Clinical trials: Botulinum Toxin, Type A
Chronic Ulcer of Lower Extremity, Wound
Effect of Blood Flow by Botulinum Toxin Injection for Severe Peripheral Artery Occlusive Disease
The purpose of this study is to investigate the effect of subcutaneous injection of botulinum toxin A on wound healing caused by lower extremity ischemia.
- Conditions
- Chronic Ulcer of Lower Extremity, Wound, Botulinum Toxins, Type A, Blood Circulation
- Trial name
- NCT06878482
- Testing
- Botulinum toxin A
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Yonsei University
Chronic Disease, Nasal Polyposis
Botulinum Toxin Type A Block of the Sphenopalatine Ganglion in Chronic Rhinosinusitis With Nasal Polyposis
Chronic rhinosinusitis (CRS) with nasal polyps is a particularly challenging form of chronic rhinosinusitis in several ways. Patients have significantly more severe symptom burden and worse quality of life than patients with…
- Conditions
- Chronic Disease, Nasal Polyposis, Rhinitis
- Trial name
- NCT02784262
- Testing
- botox injection Multiguide
- Where
- Norway
- Volunteers
- 11 people
- Sponsor
- Norwegian University of Science and Technology
Healthy Volunteers
Botulism Antitoxin Effects on Paralysis Induced by Botulinum Neurotoxins in the EDB Muscle
The primary purpose of this study is: 1. To evaluate the model determined by the ability of botulism antitoxin (bivalent, Aventis) to neutralize Botulinum toxin in the Extensor Digitorum Brevis model of muscle paralysis in Stage…
- Trial name
- NCT00636519
- Testing
- Botulism Antitoxin Bivalent (Equine) Types A and B, Botulism Antitoxin Heptavalent (Equine) Types A-G
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Emergent BioSolutions
Spasticity, Post-Stroke
JCP Study of Investigation of Patient Background Characteristics
To collect the background characteristics of juvenile cerebral palsy patients aged 2-year or older prescribed BOTOX for the treatment of equines foot due to lower limb spasticity, compare them with those of patients whose deaths…
- Trial name
- NCT01332474
- Testing
- BOTOX
- Volunteers
- 326 people
- Sponsor
- GlaxoSmithKline
Glabellar Lines
Non-interventional Study, Long Term Treatment on Glabellar Lines With Dysport® in Subjects of Chinese Origin
This is a prospective, longitudinal, non-interventional, multi-center study to collect subject and physician satisfaction, and treatment experience with Dysport in real clinical practice in subjects of Chinese origin.
- Trial name
- NCT05089357
- Testing
- AbobotulinumtoxinA
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Galderma R&D
Cervical Dystonia
Post-marketing Surveillance of Administration of Botulinum Toxin Type B(NerBloc)-Investigation of the Clinical Condition and Safety in Patients With Cervical Dystonia
Investigation of the clinical condition and safety in patients with cervical dystonia
- Trial name
- NCT02175693
- Where
- 2 sites in Japan
- Volunteers
- 1,647 people
- Sponsor
- Eisai Co., Ltd.
Upper Limb Spasticity After Stroke
A Prospective, Non-interventional Survey to Evaluate Injection Intervals and Treatment Modalities of Botulinum Toxin A (BoNT-A) in Adult Patients Suffering From Upper Limb Spasticity After Stroke
The purpose of the protocol is to evaluate injection intervals and treatment modalities up to 3 years follow-up of botulinum toxin A (BoNT-A) in adult patients suffering from upper limb spasticity after stroke.
- Trial name
- DECIDE (NCT01239628)
- Where
- 11 sites in Belgium
- Volunteers
- 45 people
- Sponsor
- Ipsen
Anal Fissure
Comparison of Treatment Success of Botox Injection in the Internal Sphincter Versus Isosorbidedinitrate Ointment in Patients With an Anal Fissure
The standard treatment of anal fissure in the netherlands (ISDN ointment) is being compared to a relatively new treatment (injection of Botox in the internal anal sphincter).
- Trial name
- NCT00827736
- Testing
- Botox, ISDN ointment
- Where
- Netherlands
- Volunteers
- 73 people
- Sponsor
- Onze Lieve Vrouwe Gasthuis
Lateral Canthal Lines, Crow's Feet
Safety and Efficacy Study of RT001 to Treat Moderate to Severe Lateral Canthal Lines
The purpose of this study is to evaluate the safety and efficacy of RT001 to treat moderate to severe lateral canthal lines in adults.
- Conditions
- Lateral Canthal Lines, Crow's Feet, Facial Wrinkles
- Trial name
- NCT00888914
- Testing
- RT001, Vehicle Comparator
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Revance Therapeutics, Inc.
Erectile Dysfunction
Radiological Evaluation of the Penis Before and After a Botox Injection
The goal of this clinical trial is to find out if injecting Botox into men with erectile dysfunction makes their penis less stiff and gives them better erections. This will be done using a new ultrasound method.
- Trial name
- NCT06044883
- Testing
- Injection of Botulinum neurotoxin (BoNT), Penile duplex and shear wave elastosonography (SWE).
