Clinical trials: Bone Resorption After Tooth Extraction
Alveolar Bone Resorption, Tooth Extraction
Ridge Preservation Following Tooth Extraction
An animal study and our pilot human study demonstrated that placing a smooth-surface titanium bone screw (TBS) over the buccal plate of an extraction socket resulted in less dimensional changes of the alveolar ridge along with no…
- Trial name
- NCT05485194
- Testing
- Reducing dimensional changes following tooth extraction
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Alveolar Bone Loss, Periodontal Pocket
Regenerative Gel (Emdogain®) for Healing After Wisdom Tooth Extraction
This study investigates whether the intraoperative application of a specialized regenerative gel (Emdogain®) can improve the periodontal health of the mandibular second molar by preventing or reducing the formation of tissue…
- Conditions
- Alveolar Bone Loss, Periodontal Pocket, Impacted Tooth With Abnormal Positioning
- Trial name
- NCT07718932
- Testing
- Enamel Matrix Derivative (Emdogain®)
- Where
- 2 sites in Greece
- Volunteers
- 70 people
- Sponsor
- Aristotle University Of Thessaloniki
Loss of Teeth Due to Extraction, Alveolar Bone Loss
Relate Tooth Alveolar Extraction Socket Anatomy to Alveolar Remodeling Rate
In patients that are going to be subjected to a tooth extraction in the anterior maxillary (from canine to canine) does the position of the intact alveolar socket related to maxillary basal bone interferes with the rate of…
- Conditions
- Loss of Teeth Due to Extraction, Alveolar Bone Loss, Bone Resorption
- Trial name
- NCT01963884
- Testing
- Tooth Extraction, Cone-Beam technology evaluation, Measure Alveolar Socket Remodeling
- Where
- Portugal
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Implantology Institute
Alveolar Bone Loss
Alveolar Ridge Preservation Techniques After Tooth Extraction
The aim of the present randomized controlled trial (RCT) was to evaluate the efficacy of different alveolar ridge preservation (ARP) techniques on hard tissue dimensional alterations after tooth extraction, based on clinical…
- Trial name
- NCT04934813
- Testing
- Alveolar ridge preservation
- Where
- Greece
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Loss of Teeth Due to Extraction, Alveolar Bone Loss
Regeneration of Alveolar Sockets With rhBMP-2-loaded Bovine Bone Mineral
Aim of the present investigation will be to evaluate the efficacy and safety of a granulate of rhBMP-2- loaded bovine bone mineral (rhBMP-2-BBM) as alveolar bone regeneration procedure following tooth extraction.
- Conditions
- Loss of Teeth Due to Extraction, Alveolar Bone Loss, Edentulous Alveolar Ridge
- Trial name
- PROTEOGRAFT (NCT05717478)
- Testing
- rhBMP-2-BBM, Bio-Oss+Bio-Gide
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad Complutense de Madrid
Tooth Loss / Rehabilitation, Tooth Extraction
Ovate Pontic Versus Essix Provisional After Tooth Extraction and Alveolar Ridge Preservation (Pontic-Essix)
This randomized controlled trial compares two provisional socket-sealing concepts following single non-molar tooth extraction and alveolar ridge preservation: a fixed, tooth-supported, 3D-printed ovate pontic provisional…
- Conditions
- Tooth Loss / Rehabilitation, Tooth Extraction, Alveolar Bone Loss, Alveolar Ridge Augmentation
- Trial name
- Pontic-Essix (NCT07748871)
- Testing
- Bio-Oss Collagen, Mucograft Seal, Fixed 3D-printed ovate pontic provisional restoration
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Bern
Tooth Extraction, Tooth Extraction Site Healing
Assessment of the Impact of Neocement Inject P® (Beta-Tricalcium Phosphate) on Bone Volume in Alveolar Ridge Preservation After Tooth Extraction
The goal of this randomized clinical trial is to assess whether β-TCP (Beta-Tricalcium Phosphate) improves alveolar ridge preservation (ARP) in patients who need tooth extraction.
