Clinical trials: Bowel Cleansing for Colonoscopy
Diabetes Mellitus, Colonic Diseases
Improvement of Tolerance of Bowel Cleansing Before Colonoscopy in Diabetic Patients
This trial will compare the tolerance to 2 different methods for colon cleansing before colonoscopy in diabetic patients.
- Trial name
- iDIMEPREP (NCT02297399)
- Testing
- PEG-ascorbate 2L, PEG 4L
- Where
- 2 sites in Spain
- Volunteers
- 158 people
- Sponsor
- Parc de Salut Mar
Bowel Preparation
Effect and Safety of Polyethylene Glycol Combined With Linaclotide on Colon Cleansing for Patients With Chronic Constipation
Constipation is a common reason of poor bowel preparation, which negatively influences the quality of colonoscopy. Clinically to explore more effective and tolerant bowel clearance programs is necessary for patients with chronic…
- Trial name
- NCT05137145
- Testing
- Linaclotide, Compound Polyethylene Glycol Electrolyte Powder
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Colorectal Cancer, Colonic Adenoma
Bowel Cleansing Performance of the Pure-Vu System in Patients With a History of Poor Bowel Preparation
The diagnostic accuracy and safety of colonoscopy highly depends on the quality of the pre-procedural bowel preparation. A past history of poor bowel preparation is the most important risk factor of inadequate bowel cleansing at…
- Conditions
- Colorectal Cancer, Colonic Adenoma, Bowel Preparation
- Trial name
- NCT04700410
- Testing
- Pure-Vu System
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 44 people
- Sponsor
- Radboud University Medical Center
Bowel Preparation for Colonoscopy
Evaluation of the Quality of Bowel Cleansing in a Real Clinical Practice Setting
Publications of the use of bowel cleansers in usual clinical practice are lacking. Patient adherence to investigational products increases in the context of clinical trials.
- Trial name
- CALICOL (NCT02839824)
- Testing
- Bowel preparation
- Where
- Spain
- Volunteers
- 412 people
- Sponsor
- Casen Recordati S.L.
Bowel Cleansing Prior to Clinical Procedures
A Study to Investigate Bowel Cleansing With PLENVU® Compared to Sodium Picosulfate in Participants Aged 1 to < 18 Years of Age in Preparation for Colonoscopy
The purpose of the study is to assess the efficacy, safety and tolerability of PLENVU® by measuring its bowel cleansing success rate compared to sodium picosulfate in paediatric participants aged less than 18 years who are…
- Trial name
- CLARITY (NCT07218523)
- Testing
- PLENVU®, Sodium picosulfate
- Where
- 46 sites in Belgium, Croatia and 8 more
- Volunteers
- 212 people
- Sponsor
- Norgine
Colonic Polyps
Evaluation of Computer-assisted, Non-cathartic CT Colonography
The purpose of this study is to evaluate the performance of a non-cathartic, computer-assisted form of CT Colonography (Virtual Colonoscopy) for detection of pre-cancerous colon polyps in a group of asymptomatic screening…
- Trial name
- ncCTC (NCT01200303)
- Testing
- non-cathartic CTC
- Where
- 3 sites in United States
- Volunteers
- 605 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Colonoscopy Preparation
Macrogole Versus Sodium Picosulfate in Bowel Cleansing for Colonoscopy in Pediatric Inflammatory Bowel Disease
Children hospitalized at the Department of Pediatric Gastroenterology and Nutrition at the Medical University of Warsaw with suspected or confirmed inflammatory bowel disease (IBD) will be invited to participate in the study.
- Trial name
- NCT07786363
- Testing
- polyethylene glycol (PEG 4000) (Forlax ®), Citrafleet®
- Where
- Poland
- Volunteers
- 125 people
- Sponsor
- Medical University of Warsaw
Need for Bowel Preparation
Efficacy and Safety of Prepopik® in Children for Overall Colon Cleansing in Preparation for Colonoscopy
To study the efficacy and safety of Prepopik® in children aged 9 to 16 years for overall colon cleansing in preparation of colonoscopy
- Trial name
- Prepopik PREA (NCT01928862)
- Testing
- Prepopik® ½ Sachet x 2 (9-12 years), Prepopik® 1 Sachet x 2 (9-12 years), Oral polyethylene glycol (PEG) based preparation (9-12 years)
- Where
- 9 sites in United States
- Volunteers
- 78 people
- Sponsor
- Ferring Pharmaceuticals
Routine Colonoscopy
Evaluation of the Main Determinants of Patient Acceptability of the Bowel Cleansing Procedure, and of Success of Bowel Cleansing and Caecal Intubation
Several factors are important in achieving a successful colonoscopy, including patient acceptability of the bowel cleansing procedure and the overall quality of cleansing.
- Trial name
- NCT01626196
- Testing
- No intervention
- Where
- Italy
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Norgine
Colonoscopy
Bowel Cleansing for Colonoscopy: Comparison Between a Same Day Low-Volume Preparation and a Conventional 4L Split One
The present study is intended to evaluate the effectiveness, tolerability, compliance, and feasibility of the low volume bowel preparation, bisacodyl tablets followed by 2L Polyethylene glycol (PEG) with citrate and simethicone…
- Trial name
- NCT01685853
- Testing
- Bisacodyl plus PEG-CS, PEG 4 litres split
- Where
- Italy
- Volunteers
- 164 people
- Sponsor
- European Institute of Oncology
Colon Cleansing
Efficacy and Safety Study of Sodium Phosphate Tablets vs PEG for Bowel Cleansing
The purpose of this study is to evaluate the efficacy and safety of sodium phosphate tablets compared to split dose of 4 liters of PEG used in adults for bowel cleansing prior to colonoscopy.
