Clinical trials: Bone Pain
Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders
Studying Fentanyl in Patients With Cancer
RATIONALE: Studying blood samples from cancer patients undergoing pain treatment in the laboratory may help doctors learn more about how pain drugs work in the body.
- Conditions
- Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
- Trial name
- NCT00899951
- Testing
- fentanyl citrate, pharmacological study
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Neoplasms, Cementoplasty
Prospective Study Determining the Pain Response, Functional Interference and Quality of Life in Patients Undergoing Radiofrequency Ablation Assisted Vertebroplasty/ Cementoplasty
Bone metastases are a cause of significant morbidity in cancer patients. In patients who die from breast, prostate, and lung cancer, autopsy studies have shown that up to 85% have evidence of bone metastases at the time of death…
- Conditions
- Neoplasms, Cementoplasty, Quality of Life
- Trial name
- RFA (NCT02082314)
- Testing
- RFA Vertebroplasty
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Hip Fractures
PENG vs Femoral Block for Hip Fracture Analgesia
This study aims to compare the Pericapsular Nerve Group (PENG) block with femoral block for hip fracture pain. Participants presenting to the hospital with a diagnosis of hip fracture and consenting to analgesic block will…
- Trial name
- NCT07073209
- Testing
- PENG Block Administration, Femoral Block Administration, Bupivacaine , epinephrine Dexamethasone
- Where
- United States
- Volunteers
- 352 people
- Sponsor
- Weill Medical College of Cornell University
Low Back Pain, Sciatica
Integrated Supported Biopsychosocial Self-Management for Back Related Leg Pain
Guidelines advocate several complementary modalities as alternatives to drugs and other invasive treatments for chronic low back pain (LBP) conditions.
- Conditions
- Low Back Pain, Sciatica, Back Related Leg Pain, Pain, Chronic
- Trial name
- SUPPORT (NCT05022121)
- Testing
- Supported Biopsychosocial Self-Management (SBSM), Medical Care
- Where
- 2 sites in United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cervical Spondylosis, Neck Pain
Efficacy of Acupuncture at Lieque (LU7) for Neck Pain in Cervical Spondylosis
Cervical spondylosis is a common degenerative disorder of the cervical spine that often leads to chronic neck pain, stiffness, and reduced daily functioning.
- Trial name
- NCT07151404
- Testing
- Acupuncture at LU7 (Lieque) + Electroacupuncture, Electroacupuncture Only
- Where
- Vietnam
- Volunteers
- 130 people
- Sponsor
- Nguyen Ngoc Doan Thuy
Degenerative Disc Disease, Lumbar Spondylosis
Benefit of Lumbar Bracing for Chronic Low Back Pain Due to Degenerative Disc Disease
The main objectives of this study are to evaluate the benefits of back bracing in the symptomatic management of patients with CLBP due to degenerative lumbar disc disease.
- Conditions
- Degenerative Disc Disease, Lumbar Spondylosis, Low Back Pain
- Trial name
- NCT03484403
- Testing
- Lumbar back brace, Back school
- Volunteers
- 61 people
- Sponsor
- Dallas VA Medical Center
Lumbar Spinal Stenosis, Erector Spinae Plane Block
Erector Spinae Plane Block After Lumbar Spinal Stenosis Surgery
Lumbar spinae stenosis surgery is a frequent intervention resulting in important postoperative pain. Management of this postoperative pain is thus important. Different pain management therapies exist.
- Trial name
- NCT04403360
- Testing
- ESPB, Local infiltration by the surgeon
- Where
- Belgium
- Volunteers
- 80 people
- Sponsor
- Clinique Saint Pierre Ottignies
Hip Fractures
Patients With Acute Hip Fractures Will Receive Either the PENG Block or no Block Respectively.
Hip fracture pain is often severe and traditionally managed by systemic opioids which have increased risk of side effects in frail elderly patients.
- Trial name
- PENGBlock (NCT04996979)
- Testing
- Ropivacaine 0.5% Injectable Solution
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- Singapore General Hospital
Postoperative Pain, Wrist Fracture
Comparing Efficacity of Analgesia Between Ultrasound-guided Nerve Block and Local Infiltration After Wrist Fracture Surgery
Distal radial fracture reparations by volar plating are often managed under regional anaesthesia, but are associated with severe pain when the block ends.
- Trial name
- BNINF (NCT02693288)
- Testing
- Local infiltration anesthesia
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Lumbar Disc Herniation
The Effect of Expressive Touch and Music Applied After Lumbar Disc Hernia Surgery.
Patients undergoing lumbar hernia surgery will be divided into expressive touch, music and control groups. Pre-test and post-test pain levels, vital signs, and NIRS values of the patients will be measured.
