Clinical trials: Bone Pain
Osteoporotic Fractures
Vertebroplasty Compared With a Sham-procedure for Painful Acute Osteoporotic Vertebral Fractures
The main purpose of this study: to determine whether vertebroplasty has a pain palliating effect superior to a sham-procedure for acute painful osteoporotic vertebral fractures of the thoracic and lumbar spine.
- Trial name
- VOPE (NCT01537770)
- Testing
- Percutaneous vertebroplasty, Lidocaine injection
- Where
- Denmark
- Volunteers
- 52 people
- Sponsor
- Spine Centre of Southern Denmark
Postoperative Pain, Spine Deformity
Intraoperative Placement of Superficial Erector Spinae Plane Block; A New Approach in Spine Surgery
Major spine surgery causes severe postoperative pain. The primary objective of this randomized controlled study is to compare the effect of ultrasound (US)-guided superficial erector spinae plane (ESP) block on 48-hour…
- Conditions
- Postoperative Pain, Spine Deformity, Spine Injury, Spine Fracture
- Trial name
- NCT05244031
- Testing
- superficial erector spina plane block, Standard (opioid-based) analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Distal Radius Fracture, Pain
Effectiveness of Graded Motor Imagery to Improve Hand Function in Patients With Distal Radius Fracture
The purpose of this study was to investigate of the effectiveness of Graded Motor Imagery (GMI) on hand functionality in patients with Distal Radius Fracture (DRFx). This study was carried out on 36 patients.
- Trial name
- NCT02838446
- Testing
- Cognitive Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Hacettepe University
Rheumatoid Arthritis, Healthy Control
Adipokines as Predictors of Foot Function, Pain, and Disability in Patients With Rheumatoid Arthritis
Significant increase in the levels of serum adiponectin, ADA, and hsCRP was reported in all RA patients compared to controls. Compared to patients with early RA, the increase in these markers significantly correlated with disease…
- Trial name
- NCT04036669
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- King Saud University
Cancer
Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain
RATIONALE: Ketamine hydrochloride may lessen neuropathic pain in patients with cancer. It is not yet known whether ketamine hydrochloride given together with the best pain management is more effective than a placebo given…
- Trial name
- NCT01316744
- Testing
- ketamine hydrochloride, pharmacogenomic studies, questionnaire administration
- Where
- 3 sites in United Kingdom
- Volunteers
- 214 people
- Sponsor
- University of Glasgow
Bone Marrow Aspiration and Biopsy, Pain
Fake Coughing During Bone Marrow Aspiration and Biopsy
Hematology patients go through many difficult periods during the diagnosis process. One of the most commonly used methods in the diagnosis of hematological diseases is bone marrow aspiration and biopsy (BMAB).
- Conditions
- Bone Marrow Aspiration and Biopsy, Pain, Feigned Cough, Stress Ball
- Trial name
- NCT07063498
- Testing
- Coughing Maneuver, Stress ball
- Volunteers
- 80 people
- Sponsor
- Firat University
Degenerative Disc Disease
Autologous, Culture-Expanded Mesenchymal Stromal Cells for Degenerative Disc Disease
To determine the safety and feasibility of autologous, culture-expanded adipose-derived (AD) mesenchymal stromal cells (MSCs) in subjects with painful degenerative disc disease (DDD).
- Trial name
- NCT03461458
- Testing
- Autologous Adipose-Derived Mesenchymal Stromal Cells
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Knee Arthritis, Osteoarthritis, Bone Marrow Edema of the Knee
Extracorporeal Shock Wave Therapy in the Treatment of Periarticular Bone Marrow Edema in Patients With Knee Osteoarthritis
Bone marrow edema (BME) is a radiological finding characterized by increased fluid content and structural changes within the bone marrow. It most commonly affects weight-bearing joints such as the hip, knee, and ankle.
- Conditions
- Knee Arthritis, Osteoarthritis, Bone Marrow Edema of the Knee, Bone Marrow Edema
- Trial name
- NCT07887893
- Testing
- Radial Extracorporeal Shock Wave Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Humeral Fractures, Fractures, Closed
Pain Management in Children Undergoing Supracondylar Humerus Fracture Repair
The purpose of this study is to determine if US-guided supraclavicular anesthetic blocks reduce postoperative pain, use of rescue medication, and improve functional outcomes in children who underwent surgery for supracondylar…
- Trial name
- NCT01812863
- Testing
- Supraclavicular nerve block
- Where
- United States
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Apical Periodontitis, Endodontically Treated Teeth
Effect of Photobiomodulation on Pain and Healing of the Vertical Releasing Incision After Endodontic Microsurgery
The purpose of this study is to evaluate the effect of Photobiomodulation (PBM) in postoperative pain after endodontic microsurgery (EMS) in patients from the University of Texas Health Science Center at Houston, School of…
- Conditions
- Apical Periodontitis, Endodontically Treated Teeth, Endodontic Disease, Apical Cyst
- Trial name
- NCT06574152
- Testing
- PBM treatment, EMS
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pain, Acute, Postoperative Pain
PENG Block With Two Diffirent Volume
Hip fractures are morbid conditions, especially in elderly patients, and their treatment is usually surgical. Pericapsular nerve group block is a newly defined block and targets the hip capsule.
- Conditions
- Pain, Acute, Postoperative Pain, Hip Fractures
- Trial name
- NCT05358587
- Testing
- Ultrasound guided PENG block with 20 mL Local Anesthetic solution, Ultrasound guided PENG block with 30 mL Local Anesthetic solution
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Samsun University
Arthralgia, Trouble Balancing
Even-Up to Minimize Secondary Site Pain For Ankle Fracture
Evaluating impact of use of Even-Up shoe wear device for patients treated in CAM boot walker for an ankle fracture. Randomized controlled trial, randomizing patients into control group with boot treatment only versus boot…
- Trial name
- NCT04164563
- Testing
- Even-Up
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Chronic Myeloproliferative Disorders, Leukemia
Treatment for Chronic Pain in Patients With Advanced Cancer
RATIONALE: Different drug formulations and combinations of drugs may help patients with chronic pain live more comfortably. It is not yet known which regimen is most effective for chronic pain.
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00003687
- Testing
- dextromethorphan hydrobromide, morphine sulfate
- Where
- 4 sites in Canada
- Volunteers
- 87 people
- Sponsor
- NCIC Clinical Trials Group
Cancer, Spinal Disease
Anderson Circulating Tumor Cell Burden (CTCB) Study
Phase 1 - Optimization Phase: Primary Objective: The primary objective of Phase 1 of this study is to determine the time point at which maximal Circulating Tumor Cell Burden (CTCB) occurs following standard vertebroplasty and…
- Conditions
- Cancer, Spinal Disease, Vertebral Compression Fractures
- Trial name
- NCT00819832
- Testing
- Kyphoplasty, Vertebroplasty, Cavity SpineWand
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- M.D. Anderson Cancer Center
Pain, Postoperative, Excavatum, Pectus
Comprehensive Study of Post-surgical Pain After Pectus or Spine Surgery
This will be a prospective observational study to determine the association between specific genotypes, epigenetics, behavioral, social and biological factors, with the phenotypes, defined by pain perception, postoperative pain…
- Conditions
- Pain, Postoperative, Excavatum, Pectus, Scoliosis Idiopathic
- Trial name
- NCT04031716
- Testing
- Meditation
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Analgesia, Postoperative Pain
The Comparison of Analgesia Methods Used for Spinal Surgery
In this study ; Two randomized groups will be created. Iv magnesium will be given to one of the blindly designated groups. The other group will be given only isotonic.
- Trial name
- NCT04603638
- Testing
- Magnesium, Isotonic
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Istanbul University
Postoperative Pain, Lumbar Disc Surgery
Efficacy and Safety of Ultrasound-guided Lateral Thoracolumbar Interfascial Plane Block (TLIPB) for Postoperative Pain in Patients Undergoing Herniated Lumbar Disc Surgery
Surgery of the lumbar spine is characterized by diffuse and severe postoperative pain. In recent years, some case reports indicate that the thoracolumbar interfascial plane block (TLIPB) can reduce postoperative pain after spinal…
- Trial name
- NCT03951038
- Testing
- PCIA group, Lateral TLIPB group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Acute Lumbar Sciatica Secondary to Disc Herniation
High Versus Low Level of Lumbar Traction in Acute Lumbar Sciatica Due to Disc Herniation
The aim of this study is to compare two levels (high and low forces) of short term lumbar traction on pain and functional tests of the lower limbs in a specific population of patients presenting with acute lumbar sciatica…
- Trial name
- NCT02091791
- Testing
- Traction sessions
- Where
- France
- Volunteers
- 17 people
- Sponsor
- University Hospital, Strasbourg, France
Distal Radius Fractures
Treatment of Distal Radius Fractures in Elderly Patients
The purpose of this study is to create and test a treatment algorithm to guide the treatment of distal radius fractures in patients 65 and older and to obtain level-one evidence to determine the best method of treating distal…
- Trial name
- NCT00788190
- Testing
- Distal Radius Fracture Reduction, Conservative Management
- Where
- 2 sites in Canada
- Volunteers
- 65 people
- Sponsor
- Hand and Upper Limb Clinic, Canada
Chronic Pain, Spine Disease
An Observational Study of Integrated Chronic Pain Management in a Community Health Center
This was a prospective observational study with the primary objective of quantifying a change in pain scores after 6-12 months of two separate interventions within the study site (pain team and chiropractic team).
- Trial name
- NCT04490291
- Testing
- chronic pain team, chiropractic team
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
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