Clinical trials: Bowel Resection
Erectile Dysfunction, Sigmoid Colon Cancer
Efficacy of Udenafil After Radical Resection for Sigmoid Colon and Rectal Cancer
The purpose of this study is to evaluate the efficacy of Udenafil (Zydena®, Dong-A Pharmaceutical co., Ltd, Seoul, Korea) in treatment of erectile dysfunction after radical resection for sigmoid colon and rectal cancer.
- Conditions
- Erectile Dysfunction, Sigmoid Colon Cancer, Rectal Cancer
- Trial name
- NCT00607282
- Testing
- Udenafil
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Seoul National University Hospital
Colon Polyp
Endocuff Vision Assisted vs. Standard Polyp Resection in the Colorectum
Adenomas are premalignant polyps of the colon that should be resected endoscopically. Complete resection of adenomatous polyps is the major task of colonoscopy.
- Trial name
- EVASTA (NCT03117114)
- Testing
- Endocuff Vision assisted polypectomy, Standard polypectomy
- Where
- Germany
- Volunteers
- 250 people
- Sponsor
- Technical University of Munich
Postoperative Pain After Laparoscopic Liver Resection
Intraoperative Continuous Lidocaine Infusion in Laparoscopic Liver Surgery
The goal of this clinical trial is to learn about effect of intraoperative continuous lidocaine infusion on postoperative pain, gut function and insulin resistance in patients undergoing laparoscopic liver surgery in adults.
- Trial name
- ICLIL (NCT07012889)
- Testing
- lidocaine infusion
- Volunteers
- 94 people
- Sponsor
- Medical University of Warsaw
Rectal Cancer
Preoperative Prediction Model of Pathological Outcomes (Mesorectum Quality and Positive Circumferential Resection Margin) in Patients With Mid-low Rectal Cancer
Elaboration of a preoperative prediction model of the quality of the mesorectum and the involvement of the circumferential margin in patients with mid-low rectal cancer who undergo laparoscopic anterior rectal resection.
- Trial name
- PREMARE (NCT03107650)
- Testing
- Transanal total mesorectal excision of rectal cancer
- Where
- Spain
- Volunteers
- 323 people
- Sponsor
- Pere Planellas Giné
Stage II Colon Cancer, Stage III Colon Cancer
Exercise and Colon Cancer
Despite the success of surgery and chemotherapy among people with colon cancer, 30-50% of patients develop recurrent disease. Physical activity has emerged as a potential lifestyle intervention to reduce cancer recurrence and…
- Trial name
- NCT02250053
- Testing
- Exercise
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Colorectal Cancer
Radial Reload Laparoscopic LAR Case Series
To evaluate the Radial Reload Stapler during laparoscopic low anterior resection (LAR) or anterior proctosigmoidectomy for rectal cancer by assessing the primary and secondary endpoints.
- Trial name
- NCT01706822
- Testing
- Covidien Radial Reload Stapler with Tri-Staple Technology
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Medtronic - MITG
Crohn Disease (CD), Crohn Disease of Ileum
Laparoscopic Right Hemicolectomy for Crohn's Disease of the Terminal Ileum Utilizing the Mesenteric Excision and Exclusion
This study is designed for patients requiring surgery for Crohn's disease of the terminal ileum. A combination of laparoscopic segmental right colectomy with extended mesenteric excision and the Kono-s anastomosis will be…
- Conditions
- Crohn Disease (CD), Crohn Disease of Ileum, Kono S Anastomosis, Extended Mesenteric Excision
- Trial name
- NCT07231601
- Testing
- Mesenteric excision and exclusion
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tzaneio General Hospital
Colonic Polyps
Detect InSpect ChAracterise Resect and Discard 2
Bowel cancer is a common disorder in the UK. Most cancers happen when a type of polyp, called an adenoma, becomes cancerous. Polyps are growths in the large bowel that can be cancerous, non-cancerous, or pre-cancerous (adenoma).
- Trial name
- DISCARD2 (NCT01603927)
- Testing
- Narrow band imaging for 'optical diagnosis' of colonic polyps (Olympus).
- Where
- 5 sites in United Kingdom
- Volunteers
- 2,500 people
- Sponsor
- South Tyneside and Sunderland NHS Foundation Trust
Colorectal Cancer, Colorectal Liver Metastases
Adjuvant FOLFIRI Based-chemotherapy After Resection of CLM Responding to Preoperative FOLFIRI
Eligible patients are patients with contraindication to preoperative oxaliplatin based-chemotherapy who underwent resection of no more than 10 colorectal liver metastases after preoperative FOLFIRI based chemotherapy with or…
- Trial name
- IRIMAD (NCT06501482)
- Testing
- Postoperative reintroduction of FOLFIRI based chemotherapy
- Where
- France
- Volunteers
- 254 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Liver Transplant Surgery, Colorectal Cancer Metastatic
Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection
Liver transplantation (LT) has become an accepted treatment for selected patients with unresectable liver metastases due to colorectal cancer (CRLM).
- Conditions
- Liver Transplant Surgery, Colorectal Cancer Metastatic, Colon Cancer Liver Metastases
- Trial name
- CLEAR (NCT06698146)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Northwestern University
Endoscopic Resection, Rectal Tumor
A Comparison of Endoscopic Synchronous Injection and Submucosal Dissection(ESISD) and Conventional Endoscopic Submucosal Dissection(CESD) for Granular Mixed Nodular Laterally Spreading Tumor in the Rectum (LST-G-M)
What is the study about? This study introduces and evaluates a new endoscopic technique called Endoscopic Synchronized Injection and Submucosal Dissection (ESISD).
