Clinical trials: Bowel Functions
Irritable Bowel Syndrome
Effects of Dietary Fibre in Irritable Bowel Syndrome (IBS)
The aim of the study is to investigate how different dietary fibre combinations affects physiological and microbiological outcomes, in addition to symptoms in those with IBS.
- Trial name
- NCT03803319
- Testing
- Fibre 1 (combined fibres), Fibre 2 (natural fibres)
- Where
- United Kingdom
- Volunteers
- 135 people
- Sponsor
- King's College London
Colorectal Cancer
Enhanced Recovery After Surgery in Patients Undergoing Colorectal Cancer Surgery
This study compared an Enhanced Recovery After Surgery (ERAS) care program with conventional perioperative care in adults undergoing surgery for colorectal cancer. Participants received either ERAS care or usual care.
- Trial name
- NCT07889934
- Testing
- Enhanced Recovery After Surgery (ERAS) Pathway, Conventional Perioperative Care
- Where
- Greece
- Volunteers
- 91 people
- Sponsor
- University of West Attica
Irritable Bowel Syndrome, Stigma
Effect of a Psychological Intervention on Stigma: a Randomized Controlled Study
The purpose of this study was to construct a Stigma intervention program for college students with Irritable Bowel Syndrome (IBS) based on the Acceptance and Commitment Therapy (ACT) theory and to investigate the effectiveness in…
- Conditions
- Irritable Bowel Syndrome, Stigma, Psychological Intervention
- Trial name
- NCT06456710
- Testing
- Conventional IBS Health Education, Based on ACT Theory of Psychological Intervention
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Yangzhou University
Irritable Bowel Syndrome
Effectiveness of a Dietary Supplement in Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) affects around 5% of the general population and remains a daily problem in clinicians' practices, with inconsistent efficacy of treatments despite patients' high expectations.
- Trial name
- ACALMI (NCT07039747)
- Testing
- treatment with DIELEN® Protect
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Rouen
Irritable Bowel Syndrome With Constipation
A Safety and Efficacy Study of a Range of Linaclotide Doses Administered Orally to Children Ages 7-17 Years, With Irritable Bowel Syndrome With Constipation
The purpose of this study is to evaluate the safety and efficacy of linaclotide for the treatment of Irritable Bowel syndrome with Constipation (IBS-C), in children age 7-17 years.
- Trial name
- LIN-MD-63 (NCT02559817)
- Testing
- Linaclotide Dose A, Linaclotide Dose B, Linaclotide Dose C
- Where
- 48 sites in United States, Canada
- Volunteers
- 101 people
- Sponsor
- Forest Laboratories
Injuries, Spinal Cord, Neurogenic Bowel
Evaluation of a Bowel and Bladder Health Management Program for Individuals With Spinal Cord Injury (SCI)
This study will look at the use of a telehealth version of a self management program in individuals with both new onset and chronic traumatic spinal cord injuries. The program is called Health Mechanics.
- Conditions
- Injuries, Spinal Cord, Neurogenic Bowel, Urinary Bladder, Neurogenic
- Trial name
- NCT01920243
- Testing
- Health Mechanics Program
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Michigan
Irritable Bowel Syndrome (IBS)
IBS-Oriented CDED Versus Low FODMAP Diet for Irritable Bowel Syndrome
Background: Irritable Bowel Syndrome (IBS) affects approximately 4.1% of the global population and imposes a significant personal and healthcare burden.
- Trial name
- IBS-CDED (NCT07707635)
- Testing
- Modified Crohn's Disease Exclusion Diet (CDED), Low FODMAP Diet
- Volunteers
- 150 people
- Sponsor
- Ariel University
Hysterectomy, Benign Uterine Diseases, Hysterectomy, Vaginal
Effect of Abdominal Ice Pack After vNOTES Hysterectomy
This randomized, controlled, open-label, parallel-group clinical trial is designed to investigate the efficacy of abdominal ice pack application as an adjunct to standard pain management following vNOTES (Vaginal Natural Orifice…
- Conditions
- Hysterectomy, Benign Uterine Diseases, Hysterectomy, Vaginal, vNOTES, Postoperative Pain Following Hysterectomy
- Trial name
- NCT07626684
- Testing
- Abdominal Ice Pack + ERAS
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people
- Sponsor
- Erzincan Military Hospital
Irritable Bowel Syndrome
A Multi-Center Trial to Determine the Safety and Efficacy of LX1033 in Subjects With Diarrhea-Predominant Irritable Bowel Syndrome
The objective of this study is to evaluate the safety and efficacy of LX1033 over a range of dose levels in subjects with diarrhea-predominant Irritable Bowel Syndrome (IBS).
- Trial name
- NCT01494233
- Testing
- 250 mg LX1033 tablets
- Where
- 81 sites in United States
- Volunteers
- 373 people
- Sponsor
- Lexicon Pharmaceuticals
Irritable Bowel Syndrome, Constipation
Cognitive Behaviour Therapy for Patients With IBS
Irritable bowel syndrome (IBS) affects approximately 10-15% of the adult population. This condition is characterized by abdominal pain, altered bowel habit, abdominal bloating and reduced quality of life.
- Conditions
- Irritable Bowel Syndrome, Constipation, Abdominal Pain, Depression
- Trial name
- EFI (NCT00788658)
- Testing
- Diet modifications, Cognitive behavioral therapy
- Volunteers
- 100 people
- Sponsor
- Rabin Medical Center
Irritable Bowel Syndrome (IBS)
Feasibility of an Online Cognitive Behavioural Therapy Application (Mahana IBS™, Mahana Therapeutics) in the Management of Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a very common condition where patients suffer from recurrent episodes of tummy pain associated with the way the bowel works (either constipation, diarrhoea, or a mix of both).
- Trial name
- MahanaPilot (NCT07008404)
- Testing
- online cognitive behavioral therapy
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Bladder-Bowel Dysfunction, Obesity & Overweight
Target Physiotherapy Versus Exercise Support Intervention for Bladder-bowel Dysfunction in Adolescents With Obesity
Bladder and bowel dysfunction (BBD) is a common condition that includes problems such as urinary urgency, daytime urinary incontinence, bedwetting, constipation, or difficulties emptying the bladder or bowel.
- Trial name
- OBE-BBD (NCT07724158)
- Testing
- Target physiotherapy, Exercise support intervention, Usual obesity care
- Where
- Portugal
- Volunteers
- 237 people
- Sponsor
- University of Lisbon
Colorectal Cancer, Quality Improvement
ERAS (Enhanced Recovery After Surgery) Protocol Implementation in Piedmont Region for Colorectal Cancer Surgery
The study assesses the impact on quality of care of implementing the ERAS (Enhanced Recovery After Surgery) protocol for colorectal cancer surgery in the network of public hospitals in the Regione Piemonte (North-West Italy).
- Conditions
- Colorectal Cancer, Quality Improvement, Perioperative Care, Recovery of Function
- Trial name
- ERAS-Colon (NCT04037787)
- Testing
- ERAS protocol
- Where
- Italy
- Volunteers
- 2,397 people
- Sponsor
- Ospedale Santa Croce-Carle Cuneo
Irritable Bowel Syndrome, Diarrhea
Fecal Microbiota Transplantation for IBS
The purpose of this study is to learn the efficacy and safety of fecal microbiota transplantation (FMT) using stool from a donor with low proteolytic activity and containing the bacteria Alistipes putredinis in patients with…
- Trial name
- NCT05776914
- Testing
- Donor Fecal Microbiota Transplantation, Autologous Fecal Microbiota Transplantation
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Madhusudan (Madhu) Grover, MBBS
Rectum Cancer, Pelvic Cancer
Assessment of DW-MRI Measures : Reproducibility and Repeatability in Pelvic Imaging on MR-Linac With Healthy Volunteers
This study evaluates the reliability of functional MRI measurements in pelvic disease through quantifying repeatability and reproducibility, using healthy volunteers.
- Trial name
- PILLAR (NCT06458725)
- Testing
- Magnetic Resonance Imaging (MRI)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Jules Bordet Institute
Ileus
Neurostimulation for the Treatment of Post-Operative Ileus
The primary goal of this study is to validate the design of the ElectroCore RMS-1100 Resolution Motility System™ and the ability to safely place a stimulation electrode in the epidural space of the spine in a post-operative…
- Trial name
- NCT00854074
- Testing
- ElectroCore RMS-1100 Resolution Motility System™
- Where
- 3 sites in United States
- Sponsor
- ElectroCore INC
Irritable Bowel Syndrome
Assessment of Psilocybin (TRP-8802) in Concert With Psychotherapy in Patients With Irritable Bowel Syndrome (IBS)
Participants with IBS (all subtypes) and with no exclusionary comorbid psychiatric or medical disorders will be enrolled in the study.
- Trial name
- NCT06206265
- Testing
- TRYP-0082, Psychotherapy
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- TRYP Therapeutics
AI Care Device
Artificial Intelligence-based Dietary Care System
Patients with rectal cancer complicated by low anterior resection syndrome who undergo anal-preserving surgery may experience severe distress in daily life due to changes in bowel function, thus requiring significant…
- Trial name
- AI DC-system (NCT07637565)
- Testing
- Artificial Intelligence-based Dietary Care System, Routine Care
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Functional Disorder of Intestine
Bowel Function After Minimally Invasive Urogynecologic Surgery
The purpose of this study is to assess the effect of a standardized postoperative bowel regimen of over-the-counter medications in subjects undergoing minimally invasive urogynecologic surgery.
- Trial name
- NCT01044212
- Testing
- Docusate, Bowel medications
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Short Bowel Syndrome, Malabsorption Syndromes
Safety and Efficacy of Crofelemer in Adult Patients With Short Bowel Syndrome and Intestinal Failure (SBS-IF) Without Colon-in-continuity (CIC)
A 24-week, randomized, placebo-controlled, double-blind study to evaluate the efficacy, safety and tolerability of crofelemer in patients with Short Bowel Syndrome and Intestinal Failure (SBS-IF) without colon-in-continuity (CIC)…
- Conditions
- Short Bowel Syndrome, Malabsorption Syndromes, Short Gut Syndrome, Post-Op Complication
- Trial name
- CRO-SBS-IF (NCT06904872)
- Testing
- Crofelemer Powder for Oral Solution
- Where
- 8 sites in Germany, Italy
- Volunteers
- 18 people
- Sponsor
- Napo Therapeutics, S.p.A.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.