Clinical trials: Bone Mass
Arthropathy of Hip
Study Comparing BoneMaster Hydroxyapatite Coating With Plasma-sprayed Hydroxyapatite Coating on Acetabular Cups
The randomised controlled trial will be carried out on patients that require a total hip replacement (THR) to reduce pain and restore their function.
- Trial name
- NCT00859976
- Testing
- BoneMaster coated acetabular shell., Plasma Coated Acetabular Shell
- Where
- United Kingdom
- Volunteers
- 167 people
- Sponsor
- Zimmer Biomet
Type 2 Diabetes Mellitus, Bone Fractures
Microarchitecture, Bone Strength and Fracture Risk in Type 2 Diabetes
This multicenter, prospective, observational cohort study will assess bone differences in women and men with type 2 diabetes mellitus (T2DM) with and without fragility fractures.
- Trial name
- DiabOS (NCT02551315)
- Where
- 5 sites in Switzerland
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
HIV, Osteoporosis
Fracture and Bone Mineral Density in HIV+ Patients Recently Started on Antiretroviral Therapy (ART)
In a group of HIV-positive patients under observation since their first exposure to ART or monitored off of ART, BMD changes over one year will be determined.
- Trial name
- NCT01591252
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Alabama at Birmingham
Fractures, Osteoporosis
Effectiveness of an Educational Program in the Prevention of Osteoporosis and Fractures
The study will elucidate the effectiveness of an educational program in the prevention of osteoporosis and fractures. A random sample of the female population in Southern Finland (Uusimaa region) within the age group of 60-70…
- Trial name
- NCT00589615
- Testing
- multidisciplinary osteoporosis prevention educational program
- Where
- Finland
- Volunteers
- 2,181 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Marfan Syndrome
Adapted Physical Activity Program (APA) for Effort Rehabilitation of Children and Teenagers With Marfan Syndrome
This research study aims to evaluate the effect of a 6-month adapted physical activity program (APA) on the endurance capacities (evaluated as the maximum oxygen consumption [VO2 peak] on a cardiopulmonary exercise test) of…
- Trial name
- M&M's (NCT05838235)
- Testing
- Adapted Physical Activity program
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Peri-implant Bone Healing and Osseointegration
Kaempferol Gel , Alkaline Phosphatase Activity , Bone Density Around Dental Implants
Kaempferol gel was tested as a local adjunct during implant placement in 30 patients. Compared to controls, the Kaempferol group showed significantly higher ALP activity at 2 and 4 weeks and greater bone density gain after 6…
- Trial name
- NCT07156799
- Testing
- Kaempferol Gel
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Bone Loss
A Prospective Study of Human Bone Adaptation Using a Novel in Vivo Loading Model
The purpose of this study is to understand how different types of mechanical forces can influence bone adaptation (and make bones stronger, potentially). Forces acting on bones cause mechanical strain.
- Trial name
- NCT04135196
- Testing
- voluntary forearm loading task
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Worcester Polytechnic Institute
Aging
Long-life Endurance Exercise and Healthy Aging
The project aims to explore the mechanisms by which lifelong exercise can promote healthy aging and slow down the negative impact of aging on the muscular system, immunity and the circadian system.
- Trial name
- CAA (NCT05053282)
- Testing
- endurance running exercise
- Where
- Slovakia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Comenius University
Marfan Syndrome
Marfan Syndrome Moderate Exercise Trial II
Marfan syndrome (MFS) is a distinctive connective tissue disorder that affects multiple organ systems including the heart, bones, ligaments, and eyes, and is associated with significant risk of aortic dissection.
- Trial name
- NCT05809323
- Testing
- Exercise Intervention Group, Control Group
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Baylor College of Medicine
Surgical Procedure, Unspecified, Soft Tissue Infections
Non-resorbable Membranes Versus Titanium Meshes and Resorbable Membranes
The objective of this study is to compare two surgical techniques for the treatment of the mandibular bone atrophies: Dense PTFE titanium-reinforced membranes (Group A) versus Titanium mesh covered with cross-linked collagen…
- Conditions
- Surgical Procedure, Unspecified, Soft Tissue Infections, Bone Density, Bone Loss
- Trial name
- NCT04332679
- Testing
- Group A - control group, Group B - Test group
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- GBR Academy
Cerebral Palsy
The BoDI (Bone Density Investigation) Study
Background: This study involves children with cerebral palsy, a lifelong condition caused by early damage to the developing brain.
