Clinical trials: Bone Mass
Sarcopenia, Hip Fractures
Sarcopenia and Bone Mineral Density Relation in Hip Fracture Patients
The study aims to investigate the relationship between sarcopenia and bone mineral density (BMD) in patients with hip fractures using sonographic thigh adjustment ratio (STAR) and dual-energy X-ray absorptiometry (DXA), as well…
- Trial name
- NCT06508957
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Kastamonu University
Postmenopausal Osteopenia, Bone Loss, Age Related
OsteoPreP: Food Supplements for Postmenopausal Bone Health
To evaluate the effect of 12 months of supplementation with a probiotic (probiotic plus prebiotic; 2 capsules per day) on relative change (%) in total volumetric bone density (measured using high resolution peripheral…
- Conditions
- Postmenopausal Osteopenia, Bone Loss, Age Related, Age-Related Sarcopenia, Glucose Metabolism Disorders
- Trial name
- OsteoPreP (NCT05348694)
- Testing
- Pendulum WBF-038
- Where
- Australia
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Australian Catholic University
Healthy
Effects of Pistachio Consumption on Body Composition and Blood and Bone Indicators
Research investigating beneficial effects of regular pistachio feedings on body composition (BC) and blood lipids are limited, and there are no studies that have investigated the effects of feeding pistachios on bone density or…
- Trial name
- CPsPistachio (NCT02849392)
- Testing
- Pistachio added 20% of kcals to diet
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- California State Polytechnic University, Pomona
Sinusitis
The Long-Term Safety of Budesonide for Patients With Chronic Rhinosinusitis
Chronic Rhinosinusitis (CRS) is a common disorder of the nose. The current practice at St Paul's Sinus Centre is to prescribe budesonide via the mucosal atomization device or impregnated saline irrigation.
- Trial name
- NCT03584178
- Testing
- Budesonide via MAD device, Budesonide via intranasals Saline Irrigation
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- St. Paul's Hospital, Canada
Marfan Syndrome
The Oxford Marfan Trial
The primary objective of the trial is to estimate the effects of allocation to irbesartan, or doxycycline, or a combination of both irbesartan and doxycycline, compared with placebo, on measures of elastic function of the aorta…
- Trial name
- NCT01949233
- Testing
- Irbesartan 150-300mg capsules daily for 6 months, Doxycycline 100-200mg capsules daily for 6 months
- Where
- 2 sites in United Kingdom
- Volunteers
- 56 people
- Sponsor
- University of Oxford
Anorexia Nervosa, Interruption of Growth
Severe Decrease of Growth Velocity in Children With Anorexia Nervosa.Therapeutic Trial of Growth Hormone
Anorexia nervosa may be responsible for a catch- down or even an interruption of growth, delayed puberty and osteopenia with failure of acquisition of bone mass.
- Conditions
- Anorexia Nervosa, Interruption of Growth, Delayed Puberty, Osteopenia With Failure of Acquisition of Bone Mass
- Trial name
- OREX (NCT01626833)
- Testing
- SOMATROPINE* : Norditropine® simplexx®
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hip Arthroplasty
Stem Cells Predicting Orthopedic Outcomes
This is a pilot study to provide preliminary data of the association between bone mineral denity adjacent to acetabular implants, as measured by quanitative computed tomography (QCT), at least 2 years post Total Hip Arthoplasty…
- Trial name
- NCT01366911
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Parkinson's Disease
Study of Factors Associated With the Volumetric and Areal Bone Mineral Density and Bone Strength in Parkinson's Disease
Studies show that patients with idiopathic Parkinson's disease (IPD) have an increased risk of fracture, particularly hip fracture whose complications and postoperative mortality appear to be higher than in the general…
- Trial name
- PAFOS (NCT02930512)
- Testing
- DXA scan, pQCT scan
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Clermont-Ferrand
Osteoporosis Fracture, Spinal Cord Injuries
Evaluation of Romosozumab vs. Zoledronic Acid Effect in Patients With Spinal Cord Injury and Low Bone Mineral Density
This is a randomized study to determine the effects of monthly romosozumab for one year or one-time zoledronic acid on bone mineral density (BMD) and biochemical markers of bone formation and resorption, in patients with spinal…
- Trial name
- NCT04597931
- Testing
- Romosozumab, Zoledronic Acid
- Volunteers
- 30 people
- Sponsor
- Sheba Medical Center
Osteoporosis
RCT: Added Value of Coordinator for the Management of Hip Fracture Patients
Introduction: Hip fracture due to osteoporosis is associated with an extremely high mortality morbidity and loss of quality of life. The risk of future fracture after a first hip fracture is increased.
- Trial name
- NCT01785381
- Testing
- Added value of coordinator
- Where
- Belgium
- Volunteers
- 128 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Osteoporosis
Study to Evaluate Efficacy of Odanacatib (MK-0822) on Bone Mineral Density (BMD) and Bone Micro-architecture and Overall Safety in Postmenopausal Women (MK-0822-031)
This study will evaluate the safety and treatment effect of 50 mg odanacatib (MK-0822) with Vitamin D versus placebo with Vitamin D in postmenopausal women with low bone density.
