Clinical trials: Bowel Functions
Pelvic Organ Prolapse, Rectocele
Multicenter Ventral Mesh Rectopexy Registry Collaborative
The goal of this multicenter observational study is to collect data prospectively of patients with pelvic organ prolapse undergoing ventral mesh rectopexy (as well as rectoceles, entero-/sigmoidoceles/ intussusception/ rectal…
- Conditions
- Pelvic Organ Prolapse, Rectocele, Enterocele, Rectal Prolapse
- Trial name
- M2R2 (NCT05918367)
- Where
- 5 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- University Hospital, Antwerp
Postpartum Pelvic Floor Function and Symptoms
Postpartum pElvic Assisted Recovery With Leva
The goal of this prospective cohort study is to evaluate the feasibility of postpartum pelvic floor muscle training using an FDA-cleared digital therapeutic motion-based device.
- Trial name
- PEARL (NCT06609317)
- Testing
- Digital therapeutic motion-based device
- Where
- 2 sites in United States
- Volunteers
- 25 people
- Sponsor
- University of South Florida
Irritable Bowel Syndrome
Study of a Management Strategy of Functional Bowel Disordes Related to Irritable Bowel Syndrome (IBS) With a Mixture of 8 Microbiotic Strains
The aim of this study is to determine the impact of a 10-day treatment with Lactichoc® on irritable bowel syndrome.
- Trial name
- NCT05213910
- Testing
- Lactichoc, Stool sampling
- Where
- France
- Volunteers
- 189 people
- Sponsor
- PiLeJe
Irritable Bowel Syndrome, Fibromyalgia
Psychological Risk Factors for Functional Somatic Disorders
The objective of this study is to explore the role of neuroticism, perceived stress, and adverse life events, respectively, in the development and perpetuation of functional somatic disorders.
- Conditions
- Irritable Bowel Syndrome, Fibromyalgia, Chronic Fatigue Syndrome, Somatoform Disorders
- Trial name
- NCT05631860
- Volunteers
- 7,493 people
- Sponsor
- University of Aarhus
Crohn Disease, Ulcerative Colitis
Safety and Efficacy of Fecal Microbiota Transplantation
The gut microbiota is critical to health and functions with a level of complexity comparable to that of an organ system. Dysbiosis, or alterations of this gut microbiota ecology, have been implicated in a number of disease…
- Conditions
- Crohn Disease, Ulcerative Colitis, Celiac Disease, Irritable Bowel Syndrome
- Trial name
- NCT04014413
- Testing
- Fecal Microbiota Transplantation
- Where
- Hong Kong
- Volunteers
- 450 people
- Sponsor
- Chinese University of Hong Kong
Irritable Bowel Syndrome
A Multi-center Human Study to Evaluate the Efficacy and Safety of ®GI Flora in Subjects With Irritable Bowel Syndrome
A Multi-center, Randomized, Double-blinded, Placebo-controlled Human Study to Evaluate the Efficacy and Safety of probiotic mixture(®GI Flora) in Subjects with Irritable Bowel Syndrome.
- Trial name
- NCT02419027
- Testing
- GI Flora
- Volunteers
- 116 people
- Sponsor
- Seoul National University Hospital
Pain
Oxycodone/Naloxone (OXN) Combination in Moderate to Severe Non-malignant Pain
The main objective of the study is to observe the OXN treatment of patients with moderate to severe non-malignant pain in daily clinical practise with respect to pain relief and bowel function.
- Trial name
- NCT01167127
- Testing
- Oxycodone hydrochloride and naloxone hydrochloride combination, prolonged release
- Where
- Netherlands
- Volunteers
- 113 people
- Sponsor
- Mundipharma Pharmaceuticals B.V.
Irritable Bowel Syndrome, Anxiety
Standardized Yoga & Meditation Program for Stress Reduction for Adolescents With Irritable Bowel Syndrome
Irritable Bowel Syndrome (IBS) is the most common cause of recurrent abdominal pain in children. IBS is a functional gastrointestinal disorder that is linked to motor and sensory physiology, as well as the central nervous system…
- Conditions
- Irritable Bowel Syndrome, Anxiety, Quality of Life
- Trial name
- NCT05719246
- Testing
- Yoga
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- The Cooper Health System
Irritable Bowel Syndrome
Nursing Management of Irritable Bowel Syndrome (IBS) 2008
The aim of this study is test the efficacy of a comprehensive self-management therapy to decrease abdominal pain/discomfort and improve quality of life in patients with irritable bowel syndrome (IBS) compared to IBS patients…
- Trial name
- NCT00907790
- Testing
- Usual Care (Control Group), Comprehensive Self-Management (CSM)
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Washington
Irritable Bowel Syndrome
Maastricht IBS Cohort
To set up a cohort of at least 400 IBS patients in order to identify different patient subgroups according to phenotypical and genotypical patterns and To set up a biobank for future translational studies on the pathophysiology…
- Trial name
- NCT00775060
- Where
- Netherlands
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Functional Constipation in Children
Effect of Probiotic on Gut Microbiota in Young Children With Functional Constipation
This study was a 28-day, open-label, randomized controlled trial involving infants and toddlers diagnosed with functional constipation. Participants were randomized to receive either Bifidobacterium longum subsp.
