Clinical trials: Bone Pain
Postoperative Pain
Evaluation of PENG Block in Terms of Block Time and Postoperative Pain
Hip fracture is a common orthopedic emergency in the elderly and causes significant morbidity and is associated with mortality. In most patients, surgical reduction and fixation is the definitive treatment.
- Trial name
- NCT06132308
- Testing
- PENG Block with 0.25% bupivacaine
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Distal Radius Fracture, Chronic Regional Pain Syndrome
Effectiveness of Virtual Reality in Hand Therapy
The purpose of this study is to determine if the use of Virtual Reality as an intervention for patients following specific hand injuries will positively affect patients with decreased hand function and reduce pain and improve…
- Conditions
- Distal Radius Fracture, Chronic Regional Pain Syndrome, Flexor Tendon Rupture
- Trial name
- NCT05188040
- Testing
- Virtual Reality Exercises
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Timothy Uhl
Refractory Angina
Intramyocardial Delivery of Autologous Bone Marrow
A randomized study to assess the safety, feasibility and effectiveness of direct intramyocardial percutaneous delivery of autologous bone marrow-derived total mononuclear cells or selected CD34+ cells in patients with refractory…
- Trial name
- NCT00820586
- Testing
- Mononuclear bone marrow derived cells
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- IRCCS San Raffaele
Low Back Pain, Spondylolysis
Feasibility of Using Functional Progression to Guide the Treatment of Adolescent Low Back Pain
The goal of the proposed research is to test the feasibility of a functional progression program to reduce cost and possible radiation exposure for adolescent athletes with low back pain.
- Conditions
- Low Back Pain, Spondylolysis, Spondylolisthesis
- Trial name
- NCT02861456
- Testing
- Standard Model of Care, Alternative Model of Care
- Where
- 4 sites in United States
- Volunteers
- 16 people
- Sponsor
- Nationwide Children's Hospital
Painful Bone Metastases, Breast Carcinoma
MRI Guided High Intensity Focused Ultrasound (HIFU) and ThermoDox for Palliation of Painful Bone Metastases
This study will evaluate treatment with High Intensity Focused Ultrasound (HIFU)in combination with ThermoDox (liposomal doxorubicin) is safe and effective in reducing pain for patients with painful bone metastases.
- Conditions
- Painful Bone Metastases, Breast Carcinoma, Non-small Cell Lung Cancer, Small Cell Lung Cancer
- Trial name
- NCT01640847
- Testing
- High Intensity Focused Ultrasound (HIFU) in combination with ThermoDox
- Sponsor
- Imunon
ACL Reconstruction (ACLR) With a Bone-patellar Tendon-bone (BPTB) Autograft
Cryoneurolysis in Anterior Cruciate Ligament Reconstruction (ACLR)
The purpose of this research study is to assess whether cryoneurolysis will help control pain after ACLR surgery and decrease the need of opioid medications.
- Trial name
- NCT07731178
- Testing
- Pacira Iovera Cryoneurolysis device
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health
Acute Distal Radius Fracture, Displaced Distal Radius Fracture
Nerve and Hematoma Blocks for Pain Relief During Distal Radius Fracture Reduction
Distal radius fractures, commonly known as wrist fractures, are among the most frequent injuries seen in emergency departments. These injuries often require a closed reduction, a procedure in which the broken bone is manipulated…
- Trial name
- BRAVE (NCT07183904)
- Testing
- Hematoma Block, Median Nerve Block
- Where
- Spain
- Volunteers
- 180 people
- Sponsor
- Hospital Universitario 12 de Octubre
Psoriatic Arthritis, Enthesitis
Immune-Competent Cell Manifestations in Psoriatic Arthritis Achilles Tendons
Tendon pathologies (enthesitis) are a characteristic component of psoriatic arthritis (PsA), and are observed in 35% to 50% of PsA patients. The Achilles tendon is one of the most commonly affected sites.
- Trial name
- IMPAACT (NCT03248284)
- Testing
- Tendon biopsy procedure
- Where
- 2 sites in Denmark
- Volunteers
- 30 people
- Sponsor
- Odense University Hospital
Traumatic Rib Fracture(s), Traumatic Rib Fracture
Erector Spinae Plane vs Serratus Anterior Plane Catheter Infusions for Acute Pain Management in Patients With Traumatic Rib Fractures
Rib fractures happen in about 10-20% of patients with blunt trauma and can be serious, with higher death rates in older adults. These injuries often lead to lung problems like pneumonia, collapsed lung areas (atelectasis), fluid…
- Trial name
- NCT07756047
- Testing
- Erector spinae plane catheter, Serratus plane catheter
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- Sunnybrook Health Sciences Centre
Procedural Pain, Anxiety
Effect of Stress Ball Use on Pain, Anxiety, and Vital Signs During Ultrasound-Guided Tru-cut Biopsy
This randomized controlled trial aims to evaluate the effect of stress ball application on pain, anxiety, and vital signs in adult patients undergoing ultrasound-guided tru-cut biopsy procedures.
