Clinical trials: Bone Pain
Hip Fracture, Postoperative Pain
Fascia Iliaca vs Femoral Nerve Block in Hip Fracture Patients
Hip fractures are common orthopedic injuries, especially in older adults, and surgical repair such as hip arthroplasty is often required.
- Conditions
- Hip Fracture, Postoperative Pain, Peripheral Nerve Block, Femoral Nerve
- Trial name
- CPTH (NCT07597317)
- Testing
- Fascia Iliaca Compartment Block (FICB)
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Central Park Teaching Hospital, Lahore
Low Back Pain, Mechanical, Degenerative Disc Disease Lumbar
Fusion or Not - a Study on Low Back Pain
Problems from the musculoskeletal system are one of the most common reasons for disability and sick leave. These problems include low back pain. Low back pain affects as many as 8 out of 10 individuals at some point in life.
- Trial name
- NCT06709391
- Testing
- Fusion surgery, Non-fusion surgery
- Where
- 4 sites in Sweden
- Volunteers
- 90 people
- Sponsor
- Uppsala University
Cancer Pain
Phase I Study of sss40 Injection for Moderate-to-Severe Bone Metastatic Cancer Pain
This is a Phase Ib/IIa, multicenter, sequential clinical trial evaluating the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of SSS40 injection in patients with moderate-to-severe bone metastatic cancer…
- Trial name
- NCT07008703
- Testing
- Injection of humanized nerve growth factor (NGF) antibody
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Shenyang Sunshine Pharmaceutical Co., LTD.
Post-traumatic Carpal Tunnel Syndrome, Complex Regional Pain Syndrome
Use of Compression Glove to Prevent Complications After Distal Radius Fractures: a Randomized Controlled Trial
Distal radius fractures (DRF) are the most common type of fracture in the human body, and a large proportion of DRFs result in complications.
- Conditions
- Post-traumatic Carpal Tunnel Syndrome, Complex Regional Pain Syndrome, Edema
- Trial name
- NCT01118715
- Testing
- Compression glove
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- J&M Shuler
Lumbar Disc Herniation
VR Therapy Effects in Lumbar Disc Herniation
This study aims to evaluate the effects of incorporating virtual reality (VR) therapy into routine physical therapy (RPT) on balance, pain, kinesiophobia, quality of life, and depression in individuals diagnosed with lumbar disc…
- Trial name
- NCT07309627
- Testing
- Conventional Physiotherapy, VR
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Uskudar University
Femoral Neck Fracture
Postoperative Pain Control After Hip Hemiarthroplasty: Intrathecal Morphine vs Periarticular Infiltration of Bupivacaine
Falls are a common problem in elderly people which they have to receive the operation. Hemiarthroplasty is one of the common orthopedics operations.
- Trial name
- NCT01219062
- Testing
- morphine, control, Bupivacaine
- Where
- 2 sites in Thailand
- Volunteers
- 10 people
- Sponsor
- Mahidol University
Femoral Neck Fractures
This is a Study to Verify if Periarticular Hip Injection of Corticosteroid After Hip Replacement Reduce the Pain and the Hospitalisation Time
The investigators are going to evaluate if periarticular corticosteroid injection during endoprothesis implantation can lead to any advantage to the patients, namely if it can reduce post-operative pain, lenght and cost of…
- Trial name
- NCT05023369
- Testing
- Dexamethasone is a steroid drug and will be administered as an injectable solution (4mg/ml)
- Where
- Switzerland
- Volunteers
- 110 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Lumbar Herniated Disc
Evaluation of Minimally Invasive Microdiscectomy Versus Conventional Open Microdiscectomy For Lumbar Herniated Disc
Overall Objective: To evaluate pain and functional status of patients undergoing surgical correction for lumbar herniated disc, pre- and post-surgery, using subjective (VAS, Oswestry, PSQI, Patient Expectation), as well as…
- Trial name
- NCT00927056
- Testing
- Microdiscectomy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Hip Fracture
The Effect of Facial Plane Blocks on Postoperative Recovery Quality in Hip Surgery
The aim of this study was to evaluate the effect of ultrasound-guided pericapsular nerve block, fascia iliaca compartment block, and femoral block on the quality of recovery as part of multimodal analgesia before hip surgery…
- Trial name
- NCT06389279
- Testing
- PENG block group, FIC block group, Femoral block group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Antalya Training and Research Hospital
Bone Metastasis
Multicenter Study of Magnetic Resonance-guided High Intensity Focused Ultrasound for Pain Palliation of Bone Metastases
The purpose of this study is to evaluate the effectiveness of the Philips Sonalleve Magnetic Resonance Imaging-guided High Intensity Focused Ultrasound (MR-HIFU) device for treating painful bone metastases.