- Trial name
- NCT01840553
- Testing
- oral sodium phosphate tablets, polyethylene glycol
- Where
- 19 sites in France, Germany and 1 more
- Volunteers
- 461 people
- Sponsor
- Laboratoires Mayoly Spindler
Colon Cleansing
PMC Split Preparation for Colon Cleansing
This is an endoscopist-blinded, prospective, multicenter study involving adult outpatients aiming at evaluating whether sodium picosulphate/magnesium citrate split dosing is associated to higher efficacy and acceptability in…
- Trial name
- MAGIC-P (NCT01909219)
- Testing
- Sodium picosulphate/magnesium Citrate
- Where
- 2 sites in Italy
- Volunteers
- 862 people, healthy volunteers welcome
- Sponsor
- Luigi Sacco University Hospital
Colon Cancer
Efficacy of Morning-only Bowel Preparation for Afternoon Colonoscopy.
The study aims to study the adequacy of bowel preparation (colon cleansing) for afternoon colonoscopies. The conventional regimen of giving bowel prep on the evening prior to the day of the colonoscopy will be compared with that…
- Trial name
- CCF (NCT00687830)
- Testing
- Polyethylene Glycol afternoon, Polyethylene Glycol morning
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Cleveland Clinic Florida
Elective Colonoscopy
Clinical Trial on Bowel Preparation Comparing Mannitol 100g to Plenvu Both in a Same Day Regimen (CLEARWAY)
This is a study to test the non-inferiority of bowel cleansing with 100 g Mannitol against standard Plenvu® same-day dosing regimen. The 50% of the subjects will receive Mannitol, while the remaining part will receive Plenvu®.
- Trial name
- CLEARWAY (NCT07465705)
- Testing
- 100g of Mannitol, 1L PEG-Asc
- Where
- 18 sites in Belgium, Italy and 3 more
- Volunteers
- 412 people
- Sponsor
- NTC srl
Colorectal Cancer
Factors Influencing Quality of Bowel Cleansing for Colonoscopy in Patients With Colorectal Cancer Surgery; Prospective Observational Study
The aim of this study is to clarify the factors influencing quality of bowel cleansing for colonoscopy in patients with colorectal cancer surgery and confirm the adequate bowel cleaning method for patients with colorectal cancer…
- Trial name
- NCT02139475
- Testing
- Colonoscopy
- Where
- South Korea
- Volunteers
- 273 people
- Sponsor
- Yonsei University
Bowel Preparation Solution
PEG-Asc Vs. SPMC for Bowel Preparation in Capsule-based Procedures
This clinical research study is designed to find out which of two different types of bowel preparation works best for people undergoing capsule-based endoscopy procedures.
- Trial name
- NCT07206329
- Testing
- Polyethylene Glycol plus Ascorbic Acid (PEG-Asc), Sodium Picosulfate with Magnesium Citrate (SPMC)
- Where
- Portugal
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Unidade Local de Saúde do Alto Ave, EPE
Bowel Cleansing, Colonoscopy
Unrestricted Diet for Screening Colonoscopy
Colonoscopy is the technique of choice for the evaluation of the mucosa of the colon. To be able to do the procedure in optimal conditions, it needs to be clean.
- Conditions
- Bowel Cleansing, Colonoscopy, Bowel Cancer
- Trial name
- CriLiP (NCT05032794)
- Testing
- Unrestricted diet before colonoscopy, 1-day low residue diet, Bisacodyl 5 MG
- Where
- 5 sites in Spain
- Volunteers
- 553 people
- Sponsor
- Parc Taulí Hospital Universitari
Bowel Preparation for Colonoscopy
Efficacy, Safety and Tolerability of Magnesium Sulfate With Low-volume Polyethylene Glycol for Colonoscopy Cleansing
Magnesium salts such as magnesium citrate are often combined with polyethylene glycol to make the intestinal preparation before colonoscopy, which has shown high cleaning efficacy.
- Trial name
- NCT06728839
- Testing
- 1L PEG + 50g magnesium sulfate, 3L PEG, 4L PEG
- Volunteers
- 1,329 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colorectal Cancer Screening, Bowel Cleansing for Colonoscopy
Cleansing Options in Out-Patient Setting to Improve Tolerance (COOP SIT) Trial
The purpose of this research is to compare patient preferences for two bowel preparation options: low-volume tablets (Suflave/Sutab) versus the standard colon preparation using Golytely (polyethylene glycol).
- Trial name
- COOP SIT (NCT07215000)
- Testing
- Golytely, Sulfave, Sutab
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Morehouse School of Medicine
Bowel Preparation Scale, the Amount of Air Bubble
Premedication Dyclonine Improves Visibility During Bowel Cleansing for Colonoscopy
In this randomized controlled study, consecutive outpatients scheduled for elective colonoscopy were randomized into two groups. Group A patients (n = 300) used only 3L PEG before colonoscopy.
- Conditions
- Bowel Preparation Scale, the Amount of Air Bubble, Adenoma Detection Rate
- Trial name
- NCT03352700
- Testing
- 3L PEG, 3L PEG+Dyclonine Hydrochloride Mucilage
- Where
- China
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital