Clinical trials: Bowel; Functional Syndrome
Self-hypnosis, Functional Bowel Disorder
Hypnotherapy With Audiofiles for Children and Adolescents With Disorders of Gut-brain Interactions in Sweden -a Feasibility Study
This study aims at testing the effect and feasibility of a new treatment strategy - hypnotherapy mediated with audio files - for children and adolescents with disorders of gut-brain-interaction (DGBI) in Sweden.
- Conditions
- Self-hypnosis, Functional Bowel Disorder, Functional Abdominal Pain Syndrome
- Trial name
- NCT06493097
- Testing
- Gut-directed hypnotherapy via audio files
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Karolinska Institutet
Irritable Bowel Syndrome, Dyspepsia
Functional Digestive Disorders Observatory
Functional digestive pathologies are defined by symptoms such as functional dyspepsia, gastroesophageal reflux, irritable bowel syndrome, gastroesophageal reflux, functional constipation, functional diarrhea, functional bloating…
- Conditions
- Irritable Bowel Syndrome, Dyspepsia, Functional Constipation, Faecal Incontinence
- Trial name
- OTFI (NCT04918329)
- Testing
- Observational study
- Where
- France
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Rouen
Chronic Pancreatitis, Inflammatory Bowel Diseases
Genomic Resources for Enhancing Available Therapies (GREAT1.0) Study
This is a prospective, descriptive, observational research study designed to observe and document the clinical practice by domain experts, and how the knowledge of new findings that are published in the medical literature affect…
- Conditions
- Chronic Pancreatitis, Inflammatory Bowel Diseases, Hepatitis, NASH - Nonalcoholic Steatohepatitis
- Trial name
- GREAT1 (NCT04306939)
- Testing
- venipuncture, Questionnaires, Additional Sample Collections
- Where
- United States
- Volunteers
- 120,000 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Irritable Bowel Syndrome With Constipation, Functional Constipation
Long-term Safety of Linaclotide in Pediatric Participants With FC or IBS-C
LIN-MD-66 is a Phase 3 open-label study with 24 weeks (Functional Constipation participants) or 52 weeks (Irritable bowel syndrome with constipation participants) of linaclotide exposure that will enroll pediatric participants…
- Trial name
- NCT04166058
- Testing
- Irritable Bowel Syndrome with Constipation (IBS-C) participants (LIN-MD-63 and LIN-MD-64 completers), Functional Constipation (FC) participants (LIN-MD-62 and LIN-MD-64 completers)
- Where
- 72 sites in United States, Canada and 2 more
- Volunteers
- 381 people
- Sponsor
- AbbVie
Irritable Bowel Disease, Functional Abdominal Pain - Not Otherwise Specified (FAP-NOS)
Pain in Pediatric Patients - Internet Interventions for Disorders of Gut-brain Interaction
Many children and adolescents often experience long-lasting stomach pain. In many cases, this is due to disorders of gut-brain interaction (DGBI), such as irritable bowel syndrome (IBS), functional abdominal pain, and functional…
- Conditions
- Irritable Bowel Disease, Functional Abdominal Pain - Not Otherwise Specified (FAP-NOS), Functional Dyspepsia
- Trial name
- PIPPI (NCT07319078)
- Testing
- Gut-directed hypnotherapy, Cognitive-behavioral therapy
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
Functional Abdominal Pain Disorders, Irritable Bowel Syndrome (IBS)
Efficacy of Guided Imagery Therapy Mobile Application for Functional Abdominal Pain
Chronic abdominal pain is common among children, and the majority of cases are attributed to functional abdominal pain disorders. One approach to treating these disorders is by using psychological therapies.
- Conditions
- Functional Abdominal Pain Disorders, Irritable Bowel Syndrome (IBS), Functional Gastrointestinal Disorders, Functional Colonic Disease
- Trial name
- NCT06653647
- Testing
- Guided Imagery Therapy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Baylor College of Medicine
Clostridium Difficile Infection Recurrence, Ulcerative Colitis (UC)
Real-World Study on Fecal Microbiota Transplantation: Long-Term Effectiveness and Safety Statistics
This is a large-scale observational study aiming to evaluate the long-term effectiveness and safety of Fecal Microbiota Transplantation (FMT).
