Clinical trials: Botulinum Toxins, Type A
Hypertrophic Scar
Treatment of Hypertrophic Scars With Intradermal Botox
This is a prospective, open label, single center, self-controlled clinical study to demonstrate the safety and efficacy of intradermal botulinum toxin in treating hypertrophic scarring.
- Trial name
- NCT03631368
- Testing
- Botox
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Roy G. Geronemus, M.D.
Hyperhidrosis, Residual Limbs
Topical Aluminium Chloride vs OnabotulinumtoxinA Intradermal Injections in Residual Limb Hyperhidrosis (Lower Limbs)
The aim of this study is to demonstrate onabotulinumtoxinA superiority to aluminium chloride for the treatment of residual limb hyperhidrosis.
- Trial name
- SALUTOX (NCT03433859)
- Testing
- OnabotulinumtoxinA, Topical Aluminium Chloride (cosmetic product)
- Where
- 9 sites in France
- Volunteers
- 54 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Torticollis
A Prospective, Observational Study of Patients With Cervical Dystonia (Dystonie) Treated With OnabotulinumtoxinA
This is an observational study to assess health-related quality of life in patients with cervical dystonia (dystonie) treated with OnabotulinumtoxinA per routine clinical practice.
- Trial name
- NCT01655862
- Testing
- OnabotulinumtoxinA
- Where
- 8 sites in Canada
- Volunteers
- 62 people
- Sponsor
- Allergan
Glabellar Rhytides
Treatment With Botulinum Toxin Type A (BOTOX®) in Chinese Patients With Moderate to Severe Frown Lines
A study to evaluate safety and efficacy of treatment with botulinum toxin Type A (BOTOX®) in Chinese patients with moderate to severe frown lines (Glabellar Rhytides) previously treated with facial laser resurfacing.
- Trial name
- NCT01814670
- Testing
- botulinum toxin Type A
- Where
- China
- Volunteers
- 185 people
- Sponsor
- Allergan
Glabellar Lines
To Compare the Safety and Efficacy of "HG-102" With Botox® in the Improvement of Moderate to Severe Glabellar Lines.
To compare the safety and efficacy of "HG-102" with Botox® in the improvement of moderate to severe glabellar lines.
- Trial name
- NCT04944953
- Testing
- Botulinum Toxin Type A Injection [Botox], Botulinum toxin type A injection [HG-102]
- Where
- South Korea
- Volunteers
- 38 people
- Sponsor
- Hugel
Trigeminal Neuralgia
Botulinum Toxin Type A for Injection (HengLi®) in the Treatment of Trigeminal Neuralgia
To evaluate the efficacy of different dosing regimens of Botulinum Toxin Type A for Injection (HengLi®) in the treatment of trigeminal neuralgia (TN), so as to determine the optimal dosing regimen of the best administration…
- Trial name
- NCT06410859
- Testing
- Botulinum Toxin Type A for Injection,also known as "HengLi®"
- Where
- China
- Volunteers
- 240 people
- Sponsor
- LKGS_277
Healthy
Functional Effects of Botox on the Brain Using MRS and fMRI
The injection of BOTOX into peripheral muscles has been shown to have therapeutic effects in a growing number of indications including disorders involving skeletal muscle (e.g., strabismus, blepharospasm, cervical dystonia…
- Trial name
- NCT03373162
- Testing
- onabotulinumtoxinA
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Muscle Spasticity
BOTOX® Treatment in Adult Patients With Post-Stroke Lower Limb Spasticity
This study will evaluate the safety and efficacy of BOTOX® in the treatment of adult post-stroke lower limb spasticity.
- Trial name
- NCT01575054
- Testing
- botulinum toxin Type A, Normal Saline
- Where
- 12 sites in United States, Canada and 7 more
- Volunteers
- 468 people
- Sponsor
- Allergan
Facial Pain
Botox Injections for Patients With Persistent Facial Pain
The main objective of this study is to investigate efficacy and safety of injecting botulinum toxin towards the sphenopalatine ganglion using MultiGuide in patients with persistent idiopathic facial pain
- Trial name
- NCT03462290
- Testing
- botulinum toxin type A
- Where
- Norway
- Volunteers
- 31 people
- Sponsor
- Norwegian University of Science and Technology
Smiling, Botulinum Toxins, Type A
Higher Doses of Botulinum Toxin in the Treatment of Gummy Smile
Botulinum type A (BTX-A) is an easy and efficacious treatment for gingival smile (GS). However, the necessary for higher-doses among patients are controversial.
