Clinical trials: Bowel Functions
Rectal Cancer, Rectum Neoplasm
Effect of Pelvic Rehabilitation After Low Anterior Resection for Cancer Rectum. - A Randomised Controlled Trial
Study Purpose: This study aims to understand how pelvic floor rehabilitation (PFR) after low anterior resection (LAR) surgery for rectal cancer affects bowel control and quality of life compared to usual care.
- Conditions
- Rectal Cancer, Rectum Neoplasm, Rectal Neoplasms, Rectal Adenocarcinoma
- Trial name
- PERECARE (NCT06524362)
- Testing
- Pelvic Floor Physiotherapy (PFR), Conventional group
- Where
- India
- Volunteers
- 77 people
- Sponsor
- GEM Hospital & Research Center
Vaginal Surgery
Effect of Pain Vigilance on Pain, Bladder-Bowel Function and Sexual Life
The aim of this study to investigate the effect of preoperative pain hypervigilance on postoperative pain, bladder-bowel symptoms and sexual life after vaginal surgery and to compare these parameters before and after surgery.
- Trial name
- NCT07065188
- Where
- Turkey (Türkiye)
- Volunteers
- 77 people
- Sponsor
- Ordu University
Irritable Bowel Syndrome
Evaluating the Efficacy of the Mediterranean Diet to the Low- Fermentable, Oligosaccharides, Disaccharides, Monosaccharides, and Polyols (FODMAP) Diet in Treating Irritable Bowel Syndrome(IBS)
This study is being completed to determine if the Mediterranean (MD) and low FODMAP (fermentable, oligosaccharides, disaccharides, monosaccharides, and polyols) diets are comparable in the effectiveness to treat Irritable Bowel…
- Trial name
- NCT05807919
- Testing
- Diet low in all FODMAP groups, Diet - Mediterranean
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Michigan
Constipation - Functional
Chronic Ingestion of Fructooligosaccharide and Psyllium on Intestinal Transit in Women With Functional Constipation: A Randomized Crossover Trial
The goal of this clinical trial is to evaluate the effect of dietary fibers in the treatment of functional constipation in women. It will also assess the potential side effects associated with fiber consumption.
- Trial name
- NCT07202481
- Testing
- Psyllium powder, Fructooligosaccharide
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Federal University of Minas Gerais
Laparoscopic Cholecystectomy, Abdominal Distention
Effects of Warm Water on GI System in Laparoscopic Cholecystectomy Patients
Objective: The study was carried out to determine the effect of drinking warm water on GIS functions in patients who underwent laparoscopic cholecystectomy surgery.
- Trial name
- LCSS (NCT06154928)
- Testing
- Drinking Warm Water Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- İslam Elagöz
Surgery, Laparoscopic, Sexual Dysfunction, Physiological
Bowel, Urinary and Sexual Function After Laparoscopic Colorectal Surgery
Research Populations: Male patients scheduled for laparoscopic colorectal surgery Study Method: Questionnaire and function tests Hypothesis: A laparoscopic nerve-sparing operation is not inferior to reported open surgery in…
- Conditions
- Surgery, Laparoscopic, Sexual Dysfunction, Physiological, Colorectal Surgery
- Trial name
- NCT00451165
- Testing
- laparoscopic colorectal surgery
- Where
- Japan
- Volunteers
- 36 people
- Sponsor
- Kyoto University
Patient Education, IBS - Irritable Bowel Syndrome
Patient Education for Patients With Irritable Bowel Syndrome (IBS)
In this randomized controlled study in patients with irritable bowel syndrome (IBS) the investigators plan to compare the effects of a structured patient group education (IBS School) with structured education provided via the…
- Trial name
- IBS (NCT03466281)
- Testing
- Structured patient group education, Education via Internet
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Sahlgrenska University Hospital
Urinary Incontinence, Pelvic Organ Prolapse (POP)
The RECOVER Study - Postpartum Recovery of Pelvic Floor Structures and the Impact of Early Rehabilitation
The goal of this observational study with an embedded pilot clinical trial is to learn how the pelvic floor recovers after vaginal childbirth and whether early individualized pelvic floor muscle training can improve recovery in…
- Conditions
- Urinary Incontinence, Pelvic Organ Prolapse (POP), Bowel Symptoms, Postpartum
- Trial name
- RECOVER (NCT07430865)
- Testing
- Early individualized pelvic floor muscle training (PFMT)
- Where
- 2 sites in Sweden
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Vastra Gotaland Region
Gastrointestinal Disorder, Functional
Effect of Oat Bran on Bowel Function and Appetite
The consumption of oat bran fiber also has a significant bulking effect in humans. However, besides fecal bulk, dietary fiber can promote gut health in other ways.
