Clinical trials: Borderline Personality Disorders, open to volunteers
Borderline Personality Disorder (BPD)
Application and Effectiveness of the STEPPS in Patients with BPD, Extending to Their Families with the FC Program
The present research project is framed within the issue of Borderline Personality Disorder (BPD). This condition stands as one of the most common challenges encountered within the mental health services of the National Health…
- Trial name
- NCT06195553
- Testing
- STEPPS plus Family Connections, STEPPS
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Universitat Jaume I
Borderline Personality Disorder, Borderline Personality Pathology
ADEPT Psilocybin-Assisted Therapy With DBT for Borderline Personality Disorder
ADEPT is an open-label proof-of-concept study evaluating the safety and tolerability of psilocybin-assisted therapy in conjunction with Dialectical Behavior Therapy for participants with borderline personality disorder.
- Conditions
- Borderline Personality Disorder, Borderline Personality Pathology, Depressive Symptoms, Emotion Dysregulation
- Trial name
- ADEPT (NCT07833761)
- Testing
- Psilocybin, Psilocybin-Assisted Therapy With Dialectical Behavior Therapy
- Where
- 2 sites in United States
- Volunteers
- 18 people
- Sponsor
- University of Minnesota
Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group, Diagnosis of ADHD Using the KSADS-PL for the ADHD Group
ADOLESCENTS IMAGING USING fMRI: Feasibility Study
Impaired social cognition and cognitive control associated with borderline personality disorder (BPD) remain less explored. Recent Franco-Canadian study, has shown the feasibility of a neuroimaging tests in Quebec adolescents…
- Conditions
- Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group, Diagnosis of ADHD Using the KSADS-PL for the ADHD Group, Absence of Pathology on the CBCL and Ab-DIB for the Healthy Control Group, All Participants Were Euthymic at the Time of Task Administration
- Trial name
- ADO IMAGE (NCT07540429)
- Testing
- functional magnetic resonance imaging (fMRI)
- Where
- France
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Etablissement Public de la Sante Mentale de la Somme
Borderline Personality Disorder
The Influence of Treatment Format on Schema Therapy for Borderline Personality Disorder
The goal of this clinical trial is to compare etc. in patients with borderline personality disorder pure individual schema therapy to combined individual-group schema therapy.
- Trial name
- IST-IGST (NCT05986552)
- Testing
- Individual Schema Therapy (IST), Individual-Group Schema Therapy (IGST)
- Where
- 3 sites in Netherlands
- Volunteers
- 132 people
- Sponsor
- University of Amsterdam
Emotion Regulation, Mood Disorders
Neurostimulation Versus Therapy for Problems With Emotions
The primary goal of this clinical trial is to evaluate the unique neural and behavioral effects of a one-session training combining emotion regulation skills training, with excitatory repetitive transcranial magnetic stimulation…
- Conditions
- Emotion Regulation, Mood Disorders, Stress Disorder, Anxiety Disorders
- Trial name
- NCT05712057
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), electrical scalp stimulation, Cognitive Restructuring
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Duke University
Borderline Personality Disorder (BPD)
The Role of Gender in Borderline Personality Disorder
This study is a mixed-methods, single-arm cross-sectional study comprising 1) a qualitative, exploratory, critical-constructivist content analysis examining the significance of gender in relationship experiences and…
- Trial name
- BPD-G (NCT07639957)
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- University Hospital Heidelberg
Depressive Disorder, Major, Borderline Personality Disorder
Treatment of Acute Mood Depressive Episode in Borderline Personality Disorder With rTMS
This study evaluates the antidepressant effects of an accelerated schedule of theta-burst stimulation, termed accelerated intermittent theta-burst stimulation (aiTBS), in individuals with borderline personality disorder (BPD) or…
- Trial name
- NCT04870255
- Testing
- Left Dorsolateral Prefrontal Cortex (L-DLPFC), Dorsomedial Prefrontal Cortex (DMPFC)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Borderline Personality Disorder
Testing Interventions for Borderline Personality Disorder.
Borderline personality disorder (BPD) is a life-threatening, costly public health crisis affecting ~1-3% of North Americans, with 10% dying by suicide and annual healthcare costs of ~$63k (Canadian Dollars)/patient.
- Trial name
- NCT06458933
- Testing
- Sage, Supportive Individual Psychotherapy
- Where
- Canada
- Volunteers
- 304 people
- Sponsor
- York University
Borderline Personality Disorder
Effectiveness of EMDR in Borderline Personality Disorder
Borderline personality disorder (BPD) is a severe mental disorder characterized by four major symptomatological domains: interpersonal instability, perceptive and identity disorders, emotional and behavioural dysregulation.
- Trial name
- EMBODIER (NCT06493708)
- Testing
- Trauma focused psychotherapy: EMDR
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Borderline Personality Disorder
Acute Effects of Physical Exercise in Patients with Borderline Personality Disorder
The aim of the proposed project is to investigate the effects of a single session of physical exercise on stress regulation, cognitive and emotional functioning, and associated neurophysiological processes (saliva and blood…
- Trial name
- NCT05246527
- Testing
- Physical Exercise, Control Intervention
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Borderline Personality Disorder, Borderline Personality
Treatment of Borderline Personality Disorder With rTMS
This project studies the effectiveness of brain stimulation on borderline personality disorder (BPD) symptoms. This study is blinded, randomized and will enroll up to 30 participants.