- Conditions
- Tooth Extraction, Tooth Extraction Site Healing, Alveolar Bone Grafting, Alveolar Bone Loss
- Trial name
- BTCPARPBV (NCT07638319)
- Testing
- Neocement Inject P® (Beta-Tricalcium Phosphate)
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Egas Moniz - Cooperativa de Ensino Superior, CRL
Bone Loss, Alveolar
A Randomized Control Trial Phase (IIIa) Unicentric, Placebo Controlled, Double-Blinded Efficacy and Safety of Topical Alendronic Acid on Alveolar Bone Remodeling After Tooth Extraction
The purpose of the study is to determine the efficacy and safety of the effects of a topical medication on bone remodeling after dental extraction, in order to establish whether such treatment can be a new therapeutic option for…
- Trial name
- XEOLAS (NCT05602493)
- Testing
- Soludronate®, sterile saline
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Xeolas Pharmaceuticals Limited
Dental Implant, Tooth Extraction
Soft Tissue Volume Changes After Immediate Implants With Two Different Techniques
The aim is to comparatively evaluate the soft tissue volume changes that occur after tooth extraction and immediate dental implant placement using two different surgical techniques.
- Conditions
- Dental Implant, Tooth Extraction, Bone Resorption
- Trial name
- NCT04803110
- Testing
- Dental implant placement after tooth extraction
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Aula Dental Avanzada
Tooth Loss
Healing Dynamics in Human Extraction Sockets Grafted With Bio-Oss Collagen®
The purpose of this study is to clinically, radiographically and histologically evaluate the healing sequence of post-extraction sockets grafted with Bio-Oss Collagen® at 3, 6 and 9 months following tooth extraction in…
- Trial name
- NCT03659617
- Testing
- xenograft (BioOss Collagen)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Alveolar Bone Loss, Alveolar Ridge Resorption After Extraction
THBC/CGF for Alveolar Bone Regeneration: A Real-World Study
This study aims to combine real-world research with relevant bone repair materials and techniques to improve alveolar bone resorption in extraction sockets following impacted wisdom tooth removal, while achieving effective bone…
- Conditions
- Alveolar Bone Loss, Alveolar Ridge Resorption After Extraction, Tooth, Impacted
- Trial name
- NCT07779421
- Testing
- Temperature-sensitive hydroxybutyl chitosan-loaded concentrated growth factor, Temperature-sensitive hydroxybutyl chitosan, Autologous Concentrated Growth Factor
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Stomatological Hospital Affiliated with Fujian Medical University
Bone Resorption After Tooth Extraction
3D Printed Scaffold Device for Ridge Preservation After Tooth Extraction
Following tooth extraction, the socket heals naturally with bone in 1 to 2 months. This healing process occurs with substantial reduction of the original height and width of the alveolar ridge.
- Trial name
- NCT03735199
- Testing
- PCL-TCP scaffold, Geistlich Bio-Gide collagen membrane
- Where
- Singapore
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Dental Centre, Singapore
Tooth Extraction, Bone Graft
Resorbable vs Non-resorbable Bone Substitute at Immediate Post-extractive Single Implants
This study compares two bone graft materials used when placing a dental implant right after tooth removal. One graft fully dissolves (GTO®), the other only partly (Apatos®).
- Conditions
- Tooth Extraction, Bone Graft, Alveolar Bone Loss, Dental Implant
- Trial name
- NCT07047131
- Testing
- GTO® (fully resorbable bone substitute), Apatos® (partially resorbable bone substitute)
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Marco Esposito
Alveolar Bone Loss, Loss of Teeth Due to Extraction
Evaluation of OSSIX-Plus Resorbable Collagen Membranes for Alveolar Ridge Preservation Following Exodontia
The purpose of this study is to evaluate clinically, histologically and radiographically the healing of extraction sockets covered with a resorbable collagen membrane (OSSIX-Plus) 12 weeks following exodontia.
- Conditions
- Alveolar Bone Loss, Loss of Teeth Due to Extraction, Edentulous Alveolar Ridge
- Trial name
- OSSIX (NCT00639860)
- Testing
- OSSIX-Plus
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- William Giannobile
Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption
Peri-Implant Hard and Soft Tissue Changes After Immediate Implant Placement With Socket Shield and Immediate Restoration Versus Early Implant Placement in the Esthetic Zone
This randomized controlled clinical trial aims to compare peri-implant hard and soft tissue dimensional changes following immediate implant placement with the socket shield technique and immediate restoration versus early type II…
- Conditions
- Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption, Partial Edentulism of the Maxilla
- Trial name
- NCT07468760
- Testing
- Socket Shield, Early Implant Placement
- Where
- United Arab Emirates
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Alveolar Bone Loss
Clinical, Radiographical, Histological Evaluation and Blood Flow Analysis of Alveolar Ridge Preservation
With alveolar ridge preservation (ARP) ridge resorption following extraction may be reduced. Several materials and techniques have been advocated for ARP.
- Trial name
- NCT05674331
- Testing
- Extraction site development technique, autogenous tooth bone graft, Socket seal technique
- Where
- Hungary
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Semmelweis University