Clinical trials: Bowel Surgeries
Ilues
Influence of Coffee Intake on Postoperative Bowel Function After Comprehensive Staging Surgery for Gynecological Malignancies: A Randomized Controlled Trial.
A delay in the return of normal bowel function with the passage of flatus and feces is one of the most important factors affecting early recovery and discharge in patients undergoing open complete staging surgery for…
- Trial name
- NCT01990482
- Testing
- caffe, Water
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people
- Sponsor
- Erzincan Military Hospital
Inflammatory Bowel Diseases
Treatment Outcomes of Advanced Neoplasia in IBD
In this study, we aimed to (1) compare cumulative incidences of synchronous and metachronous colorectal neoplasia as well as mortality following AN in CD and UC patients who underwent proctocolectomy, (sub)total colectomy…
- Trial name
- NCT05674773
- Testing
- Endoscopic or surgical resection
- Where
- Netherlands
- Volunteers
- 189 people
- Sponsor
- Radboud University Medical Center
Small Bowel Obstruction, Small Bowel Adhesion
Short and Prolonged Conservative Treatment in Patients With Adhesive Intestinal Obstruction
This study will compare the results of 24 h conservative treatment and N h conservative treatment of adhesive small bowel obstruction (where N = 72 h minus duration of intestinal obstruction).
- Trial name
- NCT05841069
- Testing
- Adhesiolysis, X-ray examination, Conservative treatment
- Where
- 4 sites in Russia
- Volunteers
- 180 people
- Sponsor
- North-Western State Medical University named after I.I.Mechnikov
Low Anterior Resection Syndrome
International Low Anterior Resection Score Evaluation
Aim: The aim of this study is to perform a prospective, international 4 months cohort study evaluating bowel function before curative rectal cancer surgery and one year after the surgery using the LARS score.
- Trial name
- PrePostLARS (NCT04040842)
- Testing
- Patients undergoing low anterior resection
- Where
- Lithuania
- Volunteers
- 400 people
- Sponsor
- National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos
Colorectal Neoplasms
Using Multimodal Prehabilitation to Improve Outcomes for Frail Patients Undergoing Resection of Colorectal Cancer
The purpose of this study is to determine if a program of physical activity, nutritional supplements and relaxation techniques is effective at decreasing post operative complications in frail colorectal cancer patients undergoing…
- Trial name
- NCT02502760
- Testing
- Physical Exercise Program, Whey Protein Isolate Powder, Relaxation Techniques
- Where
- 2 sites in Canada
- Volunteers
- 120 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Microbial Substitution, Tryptophan Metabolism Alterations
Impact of Gut Microbiota and Tryptophan Metabolites on Acute Pain in Lumbar Disc Herniation Surgery Patients
It is well-established that the gut microbiota plays a crucial role in various pain mechanisms, including visceral pain, inflammatory pain, headache, neuropathic pain, and opioid tolerance.
- Conditions
- Microbial Substitution, Tryptophan Metabolism Alterations, Postoperative Pain, Acute
- Trial name
- NCT06502223
- Testing
- Pain Perception in Patients Undergoing Lumbar Disc Herniation Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Dokuz Eylul University
Adult Acute Lymphoblastic Leukemia in Remission, Adult B Acute Lymphoblastic Leukemia
Dasatinib in Treating Patients With Solid Tumors or Lymphomas That Are Metastatic or Cannot Be Removed By Surgery
This phase I trial studies the side effects and best dose of dasatinib in treating patients with solid tumors or lymphomas that are metastatic or cannot be removed by surgery.
- Conditions
- Adult Acute Lymphoblastic Leukemia in Remission, Adult B Acute Lymphoblastic Leukemia, Adult Hepatocellular Carcinoma, Adult Nasal Type Extranodal NK/T-Cell Lymphoma
- Trial name
- NCT00608361
- Testing
- Dasatinib, Pharmacological Study
- Where
- 23 sites in United States
- Volunteers
- 80 people
- Sponsor
- National Cancer Institute (NCI)
Advanced Malignant Neoplasm, Colorectal Cancer
The Real Clinical Background of Advanced Colorectal Cancer Treatment Situation Survey
Collect the real clinical background of advanced colorectal cancer c of China.
- Trial name
- Sprit (NCT01549067)
- Where
- 2 sites in China
- Volunteers
- 3,700 people
- Sponsor
- Chinese Medical Doctor Association
Colon Cancer
Implementation of Laparoscopy-assisted Surgery for Colon Cancer
The purpose of this study is to study the implementation of laparoscopy-assisted surgery for cure of colon cancer in daily surgical practice.
- Trial name
- NCT01326065
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Helse Stavanger HF
Bowel Surgery, Emergency Abdominal Surgery
COMPARATIVE OUTCOME OF EARLY AND STANDARD ORAL FEEDING AFTER EMERGENCY BOWEL SURGERY
Informed consent will be obtained from patients or their legal representatives in cases where the patient is unconscious. Patient information, including names, ages, gender, smoking history, comorbidities, and the indication for…
- Conditions
- Bowel Surgery, Emergency Abdominal Surgery, ERAS
- Trial name
- NCT07047729
- Testing
- Early oral feeding, Standard oral feeding
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dr Hamail Khanum
Rectal Fistulas
FISTULA-RFA Trial: Radiofrequency Ablation for Perianal Fistula
The goal of this pilot clinical study is to learn whether radiofrequency ablation (RFA) can safely and effectively treat perianal fistulas in adults.
