Clinical trials: Botulism
Botulism
Pilot Study on the Usefulness of 3,4-diaminopyridine in the Treatment of Botulism
Main objectives: Evaluate the effectiveness of an administration of 3,4-diaminopyridine (FIRDAPSE ®) in severe botulinic poisoning in measuring the effect on electrophysiological and respiratory parameters Secondary Objective…
- Trial name
- NCT01441557
- Testing
- 3,4-diaminopyridine
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Botulism
Tolerability and Immunogenicity of rBV A/B for the Production of BabyBIG®
This Phase 2, open-label, uncontrolled study designed to evaluate safety, tolerability, and immunogenicity of a single dose of rBV A/B in healthy participants previously immunized with pentavalent botulinum toxoid (or pentavalent…
- Trial name
- NCT03676634
- Testing
- rBV A/B
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- California Department of Public Health
Botulism, Iatrogenic Botulism
Effect of Amifampridine on Neuromuscular Transmission in Patients Treated With OnabotulinumtoxinA
if amifampridine can improve neuromuscular transmission in muscles previously injected with OnabotulinumtoxinA (BTX-A)
- Trial name
- NCT05769478
- Testing
- Amifampridine
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Wake Forest University Health Sciences
Hailey-Hailey Disease, Darier Disease
Evaluation of the Improvement of Quality of Life of Patients Suffering From Hailey Hailey or Darier Disease After Injections of Botulism Toxin Into Large Folds.
Hailey Hailey and Darier disease are rare genetic dermatoses. Mutations of 2 genes (ATP2C1 or ATP2A2 respectively) are responsible for the diseases.
- Trial name
- ToxHD (NCT02782702)
- Testing
- Botulism Toxin Treatment
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse