Clinical trials: Bra
Dietary Supplements
Effects of Genetic Variations in the Response to Brazil Nut Supplementation
This study investigates the effect of genetic variations after supplementation with Brazil nuts in healthy Brazilians. Briefly, all the participants will consume one nut a day for 2 months and will stop the intake for more 2…
- Trial name
- SUBRANUT (NCT03111355)
- Testing
- Brazil nut
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Child Nutrition Disorders
Nutritional Status, Food Intake and Fecal Microbiota of Brazilians Toddlers
Food intake pattern and lifestyle are associated with the nutritional status and intestinal microbiota composition, and such factors are important for the proper growth and development during early childhood, as well as for the…
- Trial name
- Nutrilife (NCT02950740)
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Danone Early Life Nutrition Brazil
Caregiver Burden of People With Dementia
Implementation of the START Intervention in Brazil: a Controlled Feasibility Trial
This controlled trial aims to assess the feasibility of a culturally adapted Brazilian version of the START (STrAtegies for RelaTives) program, a structured coping strategy program designed for family caregivers of people living…
- Trial name
- START/ESCADA (NCT07096960)
- Testing
- STrAtegies for RelaTives (START) - Brazilian version
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- Hospital Alemão Oswaldo Cruz
Chronic Kidney Diseases, Hemodialysis Complication
Clinical Outcomes of Hemodialysis in Brazil (COHEBRA): a Prospective Cohort Study
Introduction: Chronic kidney disease (CKD) is characterized by progressive decrease in glomerular filtration rate (GFR), eventually reaching the end-stage renal disease (ESRD) requiring renal replacement therapy (RRT).
- Trial name
- COHEBRA (NCT05273424)
- Where
- Brazil
- Volunteers
- 500 people
- Sponsor
- Catholic University of Pelotas
Apparent Resistant Hypertension, Hypertension
Rapid Management of Resistant Hypertension in the Public Health System (Fast Control)
This is a single-center, open-label, randomized clinical trial conducted at the Instituto Dante Pazzanese de Cardiologia, São Paulo, Brazil.
- Conditions
- Apparent Resistant Hypertension, Hypertension, High Blood Pressure
- Trial name
- FastControl (NCT07259733)
- Testing
- Triple Fixed-Dose Combination (Perindoprile/Indapamide/Amlodipine), Usual Care Antihypertensive Regimen
- Where
- Brazil
- Volunteers
- 142 people
- Sponsor
- Instituto Dante Pazzanese de Cardiologia
Breast Cancer
Patterns of Care in Hormone-receptor Positive, Advanced Breast Cancer
The purpose of this study is to characterize the current patterns of care for patients with hormone-receptor-positive, advanced breast cancer who have failed one prior endocrine therapy in Brazil.
- Trial name
- NCT01277926
- Where
- 6 sites in Brazil
- Volunteers
- 7 people
- Sponsor
- AstraZeneca
Colles' Fracture
SOLID-Effect of Risedronate Sodium at Distal Radius in Colle's Fracture.
The purpose of this study is to evaluate the efficacy and safety of risedronate sodium (Actonel®) after a wrist fracture in postmenopausal women.
- Trial name
- SOLID (NCT00460733)
- Testing
- Risedronate sodium, Calcium & Vitamine D3
- Where
- Brazil
- Volunteers
- 141 people
- Sponsor
- Sanofi
Tuberculosis
Xpert MTB/Rif, a New Tool for the Diagnosis of Pulmonary Tuberculosis in Two Municipalities in Brazil
Diagnosis of tuberculosis (TB) is a challenge because sputum smear, the most rapid and inexpensive test, often fails to detect the disease, in around 20 to 30% of cases.
- Trial name
- NCT01363765
- Testing
- Xpert MTB/Rif, Smear microscopy
- Where
- Brazil
- Volunteers
- 34,758 people
- Sponsor
- Ataulpho de Paiva Foundation
Congenital Heart Disease, Child Development
NeuroCardio Baby Research Outpatient Clinic: Study on the Neurodevelopment of Infants With Congenital Heart Disease in Brazil
The objective of this randomized clinical trial is to test the effectiveness of a low-cost hybrid remotely monitored parent-mediated and clinic-based multidisciplinary early intervention (EI) for low-income infants with CHD in…
- Conditions
- Congenital Heart Disease, Child Development, Early Intervention
- Trial name
- NCT05907109
- Testing
- Remotely monitored parent-mediated hybrid home and clinic based multidisciplinary Early Intervention protocols.
- Where
- 2 sites in Brazil
- Volunteers
- 300 people
- Sponsor
- Instituto de Cardiologia do Rio Grande do Sul
COPD (Chronic Obstructive Pulmonary Disease)
Prospective and Multicentric Cohort Study of Severe and Very Severe Chronic Obstructive Pulmonary Disease (COPD) in Brazil (SCOPe).
Chronic obstructive pulmonary disease (COPD) is prevalent (8-20%) and is one of the leading causes of mortality. In 2019 according to WHO it was the third highest cause of death worldwide.