- Trial name
- NCT01586273
- Testing
- MR-HIFU treatment for pain palliation of bone metastases
- Where
- 3 sites in Netherlands, South Korea and 1 more
- Volunteers
- 20 people
- Sponsor
- Philips Healthcare
Dental Pain, Dental Anxiety
Evaluation of the Sedative Effect of Contextualized Music Listening on Patient Pain and Anxiety in a Dental Care Setting
The goal of this clinical study is to determine whether listening to culturally and personally contextualized music can reduce pain and anxiety in adults undergoing dental procedures.
- Trial name
- NCT07543042
- Testing
- Baseline Assessment (T0), Control Condition - Silence (Pre-Music Phase), Music Listening Condition (Intervention Phase)
- Where
- Lebanon
- Volunteers
- 30 people
- Sponsor
- Rawane El Dimachki
Bone Lesion
Interventional Radiology in Bony Lesions
To explore the capability of the interventional radiology techniques in management of the painful bony lesions .
- Trial name
- NCT05738941
- Testing
- radiofrequency ablation, angioembolization
- Volunteers
- 50 people
- Sponsor
- Assiut University
Kyphosis
Comparison of Exercise With & Without Bracing in Office Workers With Kyphosis
The study aims to Compare PT and bracing in improving posture, pain, and functionality in patient with kyphosis. It also assess the additive benefits of combining PT with bracing.
- Trial name
- NCT06867003
- Testing
- physical therapy with bracing, physical therapy without bracing
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Riphah International University
Herniated Disc, Low Back Pain
Spine Patient Outcomes Research Trial (SPORT) - Intervertebral Disc Herniation
This study tests the effectiveness of different treatments for the three most commonly diagnosed lumbar (lower) spine conditions.
- Trial name
- SPORT (NCT00000410)
- Testing
- Diskectomy, Non-surgical treatments
- Where
- 13 sites in United States
- Volunteers
- 501 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Low Back Pain, Neck Pain
The Effect of Integrated CAM Treatment in Hospitalized Patients
This study investigates the effect of hospital-based intensive non-surgical treatment in musculoskeletal patients admitted to an integrated hospital that offers both complementary and alternative medicine (CAM) and conventional…
- Conditions
- Low Back Pain, Neck Pain, Knee Pain, Shoulder Pain
- Trial name
- NCT02257723
- Testing
- Herbal medicine, Acupuncture, Pharmacopuncture
- Where
- South Korea
- Volunteers
- 100,000 people
- Sponsor
- Jaseng Hospital of Korean Medicine
Postoperative Pain, Hip Fracture
Transcutaneous Nerve Stimulation for Post-operative Acute and Chronic Pain
Aim of the study to assess the efficacy of two modes of transcutaneous electrical nerve stimulation (TENS) on relief of postoperative acute pain after hip fracture surgery.
- Trial name
- NCT02642796
- Testing
- transcutaneous electric nerve stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Mustafa Kemal University
Sciatica Due to Intervertebral Disc Disorder
Electroacupuncture for Sciatica Due to Intervertebral Disc Displacement
This multicenter randomized controlled trial (RCT) will evaluate the therapeutic effectiveness and health-economics of electroacupuncture for sciatica due to intervertebral disc displacement in 3 compared groups…
- Trial name
- NCT02087462
- Testing
- Electroacupuncture (EA), Traction, Voltaren
- Where
- China
- Volunteers
- 324 people
- Sponsor
- Chengdu University of Traditional Chinese Medicine
Degenerative Disc Disease
Lumbar Degenerative Disc Disease Treatment With Bone Marrow Autologous Mesenchymal Stem Cells (MSV)
This trial pretends to validate for clinical use a bioengineered product composed of mesenchymal stem cells produced by the Instituto de Biologia y Genetica Molecular (IBGM), Valladolid (MSV, which have already been approved by…
- Trial name
- MSV-DISC (NCT02440074)
- Testing
- Autologous bone marrow mesenchymal stem cells
- Sponsor
- Red de Terapia Celular
Shoulder Osteoarthritis
CAM Procedure With BMAC for Shoulder OA
Researchers want to find out more about the side effects of Bone Marrow Aspirate Concentrate (BMAC) and what doses of BMAC are safe for people.
- Trial name
- NCT04826224
- Testing
- Concentrated bone marrow aspirate administration after Comprehensive Arthroscopic Management (CAM) surgical procedure.
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Shane A. Shapiro
To Evaluate the Effect of Exercise With Virtual Glasses on Pain, Activities of Daily Living and Quality of Life
Individuals With Lumbar Disc Hernia Exercising With Virtual Reality Glasses
The purpose of this research; exercise performed with virtual reality glasses for individuals with lumbar disc herniation; The aim of this study is to examine the effects on pain, activities of daily living, quality of life and…
- Trial name
- NCT05463588
- Testing
- Exercising with virtual reality glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ataturk University
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