- Trial name
- FISTULA-RFA (NCT07452666)
- Testing
- Radiofrequency Ablation (RFA) for Perianal Fistula
- Volunteers
- 80 people
- Sponsor
- Korea University Ansan Hospital
Ulcerative Colitis, Surgery
Energy Expenditure in Patients With Ulcerative Colitis Undergoing Surgery
A prospective observational study to assess the energy needs of Ulcerative Colitis patients undergoing total proctocolectomy with ileoanal j-pouch anastomosis.
- Trial name
- NCT06221995
- Testing
- Indirect Calorimetry
- Where
- Greece
- Volunteers
- 30 people
- Sponsor
- Evangelismos Hospital
Triple Negative Breast Cancer
A Study Evaluating Safety and Efficacy of the Addition of ABT-888 Plus Carboplatin Versus the Addition of Carboplatin to Standard Chemotherapy Versus Standard Chemotherapy in Subjects With Early Stage Triple Negative Breast Cancer
This is a 3 arm Phase 3 study to evaluate the safety and efficacy of the addition of veliparib plus carboplatin versus the addition of carboplatin to standard neoadjuvant chemotherapy versus standard neoadjuvant chemotherapy in…
- Trial name
- NCT02032277
- Testing
- Cyclophosphamide, Doxorubicin, Paclitaxel
- Where
- 158 sites in United States, Australia and 13 more
- Volunteers
- 634 people
- Sponsor
- AbbVie
Hemorrhoid, Peri Anal Fistula
Discharge Conditions of Spinal Anesthesia With Heavy Prilocaine-Fentanyl and Heavy Bupivacaine-Fentanyl
In this prospective randomized study the investigators aimed to investigate difference of the duration of spinal anesthesia, discharge times and efficacy between low dose heavy Prilocaine-Fentanyl and heavy Bupivacaine-Fentanyl…
- Trial name
- NCT01880775
- Testing
- Prilocaine, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Diskapi Teaching and Research Hospital
Acute Appendicitis
MANAGEMENT OF APPENDICITIS DURING THE COVID-19 PANDEMIC
During the Covid-19 pandemic, non-operative management for acute appendicitis (AA) was implemented in the UK. The aim of this study was to determine the efficacy and outcomes of conservative versus surgical management of AA…
- Trial name
- observational (NCT04615728)
- Testing
- laparoscopic or open appendicectomy
- Where
- United Kingdom
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Hemorrhoids
Evaluation of the Analgesic Efficacy of an Ultrasound-guided Transperineal Pudendal Block in Outpatient Hemorrhoidal Surgery
In a population of patients undergoing hemorrhoidal surgery under general anesthesia and divided into two equal groups based on the method used for intraoperative pudendal nerve block and its branches in the ischioanal fossa…
- Trial name
- BACH (NCT07015775)
- Testing
- Neurostimulation, Ultrasound
- Where
- France
- Volunteers
- 202 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Heart Valve Surgery
Characterizations of Gut Microbiota and Postoperative Sleep in Patients Undergoing Heart Valve Surgery With Cardiopulmonary Bypass
The investigators designed a study to assess whether there is any change in gut microbiota and postoperative sleep before and after heart valve surgery with cardiopulmonary bypass.
- Trial name
- NCT05136001
- Testing
- polysomnography
- Where
- China
- Volunteers
- 36 people
- Sponsor
- China Medical University, China
Rectal Cancer
No Operation After Short Course Radiotherapy Followed By Consolidation Chemotherapy In Locally Advanced Rectal Cancer
This study is designed to explore the hypothesis that in patients with a Locally advanced rectal cancer (LARC) treated with a Total neoadjuvant therapy (TNT) strategy based on short course radiotherapy (5x5Gy) followed by…
- Trial name
- NOAHS-ARC (NCT04864067)
- Testing
- Oxaliplatin, 5-Fluoracil, Leucovorin
- Where
- 3 sites in Chile
- Volunteers
- 39 people
- Sponsor
- Servicio de Salud Metropolitano Sur Oriente
Colorectal Cancer, Anaesthesia
Cardiopulmonary Exercise Testing and Preoperative Risk Stratification
The investigators would like to evaluate the use of cardiopulmonary exercise tests (CPX) in guiding the care pathway of patients undergoing colorectal operations.
- Conditions
- Colorectal Cancer, Anaesthesia, Critical Illness
- Trial name
- NCT00737828
- Testing
- Perioperative care pathway guided by CPX results
- Where
- 3 sites in United Kingdom
- Volunteers
- 228 people
- Sponsor
- University College London Hospitals
Metastatic Colorectal Carcinoma, Metastatic Lung Small Cell Carcinoma
M6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
This phase I trial studies the side effects and best dose of M6620 and irinotecan hydrochloride in treating patients with solid tumors that have spread to other places in the body (metastatic) or cannot be removed by surgery…
- Conditions
- Metastatic Colorectal Carcinoma, Metastatic Lung Small Cell Carcinoma, Metastatic Malignant Solid Neoplasm, Metastatic Pancreatic Carcinoma
- Trial name
- NCT02595931
- Testing
- Berzosertib, Biopsy Specimen, Biospecimen Collection
- Where
- 23 sites in United States
- Volunteers
- 66 people
- Sponsor
- National Cancer Institute (NCI)