Clinical trials: Bowel; Functional Syndrome
Constipation-predominant Irritable Bowel Syndrome
Laser Acupuncture on Irritable Bowel Syndrome in Females
The aim of the study to investigate effect of laser acupuncture on constipation predominant irritable bowel syndrome in female patients
- Trial name
- NCT05757037
- Testing
- laser acupuncture
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Irritable Bowel Syndrome Constipation Predominant
Effects of ROSE-010 on GI Transit in Constipation Predominant Irritable Bowel Syndrome (C-IBS) Patients
This trial will study the effects of an investigational (not FDA approved) medication, ROSE-010, on the movement of food through the stomach, small intestine and colon in females with constipation predominant irritable bowel…
- Trial name
- NCT01056107
- Testing
- ROSE-010
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Mayo Clinic
Irritable Bowel Syndrome, Digestive System Diseases
Efficacy of a Multi-strain Probiotic in the Treatment of Irritable Bowel Syndrome (IBS)
The Canadian College of Naturopathic Medicine is conducting a research study on Irritable Bowel Syndrome (IBS), a common condition in North America.
- Conditions
- Irritable Bowel Syndrome, Digestive System Diseases, Colonic Diseases, Functional, Colitis, Mucous
- Trial name
- NCT01176227
- Testing
- Kyodophilus multi-strain probiotic capsules
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- The Canadian College of Naturopathic Medicine
Irritable Bowel Syndrome
Effects of Standardized Boswellia Carterii Extract on Irritable Bowel Syndrome Patients
Irritable bowel syndrome (IBS) is a common condition that affects the stomach and intestines. It can cause abdominal pain, bloating, diarrhea, constipation, and changes in bowel habits, which may reduce a person's quality of…
- Trial name
- BC-IBS (NCT07576634)
- Testing
- Boswellia carterii Extract, Educationntal program for IBS patie
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Irritable Bowel Syndrome
Effect of Lactobacillus Casei DG (Enterolactis Plus®) in Patient With Irritable Bowel Syndrome: a Pilot Study
The aim of the study is to collect data for the assessment of the Lactobacillus casei DG (Enterolactis plus®) effect on overall abdominal pain/discomfort, symptoms and gut microbiota composition in patients with Irritable Bowel…
- Trial name
- NCT02371499
- Testing
- Lactobacillus casei DG
- Where
- 5 sites in Italy
- Volunteers
- 44 people
- Sponsor
- SOFAR S.p.A.
Bowel; Functional Syndrome, Rectal Cancer
Long Term Bowel Function Following Rectal Cancer Surgery
In this longitudinal study, 171 patients were evaluated and compared based on the radiation therapy they received. Bowel function was assessed longitudinally with Memorial Sloan Kettering Cancer Center and Wexner scores every 6…
- Trial name
- NCT05339763
- Testing
- chemoradiotherapy
- Where
- Egypt
- Volunteers
- 171 people
- Sponsor
- Mansoura University
Inflammatory Bowel Diseases, Irritable Bowel Syndrome
ALPCO Calprotectin ELISA - Measurement of Calprotectin Levels in Human Stool
The ALPCO Calprotectin ELISA is an in vitro diagnostic test intended to quantitatively measure concentrations of fecal calprotectin in human stool samples. Calprotectin is a protein biomarker of mucosal inflammation.
- Trial name
- NCT03082287
- Testing
- Fecal Calprotectin Level
- Where
- United States
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- American Laboratory Products Company
Fibromyalgia, Irritable Bowel Syndrome
Welfare Benefits in Functional Somatic Disorders
The objective of this observational study is to estimate the number of weeks of welfare benefits, i.e. sickness benefit, unemployment benefit and social assistance, for individuals with functional somatic disorders and compare…
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Chronic Fatigue Syndrome, Bodily Distress Syndrome
- Trial name
- NCT05611606
- Volunteers
- 9,656 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Abdominal Pain, Gallstone; Colic
RELIEF-pathway in Patients With Upper Abdominal Pain
Upper abdominal pain (UAP) is a common symptom and frequently the reason to visit the hospital. The prevalence of epigastric pain in the Dutch population is estimated to be as high as 37%.
- Conditions
- Abdominal Pain, Gallstone; Colic, Dyspepsia, Irritable Bowel Syndrome
- Trial name
- RELIEF (NCT06002516)
- Testing
- RELIEF-pathway
- Where
- Netherlands
- Volunteers
- 471 people
- Sponsor
- Radboud University Medical Center
Irritable Bowel Syndrome
SH-DS01 on Fecal Metagenomic Stability
This is a randomized, double blind, Phase 1 study. There will be a 12-week comparison of the safety of DS-01 versus placebo with a secondary outcome measure of the efficacy in a cohort of 100 men or women with IBS with…
- Trial name
- NCT04598295
- Testing
- DS-01
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Beth Israel Deaconess Medical Center
Irritable Bowel Syndrome, Lactose Intolerant
Predictive Value of Hydrogen/Methane Lactose Breath Testing on the Therapeutic Effect of Lactose-free Diet in Moderate to Severe ROME IV IBS.
