Clinical trials: Bone Pain
Pubic Symphysis Diastasis
Effects of Pelvic Floor Exercises and Pelvic Support Belt in Symphysis Pubis Dysfunction
Symphysis Pubis Dysfunction (SPD) is a medical condition that affects the pelvic region, particularly the joint that joins the two pubic bones at the front of the pelvis, the pubic symphysis.
- Trial name
- NCT07440862
- Testing
- pelvic floor excercises, pelvic support belt
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Bone Metastasis
Antalgic Treatment of Painful Bone Metastases by US-guided High Intensity Focused Ultrasound (HIFU)
Antalgic treatment of painful bone metastases by US-guided High Intensity Focused Ultrasound (HIFU).
- Trial name
- NCT01765907
- Testing
- HIFU
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Theraclion
Cancer Pain
Predictive Factors of Analgesic Response in Patients With Pain Associated With Bone Metastasys
The study aims to improve the knowledge of pain associated with bone metastases, in particular to analyze the clinical course of patients who are affected by pain due to bone metastases, in order to better understand which…
- Trial name
- CIBP (NCT06777004)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Malleolus Fracture, Lateral
Comparing Function, Pain and Return to Work in Conservative Versus Surgical Treated Stable Lateral Malleolar Fractures
Ankle fractures are one of the most common fractures in adults resulting in hospital stays and inability to work. Instable or dislocated ankle fractures are mostly treated by surgery.
- Trial name
- NCT03587571
- Testing
- Surgical intervention
- Where
- Switzerland
- Volunteers
- 3 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Thoracic Injuries, Rib Fractures
Serratus Plane Block With Parenteral Opioid Analgesia Versus Patient Controlled Analgesia in Rib Fractures
In this multicentre randomised controlled trial, adult patients with isolated chest trauma and two or more unilateral rib fractures will be randomised to either serratus plane block and patient controlled analgesia or patient…
- Conditions
- Thoracic Injuries, Rib Fractures, Anaesthesia, Local, Levobupivacaine
- Trial name
- COPE (NCT03919916)
- Testing
- Serratus plane block, Patient controlled analgesia
- Where
- United Kingdom
- Volunteers
- 58 people
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Impacted Mandibular Third Molar
The Effect of Topical Application of Hyaluronic Acid and Melatonin Mixture Following Surgical Extraction of Impacted Mandibular Third Molars .
This randomized controlled clinical trial aims to evaluate the clinical and radiographical effects of the application of a mixture of hyaluronic acid and melatonin after surgical extraction of impacted mandibular third molars.
- Trial name
- NCT07735806
- Testing
- Hyaluronic acid and Melatonin mixture, Gel foam
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kafrelsheikh University
Rib Fractures, Pain, Acute
Dexmedotomidine for Acute Pain Control in Patients With Multiple Rib FracturesRandomized Controlled Trial
Blunt chest trauma is the second most common form of unintentional trauma in the US and is associated with significant morbidity and mortality. Thoracic injuries are the third most common cause of death in trauma patients.
- Trial name
- NCT05321121
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of California, Irvine
Postoperative Pain, Mandible Fracture
Postoperative Pain After Bupivacaine Supplementation in Mandibular Fracture Surgery
Pain following open reduction of mandibular fractures is the most reported complaint during the first 24 post-operative hours. The goal of this clinical trial is to evaluate the impact of inferior alveolar nerve block with…
- Conditions
- Postoperative Pain, Mandible Fracture, Analgesia, Anesthesia, Local
- Trial name
- NCT06243263
- Testing
- Bupivacain
- Where
- 2 sites in Tunisia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Tunis El Manar
Rib Fractures, Pain, Acute
A Retrospective Review of Rib Fracture Pain Management at a London Major Trauma Centre
Thoracic epidural analgesia (TEA) is widely considered to be the current gold standard treatment for rib fracture pain and is used in the Imperial invasive treatment pathway for rib fractures.
- Trial name
- NCT04863807
- Testing
- Regional Anaesthesia
- Where
- United Kingdom
- Volunteers
- 389 people
- Sponsor
- Imperial College Healthcare NHS Trust
Femoral Fractures
Comparison of Spinal Anesthesia and Erector Spinae Plane Block in Critically Adult Patients Undergoing Femur Surgery
The goal of this observational study is to compare the regional anesthetic methods (not including general anesthesia) -spinal anesthesia, erector spinae plane (ESP) block- which are in routine practice in critically ill adult…
- Trial name
- NCT06652334
- Testing
- Spinal anesthesia, Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Duzce University
Degenerative Disc Disease
Brain Imaging of Pain-Related Processing and Structural Properties in Disc Degenerative Disease
In this study, we apply brain MR imaging techniques at 3 Tesla to assess pain-relevant processing in patients with disc degenerative disease (DDD) scheduled for back surgery and age- and gender-matched controls without back pain.
- Trial name
- POADOSpre (NCT04934917)
- Testing
- Magnetic Resonance Imaging
- Where
- 2 sites in Sweden
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Pain
Does Trans-Cutaneous Electrical Nerve Stimulation (TENS) Alleviate The Pain Experienced During Bone Marrow Sampling?
The approach of this study will be to answer the question does high-frequency stimulation Trans-Cutaneous Electrical Nerve Stimulation (TENS) alleviate the pain experienced during the bone marrow sampling procedure in addition to…
- Trial name
- TENS (NCT02005354)
- Testing
- Trans-cutaneous Electrical Nerve Stimulation (TENS), Standard pain relief (ie. local anaesthetic with or without inhaled nitrous oxide)
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- University Hospital Plymouth NHS Trust
Sleep Initiation and Maintenance Disorders
Effect of Eszopiclone on Sleep Disturbance and Pain in Cancer
To assess the effectiveness of Lunesta on cancer patients who have received chemotherapy and who require patient controlled analgesia (PCA), specifically to assess whether Lunesta will: improve sleep thereby decreasing need for…
- Trial name
- NCT00365261
- Testing
- Eszopiclone
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of California, San Diego
Rib Fracture, Rib Fracture Multiple
Ultrasound-Guided Percutaneous Cryoneurolysis to Treat Pain Following Thoracic Trauma
Thoracic trauma frequently involve rib fractures which can be very painful for 2-3 months. Unfortunately, pain is not simply a "symptom" of the injuries, but a significant cause of additional medical problems: pain causes people…
- Trial name
- NCT06069154
- Testing
- Cryoneurolysis, Local anesthetic peripheral nerve block
- Where
- 5 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of California, San Diego
Rib Fractures
Suzetrigine for Acute Pain Control in Patients With Multiple Rib Fractures
Rib fractures cause a significant amount of pain and are associated with an increased risk of lung infections, long hospitalization, and increased cost.
- Trial name
- NCT07145346
- Testing
- Suzetrigine (SUZ)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of California, Irvine
Tibia Fracture, Femur Fracture
Bimodal Analgesia as Form of Pain Control Post Long Bone Fracture
The purpose of this prospective randomized study is to evaluate the risks and benefits of using bimodal analgesia, (i.e. Narcotics and NSAIDS) vs Narcotics alone post long bone fracture.
- Conditions
- Tibia Fracture, Femur Fracture, Humerus Fracture
- Trial name
- NCT00240396
- Testing
- Narcotics alone, Narcotics and NSAIDS
- Where
- United States
- Sponsor
- Beth Israel Deaconess Medical Center
Secondary Malignant Neoplasm of Bone
Primary Pain Palliation in Bone Metastases Treated With Magnetic Resonance-guided Focused Ultrasound
Magnetic Resonance guided Focused Ultrasound (MRgFUS) has demonstrated to be effective for pain control through thermally-induced cell death and periosteal denervation caused by cortical heating relative to acoustic energy…
- Trial name
- NCT01693770
- Testing
- MRgFUS
- Where
- Italy
- Volunteers
- 18 people
- Sponsor
- University of Roma La Sapienza
Low Back Pain
Safety And Efficacy Assessment of the zLock Facet Fusion System- A Pilot Study
ZygoFix has developed a system consisting of zLOCK Facet Fusion System. The zLOCK Facet Fusion System is intended for single level stabilization of a spinal motion segment to promote bonny fusion of the joint.
- Trial name
- NCT04229316
- Testing
- zLOCK Facet Stabilization System
- Where
- Hungary
- Volunteers
- 24 people
- Sponsor
- ZygoFix
Collum Femoris Fracture, Pericapsular Nerve Group Block
the Pericapsular Nerve Group (PENG) and Suprainguinal Fascia Iliaca Blocks (SIFIB) in Elderly Patients
This clinical trial aims to compare the effect of the pericapsular nerve group (PENG) and suprainguinal fascia iliaca blocks (SIFIB) on pain management in elderly patients with subtrochanteric femur fractures.
- Conditions
- Collum Femoris Fracture, Pericapsular Nerve Group Block, Suprainguinal Fascia Iliaca Block
- Trial name
- NCT06277648
- Testing
- PENG block, SIFIB
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Haseki Training and Research Hospital
Scoliosis Idiopathic Adolescent Treatment, Scoliosis Idiopathic
Yoga for Back Pain in Adolescent Scoliosis
The Problem: Adolescent Idiopathic Scoliosis (AIS), the pre-eminent spinal pathology affecting over 5% of children and adolescents, presents a pronounced spinal curvature exceeding 10 degrees, with prevalence amongst female…
- Conditions
- Scoliosis Idiopathic Adolescent Treatment, Scoliosis Idiopathic, Scoliosis; Adolescence, Scoliosis
- Trial name
- AIS (NCT06242821)
- Testing
- Standard of Care (SOC), Yoga
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Johns Hopkins University
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