mg)-based biodegradable screws in the adult skeleton.
- Trial name
- NCT05245981
- Testing
- BRI.MAG 2
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- Medical University of Graz
Osteotomy, Trochanteric Fractures
ZNN Bactiguard Cephalomedullary Nails PMCF Study
This is a multicenter, prospective, Post-market Clinical Follow-up (PMCF) Study on the ZNN Bactiguard Cephalomedullary Nails. The objective of this study is to collect data confirming the safety, performance, and clinical benefit…
- Conditions
- Osteotomy, Trochanteric Fractures, Sub-trochanteric Fractures, Femoral Shaft Fracture
- Trial name
- NCT05362864
- Testing
- Fracture fixation via Intramedullary Nailing
- Where
- 3 sites in France, Spain
- Volunteers
- 149 people
- Sponsor
- Zimmer Biomet
Osteoporotic Fractures
Cortical Bone Assessment Using Ultrasonic Guided Waves: Towards a Robust Clinical Measurement
Osteoporosis is a skeletal disease leading to bone fragility and increasing the risk of fractures and still remains a major public health problem worldwide.
- Trial name
- BDATChile (NCT05424536)
- Testing
- Bone measurement by DXA and ultrasound
- Where
- Chile
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Ankle Fractures
Impact of Suture Technique on Wound Healing in Ankle Fracture Surgery: A Randomized Controlled Trial
Our primary aim is to compare the complication rates of patients with ankle fractures who underwent skin closure using a running subcuticular suture pattern compared to an interrupted suture pattern.
- Trial name
- NCT06496698
- Testing
- Simple Interrupted Suture, Subcuticular Suture
- Volunteers
- 80 people
- Sponsor
- University of Puerto Rico
Hip Fracture
A Randomised, Controlled Comparison of Vitamin D Strategies is Acute Hip Fracture Patients
The purpose of the study is to determine the best dose of Vitamin D to give to hip fracture patients to achieve the optimal therapeutic level.
- Trial name
- NCT00424619
- Testing
- Vitamin D2
- Volunteers
- 64 people
- Sponsor
- McMaster University
Proximal Humeral Fractures
Hip-allograft In Proximal Humerus Fractures Versus Plate Implantation Alone: a Randomized Controlled Trial
Proximal humerus fractures (PHFs) are common osteoporotic fractures in adults and the elderly, leading to significant disability and reduced quality of life.
- Trial name
- HIPPI (NCT07538700)
- Testing
- Locking plate fixation with femoral allograft augmentation
- Where
- Netherlands
- Volunteers
- 56 people
- Sponsor
- Tergooi Medical Center
Periprosthetic Fracture Around Prosthetic Joint Implant, Aseptic Loosening of Prosthetic Joint
Follow-Up of the Prevision® Hip Stem
The main objective of this study is to represent the treatment reality at the study site and to draw conclusions from cases of failure or suboptimal outcome.
- Trial name
- PRESPECT (NCT04833634)
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- Aesculap AG
Unstable Intertrochanteric Hip Fractures
INTUIT Hip Fracture Outcome Study
The primary objective of this study is to characterize patients' course of recovery in the year following the initial surgery for unstable intertrochanteric hip fractures treated with the InterTAN intramedullary hip screw device.
- Trial name
- INTUIT (NCT00595634)
- Where
- 5 sites in United States
- Volunteers
- 92 people
- Sponsor
- Smith & Nephew, Inc.
Tibial Fractures
Efficacy Study of Surgical Technique in Intramedullary Tibia Nailing, Using Trigen META Tibia Nails
Multicentre Prospective Randomized Clinical Trial, to evaluate patients after surgery for extra-articular tibial fractures treated with Smith\& Nephew's Trigen META intramedullary nailing system; comparing two surgical…
- Trial name
- TrigenMETA (NCT01358292)
- Testing
- Semi-extended Surgical Technique, Standard Surgical Technique
- Where
- 5 sites in Germany, Spain and 1 more
- Volunteers
- 95 people
- Sponsor
- Smith & Nephew Orthopaedics AG
Lower Extremity Fractures
Insole Sensor to Determine Optimal Limb Loading
The purpose of this study is to use a novel load monitoring technology to correlate limb loading to OTA type 42IIIB and IIIC tibial fracture outcomes.
- Trial name
- NCT02170493
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Utah
Femoral Neck Fractures
Using Alternative Implants for the Surgical Treatment of Hip Fractures (The FAITH Study)
Each year, hip fracture, an injury that can impair independence and quality of life, occurs in about 280,000 Americans and 36,000 Canadians.
- Trial name
- NCT00761813
- Testing
- Open reduction internal fixation (ORIF) with single sliding hip screw, ORIF with multiple cancellous screws
- Where
- 32 sites in United States
- Volunteers
- 1,108 people
- Sponsor
- University of Minnesota
Chronic Renal Failure, Kidney Transplant Patients
Study of Trabecular Bone Score (TBS) as a Fracture Risk Factor in Chronic Renal Failure
Observational study
- Trial name
- TRIFIR (NCT03356522)
- Where
- France
- Volunteers
- 206 people
- Sponsor
- Rennes University Hospital
Acetabulum Fractures
Hemostasis in Open Acetabulum and Pelvic Ring Surgery Using Tranexamic Acid
This study is investigating the use of tranexamic acid (TXA) in patients with pelvis and/or hip socket fractures that require surgery.
- Trial name
- TXA (NCT02051686)
- Testing
- Tranexamic Acid
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Missouri-Columbia
Orbital Fractures
Orbital Fractures Measurement: Intraoperative Versus Computed Tomography (CT) Scan
Purpose to compare the orbital fracture size measured by orbital CT scan and compare it to the actual orbital fracture size intraoperatively in patients who needed surgical intervention to correct the fracture.
- Trial name
- NCT01464541
- Testing
- operative fracture size vs CT fracture size, orbital fracture intraoperative measurement
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- HaEmek Medical Center, Israel
Distal Radius Fracture, Postoperative Pain
Regional or General Anesthesia for Distal Radius Fracture Surgery in a Day Surgery Setting
The purpose of this study is to compare general and regional anesthesia with regard to postoperative pain in patients who undergo surgery in a day surgery setting due to a displaced distal radius fracture.
- Trial name
- NCT02495688
- Testing
- Regional anesthesia, General anesthesia
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Unilateral Tibial Diaphyseal Fracture
Tibial Fracture - Platelet-rich Plasma and Bone Marrow Concentrate
A prospective, randomised study is to investigate the feasibility of conducting a superiority randomised controlled trial comparing the application of combined autologous PRP and concentrated autologous bone marrow (PRP-BMA) in…
- Trial name
- T-PAC (NCT03100695)
- Testing
- Concentrated autologous PRP-BMA
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- University of Leeds