- Conditions
- Clostridium Difficile Infection Recurrence, Ulcerative Colitis (UC), Crohn Disease (CD), Irritable Bowel Syndrome (IBS)
- Trial name
- NCT07261826
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Chen QiYi
Irritable Bowel Syndrome, Dyspepsia
Treatment of Functional Abdominal Distension by Non-instrumental Biofeedback
Background. Abdominal distention is produced by an abnormal somatic postural tone. The authors developed an original biofeedback technique based on electromyography-guided control of abdominothoracic muscular activity.
- Conditions
- Irritable Bowel Syndrome, Dyspepsia, Functional Bloating
- Trial name
- NCT06150638
- Testing
- Biofeedback
- Where
- Spain
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Irritable Bowel Syndrome, Repetitive Transcranial Magnetic Stimulation
Repetitive Transcranial Magnetic Stimulation Attenuates Visceral Pain in Irritable Bowel Syndrome With Diarrhea
Objective: To identify a central hub of visceral pain in IBS-D and elucidate the mechanism by which repetitive transcranial magnetic stimulation (rTMS) confers analgesic effects.
- Conditions
- Irritable Bowel Syndrome, Repetitive Transcranial Magnetic Stimulation, Chronic Visceral Pain, Functional Magnetic Resonance Imaging
- Trial name
- rTMS (NCT06409078)
- Testing
- rTMS group
- Where
- China
- Volunteers
- 42 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Functional Bowel Disorder, Irritable Bowel Syndrome
The 5Ad Diet for Functional Bowel Disorders
The goal of this randomised controlled trial (RCT) is to compare the efficacy of the newly developed 5Ad diet against the widely researched low fermentable oligo-, di-, monosaccharide and polyols (FODMAP) diet in reducing…
- Conditions
- Functional Bowel Disorder, Irritable Bowel Syndrome, Food Intolerance, Food Intolerance Syndromes
- Trial name
- NCT06338189
- Testing
- The 5Ad Diet, The Low FODMAP Diet
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Suffolk
Repetitive Transcranial Magnetic Stimulation, Chronic Visceral Pain
Lf-rTMS Attenuates Visceral Pain in Irritable Bowel Syndrome With Diarrhea
Objectives: To identify a central hub of visceral pain in IBS-D and elucidate the mechanism by which repetitive transcranial magnetic stimulation (rTMS) confers analgesic effects.
- Conditions
- Repetitive Transcranial Magnetic Stimulation, Chronic Visceral Pain, Functional Magnetic Resonance Imaging, IBS (Irritable Bowel Syndrome)
- Trial name
- NCT06757491
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 42 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Irritable Bowel Syndrome, Dyspepsia
Visible Abdominal Distension
Background. Abdominal distention is produced by an abnormal somatic postural tone. The authors developed an original biofeedback technique.
- Conditions
- Irritable Bowel Syndrome, Dyspepsia, Functional Bloating
- Trial name
- NCT06369753
- Testing
- Biofeedback
- Where
- 7 sites in United States, Canada and 5 more
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Functional Abdominal Pain Disorder
Low-FODMAP Diet for Functional Abdominal Pain Disorders in Children.
This single-center, randomized, controlled, quadruple-blinded, superiority trial is performed to test the hypothesis that children with IBS and FAP-NOS who receive a low-FODMAP diet will have a lower mean abdominal pain intensity…
- Trial name
- NCT04528914
- Testing
- Low-FODMAP diet
- Where
- Poland
- Volunteers
- 42 people
- Sponsor
- Medical University of Warsaw
Functional Gastrointestinal Disorders
Glucomannan for the Treatment of Abdominal Pain-related Functional Gastrointestinal Disorders in Childhood
Background: Functional abdominal pain disorders (FAPD) are common in school-aged children; however, there is no reliable treatment. Aim: To determine the efficacy and safety of glucomannan for treating FAPD in children.
- Trial name
- NCT01495806
- Testing
- Glucomannan
- Where
- Poland
- Volunteers
- 89 people
- Sponsor
- Medical University of Warsaw
Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome
Peppermint Oil for the Treatment of Irritable Bowel Syndrome or Functional Abdominal Pain in Children: the MINT Study
Peppermint oil has shown to be effective in the treatment of Irritable Bowel Syndrome (IBS) symptoms in adults. Few studies of low quality are performed in an paediatric setting.
- Conditions
- Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome, Child, Adolescent
- Trial name
- MINT (NCT05799053)
- Testing
- Small intestinal release peppermint oil, Peppermint sweets
- Where
- 3 sites in Netherlands
- Volunteers
- 228 people
- Sponsor
- St. Antonius Hospital
Functional Abdominal Pain Syndrome, Functional Gastrointestinal Disorders
i-CBT Functional Gastrointestinal Disorders in Youth: the Impact of Negative Illness Understanding and Parental Illness Worries
The aim of the current study, embedded in The Danish FGID Treatment Study, is to test Danish versions of Swedish i-CBT programs for children and adolescents with FGID in a Danish clinical context and to further evaluate the…
- Conditions
- Functional Abdominal Pain Syndrome, Functional Gastrointestinal Disorders, Irritable Bowel Syndrome
- Trial name
- NCT05486585
- Testing
- Internet delivered cognitive behavioural therapy for functional gastrointestinal disorders
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Aarhus University Hospital
Irritable Bowel Syndrome (IBS), Constipation - Functional
Effect of a Low FODMAP Diet in IBS and Functional Constipation with Bloating: a Randomized Double-Blind Trial
This clinical study aims to evaluate the effects of a low FODMAP diet compared to a high FODMAP diet in patients with Irritable Bowel Syndrome (IBS) and Functional Constipation (FC) with predominant bloating.
- Conditions
- Irritable Bowel Syndrome (IBS), Constipation - Functional, Bloating
- Trial name
- NCT06871748
- Testing
- Low FODMAP Diet, High FODMAP Diet
- Volunteers
- 34 people
- Sponsor
- Mahidol University
Irritable Bowel Syndrome, Healthy Subjects
Application of Diaphragmatic Breathing in Patients With Disorders of Gut-brain Interaction
Patients with disorders of gut-brain interaction (DGBI) often present gastrointestinal symptoms that do not show noticeable irregularities in standard examinations.
- Conditions
- Irritable Bowel Syndrome, Healthy Subjects, Functional Gastrointestinal Disorders, Laryngopharyngeal Reflux
- Trial name
- NCT06205446
- Testing
- Healthy subjects : abdominal breathing, Laryngopharyngeal reflux disease subjects : abdominal breathing, Dyspepsia subjects : abdominal breathing
- Where
- Taiwan
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Buddhist Tzu Chi General Hospital
Functional Constipation, Irritable Bowel Syndrome
NutriPlant - Opportunities for Increasing Consumption of Local Fruits and Vegetables
The effects of different foods to normal bowel function in adult population will be investigated. A randomised controlled intervention trial will be conducted on about 120 (30 per group) adult (18-70 years) subjects with…
- Trial name
- NutriPlant (NCT06785831)
- Testing
- Psyllium, Sauerkraut, Fresh apples
- Where
- Slovenia
- Volunteers
- 120 people
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Functional Gastrointestinal Disorders, Irritable Bowel Syndrome
Hypnotherapy Through Self-exercises in Children With Functional Abdominal Pain in Primary Care
The goal of this randomised controlled trial is to study the (cost-)effectiveness of home-based hypnotherapy by self-exercises in children with functional abdominal pain (FAP) or irritable bowel syndrome (IBS) in primary care.
- Conditions
- Functional Gastrointestinal Disorders, Irritable Bowel Syndrome, Functional Abdominal Pain Syndrome
- Trial name
- ZelfHy (NCT05636358)
- Testing
- Home-based hypnotherapy
- Where
- Netherlands
- Volunteers
- 152 people
- Sponsor
- University Medical Center Groningen