Clinical trials: Bowel Habits
Sanitation
Research on the Impact of Targeted Subsidies Within Open Defecation Free (ODF) Communities
This study evaluates targeted subsidies as a strategy to improve sanitation infrastructure and behaviours in communities that have reached Open Defecation Free (ODF) status after a Community-Led Total Sanitation (CLTS) program.
- Trial name
- NCT03822611
- Testing
- Targeted Subsidy
- Where
- Ghana
- Volunteers
- 5,615 people, healthy volunteers welcome
- Sponsor
- The Aquaya Institute
Mental Health Wellness 1, Happiness
Effects of an 8-day Advanced Meditation, Samyama on Physical, Psychological and Spiritual Wellbeing ,and Associated Neural Mechanisms
The purpose of this study is to investigate the effects of Samyama program on blood levels of selected neurotransmitters before and after the program, and associate with corresponding effects on mind/psyche before and after the…
- Conditions
- Mental Health Wellness 1, Happiness, Depression, Consciousness, Level Altered
- Trial name
- NCT04366544
- Testing
- Part A1: Survey, Part A2: Sample collection, Part B:
- Where
- United States
- Volunteers
- 759 people, healthy volunteers welcome
- Sponsor
- Indiana University
Colorectal Cancer
Determining Energy Needs in Colorectal Cancer
This is an observational study to assess the determinants of energy expenditure in cancer, and how those change throughout the disease trajectory.
- Trial name
- RECODE (NCT03131921)
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Alberta
Bowel Movement Regulation, Occasional Constipation
Effect of Bacillus Subtilis DE111® on Daily Bowel Movements
The purpose of this study is to determine the efficacy of Bacillus subtilis DE111® probiotic for regulation of bowel movements.
- Conditions
- Bowel Movement Regulation, Occasional Constipation, Occasional Diarrhea
- Trial name
- NCT04083521
- Testing
- Bacillus subtilis DE111®
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Deerland Enzymes
Constipation
Effect of Agar Administration on Defecation and Fecal Condition in Chronic Constipated Patients
The administration of agar jelly may increase the number of defecation and the volume of feces, and then may improve fecal condition in chronic constipated patients.
- Trial name
- NCT02012543
- Testing
- Agar jelly
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Showa Inan General Hospital
MRI Defecography, ODS
Role of MRI Defecography in Diagnosis of Obstructed Defecation Syndrome
The aim of the study was to assess the advantages of dynamic magnetic resonance imaging defecography to elucidate the underlying anatomic and pathophysiologic background in obstructed defecation patients to guide physicians in…
- Trial name
- NCT03841006
- Testing
- MRI
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alshimaa Abdalkreem
GI Issues, Bowel Movements
The Effect of Humiome® Post LB on Gut COMFort in healthY Adult Volunteers
The goal of this double-blind, randomized placebo-controlled study is to evaluate the effect of an 8-week supplementation of Humiome ® Post LB (170 mg) on bowel movements in healthy adult volunteers compared to Placebo adjusted…
- Conditions
- GI Issues, Bowel Movements, Gastrointestinal Symptoms
- Trial name
- NCT06937814
- Testing
- Humiome ® Post LB
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Dyssynergia, Constipation
Fecobionics in Biofeedback Therapy in Dyssynergia Patients
Constipation affects 12-19% of Americans. Pelvic floor dyssynergia is considered to play an important role in constipation but the underlying mechanisms are not well understood in individual patients.
- Trial name
- NCT05807321
- Testing
- Fecobionics
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- The California Medical Innovations Institute, Inc.
Postoperative Ileus
Effects of Intravenous Local Anesthetic on Bowel Function After Colectomy
Epidural local anesthetics are the gold standard for shortening duration of bowel dysfunction after bowel surgery. Previous studies suggest that their effect may be in part a result of actions of the local anesthetic outside the…
- Trial name
- NCT00600158
- Testing
- bupivacaine with hydromorphone, lidocaine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Virginia
Postoperative Bowel Function Recovery
Effects of Analgesia Nociception Index (ANI)-Guided Analgesia on Postoperative Bowel Function.
Investigators will examaine the effects of Analgesia Nociception Index (ANI)-guided analgesia on postoperative bowel function recovery in laparoscopic colorectal surgery. This is a prospective randomized-controlled study.
- Trial name
- NCT05122078
- Testing
- ANI, Control
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Gangnam Severance Hospital
Digestive Discomfort, Constipation
Bacillus Coagulans Effect on Gastrointestinal Function in Healthy Adults.
A single centre, double-blind, placebo-controlled study to evaluate the effect of the consumption of Bacillus coagulans at a daily dose of 1 x 10⁹ CFU on bowel habits, intestinal microbiota and gastrointestinal symptoms in…
- Conditions
- Digestive Discomfort, Constipation, Microbiota
- Trial name
- NCT06644001
- Testing
- Bacillus coagulans GBI-30,6086 (BC GBI-30)
- Where
- China
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Kerry Group P.L.C
Acupressure, Post-Op Complication
Effect of Acupressure on Recovery of Bowel Function in Patients Post Cesarean Section
Research objectives To compare the efficacy of acupressure with no acupressure to examine time to first flatus in patient post cesarean section ; Acupressure at ST-36 Zusanli (lateral to anterior crest of tibia, in the tibialis…
- Conditions
- Acupressure, Post-Op Complication, Cesarean Section, Bowel Ileus
- Trial name
- NCT04620850
- Testing
- Acupressure
- Where
- Thailand
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Dyssynergic Defecation, Puborectalis Syndrome
Puborectalis Syndrome as a Phenotype of Dyssynergic Defecation in Chronic Constipation: a Comparative Study of Defecography,High-resolution Anorectal Manometry, and Pelvic Floor Ultrasound
Patients with suspected DD who met the Rome IV criteria were divided into the DD group and other types of constipation groups. The differences between the two groups were analyzed to explore the precise diagnostic scheme for DD.
- Conditions
- Dyssynergic Defecation, Puborectalis Syndrome, Impaired Rectal Evacuation
- Trial name
- NCT07683390
- Testing
- Analysis of inter-group differences
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Third Military Medical University
Sensation of Inadequate Defecation, Rectal Prolapse
Surgical Treatment of Obstructed Defecation Syndrome
Obstructed Defecation is a profoundly disabling condition. Many different surgical procedures has been introduced to treat patients affected by this disease. The most used are STARR and ventral rectopexy.
- Conditions
- Sensation of Inadequate Defecation, Rectal Prolapse, Rectocele
- Trial name
- PRO-REST (NCT01899209)
- Testing
- STARR, Laparoscopic Ventral Rectopexy
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Diverticulitis of Sigmoid
Bowel Function/QoL After Elective Sigmoidectomy vs. Conservative Management for Recurrent Uncomplicated Diverticulitis
The decision to perform a surgical intervention or not after recovery from repeated uncomplicated episodes of acute diverticulitis remains controversial and the literature shows different conflicting approaches based on…
- Trial name
- NCT03994978
- Testing
- elective sigmoidectomy
- Where
- Switzerland
- Volunteers
- 252 people
- Sponsor
- University Hospital, Basel, Switzerland
Healthy With Hard and/or Lumpy Stools
The Inside Study II: Oligosaccharides Versus Placebo and Hard Stools
In the present randomised double blind controlled study, we will study the effects of a oligosaccharides vs a placebo on the change in stool consistency and stool frequency in children with hard or lumpy stools.
- Trial name
- NCT04295213
- Testing
- oligosaccharides
- Where
- Netherlands
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Wageningen University and Research
Rectal Cancer, Rectum Neoplasm
Effect of Pelvic Rehabilitation After Low Anterior Resection for Cancer Rectum. - A Randomised Controlled Trial
Study Purpose: This study aims to understand how pelvic floor rehabilitation (PFR) after low anterior resection (LAR) surgery for rectal cancer affects bowel control and quality of life compared to usual care.
- Conditions
- Rectal Cancer, Rectum Neoplasm, Rectal Neoplasms, Rectal Adenocarcinoma
- Trial name
- PERECARE (NCT06524362)
- Testing
- Pelvic Floor Physiotherapy (PFR), Conventional group
- Where
- India
- Volunteers
- 77 people
- Sponsor
- GEM Hospital & Research Center
Gastroschisis
Evaluation of Glycerin Suppositories to Improve Bowel Function in Gastroschisis
Gastroschisis is a congenital defect of the abdominal wall that leads to evisceration of various amounts of the abdominal organs.
- Trial name
- NCT03355326
- Testing
- Glycerin Suppository
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Indiana University