Clinical trials: Borderline Personality Disorder (BPD)
Borderline Personality Disorder
DBT in Borderline Personality Disorder
Subjects will receive a 6-month course of DBT, consisting of one 90-minute group and one 60-minute individual session per week as well as telephone availability of the individual therapist.
- Trial name
- NCT00252031
- Testing
- Dialectical Behavioral Therapy
- Where
- United States
- Sponsor
- Bronx VA Medical Center
Borderline Personality Disorder (BPD)
Application and Effectiveness of the STEPPS in Patients with BPD, Extending to Their Families with the FC Program
The present research project is framed within the issue of Borderline Personality Disorder (BPD). This condition stands as one of the most common challenges encountered within the mental health services of the National Health…
- Trial name
- NCT06195553
- Testing
- STEPPS plus Family Connections, STEPPS
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Universitat Jaume I
Heavy MHS Use, General Psychopathology
Efficacy of Time-limited Psychodynamic Psychotherapy and Informed Clinical Management in BPD High MHS Users
Subjects affected with severe Borderline Personality Disorder (BPD) are often heavy users of Mental Health Services (MHS). This study evaluates the efficacy of the addition of Sequential Brief Adlerian Psychodynamic Psychotherapy…
- Conditions
- Heavy MHS Use, General Psychopathology, Working Alliance
- Trial name
- HUMSH (NCT01356069)
- Testing
- SB-APP, treatment as usual
- Volunteers
- 35 people
- Sponsor
- University of Turin, Italy
Borderline Personality Disorder, Post-Traumatic Stress Disorders
Outcome of Crisis Intervention for Subjects With Borderline Personality Disorder or Post-Traumatic Stress Disorder
Dr. Laddis will test a hypothesis about the nature and the management of behavioral crises in patients with borderline personality disorder (BPD) or post-traumatic stress disorder (PTSD).
- Trial name
- NCT00269139
- Testing
- Crisis resolution
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Laddis, Andreas, M.D.
Borderline Personality Disorder (BPD)
Cortical Plasticity of the Tactile Mirror System in Borderline Personality Disorder
People with borderline personality disorder (BPD) show alterations in the empathic abilities, which may involve the functioning of the mirror neuron system in the somatosensory domain.
- Trial name
- SG2019-EXP2 (NCT06702215)
- Testing
- Cross-modal paired associative stimulation (cm-PAS) protocol
- Where
- Italy
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Borderline Personality Disorder, Borderline Personality Disorder (BPD)
Conceptualizing Borderline Personality Disorder as a Relationship Use Disorder
This study aims to explore a novel conceptualization of Borderline Personality Disorder (BPD) as a "Relationship Use Disorder." The research proposes that BPD shares key features with behavioral addictions, specifically addiction…
- Conditions
- Borderline Personality Disorder, Borderline Personality Disorder (BPD), Bipolar Disorder (BD)
- Trial name
- TLUR (NCT07337889)
- Testing
- Relationship-use questionnaire
- Where
- France
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Borderline Personality Disorder (BPD), Complex Post-Traumatic Stress Disorder (CPTSD)
Implementing a Therapy for Complex Trauma in French-Speaking Settings
Many individuals living with borderline personality disorder (BPD) have experienced childhood trauma, such as abuse or neglect. A significant number of them also meet the criteria for post-traumatic stress disorder (PTSD).
- Conditions
- Borderline Personality Disorder (BPD), Complex Post-Traumatic Stress Disorder (CPTSD), Post-Traumatic Stress Disorder, PTSD
- Trial name
- TRAUL (NCT07123974)
- Testing
- Dialectical Behaviour Therapy for Post-Traumatic Stress Disorder (DBT-PTSD)
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Borderline Personality Disorder
Stress & Social Cognition in BPD (part 2)
The investigators will examine how a combination of pharmacological mineralocorticoid receptor (MR) stimulation and psychosocial stress will influence prosocial behavior in patients with Borderline Personality Disorder (BPD)…
- Trial name
- SOKO-2 (NCT05310253)
- Testing
- Fludrocortisone, Trier Social Stress Test (TSST)
- Where
- Germany
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Borderline Personality Disorder (BPD)
Researching the Effectiveness of a Alivis, a Digital Health Application for Borderline Personality Disorder
This randomized controlled trial (RCT) with 470 patients diagnosed with Borderline Personality Disorder (BPD) aims to investigate the effectiveness of the unguided digital therapeutic alivis for patients with BPD as defined in…
- Trial name
- REVALDI-BPD (NCT06601907)
- Testing
- alivis
- Where
- Germany
- Volunteers
- 286 people
- Sponsor
- Gaia AG
Borderline Personality Disorder
The Effect of Oxytocin Administration on Interpersonal Cooperation in Borderline Personality Disorder Patients and Healthy Adults
The study will examine behavioral patterns and underlying neural correlates which distinguish patients with borderline personality disorder (BPD) from healthy subjects as they participate in a two-person trust game and will…
- Trial name
- NCT02225600
- Testing
- 40 IU Intranasal Oxytocin, 24 IU intranasal Oxytocin
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Borderline Personality Disorder
Seroquel Extended Release (XR) for the Management of Borderline Personality Disorder (BPD)
The Primary objective of this study is to evaluate Seroquel XR in the treatment of borderline personality disorder (BPD). As in many initial randomized control trials, the study will be of relatively short duration - 8 weeks - to…
- Trial name
- NCT00880919
- Testing
- quetiapine extended-release
- Where
- 3 sites in United States
- Volunteers
- 95 people
- Sponsor
- University of Minnesota
Borderline Personality Disorder, Borderline Personality
Treatment of Borderline Personality Disorder With rTMS
This project studies the effectiveness of brain stimulation on borderline personality disorder (BPD) symptoms. This study is blinded, randomized and will enroll up to 30 participants.
- Conditions
- Borderline Personality Disorder, Borderline Personality, BPD - Borderline Personality Disorder
- Trial name
- ClinicalBPD (NCT07197502)
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of California, Los Angeles
Borderline Personality Disorder
A Double Blind Crossover Study on the Effect of MPH on Decision-making Ability of Adults With BPD Compared to Adults With ADHD and Healthy Adults
The study assesses the effect of Ritalin on working memory,attention,and decision-making measures in adults with BPD and compares it to its effect on healthy adults and adults with BPD (using data form study SHA 01-10), in a…
- Trial name
- NCT01426984
- Testing
- methylphenidate
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Shalvata Mental Health Center
Posttraumatic Stress Disorder, Family Members
Testing a Peer-led Trauma-focused Intervention for Significant Others of Those With BPD
This project involves developing and piloting a peer-led intervention focused on posttraumatic stress symptoms for the family members and significant others of people with borderline personality disorder.
- Conditions
- Posttraumatic Stress Disorder, Family Members, Spouses
- Trial name
- NCT06135090
- Testing
- Trauma Recovery Program (official title TBD)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- York University
Borderline Personality Disorder
MRI Imaging in Borderline Personality Disorder
MRI Study for females ages 18-45 with Borderline Personality Disorder(BPD): This study is a non-treatment study that involves 2 visits. Study Hypothesis: 1.
- Trial name
- NCT00275288
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Borderline Personality Disorder
Staff Nurse Perceptions of MBT Skills Training for Working With BPD in AMH
Despite expert opinion unconvinced of any value for hospitalization in caring for people with borderline personality disorder (BPD), this patient group still accounts for a significant proportion of adult acute mental health…
- Trial name
- NCT02239055
- Where
- United Kingdom
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Aberdeen
Personality Disorder, Borderline
Effectiveness of the Iconic Therapy for Borderline Personality Disorder Symptoms
Borderline personality disorder (BPD) is the most prevalent personality disorder in young community population whose most severe complication is suicide.
- Trial name
- NCT03011190
- Testing
- Emotional regulation
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Silvia Elisa Hurtado Santiago
Borderline Personality Disorder (BPD), Dialectical Behavior Therapy
Effectiveness of Enhanced Dialectical Behavior Therapy Skills Training Group for Borderline Personality Disorder
Dialectical Behavior Therapy (DBT) holds the strongest empirical support for the treatment of Borderline Personality Disorder (BPD).
- Conditions
- Borderline Personality Disorder (BPD), Dialectical Behavior Therapy, Public Health, Suicide Behavior
- Trial name
- ANDES (NCT07875166)
- Testing
- Enhanced Dialectical Behavior Therapy Skills Training, Dialectical Behavior Therapy, Treatment as Usual (TAU)
- Where
- 7 sites in Chile
- Volunteers
- 360 people
- Sponsor
- Hospital Dr Sotero del Rio
Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD)
Study of Emotional Dysregulation in Complex Post-Traumatic Stress Disorder
This study aims to characterize emotional dysregulation in complex post-traumatic stress disorder (cPTSD) and to determine the extent to which it can promote the distinction with borderline personality disorder (BPD) and…
- Conditions
- Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD), Post-traumatic Stress Disorder (PTSD)
- Trial name
- TR-EMA (NCT06848127)
- Testing
- Self-questionnaires, Cognitive assessment, Momentary Ecological Assessment (EMA)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Borderline Personality Disorder (BPD), Avoidant Personality Disorders
Physical Activity in the Management of Personality Disorders
The PANDA trial is studying whether two types of physical activity - a walking program and supervised karate training - are safe, acceptable, and possible for adults with certain personality disorders.
- Trial name
- PANDA (NCT07341438)
- Testing
- Karate, Pedometer-based walking, Treatment as usual (TAU)
- Where
- 2 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Julie Midtgaard