Clinical trials: Bone Microarchitecture
Stroke, Hemiplegia
Impact of Hemiplegia Due to Stroke on the Microarchitecture of the Bone
In hemiplegic, there is very little data on the impact of neurological deficit on the microarchitecture independent of bone mineral density and composition of the bone marrow.
- Trial name
- NCT02544386
- Testing
- MRI and 3D CT scan
- Volunteers
- 10 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Arthritis, Rheumatoid
Bone MicroArchitecture Abatacept (BMA2)
Rheumatoid Arthritis patients management reposes primarily on the use of disease-modifying antirheumatic drugs (DMARDs). Among DMARDs available in 2015, researchers demonstrated the ability to reduce synovitis, biomarkers of…
- Trial name
- BMA2 (NCT02675218)
- Testing
- Patients with rheumatoid arthritis
- Where
- 5 sites in France
- Volunteers
- 13 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Bone Regeneration
Teriparatide on Maxillary Sinus Floor Osseointegration
The aim of this triple blind randomized controlled trial will be to analyze the effect of a dose of teriparatide combined with a xenograft on bone augmentation of the maxillary sinus, to observe the microarchitecture of the newly…
- Trial name
- NCT06061354
- Testing
- Teriparatide, Maxillary Sinus Augmentation, Dental Implant Installation
- Where
- Chile
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Universidad de Valparaiso
Severe Hemophilia A, Osteoporosis
Bone Microarchitecture in Men With Hemophilia
Hemophilia A and B are hereditary sex-linked deficiencies of coagulation factors VIII and IX characterized by bleeding. Their modern therapy increases life expectancy and risk of age-related diseases, e.g., osteoporosis.
- Trial name
- HEMOS (NCT05127681)
- Testing
- HR-pQCT, Blood sample, Dual energy X-ray absorptiometry
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Hospices Civils de Lyon
Type 1 Diabetes Mellitus
Microarchitecture, Bone Strength and Fracture Risk in Long-term Type 1 Diabetes
This single center case control study will assess differences in bone structure between women and men with longstanding type 1 diabetes (diabetes duration>/= 25 years) and healthy controls.
- Trial name
- BOLD-1 (NCT03751839)
- Testing
- Biochemical Tests, Osteodensitometry, Clinical Tests
- Where
- Switzerland
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Christian Meier
Organ Transplant
Bone Microarchitecture in the Transplant Patient
The optimal management of calcium and phosphate metabolism regulation in chronic kidney disease (CKD) is important in preventing fracture risk and vascular calcification and thus morbidity and mortality, global and vascular.
- Trial name
- TRANSOS (NCT02729142)
- Testing
- Tibial cortical density evaluation
- Where
- 3 sites in France
- Volunteers
- 137 people
- Sponsor
- Hospices Civils de Lyon
Rheumatoid Arthritis
RA Denosumab on Bone Microstructure Study
The aim of this study is to compare the effects of denosumab and a current standard treatment on cortical and trabecular microarchitecture at the radius and second metacarpal in rheumatoid arthritis (RA) patients with low bone…
- Trial name
- NCT01770106
- Testing
- Denosumab, Alendronate
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Chinese University of Hong Kong
Bone Fragility
Mother Daughter Bone Microarchitecture
The aim of this study is to analyze the hereditary determinism of bone microarchitecture measured at the distal radius and distal tibia from a case control-study of mother-daughter pairs.
- Trial name
- MODAM (NCT01258036)
- Testing
- HRpQCT, Sampling, Bone absorptiometry
- Where
- France
- Volunteers
- 1,040 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
HIV Infection, Alcohol Use
Boston Alcohol Research Collaboration on HIV/AIDS (ARCH) Cohort
The purpose of this study is to expand and continue a cohort of HIV-infected adults to establish the longitudinal Boston ARCH Cohort of 250 HIV-infected men and women with current substance dependence or ever injection drug use…
- Conditions
- HIV Infection, Alcohol Use, Bone Disease, Substance-Related Disorders
- Trial name
- NCT01740115
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Boston Medical Center
Cone Beam Computed Tomography, Periodontitis
Evaluation of the Effects of Smoking on Trabecular Bone Microarchitecture Using CBCT in Periodontal Disease
The purpose of this cross-sectional study is to evaluate the morphometric properties of trabecular bone quality using Cone-beam computed tomography in periodontal disease at different stages, comparing smokers and non-smokers.
- Conditions
- Cone Beam Computed Tomography, Periodontitis, Diagnosis of Bone Quality, Diagnosis, Oral
- Trial name
- NCT06676358
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Okan University
Postmenopausal Osteoporosis
Study of Bone Histomorphometry, Microarchitecture, and Matrix Structure in Patients Receiving Alendronate or Risedronate
Patients who have received the appropriate number of years of alendronate or risedronate therapy will be recruited. Each patient will have received baseline BMD measurements performed at the spine and the hip by DXA.
- Trial name
- NCT00778154
- Where
- 8 sites in United States, Canada
- Volunteers
- 105 people
- Sponsor
- Warner Chilcott
Osteoporosis, Postmenopause
The Effect of Mechanical Loading on Bone Material Strength and Microarchitecture in Postmenopausal Women
Osteoporosis is a large public health disease, characterized by low bone mass and micro architectural deterioration of bone tissue, resulting in enhanced bone fragility and consequent increase in fracture risk.
- Trial name
- NCT02339051
- Testing
- Jumping on one leg
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mattias Lorentzon
Bone Microarchitecture
Bone Microarchitecture in Women Practicing Golf
After the age of 50, one in three women and one in eight men will experience at least one fragility fracture during the rest of their lives.
- Trial name
- NCT02544399
- Testing
- 3D CT scan
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne