Clinical trials: Bowel Habits
Obstructed Defaecation Syndrome
Obstructed Defaecation: Proctography Versus Ultrasound in Symptomatic Patients
Obstructed defaecation syndrome is a common problem in which patients experience difficulty to evacuate stools and feel that the bowel is incompletely empty, which causes the need to put fingers in to the rectum or vaginal to…
- Trial name
- OPUS (NCT02239302)
- Where
- United Kingdom
- Volunteers
- 131 people
- Sponsor
- Croydon University Hospital
Irritable Bowel, Irritable Bowel Syndrome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in IBS
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Irritable Bowel, Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea, Irritable Bowel Syndrome Mixed
- Trial name
- NCT04214470
- Testing
- No intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Bowel Habits, Gut Microbiomes
Study on Changes in Gut Microbiota, Inflammatory Factors, and Bowel Habits Following Oral Administration of Recombinant B-subunit/Whole Cell Cholera Vaccine in a Community Population
This randomized, placebo-controlled clinical trial aims to investigate the effects of oral cholera vaccine administration on three aspects of gut health in healthy adult community members aged 18 years and older: (1) the…
- Conditions
- Bowel Habits, Gut Microbiomes, Inflamatory Markers
- Trial name
- NCT07873346
- Testing
- Receive recombinant B-subunit/whole-cell cholera vaccine
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zhejiang Provincial Center for Disease Control and Prevention
Irritable Bowel Syndrome With Diarrhea, Irritable Bowel Syndrome With Mixed Bowel Habits
FODMAP Reintroduction in Irritable Bowel Syndrome
The purpose of this study is to determine the amount and timing of when certain Fermentable Oligo-Di-Monosaccharides and Polyols (FODMAPs), specifically fructose, can be safely reintroduced into the diet of Irritable Bowel…
- Trial name
- NCT03245645
- Testing
- Dietary Intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, Los Angeles
GI Issues, Bowel Movements
The Effect of Humiome® Post LB on Gut COMFort in healthY Adult Volunteers
The goal of this double-blind, randomized placebo-controlled study is to evaluate the effect of an 8-week supplementation of Humiome ® Post LB (170 mg) on bowel movements in healthy adult volunteers compared to Placebo adjusted…
- Conditions
- GI Issues, Bowel Movements, Gastrointestinal Symptoms
- Trial name
- NCT06937814
- Testing
- Humiome ® Post LB
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- dsm-firmenich Switzerland AG
Chronic Constipation
Elobixibat for Chronic Constipation Without Defecation Desire
Patients of chronic constipation without defecation desire will be orally administered elobixibat 10 mg once daily before meals for 4 weeks.
- Trial name
- R-LODD (NCT05165199)
- Testing
- Elobixibat 10mg
- Where
- Japan
- Volunteers
- 40 people
- Sponsor
- Yokohama City University
Spinal Cord Injuries, Neurogenic Bowel
Abdominal Functional Electrical Stimulation to Improve Bowel Function in Spinal Cord Injury
The primary objective of this study is to gather information about the effectiveness of abdominal FES to improve bowel management time (BMT) for people with chronic SCI.
- Trial name
- NCT06345781
- Testing
- Abdominal Functional Electrical Stimulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Craig Hospital
NAFLD, Fecal Microbiota
Dietary Counseling Coupled With FMT in the Treatment of Obesity and NAFLD - the DIFTOB Study
There are several studies performed to reveal the linkage between diet, fecal microbiota, and obesity. Human fecal microbiota transplantations in this asset are still scarce.
- Conditions
- NAFLD, Fecal Microbiota, Gut Microbiota, Obesity
- Trial name
- DIFTOB (NCT05607745)
- Where
- 3 sites in Finland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Gastrointestinal Tolerance
A Double Blind Study on the Gastrointestinal Effects of Arabinoxylan (Leaf Fiber Extract).
The objective of this study is to investigate the effect on Arabinoxylan on gastrointestinal (GI) tolerance, bowel habits, and microbiota in adults.
- Trial name
- NCT04100460
- Testing
- 7.25 grams of Arabinoxylan leaf fiber extract, 14.5 grams of Arabinoxylan leaf fiber extract, Control - No Arabinoxylan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Comet Bio Inc.
Personalized Nutrition, Health Status
Personalized Nutrition Advice for Optimizing Dietary Habits and Metabolic Status
The alteration maintained over time of some metabolic processes, such as oxidative stress, low-grade inflammation, carbohydrate and lipid metabolism, and of the intestinal microbiota activity, can induce some chronic diseases…
- Conditions
- Personalized Nutrition, Health Status, Dietary Habits
- Trial name
- PREVENTOMICS (NCT04641559)
- Testing
- Personalized nutrition group, Personalized Plan group, Control group
- Where
- Spain
- Volunteers
- 193 people, healthy volunteers welcome
- Sponsor
- Technological Centre of Nutrition and Health, Spain
Dyschesia
Study Assessing the Efficacy of Eductyl® for the Treatment of Patients With Dyschesia
The purpose of this study is to assess the efficacy of Eductyl versus placebo for treatment of patients with dyschesia.
- Trial name
- EDUCDYS (NCT01243723)
- Testing
- Eductyl suppository
- Where
- France
- Volunteers
- 306 people
- Sponsor
- Laboratoires Techni Pharma
Chronic Constipation
Effectiveness and Safety of Probiotic in Regulating Chronic Constipation
To evaluate the effectiveness and safety of the use of probiotics as food supplements in regulating the intestinal habit of subjects with chronic constipation, in comparison with placebo.
- Trial name
- NCT05980988
- Testing
- Probiotic
- Where
- 2 sites in Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Wecare Probiotics Co., Ltd.
Colorectal Cancer, Diet Habit
Walnuts and Colon Health (The WellNut Trial)
The purpose of this research study is to examine whether adding walnuts to your diet can have a beneficial effect on the gut bacteria population, inflammatory markers in the blood, and the tissue that lines the inside of the…
- Trial name
- NCT05195970
- Testing
- Walnuts
- Where
- 2 sites in United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- UConn Health
Slow Transit Constipation, Surgery
STOPS Trial: Total vs Subtotal Colectomy for Slow Transit Constipation
Total colectomy with ileorectal anastomosis is a traditional surgical option for slow transit constipation (STC). Subtotal colectomy with caecorectal anastomosis have been reported to be a potential alternative approach.
- Trial name
- NCT05352074
- Testing
- Total colectomy with ileorectal anastomosis, Subtotal colectomy with cecal-rectal anastomosis
- Where
- 14 sites in China
- Volunteers
- 252 people
- Sponsor
- Third Military Medical University
Appendicitis, Appendectomy
Re-assessment of Appendicitis Evaluation During Laparoscopic Appendectomy, Peritoneal Irrigation During Laparoscopic Appendectomy Does the Grade of Contamination Matter?
Type: prospective observational multicenter trial. Population of interest: adult patients undergoing laparoscopic appendectomy for acute appendicitis.
- Trial name
- RESIDENT1 (NCT05075252)
- Testing
- laparoscopic lavage
- Where
- Italy
- Volunteers
- 1,067 people
- Sponsor
- Niguarda Hospital
Postoperative Bowel Functions
Preoperatively Walking's Effect of Postoperative Bowel Functions in Patient With Gynecologic Cancer.
Preoperative walking's effect of postoperative bowel functions ASA 1 or 2 in patient with gynecologic cancers.
- Trial name
- NCT03553121
- Testing
- walking
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Irritable Bowel Syndrome, Microbial Colonization
Microbiota Profiling in IBS
This study investigates differences in microbiota profiles and metabolite levels between mild and severe IBS patients, compared to matched healthy controls. Two fecal samples, with one month in between, will be analyzed.
- Conditions
- Irritable Bowel Syndrome, Microbial Colonization, Dietary Habits
- Trial name
- IBSQUtrition (NCT03720314)
- Testing
- NA observational study
- Where
- Netherlands
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Morbid Obesity, Anorectal Diseases
GLP-1 Receptor Agonists and Early Proctologic Effects in Morbid Obesity
Prospective observational cohort study evaluating the early proctologic effects of GLP-1 receptor agonist therapy in morbidly obese patients.
- Conditions
- Morbid Obesity, Anorectal Diseases, Drug-Related Side Effects and Adverse Reactions, Constipation
- Trial name
- GLP-PROCT (NCT07668765)
- Testing
- GLP-1 receptor agonist therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Gazi University
Gynecologic Nursing, Pain
The Effect of Chewing Gum and Hot Compresses on Gynecologic Oncologic Surgery
The passage discusses the recovery of gastrointestinal (GI) function after abdominal surgery and the potential impact on patient comfort.
- Trial name
- NCT06196138
- Testing
- Gum, Hot Compress
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Spinal Cord Injuries, Constipation
Trancutaneous Abdominal Stimulation on Bowel Function.
This is a prospective, single-center, feasibility study to determine the sensations elicited by non-invasive abdominal electrical stimulation and its effects on bowel function in spinal cord injured individuals and in able-bodied…
- Trial name
- NCT04627168
- Testing
- Non-invasive, surface electrical stimulation device, DS5 Digitimer
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Amol Soin, M.D., MBA