- Trial name
- OATGUT (NCT03014141)
- Testing
- Oat bran (Oatwell 28), Maltodextrin
- Volunteers
- healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Irritable Bowel Syndrome
Cognitive Behavior Therapy (CBT) Compared to Stress Management for Irritable Bowel Syndrome
The study aims to compare two manualized treatments. They are based on cognitive behavior therapy or stress management. Both treatments are delivered via an internet application and the patients' work with the treatments is…
- Trial name
- NCT01051973
- Testing
- Cognitive behavior therapy, Stress management
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Karolinska Institutet
IBS - Irritable Bowel Syndrome, Diarrhea
Novel Pilot Study to Treat Symptoms of IBS With Diarrhea Using Combination Therapy of a Low-FODMAP Diet and a Neuromodulator
The purpose of this research is to study the added benefit of treating IBS symptoms with a medication called mirtazapine in treating IBS symptoms when paired with a low-FODMAP diet compared to a low-FODMAP diet alone.
- Trial name
- NCT06684470
- Testing
- Mirtazapine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Gastrointestinal Disorder Postoperative
Gum Chewing and Postoperative Intestinal Function After Gynecolgic Operations
The investigators aimed to assess whether postoperative gum chewing improve intestinal functions.
- Trial name
- NCT02455739
- Testing
- chewing gum
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Intestinal Permeability, Gastrointestinal Function
The Effect of a Cranberry Beverage on Intestinal Permeability and Gastrointestinal Function in Generally Healthy Adults
In this double blind, crossover study participants will consume a cranberry beverage and a cranberry-flavored beverage for 2 weeks each. Gut permeability will be assessed weekly using aspirin and food-grade sugar molecules.
- Trial name
- MAC (NCT03957239)
- Testing
- Cranberry Beverage, Control Beverage
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Florida
Spinal Cord Injuries, Constipation
Neostigmine and Glycopyrrolate by Iontophoresis
To determine a lower effective dose of neostigmine to induce bowel evacuation by transcutaneous administration by iontophoresis.
- Conditions
- Spinal Cord Injuries, Constipation, Fecal Incontinence, Neurogenic Bowel
- Trial name
- NCT06351995
- Testing
- Combination of Neostigmine and Glycopyrrolate, I-Box by Dynatronics
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Calcific Aortic Valve Disease, Inflammation
Impact of TAVI on the Gut Microbiota and Its Metabolites
Aortic stenosis is a common heart valve disease in older adults. It occurs when the aortic valve becomes narrowed, making it harder for blood to flow from the heart to the rest of the body.
- Conditions
- Calcific Aortic Valve Disease, Inflammation, Dysbiosis, TAVI
- Trial name
- Swiss-GUT-TAVI (NCT07565077)
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Irritable Bowel Syndrome (IBS)
Effect of HMOs as Nutritional Support for Normal Bowel Movements in IBS Patients
This is an open labeled, one-armed real-world study in IBS-patients. All participants will receive active treatment for 12 weeks.
- Trial name
- GRIPS (NCT03550742)
- Testing
- Fuco-N-Tetraose
- Where
- United States
- Volunteers
- 317 people
- Sponsor
- Glycom, Inc.
Irritable Bowel Syndrome
Resilience in Irritable Bowel Syndrome and Gut-focused Hypnotherapy
Background: Resilience refers to a class of variables highly relevant for wellbeing and coping with stress, trauma, and chronic adversity.
- Trial name
- NCT02737410
- Testing
- Gut-directed Hypnotherapy
- Where
- Austria
- Volunteers
- 74 people
- Sponsor
- Medical University of Vienna
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Irritable Bowel Syndrome
Effects of Lactose-free Dairy Products on Athletes With Irritable Bowel Syndrome
Irritable Bowel Syndrome (IBS) is a gastrointestinal disorder defined by recurrent abdominal pain, bloating, abdominal distention and altered bowel habits. IBS is common among athletes and can impair performance.
- Trial name
- NCT05001997
- Testing
- Lactose free probiotic yogurt
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Central Lancashire
Irritable Bowel Syndrome
Comparing the Effectiveness of 2 Diets for Patients With Irritable Bowel Syndrome
The purpose of the study is to find out if the diets often recommended for patients with Irritable Bowel Syndrome with diarrhea (IBS-D) provide adequate relief.
- Trial name
- NCT01624610
- Testing
- Dietary intervention
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
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