Clinical trials: Bone Mass
Osteoporosis
The Effects of Ibandronate or Teriparatide Therapy on Bone Histology and Biochemical Indices in Patients on Hemodialysis With Low Bone Mineral Density
Hemodialysis patients with low bone density (total hip T-score <-2.5) will be assigned to receive teriparatide (those with histologic confirmation of adynamic bone disease) or ibandronate (subjects with increased osteoclast…
- Trial name
- NCT00446589
- Testing
- ibandronate, teriparatide
- Where
- Greece
- Volunteers
- 19 people
- Sponsor
- Papageorgiou General Hospital
Postmenopausal Osteoporosis
Resolution of Effect of Bisphosphonates on Bone in Postmenopausal Osteoporosis
This is a 2year observational study that will recruit patients who have previously completed a randomised, open label, parallel, single centre study (TRIO Study) of three bisphosphonates: alendronate, ibandronate and risedronate.
- Trial name
- NCT01406613
- Testing
- Observation
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Bone Density
Bone Density in Voluntary Apheresis Blood Donors
A longitudinal, randomized, controlled, single-center Phase IV clinical trial will be performed to assess changes in bone mineral density (BMD) among voluntary apheresis blood donors.
- Trial name
- ALTRUYST (NCT02655055)
- Testing
- high frequency voluntary apheresis blood donation
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Versiti Blood Health
Ovarian Cancer
Bone Health in Gynecologic Cancers-does FOSAVANCE Help?
Women who undergo bilateral oophorectomy and receive chemotherapy are at risk of increased bone loss. At present, despite having a risk factor profile that fits the indications for assessment and treatment there are no routine…
- Trial name
- FOSAVANCE (NCT00593580)
- Testing
- alendronate/cholecalciferol
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- British Columbia Cancer Agency
Bone Mass, Effects of Vibration
Effects of Unilateral WBV on Muscleactivity of Contralateral Hip Adductor
The aim of this study is to investigate effects of femur exposed to unilateral vibration on the rest muscle electrical activity of contralateral hip adductors and contralateral soleus H-reflex in young adult men.
- Trial name
- WBV-BM (NCT01419782)
- Testing
- Whole-body vibration
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bagcilar Training and Research Hospital
Obesity, Osteoporosis
Bone Metabolism After Bariatric Surgery
The purpose and objective of this study is to determine the changes in bone metabolism after bariatric surgery in postmenopausal women.
- Trial name
- NCT01824797
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Duke University
Vitamin D Deficiency
The Impact of Severe Vitamin D Deficiency and Its Correction on Bone Mineral Density (BMD) in Postmenopausal Women
It is well known that postmenopausal women are at risk for osteoporosis. The study hypothesis is that vitamin D deficiency (≤17.5nmol/L) is frequently associated with osteomalacia and will cause low BMD estimation in DXA scan due…
- Trial name
- Vitamin D (NCT01694355)
- Testing
- Vitamin D
- Where
- Israel
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Alveolar Bone Loss, Bone Density Increased
Minimally Invasive Ridge Augmentation
The present study is a human, prospective, randomised controlled clinical trial conducted to explore the outcome of a minimally invasive ridge augmentation technique with and without low level laser therapy.
- Trial name
- NCT04190576
- Testing
- Low Level Laser Therapy
- Where
- India
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Femur Fracture
Combined Drug Therapy in Lateral Fragility Fractures of the Femur
It was conducted a prospective study with a series of 50 patients treated by intramedullary nail using Clodronic acid and Vitamin D (study group including 25 patients) and patients with the same fractures treated with Vitamin D…
- Trial name
- NCT05183308
- Testing
- Clodronic Acid
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari
Marfan Syndrome
Losartan Versus Atenolol for the Treatment of Marfan Syndrome
Marfan syndrome is a genetic disease of our connective tissue, which provides material and support for our skeleton, muscles, blood vessels and other parts of our bodies.
- Trial name
- NCT00593710
- Testing
- Losartan, Atenolol
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- University of British Columbia
Non-small Cell Lung Cancer
Efficacy and Safety of HGXJT in Bone Metastatic NSCLC Patients
This is a double-blind, randomized controlled study evaluating the efficacy and safety of HGXJT in combination with ICI-based standard treatment in lung cancer patients with bone metastases.
