Clinical trials: Bone Resorption, active
Alveolar Bone Loss
Effectiveness of Alveolar Bone Preservation in Alveoli With Infectious Process
Alveolar ridge preservation (ARP) is a surgical technique that aims to minimize the degree of dimensional changes following extraction.
- Trial name
- NCT06661863
- Testing
- alveolar ridge preservation with bioactive glass, alveolar ridge preservation with autologous bone
- Where
- Ecuador
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
Alveolar Bone Loss, Dental Implant
Magnetic Mallet Vs Conventional Drilling in D4 Posterior Maxilla
The goal of this clinical trial is to evaluate whether the magnetic mallet technique improves primary implant stability and clinical outcomes compared with conventional drilling during dental implant placement in the posterior…
- Conditions
- Alveolar Bone Loss, Dental Implant, Osseodensification Drilling Technique
- Trial name
- NCT07424820
- Testing
- Conventional drilling osteotomy, Magnetic mallet osteotomy
- Where
- Iraq
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Mosul
Peri-Implantitis, Alveolar Bone Loss
Non-Surgical Treatment of Peri-Implantitis With Ultrasonic Carbon Tip
As the frequency of dental implants increases, the incidence of complications and peri-implant diseases also increases. Early diagnosis and treatment of the disease is important to prevent consequences up to implant loss.
- Trial name
- NCT06514677
- Testing
- Ultrasonic Carbon Tip, Titanium Curette
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Alveolar Ridge Deficiency, Alveolar Bone Loss
Novel Synthetic Membrane for Horizontal Bone Augmentation: A Case Series
The goal of this clinical study is to learn if the Inox Nanoksa G-Plus membrane works to rebuild bone in the upper or lower jaw (ridge augmentation) for adults who need dental implants but do not have enough bone width or height.
- Trial name
- NCT07701473
- Testing
- Inox Nanoksa G-Plus Membrane, Particulate Bone Graft
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bone Resorption
Bone Substitutes Outcomes - Post Market Follow-up
A Post-Market Clinical Follow-Up (PMCF) Study to collect clinical data on safety and performance of all TEKNIMED Bone Substitute range of products: CERAFORM, TRIHA+, NANOGEL, and all their private labels.
- Trial name
- NCT06374342
- Testing
- Bone defect, Spine fusion, Cage filling
- Where
- 6 sites in France, Germany
- Volunteers
- 425 people
- Sponsor
- Teknimed
Alveolar Bone Resorption, Alveolar Ridge Enlargement
Is Cross-linked Hyaluronic Acid a Biologic Alternative for Alveolar Ridge Preservation?
Even after atraumatic tooth removal and/or immediate implant placement, some reduction of the alveolar ridge dimension is expected.
- Conditions
- Alveolar Bone Resorption, Alveolar Ridge Enlargement, Tooth Extraction, Hyaluronic Acid
- Trial name
- NCT07496437
- Testing
- DBBM + FGG, Hyaluronic acid + collagen sponge + FGG
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Spinal Cord Injury, Spinal Cord Injuries
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and…
- Conditions
- Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injury
- Trial name
- NCT04460872
- Testing
- Testosterone Enanthate, Locomotor Training
- Where
- 2 sites in United States
- Volunteers
- 21 people
- Sponsor
- North Florida Foundation for Research and Education
Alveolar Ridge Augmentation, Bone Substitutes
Alveolar Ridge Preservation (ARP) Study Using Alloplastic Biomaterial and a Resorbable Synthetic Membrane. A Digital Workflow (CBCT/Scanner) Evaluates Hard and Soft Tissue Volumetric Changes at 4 Months, Validating Support for the Gingival Phenotype and Buccal Bone Plate.
The dimensional collapse of the alveolar ridge following tooth extraction represents a critical challenge for implant rehabilitation.
- Conditions
- Alveolar Ridge Augmentation, Bone Substitutes, Guided Tissue Regeneration, Periodontal, Cone-Beam Computed Tomography
- Trial name
- NCT07879495
- Testing
- Alveolar Ridge Preservation using a synthetic alloplastic bone substitute and a resorbable polymer membrane, Minimally invasive flapless tooth extraction followed by unassisted spontaneous healing
- Volunteers
- 28 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Dental Implant, Tooth Extraction
Soft Tissue Volume Changes After Immediate Implants With Two Different Techniques
The aim is to comparatively evaluate the soft tissue volume changes that occur after tooth extraction and immediate dental implant placement using two different surgical techniques.
- Conditions
- Dental Implant, Tooth Extraction, Bone Resorption
- Trial name
- NCT04803110
- Testing
- Dental implant placement after tooth extraction
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Aula Dental Avanzada
Bone Remodeling, Energy Metabolism
Retrospective Monocentric Evaluation of Biomarkers Associated With Bone, Muscle and Energy Metabolism
Bone is a metabolically active tissue undergoing continuous remodeling through the coordinated actions of osteoclasts (resorption), osteoblasts (formation), and osteocytes (regulation).