Lactose intolerance (LI) results from lactose malabsorption (LM) secondary to insufficient hydrolysis of the disaccharide lactose into galactose and glucose (Misselwitz 2019).
- Trial name
- NCT04974593
- Testing
- low fat diet
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- Universitair Ziekenhuis Brussel
Intestinal Diseases, Irritable Bowel Syndrome
Biomarkers for Intestinal Permeability in Patients With Constipation
Our overall objective with this study is firstly to provide a comprehensive assessment of intestinal permeability, mucosal barrier function using existing biomarkers and secondly to explore novel biomarkers for measuring…
- Conditions
- Intestinal Diseases, Irritable Bowel Syndrome, Constipation
- Trial name
- NCT02246647
- Testing
- Permeability measurement, Esophagogastroduodenoscopy, Flexible sigmoidoscopy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
IBS - Irritable Bowel Syndrome
Online, Gut-directed Hypnotherapy for Patients With Irritable Bowel Syndrome (IBS)
Adult IBS patients with symptoms refractory to standard medical treatment will receive online nurse-administered, gut-directed hypnotherapy in groups. The primary outcome measure was change in gastro-intestinal symptom severity.
- Trial name
- NCT06297785
- Testing
- Gut-directed hypnotherapy
- Where
- 2 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- Sahlgrenska University Hospital
IBS
Effects of Mexiletine on Colonic Transit in a Patient With Irritable Bowel Syndrome - Constipation (IBS-C)
To understand if Mexiletine will restores normal colonic motility in a patient with irritable bowel syndrome - constipation (IBS-C) and a genetic mutation in SCN5A.
- Trial name
- NCT01717404
- Testing
- Mexiletine
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Rheumatoid Arthritis, Diabetic Neuropathy
Basket Study (CT-100-002) to Evaluate the Effects of a DiNaMo™ Component Training
CT-100 is a platform that provides interactive, software based therapeutic components that may be used as part of a multimodal treatment in supplementary or standalone prescription or nonprescription software-based digital…
- Conditions
- Rheumatoid Arthritis, Diabetic Neuropathy, Fibromyalgia, Irritable Bowel Syndrome
- Trial name
- NCT05573685
- Testing
- DiNaMo Study App
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Click Therapeutics, Inc.
Irritable Bowel Syndrome (IBS)
Genetic Determinism of Epithelial Barrier Defects in Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) profoundly affects the quality of life. Mucosal micro-inflammation, epithelial permeability disorder and proteases activity increase have been demonstrated in the patients' gastrointestinal tract.
- Trial name
- PROTIBS (NCT02841878)
- Testing
- Analysis on colorectal biopsy
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire de Nice
Irritable Bowel Syndrome
Effects of Low FODMAP Diet on Leaky Gut
The pathophysiology of Irritable bowel syndrome (IBS) is multifactorial involving complex interplay of altered intestinal permeability, mucosal immune activation, visceral hypersensitivity and gut dysbiosis.
- Trial name
- NCT04526808
- Testing
- FODMAP diet
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Beth Israel Deaconess Medical Center
Irritable Bowel Syndrome
Defining Objective Markers of Compliance for Dietary Therapies in IBS
This research will investigate if a specific marker in your stool or urine can be used to track changes in your carbohydrate intake including fructo-oligosaccharide and mannitol intake
- Trial name
- NCT07494968
- Testing
- Diet A - elimination diet, Diet B - healthy eating diet
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- University of Michigan
Irritable Bowel Syndrome (IBS)
Evaluate the Effect of Synbiotics in Irritable Bowel Syndrome
Irritable Bowel Syndrome (IBS) is a brain-gut-disorder characterized by a chronic relapsing-remitting nature of symptoms, including abdominal pain and altered bowel habits.
- Trial name
- IBSXtra02 (NCT06647043)
- Testing
- SMT04 Pro
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- Universiti Sains Malaysia
Diarrhoea Predominant Irritable Bowel Syndrome
Quality of Life in Diarrhea-predominant Irritable Bowel Syndrome Taking GABA
The study aims to evaluate the impact on quality of life and abdominal discomfort of GABA and Melissa food supplement administration in patients with diarrhea-predominant irritable bowel syndrome.
- Trial name
- NCT06755489
- Testing
- GABA
- Where
- 2 sites in Italy
- Volunteers
- 20 people
- Sponsor
- University of Pisa