Clinical trials: Botulinum Toxin, Type A
Glabellar Lines
A Study Of BOTOX For The Treatment Of Glabellar Lines
This is a Multicenter, double-blind, randomized, placebo-controlled, parallel-group comparative study to confirm the efficacy and safety of BOTOX 20 units single injection for the Chinese patients with glabellar lines.
- Trial name
- NCT00408785
- Testing
- Botulinum Toxin Type A, sodium chloride
- Where
- 4 sites in China
- Volunteers
- 256 people
- Sponsor
- GlaxoSmithKline
Overactive Bladder, Urinary Incontinence
Long Term Follow-up Study of Safety and Efficacy of Botulinum Toxin Type A for the Treatment of Patients With Idiopathic Overactive Bladder With Urinary Incontinence
The purpose of this study is to assess the long term safety and effectiveness of botulinum toxin type A in treating patients with idiopathic overactive bladder with urinary incontinence.
- Trial name
- NCT00915525
- Testing
- botulinum toxin Type A
- Where
- 8 sites in United States, Belgium and 6 more
- Volunteers
- 829 people
- Sponsor
- Allergan
Facial Rhytides
A Study of Subject Satisfaction With BOTOX® Cosmetic Treatment in Facial Rhytides
This is a safety and efficacy study of BOTOX® in subjects with facial rhytides (glabellar lines and crow's feet lines).
- Trial name
- NCT01777620
- Testing
- onabotulinumtoxinA, Normal Saline
- Where
- Canada
- Volunteers
- 125 people
- Sponsor
- Allergan
Skin Aging
Efficacy and Safety of Botulinum Toxin Type A for Moderate to Severe Crow's Feet Lines
This study will confirm the efficacy and safety of a single topical administration of botulinum toxin type A compared to placebo control for the treatment of moderate to severe crow's feet lines
- Trial name
- NCT01940991
- Testing
- Botulinum Toxin Type A
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Revance Therapeutics, Inc.
Pain
Assessing the Efficacy of Virtual Reality Analgesia (VRA) in Pediatric Patients for Pain Control
To evaluate the efficacy of virtual reality analgesia (VRA) for pediatric patients undergoing Botulinum toxin injections (BTI) for spasticity management.
- Trial name
- PEDSPAINVR (NCT03480724)
- Testing
- Google Cardboard VRA, Oculus Rift VRA
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Montefiore Medical Center
Cerebrovascular Accident
A Study to Evaluate the Botulinum Toxin Type A for Injection(HengLi®) in Subjects With Post-stroke Upper Limb Spasticity
This is a multicenter, double-blind, randomized, placebo-controlled study designed to compare Botulinum Toxin Type A for Injection (HengLi®) with placebo on the efficacy and safety of treatment in post-stroke subjects with focal…
- Trial name
- NCT02280083
- Testing
- Botulinum Toxin Type A for Injection
- Volunteers
- 180 people
- Sponsor
- Lanzhou Institute of Biological Products Co., Ltd
Post Traumatic Stiffness
Botulinum Toxin as a Novel Treatment for Prevention of Post-Traumatic Elbow Stiffness
This is a randomized double blind placebo controlled study to investigate the hypothesis that injection of botulinum toxin A into the muscles surrounding the elbow following the surgical treatment of an elbow fracture will reduce…
- Trial name
- NCT01129583
- Testing
- Botulinum Toxin Type A, Saline
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Columbia University
Low Anterior Resection Syndrome (LARS>20), Refractory Medical Treatment After Rectal Resection
A Prospective Pilot Study to Assess the Efficacy of BOTOX-A in Patients With Low Anterior Resection Syndrome (LARS>20) and Refractory Medical Treatment After Rectal Resection
After rectal resection for cancer (with or without stoma), patients may have digestive sequelae. LARS (Low Anterior Resection Syndrome) includes bowel frequency, stool fragmentation, urgency, and faecal incontinence.
- Trial name
- BOTOX-TME (NCT04991688)
- Testing
- BOTOX-A
- Where
- France
- Volunteers
- 11 people
- Sponsor
- University Hospital, Bordeaux
Botulinum Toxin Type A, Rives Repair
Botulinum Toxin to Avoid Component Separation in Midline Large Hernias
Introduction. The goal of our study was to compare results in patients with large midline incisional hernia (LMIH) using only anterior compònent separation (CST) versus preoperative botulinum toxin (BT) and following Rives repair…
- Conditions
- Botulinum Toxin Type A, Rives Repair, Large Midline Hernia, Component Separation
- Trial name
- BTCS01 (NCT04131348)
- Testing
- botulinum toxin type A
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital Universitario La Fe
Cerebrovascular Accident, Stroke
Spastic Cocontractions and Limitation of Active Movements Before and After Treatment During Injection of Botulinum Toxin
Following a stroke , 55% of the patients do not recover any traction of the upper limb and 30% a residual motricity not allowing a functional grip.
- Trial name
- NCT03453008
- Testing
- elbow extension, electromyography
- Where
- France
- Volunteers
- 14 people
- Sponsor
- University Hospital, Toulouse
Upper Limb Spasticity
A Clinical Study on Recombinant Botulinum Toxin Type A (YY001) for Injection in The Treatment of Upper Limb Spasticity in Adults
This is a randomized, double-blind, multi-center phase II/III study to evaluate the efficacy and safety of Recombinant Botulinum Toxin Type A (YY001) for injection in the treatment of upper limb spasticity in adults
- Trial name
- NCT06783114
- Testing
- Recombinant Botulinum Toxin Type A for injection (YY001), BOTOX®
- Where
- 24 sites in China
- Volunteers
- 254 people
- Sponsor
- Chongqing Claruvis Pharmaceutical Co., Ltd.
Overactive Bladder, Urinary Tract Infections
Comparison of Methods for Prevention of Urinary Tract Infection Following Botox Injection
Injection of OnabotulinumtoxinA (BTX-A) into the bladder is a widely used treatment option for patients with overactive bladder who have failed medical therapy.
- Trial name
- NCT03508921
- Testing
- Periprocedural Antibiotics, Extended Antibiotics, Injection of OnabotulinumtoxinA (BTX-A)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Vanderbilt University Medical Center
Muscle Spasticity, Cerebrovascular Accident
Asian Botulinum Clinical Trial Designed for Early Stroke Spasticity
The aim of this clinical study is to investigate the efficacy and safety of Dysport® in patients with early onset of upper limb spasticity within 2-12 weeks after stroke.
- Trial name
- NCT00234546
- Testing
- Botulinum toxin type A
- Where
- 5 sites in Hong Kong, Malaysia and 3 more
- Volunteers
- 162 people
- Sponsor
- Ipsen
Chronic Pain, Lower Extremity Wound
The Effect of Subcutaneous Injection of Botulinum Toxin A on Chronic Wound Pain in Lower Extremities
The aim of the study is to investigate the effect of subcutaneous administration of Botulinum toxin A on wound pain, wound healing and safety of treatment.
- Trial name
- NCT05426161
- Testing
- Botulinum Toxin A
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Bispebjerg Hospital
Male Pattern Baldness
Treatment of Male Pattern Baldness With Botulinum Toxin
This proof of concept study seeks to demonstrate that Botulinum toxin injections are a safe and effective method for treating this form of hair loss.
- Trial name
- NCT00965640
- Testing
- Botulinum Toxin - A injections
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Crown Institute
Gummy Smile Due to Hypermobile Upper Lip
Effect of Cross-linked Hyaluronic Acid Filler Versus Botulinum Toxin Type A (Botox) in Management of Gummy Smile
A smile is supposed to express one's feelings and expressions, for that there has been an awakening concern for the appearance of gummy smile. Gummy smile is the appearance of about 2mm or more of the gingiva during smiling.
- Trial name
- NCT06952218
- Testing
- Injection of cross linked hyaluronic acid filler
- Where
- 2 sites in Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Trigeminal Neuralgia
Safety and Efficacy of Botulinum Toxin A in Patients With Trigeminal Neuralgia
This is a double-blind randomized clinical trial comparing the pain reduction of individuals treated with BTX-A and placebo as well as evaluating possible changes in neuroinflammatory biomarkers.
- Trial name
- NCT06315790
- Testing
- Botulinum toxin A, Isotonic saline
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- Henrik Schytz
Focal Dystonia
Quantifying Musical Performance After Treatment With Myobloc in Musician's Dystonia
This study uses a computerized method of musical instrument digital interface (MIDI) quantification of performance before and after treatment with botulinum toxin type B (Myobloc ®, Solstice Neurosciences).
- Trial name
- NCT00208091
- Testing
- Botulinum toxin, type B
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Columbia University
Acne Vulgaris
Clinical Trial To Evaluate ANT-1207 In Subjects With Acne
The purpose of this study is to provide evidence of the safety, tolerance, and efficacy of ANT-1207 in the treatment of acne.
- Trial name
- NCT01293552
- Testing
- ANT-1207, Vehicle
- Where
- 15 sites in United States
- Volunteers
- 72 people
- Sponsor
- Anterios Inc.
Glabellar Lines
A Study to Evaluate Sequential Administration of AGN-151586 and OnabotulinumtoxinA (BOTOX) Injections in Adult Participants for Treatment of Glabellar Lines
Facial lines that develop from repeated facial expression, such as glabellar lines (GL), are typically treated by selectively weakening specific muscles with small quantities of botulinum toxin.
- Trial name
- NCT05496335
- Testing
- AGN-151586, BOTOX
- Where
- 10 sites in United States
- Volunteers
- 90 people
- Sponsor
- AbbVie