- Trial name
- NIRS (NCT04765774)
- Testing
- Ekspressive touch, Music
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Inonu University
Herniated Intervertebral Disc
Artificial Intelligence Assisted Spine Rehabilitation in Cervical Disc Herniation
The aim of this study is to investigate the effect of artificial intelligence-assisted spinal rehabilitation in neck hernia compared to traditional methods.
- Trial name
- NCT06632028
- Testing
- artificial intelligence assisted spinal rehabilitation, conventional therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Okan University
Lumbar Spine Disc Herniation, Spinal Stenosis
Pre-surgery Physiotherapy for Patients With Specific Low Back Pain
The aim is to study if pre-surgery physiotherapy improves function, pain and health in patients with specific low back pain scheduled for surgery. Patients are followed over a two year period.
- Conditions
- Lumbar Spine Disc Herniation, Spinal Stenosis, Spondylolisthesis, Grade 4
- Trial name
- PREPARE (NCT02454400)
- Testing
- Pre-surgery physiotherapy, Waiting-list
- Where
- Sweden
- Volunteers
- 197 people
- Sponsor
- Linkoeping University
Spine Disease, Regional Anaesthesia
Erector Spine Block for Back Surgery
In spine surgery postoperative pain can often be severe and difficult to treat.With the use of ultrasound, the performance of plane blocks and other techniques like root blocks, facet infiltration have become possible without the…
- Trial name
- NCT03214536
- Testing
- erector spinae block, Ropivacaine, Spine surgery
- Where
- 2 sites in Belgium
- Volunteers
- 15 people
- Sponsor
- University Hospital, Antwerp
Lumbar Spine Disease
Efficacy of Motor Control Exercise Program After Lumbar Spinal Decompression Surgery
The study will be conducted with volunteer patients who have undergone lumbar decompression surgery and who are followed up by the Neurosurgery outpatient clinic of Fethiye State Hospital.
- Trial name
- NCT06014632
- Testing
- Rehabilitation, Control
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Muğla Sıtkı Koçman University
Lumbar Disc Herniation, Postoperative Pain
Comparison of the Effects of Quadratus Lumborum Block and Retrolaminar Block on Postoperative Pain in Lumbar Disc Herniation Surgery
This study aims to compare the analgesic efficacy of quadratus lumborum block (QLB) and retrolaminar block (RLB) in patients undergoing lumbar disc herniation surgery.
- Trial name
- NCT07166250
- Testing
- Quadratus Lumborum Block, Retrolaminar Block
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Kocaeli University
Postmenopausal Osteoporosis
Efficacy and Safety of Minodronate in Patients With Low Back Pain
This study will provide objective evidence for the efficiency and safety of minodronate in the treatment of postmenopausal osteoporosis with low back pain protocol.
- Trial name
- NCT05645289
- Testing
- Minodronate, Alendronate
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Peking University Third Hospital
Herniated Disc
Nucleoplasty for Contained Herniated Lumbar Discs
This is a prospective randomised double blind comparison trial. Fifty patients will be included, 25 in the nucleoplasty treatment group, 25 in the control group. The nucleoplasty group will undergo the nucleoplasty treatment.
- Trial name
- NCT00124774
- Testing
- Nucleoplasty
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Rijnstate Hospital
Radius Fracture Distal, Surgery
Volar Locking Plate Versus External Fixation for Distal Radius Fracture - a Longterm Follow up
A 10-year follow up of a fusion of two earlier published randomized controlled trials. 203 patients with displaced distal radius fractures were randomized to surgery with a volar locking plate or external fixation.
- Conditions
- Radius Fracture Distal, Surgery, Surgery--Complications, Treatment Complication
- Trial name
- EXTEND (NCT05371938)
- Testing
- Volar locking plate, external fixation
- Where
- Sweden
- Volunteers
- 203 people
- Sponsor
- Olof Skoldenberg
Lumbar Disc Herniation, Lumbar Disc Surgery
Effectiveness of Virtual Reality-Assisted Physical Therapy in the Acute Phase After Lumbar Disc Surgery
The goal of this clinical trial is to evaluate the effectiveness of virtual reality-assisted physical therapy in the acute postoperative period after lumbar disc surgery.
- Trial name
- NCT07204197
- Testing
- Virtual Reality-Assisted Physical Therapy, Conventional Physical Therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Hacettepe University
Distal Radius Fracture
Effects of Concentric Exercise With and Without Mulligan Wrist Mobilization After Distal Radius Fracture.
The distal end of the radius is defined as the area three centimeters proximal to the radio carpal joint, where the radius interfaces with the lunate and scaphoid bone of the wrist.
- Trial name
- NCT05405023
- Testing
- Concentric exercises with wrist mobilization, Concentric exercises without wrist mobilization
- Where
- Pakistan
- Volunteers
- 18 people
- Sponsor
- Riphah International University
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