- Conditions
- Procedural Pain, Anxiety, Tru-Cut Biopsy, Stress Response
- Trial name
- STRESS-BX (NCT07613736)
- Testing
- Behavioral: Stress Ball Application
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people
- Sponsor
- Istanbul University
Sciatica, Intervertebral Disc Displacement
Effects of Shinbaro Pharmacopuncture in Sciatic Pain Patients With Lumbar Disc Herniation
This trial will evaluate the comparative clinical effectiveness of pharmacopuncture for severe non-acute sciatic pain patients diagnosed with lumbar disc herniation (LDH) with usual care of conventional medicine and that of…
- Trial name
- NCT02384928
- Testing
- Shinbaro pharmacopuncture, Acupuncture, Conventional medicine
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Jaseng Medical Foundation
Degenerative Spondylolisthesis
Multimodal Perioperative Pain Management
Convalescence after lumbar fusion is dependent on pain. In orthopaedic and abdominal surgery accelerated stay programs with optimized pain management enhance recovery.
- Trial name
- NCT01513564
- Testing
- Postoperative epidural morphine, Local anaesthesia
- Where
- Denmark
- Volunteers
- 120 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Advanced Cancer
Pain Management Support Study for Patients With Advanced Cancer
Chronic pain is one of the most feared symptoms in people with cancer. Insufficient relief from pharmacological treatments and the fear of side effects are important reasons for the growing use of complementary pain management…
- Trial name
- NCT03432247
- Testing
- Interactive Music Therapy, Verbal support
- Where
- 3 sites in United States
- Volunteers
- 103 people
- Sponsor
- Drexel University
Knee Pain
Anterior Knee Pain After Tibial Nailing
Anterior knee pain (AKP) is a common complication following intramedullary (IM) nailing of a tibial shaft fracture. The purpose of this prospective study was to determine if there is an association between AKP and nail position.
- Trial name
- NCT01106963
- Testing
- Tibial intramedullary nailing
- Where
- Croatia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Zagreb
Juvenile Osteochondrosis of Spine
Sling Suspension Versus Gym Balls in the Treatment of Juvenile Spinal Osteochondrosis
This study compares effect of swiss ball exercises with sling suspension exercises in the treatment of juvenile osteochondrosis in adolescent-girls
- Trial name
- NCT03851367
- Testing
- Sling suspension using red cord, Gym ball exercises
- Where
- Lithuania
- Volunteers
- 40 people
- Sponsor
- Lithuanian Sports University
Lumbar Spinal Stenosis
EuroPainClinics® Study II (Prospective Trial)
In this prospective multi-centre double-blind trial the effect of the epiduroscopy will be examined in (approximately 300) adult patients with low back pain pain caused by failed back surgery syndrome (FBSS).
- Trial name
- EPCSII (NCT02459392)
- Testing
- Epiduroscopy, Hyaluronic Acid, DepoMedrol
- Where
- Czechia
- Volunteers
- 300 people
- Sponsor
- EPC Education s.r.o.
Failed Moderate Sedation During Procedure
Effects of Dexmedetomidine on the Postoperative Experience in Children
Background: The study aim was to compare the efficacy of dexmedetomidine versus midazolam for sedation during the early postoperative period in children who underwent scoliosis surgery.
- Trial name
- NCT01748630
- Testing
- dexmedetomidine, Midazolam, fentanyl
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Inonu University
Lumbar Disc Herniation
Barricaid EU Post Market Study for Primary Lumbar Disc Herniation
The purpose of this multi-center post marketing surveillance study is to monitor the safety and performance of the Barricaid® ARD when used to surgically reconstruct the anulus of the L1 - S1 spinal disc.
- Trial name
- NCT01534065
- Testing
- Barricaid
- Volunteers
- 45 people
- Sponsor
- Intrinsic Therapeutics
Ankle Fractures, Syndesmotic Injuries
Effects of Postoperative Kinesio Taping in Weber Type B Lateral Malleolar Fractures
This randomized controlled trial aimed to evaluate the effects of postoperative Kinesio taping on pain, range of motion, and edema in patients undergoing surgical fixation for Weber type B lateral malleolar fractures.
- Conditions
- Ankle Fractures, Syndesmotic Injuries, Postoperative Rehabilitation
- Trial name
- KT-WeberB (NCT06958133)
- Testing
- Standard Postoperative Rehabilitation, Kinesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Degenerative Disc Disease
Viable Allograft Supplemented Disc Regeneration in the Treatment of Patients With Low Back Pain
The objective of this study is to evaluate the safety and efficacy of viable allograft transplantation for the treatment of patients with symptomatic disc degeneration and tissue loss.
- Trial name
- VAST (NCT03709901)
- Testing
- Active Allograft
- Where
- 13 sites in United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- VIVEX Biologics, Inc.
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