- Trial name
- NCT06117124
- Testing
- Digital X-Ray Radiogrammetry, Quantitative Ultrasound (QUS)
- Volunteers
- 70 people
- Sponsor
- Sussex Community NHS Foundation Trust
Implant Site Reaction
Evaluation of the Effect of Osseodensefication Technique Versus Conventional Implant Drilling Technique in Implant Supported Mandibular Overdenture
The present study will be performed to : evaluate the effect of two implant placement systems )conventional method and osseodensification method) radiographically on bone density and bone height surrounding the implant by using…
- Trial name
- NCT06590753
- Testing
- osseodensification bur
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Badr University
Anorexia Nervosa, Hypothalamic Amenorrhea
Hormone Dynamics and Bone Mineral Density in Anorexia Nervosa v. Hypothalamic Amenorrhea
The purpose of this study is to determine whether the hormone dynamics in women with anorexia nervosa and hypothalamic amenorrhea is related to bone loss in those populations.
- Conditions
- Anorexia Nervosa, Hypothalamic Amenorrhea, Obesity
- Trial name
- NCT00556036
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Osteoporosis
The Forteo Alendronate Comparator Trial
The main purpose of this study is to evaluate the effects of teriparatide with those of alendronate on spine bone mineral density (BMD) and other osteoporosis factors in postmenopausal women with osteoporosis.
- Trial name
- FACT (NCT02416271)
- Testing
- Teriparatide, Alendronate, Calcium
- Where
- 20 sites in United States, Brazil and 2 more
- Volunteers
- 203 people
- Sponsor
- Eli Lilly and Company
Muscle Hypertrophy, Bone Mineral Density Loss
Combined Whey Protein and Collagen Supplementation in Resistance-Trained Men
This study tested whether taking whey protein together with collagen peptides would provide greater benefits for muscle and bone health compared to whey protein alone, collagen alone, or a placebo.
- Conditions
- Muscle Hypertrophy, Bone Mineral Density Loss, Resistance Training Adaptation
- Trial name
- NCT07171411
- Testing
- Whey Protein + Collagen, Whey Protein, Collagen Peptides
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Hypercalciuria; Idiopathic
Bone Mineral Density and Vascular Calcifications in the Population of Lithiasis Patients With Idiopathic Hypercalciuria
In industrialized countries, it is estimated that around 10% of the population suffers from nephrolithiasis (NL). Numerous recent epidemiological studies report that the prevalence and incidence of NL continue to increase, with a…
- Trial name
- NCT04770506
- Testing
- Data extraction from medical files
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Agnieszka Pozdzik
Down Syndrome
Assessment of Bone Density and Bone Turnover Markers in Patients With Down Syndrome and Comparison to the Ts65Dn Model
This study may provide information that may serve as the foundation for a larger research study to address issues regarding the causes, diagnosis, and treatment of osteoporosis in the Down syndrome patient population.
- Trial name
- NCT01148121
- Testing
- Skeletal Status Assessment of a Down Syndrome Population
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Arkansas
Coronary Artery Calcification, Coronary Artery Disease
MAP-Calcification: MicroRNAs as Potential Biomarkers for Coronary Artery Calcification
Coronary artery disease (CAD) remains the leading cause of mortality in the UK with an estimated 80,000 fatalities in 2010. Coronary artery calcification (CAC) is associated with atherosclerotic plaque burden and cardiovascular…
- Conditions
- Coronary Artery Calcification, Coronary Artery Disease, Osteoporosis, Osteopenia
- Trial name
- NCT01992848
- Testing
- Venous blood sampling, 4-day food diary, 1 week UV dosimeter
- Where
- 2 sites in United Kingdom
- Volunteers
- 45 people
- Sponsor
- University of Surrey
Bone Mineral Density, Hemophilia A
Osteoporosis and MRI Study in Hemophilia
The purpose of this study is to evaluate bone mineral density in adult subjects with hemophilia versus a comparator population without hemophilia (non-hemophilia age- and gender-matched database) by using the following diagnostic…
- Conditions
- Bone Mineral Density, Hemophilia A, Hemophilia B
- Trial name
- NCT01460147
- Testing
- DXA scan + MRI
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Baxalta now part of Shire
Pre-diabetes, Obesity
Sub-Study of the PREVIEW Study Australia
The aim of this study is to investigate possible enduring effects of a standard 2-month weight loss program on appetite regulation, bone homeostasis and muscle strength in younger and older adults, as well as the impact of…
- Trial name
- NCT02030249
- Testing
- Low calorie diet administered from 0 to 2 months, High Protein / Low Glycaemic Index, Moderate Protein / High Glycaemic Index
- Where
- 3 sites in Australia
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- University of Sydney
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