- Trial name
- ESISD vs CESD (NCT07236827)
- Testing
- Endoscopic Synchronous Injection and Submucosal Dissection(ESISD), Conventional Endoscopic Submucosal Dissection(ESD)
- Volunteers
- 60 people
- Sponsor
- Taihe Hospital
Rectal Prolapse
Swedish Rectal Prolapse Trial
Rectal prolapse is a medical condition where rectum is protruding through the anal opening. The treatment is by surgery that can be performed with an anterior approach through the abdomen or a posterior perineal approach.
- Trial name
- NCT04893642
- Testing
- Suture rectopexy, resection rectopexy, Delorme's operation
- Where
- 12 sites in Sweden
- Volunteers
- 134 people
- Sponsor
- Danderyd Hospital
Cancer Metastatic to the Liver, Hepatocellular Carcinoma
A Study to Assess PV-10 Chemoablation of Cancer of the Liver
This open-label study will evaluate the safety, tolerability, pharmacokinetics and effect on tumor growth following a single intralesional injection of PV-10 in subjects with either (a) hepatocellular carcinoma (HCC) that is not…
- Conditions
- Cancer Metastatic to the Liver, Hepatocellular Carcinoma, Metastatic Melanoma, Metastatic Ocular Melanoma
- Trial name
- NCT00986661
- Testing
- PV-10 (10% rose bengal disodium)
- Where
- 5 sites in United States
- Volunteers
- 78 people
- Sponsor
- Provectus Biopharmaceuticals, Inc.
Inflammatory Bowel Diseases
Pre-operative Nutrition for Elective Resection Surgery in Inflammatory Bowel Disease
This study aims to determine if improved risk stratification tools and interventions to mitigate malnutrition reduce postoperative risk in patients undergoing elective or emergent resection surgery for inflammatory bowel disease…
- Trial name
- NCT06309017
- Testing
- Nutrition specialist, Ensure Surgery Immunonutrition shakes
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health
Cancer Colorectal
ctDNA Methylation Application in Postoperative Relapse and Adjuvant Chemotherapy Efficacy Evaluation
In this study, the investigators aimed to apply their previously developed multi-locus blood-based assay targeting circulating tumor DNA methylation to monitor postoperative relapse and evaluate adjuvant chemotherapy efficacy in…
- Trial name
- NCT05536089
- Testing
- a multi-locus blood-based assay
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Singlera Genomics Inc.
Colonic Neoplasms
Double Blinded Randomized Clinical Trial of the Effect of Open Versus Laparoscopic Colectomy on Neutrophils in Patients With Colon Cancer
The purpose of this study is: to determine neutrophil activity in patients with colon cancer, to determine levels sFas, sFasL and IL - 17 in serum of healthy volunteers and colon cancer patients and establish its prognostic…
- Trial name
- NCT00860691
- Testing
- Therapeutic conventional colorectal surgery, Therapeutic laparoscopic colorectal surgery, Peripheral blood sampling and performing: ELISA test of sFas, sFasL, IL - 17 and Bursttest
- Where
- Croatia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital Dubrava
Colorectal Cancer, Colorectal Cancer Metastatic
Comprehensive Genomic Profiling of Colorectal Cancer Patients With Isolated Liver Metastases to Understand Response & Resistance to Cancer Therapy
This is a prospective study investigating the disease course of patients with colorectal cancer that have had their cancer spread to their liver.
- Conditions
- Colorectal Cancer, Colorectal Cancer Metastatic, Hepatic Metastases
- Trial name
- COMPARISON (NCT03364621)
- Where
- 2 sites in Canada
- Volunteers
- 17 people
- Sponsor
- University Health Network, Toronto
Colorectal Cancer, Liver Metastasis Colon Cancer
Fluorescence-guided Resection Of Colorectal Liver Metastases Using SGM-101 and Indocyanine GREEN
This will be the first trial testing the feasibility of working simultaneously with the two fluorescent dyes ICG and SGM-101 in 10 patients with colorectal metastases.
- Conditions
- Colorectal Cancer, Liver Metastasis Colon Cancer, Image
- Trial name
- FOCUS GREEN (NCT05965817)
- Testing
- SGM-101 op top of ICG
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Leiden University Medical Center
Adenoma, Colorectal Neoplasms
Conventional Endoscopic Mucosal Resection vs Underwater Resection for Colorectal Non-pedunculated Colorectal Lesions
Randomized, comparative and prospective study between Conventional Endoscopic Mucosal Resection for the removal of flat or sessile colorectal lesions without previous attempt to resection.
- Trial name
- NCT03021135
- Testing
- Conventional Endoscopic Mucosal Resection, Underwater Endoscopic Mucosal Resection
- Where
- Brazil
- Volunteers
- 105 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Rectal Cancer, Organ-Space Surgical Site Infection
Organ/Space Surgical Site Infection and Recurrence and Survival in Rectal Cancer Surgery
In rectal cancer surgery, the organ/space surgical site infection (O/S-SSI) has an impact on patient's prognosis. Its influence in the oncologic outcomes remains controversial.
- Trial name
- VINCat_PDO_2 (NCT06382415)
- Where
- Spain
- Volunteers
- 3,826 people
- Sponsor
- Hospital de Granollers