- Trial name
- NCT00729183
- Testing
- Odanacatib, Vitamin D3, Calcium supplement
- Volunteers
- 214 people
- Sponsor
- Merck Sharp & Dohme LLC
OSTEOPOROSIS, POSTMENOPAUSAL
Risedronate in Postmenopausal Women With Low Bone Density
The primary objective of this pilot study is to estimate the percent change from baseline at Week 4, Month 6 in NTX bone turnover marker for a monthly 150mg dose of risedronate administered for 6 months and a loading dose regimen…
- Trial name
- NCT00351091
- Testing
- RISEDRONATE
- Volunteers
- 150 people
- Sponsor
- Sanofi
Osteoporosis
A Randomized Controlled Trial of a Bone Density Decision Aide
This research study is being conducted to determine if a modified bone mineral density (BMD) test report that contains additional fracture risk information will be a useful physician decision aide in selecting patients for…
- Trial name
- NCT00285168
- Testing
- Bone Density Decision Aide
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Manitoba
Hematologic Diseases, Acute Myeloid Leukemia
Muscle Dysfunction in Patients With Haematological Diseases
PURPOSE: To evaluate the prevalence and prognostic value of sarcopenia in patients diagnosed with hematological cancer diseases.
- Conditions
- Hematologic Diseases, Acute Myeloid Leukemia, Acute Lymphoid Leukemia, Myelodysplastic Syndromes
- Trial name
- NCT05150561
- Where
- Denmark
- Volunteers
- 216 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Osteonecrosis, Femoral Neck Fracture
A Comparison of Two Different Surgical Techniques in Hip Resurfacing Arthroplasty
The purpose of the study is to compare two different surgical techniques in hip resurfacing arthroplasty (RHA), comparing bloodflow and metabolism in the femoral head, as well as implant migration, periprosthetic bone mineral…
- Conditions
- Osteonecrosis, Femoral Neck Fracture, Implant Failure
- Trial name
- NCT00913679
- Testing
- Surgical approach (ReCap Hip Resurfacing System)
- Where
- Denmark
- Volunteers
- 49 people
- Sponsor
- University of Aarhus
Ulcerative Colitis, Crohn's Disease
Nasal Calcitonin in the Treatment of Bone Mineral Loss in Children and Adolescents With Inflammatory Bowel Disease
The hypothesis underlying this study is that nasally administered calcitonin will stabilize or improve bone mineral density in young patients with ulcerative colitis or Crohn's disease.
- Trial name
- NCT00114803
- Testing
- Calcitonin nasal spray (salmon)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Boston Children's Hospital
Left Ventricular Dysfunction
Use of Adult Autologous Stem Cells in Treating People 2 to 3 Weeks After Having a Heart Attack (The Late TIME Study)
More than 1 million Americans suffer heart attacks each year. Although current treatments are able to stabilize the condition of the heart, none is able to restore heart function as it was prior to the heart attack.
- Trial name
- NCT00684060
- Testing
- Adult stem cells
- Where
- 5 sites in United States
- Volunteers
- 87 people
- Sponsor
- The University of Texas Health Science Center, Houston
Weight Gain, Disorder of Bone Density and Structure, Unspecified
Drug Exposure and Depot Medroxyprogesterone Acetate (DMPA) in Adolescent Subjects
The investigators are doing this study to look at how different doses of the Depot medroxyprogesterone acetate (DMPA) shot effect weight gain and bone mineral density in teens.
- Conditions
- Weight Gain, Disorder of Bone Density and Structure, Unspecified, Uterine Bleeding
- Trial name
- NCT01461824
- Testing
- Depot medroxyprogesterone acetate (DMPA)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Nationwide Children's Hospital
Osteoporosis, Prostate Cancer
Bone Mineral Density and Cancer Recurrence in Patients With Early Stage Prostate Cancer
RATIONALE: Measuring bone mineral density may help doctors predict whether prostate cancer will come back. It may also help the study of prostate cancer in the future.
- Trial name
- NCT00176579
- Testing
- dual x-ray absorptiometry
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Osteopenia, Postmenopausal Osteopenia
Effect of Calcium and Vitamin D Supplementation With and Without Collagen Peptides in Postmenopausal Women With Osteopenia
Osteoporosis is undoubtedly one of the most common diseases affecting older individuals with debilitating consequences. Osteopenia, defined as T-score between -1 and -2.5, has also been associated with increased risk of…
- Trial name
- NCT03999775
- Testing
- Calcium, vitamin D and bioactive collagen peptides supplement, Calcium and vitamin D supplement
- Volunteers
- 51 people
- Sponsor
- Ioannis K. Triantafyllopoulos, MD,MSci,PhD
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