- Trial name
- OVAD (NCT07454252)
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Edentulous Posterior Maxilla, Maxillary Sinus Pneumatization
Graftless TSFE Via Self-tapping Implants
This prospective clinical trial aims to evaluate the efficiency, safety, and reliability of a minimally invasive graftless transcrestal sinus lifting approach with simultaneous dental implant placement in patients with edentulous…
- Conditions
- Edentulous Posterior Maxilla, Maxillary Sinus Pneumatization, Alveolar Bone Atrophy
- Trial name
- G-TSFE (NCT07424742)
- Testing
- Graftless Transcrestal Sinus Membrane Elevation with Simultaneous Implant Placement
- Where
- Yemen
- Volunteers
- 20 people
- Sponsor
- Sana'a University
Bone Resorption
Timing of Soft Tissue Grafting Following Immediate Implant Placement
Patients undergoing single immediate implant placement (IIP) in the premaxilla will be invited to participate in this randomized controlled trial (RCT).
- Trial name
- NCT05537545
- Testing
- Soft tissue grafting
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Ghent
Atrophic Edentulous Maxilla, Zygomatic Implants
Evaluation of Zygomatic Implant Placement Accuracy Using Fully Metallic vs Resin-based Static Surgical Guides in Severely Atrophic Maxilla
Some patients lose a large amount of bone in the upper jaw. When this happens, it can be difficult to place regular dental implants. In these cases, special implants called zygomatic implants can be used.
- Conditions
- Atrophic Edentulous Maxilla, Zygomatic Implants, Guided Surgery, Dental Implant
- Trial name
- guided surgery (NCT07551024)
- Testing
- Resin surgical Guide, Group B (Metallic nickel Guide)
- Where
- Egypt
- Volunteers
- 4 people
- Sponsor
- Future University in Egypt
Alveolar Ridge Resorption
Different Approaches for Alveolar Ridge Preservation
Following tooth extraction, physiologic remodeling of the alveolar ridge results in significant horizontal and vertical bone resorption, often accompanied by soft tissue collapse.
- Trial name
- NCT07818447
- Testing
- Bone Allograft + Autologous Platelet-Rich Fibrin (PRF) Membrane, Control group, Bone Allograft + Resorbable Guided Bone Regeneration Membrane
- Where
- Greece
- Volunteers
- 51 people
- Sponsor
- Danae A. Apatzidou
Osseodensification, Bone Expansion
Osseodensification for Narrow Alveolar Ridge Expansion
This prospective, single-arm, non-randomized interventional clinical study was designed to evaluate the immediate horizontal dimensional change in narrow alveolar ridges following osseodensification-assisted dental implant-site…
- Conditions
- Osseodensification, Bone Expansion, Alveolar Bone Loss, Jaw, Edentulous, Partially
- Trial name
- OD-RridgeExp (NCT07436533)
- Testing
- Densah burs (Osseodensification Technique)
- Where
- Yemen
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Science and Technology, Yemen
Tooth Extraction, Tooth Extraction Site Healing
Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction
The goal of this randomized clinical trial is to assess whether β-TCP (Beta-Tricalcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction.
- Conditions
- Tooth Extraction, Tooth Extraction Site Healing, Alveolar Bone Grafting, Alveolar Bone Loss
- Trial name
- BTCPARPBV (NCT07638319)
- Testing
- Neocement Inject P® (Beta-Tricalcium Phosphate)
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Lymphatic Diseases, Lymphatic Abnormalities
A Prospective Natural History Study of Lymphatic Anomalies
Background: The lymphatic system is a network of vessels that carry a clear fluid called lymph through the body. Problems in the lymphatic system can cause pain, fluid buildup, and issues with immunity.
- Trial name
- NCT05731141
- Where
- 2 sites in United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Osteolysis
Incidence & Clinical Significance of Osteolysis Following PEEK Suture Anchor Use in Hand & Wrist Surgery
This prospective observational study evaluates the incidence \& clinical significance of osteolysis following polyetheretherketone (PEEK) suture anchor use in hand \& wrist surgery.
- Trial name
- NCT06824545
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Colorado, Denver
Edentulous Maxilla, Maxillary Bone Loss
NobelZygoma TiUltra Implant System Study
The goal of this prospective study is to assess short term (12-months) clinical outcomes of NobelZygoma TiUltra implants and Multi-unit Abutment Xeal in the rehabilitation of participants with severely atrophic maxilla treated…
- Conditions
- Edentulous Maxilla, Maxillary Bone Loss, Atrophic Maxilla
- Trial name
- NCT07258940
- Testing
- NobelZygoma™ 0° CC TiUltra™implant ; NobelZygoma™ 45° Ext Hex TiUltra™ implant, Multi-Unit Abutment Xeal Zygoma Ext Hex RP; 17° Multi-Unit Abutment Xeal Zygoma Ext Hex RP; 45° Multi.Unit Abutment Xeal Zygoma CC RP; 60° Multi-Unit Abutment Xeal Zygoma CC RP
- Where
- 2 sites in Italy, Switzerland
- Volunteers
- 85 people
- Sponsor
- Nobel Biocare
Alveolar Bone Loss, Dental Implant
Socket Preservation - A Randomized Clinical Implementation in a Student Setting
Preserving the ridge dimension after tooth extraction aims to avoid the need for bone augmentation procedures before implant placement.
- Conditions
- Alveolar Bone Loss, Dental Implant, Bone Augmentation
- Trial name
- NCT06539299
- Testing
- Socket Preservation
- Volunteers
- 51 people
- Sponsor
- Sigmund Freud PrivatUniversitat