- Trial name
- NCT07360535
- Testing
- Probiotic, Lactulose Oral Liquid Product, probiotic + lactulose
- Where
- 2 sites in China, Malaysia
- Volunteers
- 84 people
- Sponsor
- Min-Tze LIONG
Pediatric Inflammatory Bowel Diseases, Pediatric Crohns Disease
Exercise Training in Youth With Inflammatory Bowel Disease
Children and adolescents with inflammatory bowel disease (IBD) suffer from many extra-intestinal side effects, including impaired muscle strength, low aerobic fitness, low bone density, and chronic inflammation.
- Conditions
- Pediatric Inflammatory Bowel Diseases, Pediatric Crohns Disease, Pediatric Ulcerative Colitis
- Trial name
- NCT05591976
- Testing
- Exercise training program
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- McMaster University
Overweight and Obesity in Adults Receiving GLP-1RA Treatment
Yeast Protein Supplementation and Muscle Preservation During GLP-1RA-Induced Weight Loss
The goal of this clinical trial is to evaluate whether yeast protein supplementation can help preserve lean body mass and muscle function in adults with overweight or obesity receiving GLP-1 receptor agonist-related treatment for…
- Trial name
- NCT07817823
- Testing
- Yeast Protein, Whey Protein, Yeast Protein/Whey Protein Blend (1:1)
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Huazhong University of Science and Technology
Irritable Bowel Syndrome, Erectile Dysfunction
Elliptical Physical Activity and Sexual Dysfunction in Males With Irritable Bowel Syndrome
psychological disturbances resulting from irritable bowel syndrome causes sexual dysfunction in men such as weak erection of penis.
- Trial name
- NCT06783894
- Testing
- exercise (elliptical training)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Irritable Bowel Syndrome
Mindfulness-Based Stress Reduction for Bowel Symptoms: Collection of Pilot Survey Data
Irritable bowel syndrome (IBS) is a very common, chronic disorder that significantly affects quality of life, and results in enormous expenditures each year in the United States.
- Trial name
- NCT00880256
- Testing
- mindfulness-based stress reduction
- Where
- United States
- Volunteers
- 93 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Irritable Bowel Syndrome
Dietary Triggers of Gastrointestinal Symptoms in IBS Patients
This crossover randomized controlled trial will evaluate the effects of purified gluten and whole wheat (gluten combined with amylase-trypsin inhibitors (ATIs)) on inducing intestinal and extra-intestinal symptoms in irritable…
- Trial name
- NCT03664531
- Testing
- Purified gluten, Non-purified gluten (containing ATIs)
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- McMaster University
Irritable Bowel Syndrome-IBS
Effect of Different Dietary Therapies on Intestinal Barrier Integrity in Patients With Irritable Bowel Syndrome
This study aims to evaluate the effects of different dietary treatments on intestinal integrity in female subjects aged 19-50 years previously diagnosed with constipation-predominant irritable bowel syndrome (IBS).
- Trial name
- NCT06421922
- Testing
- Group 1 received a regular constipation diet, Group 2 received a constipation diet rich in soluble fiber, Group 3 received a constipation diet supplemented with probiotic yogurt.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gulhane Training and Research Hospital
IBS, Diarrhea Predominant
Transcutaneous Electrical Acustimulation for IBS-D: A Multicenter Study
Irritable bowel syndrome (IBS) is a functional gastrointestinal disorder characterized by recurrent abdominal pain and altered bowel habits.
- Trial name
- NCT07425145
- Testing
- Portable stimulator
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First People's Hospital of Foshan
Rectal Prolapse, Surgery
The Nordic Rectal Prolapse Study
The goal of this observational study is to gather data about surgical procedures for rectal prolapse in adult human subjects. The main question it aims to answer is: Which procedure is best for treating external rectal prolapse?…
- Conditions
- Rectal Prolapse, Surgery, Recurrence, Quality of Life
- Trial name
- NORDIC (NCT05569980)
- Where
- Denmark
- Volunteers
- 430 people
- Sponsor
- Aarhus University Hospital
Intestinal Disease
Neuromuscular Blockade Comparison for GI-2 Recovery After Bowel Resection
The purpose of this research study is to see the outcome of Sugammadex versus Neostigmine with Glycopyrrolate in colorectal surgery as it relates to its effects on post-surgical time (in hours) to first bowel movement and…
- Trial name
- NCT06112353
- Testing
- Neostigmine Injectable Solution, Sugammadex injection
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- University of California, Irvine
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