- Conditions
- Borderline Personality Disorder, Borderline Personality, BPD - Borderline Personality Disorder
- Trial name
- ClinicalBPD (NCT07197502)
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of California, Los Angeles
Borderline Personality Disorder
Pilot Study on Auricular Acupuncture in Hospitalized Adults With Borderline Personality Disorder
The goal of this pilot study is to evaluate the feasibility and preliminary effectiveness of a brief auricular acupuncture program delivered by mental health nurses as a complementary therapy for adults hospitalized with…
- Trial name
- ACUPSY (NCT07476300)
- Testing
- Auricular acupuncture program based on the N.A.D.A. protocol
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- Jenny Gentizon
Borderline Personality Disorder (BPD)
A Pilot Trial of One-Day Accelerated TMS and D-cycloserine in Suicidal Patients With Borderline Personality Disorder
This study tests a new treatment for people with borderline personality disorder (BPD). The treatment combines a medication called D-cycloserine with one day of transcranial magnetic stimulation (TMS).
- Trial name
- ONE-D BPD (NCT07460947)
- Testing
- TMS, D-Cycloserine (DCS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mclean Hospital
Major Depressive Disorder, Borderline Personality Disorder
Triage Survey for Psychiatry Research Eligibility
TRIAGE-Psych is a survey study designed to assess potential participants' eligibility to screen for industry-sponsored psychiatry clinical trials.
- Conditions
- Major Depressive Disorder, Borderline Personality Disorder, Generalized Anxiety Disorder
- Trial name
- TRIAGE-Psych (NCT05800925)
- Testing
- Survey
- Where
- 6 sites in United States
- Volunteers
- 20,000 people
- Sponsor
- Adams Clinical
Borderline Personality Disorder (BPD)
Internal Family Systems Therapy for Borderline Personality Disorder
Borderline Personality Disorder (BPD) involves intense emotional ups and downs, unstable relationships, impulsivity, and a poor sense of self.
- Trial name
- IFS for BPD (NCT07342907)
- Testing
- Internal family systems therapy
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Waypoint Centre for Mental Health Care
Borderline Personality Disorder
NEUROIMAGING OF ADOLESCENT BORDERLINE PERSONALITY DISORDER WITH AND WITHOUT POST-TRAUMATIC STRESS DISORDER
Borderline personality disorder (BPD) is a common mental disorder in adolescents with significant individual and societal repercussions, characterized over the long term by emotional hyperresponsiveness, relational instability…
- Trial name
- BorderStress (NCT04852744)
- Testing
- Brain MRI
- Where
- France
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)
The goal of this clinical trial is to learn if intravenous (IV) ketamine with Dialectical Behavioural Therapy (DBT) reduces suicidal ideation in individuals with suicidality who have been diagnosed with Borderline Personality…
- Conditions
- Borderline Personality Disorder (BPD), Treatment-Resistant Major Depressive Disorder, Treatment-resistant Bipolar Depression, Major Depressive Disorder (MDD)
- Trial name
- KET-DBT (NCT07569198)
- Testing
- Ketamine Hydrochloride, Midazolam Hydrochloride, Dialectical Behavioral Therapy (DBT)
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Joshua Rosenblat
Borderline Personality Disorder
Mentalization-based Treatment Versus Bona-fide Treatment for Patients With Borderline Personality Disorder in Germany
Background: Borderline Personality Disorder (BPD) is a serious mental disorder. Mentalization-based treatment (MBT) is one evidence-based treatment for individuals with BPD.
- Trial name
- MAGNET (NCT06018272)
- Testing
- Mentalization-Based Treatment (MBT), Bona-Fide Treatment in Germany (BFT)
- Where
- 5 sites in Germany
- Volunteers
- 304 people
- Sponsor
- Heidelberg University
Treatment 1:Dialectical Behavior Therapy (DBT), Treatment as Usual
Efficacy of "DBT-LIVE", an Identity Skills Training Program, for Borderline Personality Disorder.
The main objective of this project is to adapt and evaluate the LIVE Skill module in the Spanish population. LIVE Skill is a psychological intervention protocol specifically designed to address identity disturbances in…
- Trial name
- NCT07684872
- Testing
- DBT LIVE, TAU
- Where
- Spain
- Volunteers
- 112 people
- Sponsor
- Universidad Europea de Valencia
Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD)
Study of Emotional Dysregulation in Complex Post-Traumatic Stress Disorder
This study aims to characterize emotional dysregulation in complex post-traumatic stress disorder (cPTSD) and to determine the extent to which it can promote the distinction with borderline personality disorder (BPD) and…
- Conditions
- Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD), Post-traumatic Stress Disorder (PTSD)
- Trial name
- TR-EMA (NCT06848127)
- Testing
- Self-questionnaires, Cognitive assessment, Momentary Ecological Assessment (EMA)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France