- Trial name
- NCT05127018
- Testing
- injection of Botulinum type A
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Peking University
Brow Ptosis, Lid Ptosis
Brow Lifting With Dysport
The purpose of this study is to provide data to assess Dysport™ injections as a treatment therapy for brow ptosis. This study will assess the outcome of brow lifting with use of Dysport.
- Trial name
- NCT01401803
- Testing
- Dysport
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Kenneth Beer
Upper Facial Lines (Glabellar Lines, Forehead Lines, & Lateral Canthal Lines)
Efficacy and Safety of DaxibotulinumtoxinA (DAXI) for Injection for Treatment of Upper Facial Lines
This is a Phase 2, multicenter, open-label, single-arm study to evaluate the efficacy and safety of DaxibotulinumtoxinA for injection (DAXI for injection) in the treatment of Glabellar Lines (GL), Dynamic Forehead Lines (FHL)…
- Trial name
- NCT04259086
- Testing
- DaxibotulinumtoxinA for injection
- Where
- 8 sites in United States, Canada
- Volunteers
- 48 people
- Sponsor
- Revance Therapeutics, Inc.
Glabellar Lines
Evaluate the Safety and Efficacy of HG102 as Compared to Botox® in Subject With Moderate to Severe Glabellar Lines
To evaluate the efficacy and safety of HG102 for moderate to severe Glabellar Lines, non-inferiority compared to Botox® was confirmed and safety was evaluated.
- Trial name
- NCT05801146
- Testing
- Botulinum Toxin Type A Injection [HG102], Botulinum Toxin Type A Injection [Botox]
- Where
- South Korea
- Volunteers
- 272 people
- Sponsor
- Hugel
Stroke, Muscle Spasticity
Safety Study of Botulinum Toxin Type A for the Treatment of Focal Upper Limb Poststroke Spasticity
The purpose of this study is to evaluate the safety of repeated doses of Botulinum Toxin Type A for the treatment of focal upper limb poststroke spasticity
- Trial name
- NCT00651729
- Testing
- Botulinum Toxin Type A
- Where
- 2 sites in United States, Canada
- Volunteers
- 279 people
- Sponsor
- Allergan
Interstitial Cystitis
Efficacy of Botulinum Toxin Type A in Patients With Bladder Pain Syndrome/Intersticial Cystitis and Hunners' Lesions
The etiology of bladder pain syndrome is unknown. Therefore the management is directed to pain relief, as bladder pain is believed to drive both voiding frequency and nocturia.
- Trial name
- NCT01437579
- Testing
- intratrigonal injection of botulinum toxin, cystoscopy
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Moscow State University of Medicine and Dentistry
Blepharospasm, Hemifacial Spasm
Testing the Effect of Zinc Supplementation to Improve the Treatment Effect of Botulinum Toxin for Oculofacial Spasm
The purpose of this study is to determine whether zinc supplements are effective in enhancing the treatment of oculofacial spasm disorders with botulinum toxin.
- Trial name
- NCT01546805
- Testing
- Zinc Supplement, Sugar pill
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Depression, Quality of Life
Quality of Life and Self-esteem After Botox® Injections in Depressed and Non-depressed Patients
The primary objective of this study is to determine the alterations in quality of life and self-esteem after BOTOX® injections in the glabella in depressed and non-depressed patients.
- Trial name
- NCT01004042
- Testing
- Botulinum Toxin Type A
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hexsel Dermatology Clinic
Alopecia Areata
The Comparison Study of Intralesional Botulinum Toxin A and Corticosteroid Injection for Alopecia Areata
Alopecia areata is one of the most common cause of non-scarring alopecia. The pathogenesis is still unclear, however, it is believed to be an autoimmune disease.
- Trial name
- NCT00999869
- Testing
- Botulinum toxin type A, Triamcinolone acetonide
- Where
- 2 sites in Thailand
- Volunteers
- 20 people
- Sponsor
- Siriraj Hospital
Glabellar Frown Lines
Efficacy and Safety of Botulinum Toxin at Moderate to Severe Glabellar Lines
Efficacy and safety of ATGC-100 are assessed in subjects with moderate to severe glabellar lines.
- Trial name
- NCT04830345
- Testing
- ATGC-100 100U, Botox 100U
- Where
- South Korea
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- EuBiologics Co.,Ltd
Tourette Syndrome, Chronic Vocal Tic
Pilot Study for Use of Dysport in Treatment of Vocal Tics in Patients With Tourette's Syndrome
Our intervention will be the injection of Abobotulinum toxin A into the affected site/vocal cords for patients with the diagnosis of Primary Tourette's syndrome.
- Trial name
- NCT02187679
- Testing
- Abobotulinum toxin A
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Detroit Clinical Research Center
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