- Where
- Egypt
- Volunteers
- 32 people
- Sponsor
- Cairo University
Chronic Scar Pain
Dysport in Post-Surgical Neuralgia
The study is designed to determine whether a currently licensed version of botulinum toxin (Dysport®) is effective for the treatment of pain that has developed and/or persisted for months or years around the scar of a previous…
- Trial name
- PMOD03 (NCT03663101)
- Testing
- Lidocaine, Botulinum toxin type A
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Ipsen
Incisional Hernia
Botulinum Toxin A Facilitates Fascial Closure in Complex Incisional Hernias
Brief Study Description This prospective observational study evaluates the use of preoperative botulinum toxin A as part of a structured clinical pathway for patients undergoing elective repair of complex midline incisional…
- Trial name
- BRIDGE-HERNIA (NCT07349628)
- Where
- Italy
- Volunteers
- 32 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Overactive Bladder
Instillation of Botox in the Bladder in Women With Overactive Bladder (OAB)
Instillation treatment with onabotulinumtoxin A (BOTOX®) in the urinary bladder
- Trial name
- NCT02735499
- Testing
- onabotulinum toxin A
- Where
- Norway
- Volunteers
- 14 people
- Sponsor
- The Hospital of Vestfold
Low Back Pain
Pilot Study to Assess the Efficacy of Botulinum Toxin A Treatments on Pain and Disability in Sub-Acute Low Back Pain
This study will test the hypothesis that Botulinum toxin A (BOTOX®) treatment reduces pain and disability in subjects suffering from sub-acute low back pain due to an identifiable muscle strain or back trauma occurring 6 to 16…
- Trial name
- NCT00384371
- Testing
- Botulinum Toxin A
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- United States Department of Defense
Lateral Canthus Rhytides, Crow's Feet Lines
Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Crow's Feet Lines
This study will evaluate the safety and efficacy of botulinum toxin Type A compared to placebo for the treatment of Crow's Feet Lines (Lateral Canthal Rhytides).
- Trial name
- NCT01189747
- Testing
- onabotulinumtoxinA, normal saline
- Where
- 4 sites in United States, Belgium and 2 more
- Volunteers
- 446 people
- Sponsor
- Allergan
TMJ Disc Disorder, TMJ Pain
I-PRF After Arthrocentesis Plus Botox Injection to Lateral Pterygoid Muscle in Treatment of Anterior Disc Displacement
Aim of Study : To evaluate the efficacy of TMJ arhtrocentesis followed by injection of liquid platelet rich fibrin (I-PRF ) in addition to intramuscular injection of lateral pterygoid muscle with botulinum toxin on clinical…
- Trial name
- NCT06207955
- Testing
- TMJ Arthrocentesis Followed By Injectable Platelet Rich Fibrin And Botulinum Toxin Type A, TMJ Arthrocentesis Followed By Injectable Platelet Rich Fibrin, TMJ Arthrocentesis
- Where
- Egypt
- Volunteers
- 39 people
- Sponsor
- Fayoum University
Migraine Disorders
A Long-term Efficacy, Safety, and Tolerability Study of BOTOX® in Patients With Chronic Migraine
This open-label study will assess the long-term efficacy, safety, and tolerability of onabotulinumtoxinA administered for prophylaxis of headaches in patients with chronic migraine.
- Trial name
- NCT01516892
- Testing
- onabotulinumtoxinA
- Where
- 32 sites in United States, Australia and 1 more
- Volunteers
- 716 people
- Sponsor
- Allergan
Chronic Migraine Headache
Effectiveness of Greater Occipital Nerve and Supratrochlear Nerve Pulsed Radiofrequency Versus Botulinum Toxin Type A Injection in Chronic Migraine
Migraine is a common chronic neurovascular disorder ranked among the leading causes of disability worldwide, and its global burden has continued to rise over the past three decades, with prevalence increasing substantially…
- Trial name
- NCT07780136
- Testing
- Ultrasound-guided pulsed radiofrequency (PRF), OnabotulinumtoxinA
- Volunteers
- 70 people
- Sponsor
- Assiut University
Facial Rhytides, Glabellar Frown Lines
Safety and Efficacy Study of Botulinum Toxin Type A for the Treatment of Forehead and Frown Lines
This study evaluated the safety and efficacy of botulinum toxin Type A compared to placebo for the treatment of forehead lines (facial rhytides) when also administered to frown lines (glabellar rhytides).
- Trial name
- NCT01391299
- Testing
- botulinum toxin Type A, Normal Saline
- Where
- Canada
- Volunteers
- 175 people
- Sponsor
- Allergan
Erectile Dysfunction
Intracavernous Injection of Botox 100 U for Treatment of PDE5Is Inconvenient Patients With ED
There is a new emerging concept that Botulinum Toxin Type A may have a potential role in treatment of erectile dysfunction with a longer duration of action.
- Trial name
- NCT04172558
- Testing
- OnabotulinumtoxinA, Trimix
- Where
- Egypt
- Volunteers
- 124 people
- Sponsor
- Benha University