- Trial name
- NCT05378334
- Testing
- ICI, Chemotherapy, Bone-protecting and Mass-dispersesing Decoction
- Where
- China
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Guangzhou University of Traditional Chinese Medicine
Low Bone Mineral Density, Osteopenia
A Multi-Center, Randomized, Open-Label Study to Assess the Immunogenicity and Safety of Denosumab in Pre-filled Syringe Compared to Vial in Subjects With Low Bone Mineral Density
The purpose of this study is to compare the immunogenicity profiles of denosumab pre-filled syringe (PFS) and vial at 6 months in postmenopausal women with low bone mineral density (BMD).
- Conditions
- Low Bone Mineral Density, Osteopenia, Osteoporosis
- Trial name
- NCT00515463
- Testing
- denosumab
- Volunteers
- 311 people
- Sponsor
- Amgen
Type 2 Diabetes
Effects of DPP-4 Inhibition on Calcium and Bone Metabolism in Type 2 Diabetes Mellitus
Participants will be persons with Type 2 Diabetes who are likely to have increased risk of bone fractures. The investigators believe this medication will enhance bone turnover.
- Trial name
- NCT02444364
- Testing
- Sitagliptin
- Where
- United States
- Sponsor
- University of Missouri-Columbia
Pituitary ACTH Hypersecretion, Acromegaly
Vitamin D Metabolism in Patients With Endocrine Disorders
This prospective controlled interventional study aims to reveal the diversity of vitamin D metabolism in patients with certain endocrine disorders (Cushing's disease, acromegaly, primary hyperparathyroidism, diabetes mellitus…
- Conditions
- Pituitary ACTH Hypersecretion, Acromegaly, Diabetes Mellitus, Type 1, Primary Hyperparathyroidism
- Trial name
- NCT04844164
- Testing
- Cholecalciferol 15000 UNT/ML Oral Solution
- Where
- Russia
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- Endocrinology Research Centre, Moscow
Femoral Neck Fractures, Bone Mineral Density
Surgical Approach in Hemiarthroplasty. A Randomized Clinical Trial Comparing Posterior and Anterior Approach
Dislocated femoral neck fractures are routinely treated with cemented hemiartroplasty and the direct lateral approach (Hardinge) has commonly been used in Norway.
- Conditions
- Femoral Neck Fractures, Bone Mineral Density, Muscle Damage, Surgical Approach
- Trial name
- NCT04900506
- Testing
- Posterior SPAIRE approach, anterior approach
- Where
- 2 sites in Norway
- Volunteers
- 210 people
- Sponsor
- Sorlandet Hospital HF
Osteoporosis, Obesity
Breastfeeding and Exercise for Healthy Infants and Postpartum Moms Too!
Approximately 8 million American women suffer from osteoporosis, and one out of every two women over the age of 50 will have an osteoporotic-related fracture in their lifetime (42).
- Conditions
- Osteoporosis, Obesity, Weight Loss
- Trial name
- BEHIP (NCT00966381)
- Testing
- Exercise and weight loss intervention
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro
Systemic Lupus Erythematosus
Steroid Induced Osteoporosis in Patients With Systemic Lupus Erythematosus
The primary aim of the present study was to investigate the prevalence of low bone mineral density (BMD) and vertebral fractures, as determined by a standardized assessment, and to elucidate the role of bone qualities, including…
- Trial name
- NCT00668330
- Testing
- Ibandronate+alfacalcidol+calcium
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Implant Site Reaction
Bone Density and Marginal Bone Height Changes Around Dental Implants
The increased benefits to the edentulous population from implant supported overdenture is overwhelming in terms of better quality of life, emotional stability, improved function, enhanced esthetics and clinical comfort.1-6…
- Trial name
- NCT06151314
- Testing
- Dental implants.
- Where
- 2 sites in Egypt
- Volunteers
- 18 people
- Sponsor
- National Research Centre, Egypt
Osteopenia
DXA Precision and Accuracy Comparison Study
This study is being conducted to examine the performance of three common DXA machines (1) Lunar iDXA, (2) Lunar Prodigy and (3) Hologic Discovery A in measuring bone density and body fat.
- Trial name
- DXA P&A (NCT01530477)
- Testing
- Lunar Prodigy (GEHC), Lunar iDXA (GEHC), Discovery A (Hologic
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Calcium, Osteopenia
Effects of Amorphous Calcium Carbonate Supplementation on Bone Health in Postmenopausal Women With Osteopenia
This research was designed in accordance to the Method for Efficacy Assessment of Health Food for Bone Heath. Changes to bone density were measured to evaluate the effectiveness of amorphous calcium carbonate in maintaining bone…
- Conditions
- Calcium, Osteopenia, Bone Mineral Density, Bone Turnover Marker
- Trial name
- NCT05810909
- Where
- Taiwan
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universal Integrated Corp.
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