- Trial name
- SCOPe (NCT06724315)
- Where
- Brazil
- Volunteers
- 693 people
- Sponsor
- Hospital Israelita Albert Einstein
Pneumonia
Errors in Prescription Antibiotics in Ventilator-associated Pneumonia
The infection is a major risk to hospitalized patients, especially those admitted to the Intensive Care Unit (ICU) and an unfavorable factor in the outcome of critically ill patients, increasing costs and prolonging…
- Trial name
- NCT02074033
- Where
- Brazil
- Volunteers
- 130 people
- Sponsor
- Federal University of Uberlandia
Tobacco Use Cessation, Tobacco Use Disorder
Text Messaging for Supporting Quit Attempts
This study is a preliminary research aimed to compare the feasibility and effectiveness of motivational interview (MI), Personalized text messages (TM) and usual care for outpatients, with focus on smoking cessation as the main…
- Trial name
- NCT02571244
- Testing
- Motivational Interview plus text message
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Federal University of Juiz de Fora
Parkinson Disease, Parkinsonism
Prodromal and Overt Parkinson's Disease Epidemiological Study in Brazil
Parkinson's Disease (PD) affects people universally, including all ethnic and socioeconomic groups, as a highly prevalent neurodegenerative disorder.
- Trial name
- PROBE-PD (NCT05677529)
- Where
- 4 sites in Brazil
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
COVID-19
Randomized Placebo-controlled Trial of Hydroxychloroquine in Outpatient Cases With Coronavirus Disease 2019 (COVID-19)
In December 2019, a group of patients with pneumonia of unknown cause was identified in Wuhan, in the Hubei province, China. Despite the need of target specific therapeutic options for COVID-19, until now there is no proof of…
- Trial name
- COALITION-V (NCT04466540)
- Testing
- Hydroxychloroquine
- Where
- 69 sites in Brazil
- Volunteers
- 1,372 people
- Sponsor
- Hospital Alemão Oswaldo Cruz
Implant Breast Reconstruction, TiLOOP® Bra Mesh
Bovine Pericardial Patch and TiLOOP® Bra Mesh in Immediate Implant Breast Reconstruction.
This study is the first randomized and controlled study assessing the efficacy and safety of bovine pericardial patch and TiLOOP® bra mesh in patients with immediate implant breast reconstruction
- Conditions
- Implant Breast Reconstruction, TiLOOP® Bra Mesh, Bovine Pericardial Patch
- Trial name
- NCT04245930
- Testing
- Bovine Pericardial Patch in Immediate Implant Breast Reconstruction, TiLOOP® Bra Mesh in Immediate Implant Breast Reconstruction
- Where
- China
- Volunteers
- 176 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Stroke
Matão Preventing Stroke (MaPS): a Stroke Register Study
Stroke is one of the most important cause of mortality and disability in Brazil. The city of Matão, located in São Paulo state, with a population around 80.000 inhabitants, has conditions to develop a community-based stroke…
- Trial name
- MaPS (NCT03391102)
- Testing
- Observational study
- Where
- Brazil
- Volunteers
- 840 people
- Sponsor
- Centro Neurológico de Pesquisa e Reabiitação, Brazil
Chronic Pain, Functional Limitations
Pain Evaluation and Treatment in Clinical Settings
This new research projet in pain is enrolled into an international official collaboration between researchers and clinicians from Irmandade da Santa Casa de Londrina (ISCAL) and those from two Quebec universities: University of…
- Conditions
- Chronic Pain, Functional Limitations, Musculoskeletal Disorders
- Trial name
- NCT05197777
- Testing
- tDCS associated to functional activities, Conservative physiotherapy
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Rubens da Silva
Syphilis Female
Trial Evaluating the Clinical Efficacy of Cefixime for Treatment of Early Syphilis in Non-pregnant Women
Hypotheses The antibiotic, Cefixime, for use in non-pregnant women with early syphilis will be efficacious and safe. Primary Objective The primary objective of the study is to demonstrate the efficacy, as measured by a 4 fold…
- Trial name
- NCT03752112
- Testing
- Cefixime, Benzathine penicillin 2.4 million units
- Where
- Brazil
- Volunteers
- 180 people
- Sponsor
- World Health Organization
Type 2 Diabetes
BE Study of the Fixed Dose Combination of 5 mg Saxagliptin and 500 mg Metformin HCl XR Tablet Relative to a 5 mg Saxagliptin (Onglyza™) Tablet and a 500 mg Metformin HCl XR (Glifage® XR Marketed in Brazil by Merck S.A.) Tablet Co-Administered to Healthy Subjects in the Fasted and Fed States
The purpose of this study is to demonstrate the bioequivalence (BE) of Saxagliptin and Metformin from a 5 mg Saxagliptin/500 mg Metformin extended release (XR) fixed dose combination (FDC) tablet relative to 5 mg Onglyza™ and 500…
- Trial name
- NCT01305551
- Testing
- Saxagliptin, Metformin XR, Saxagliptin/Metformin XR FDC
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- AstraZeneca
Breast Neoplasm Female
Evaluation of the Diagnostic Performance of a Bra Prototype to Detect Breast Cancer
Phi-Bra is a prospective and monocentric pilot study to assess the diagnostic capability of an innovative bra prototype to detect breast cancer, compared to the current standard of care: the mammography.
- Trial name
- Phi-Bra (NCT05574816)
- Testing
- Phi-Bra prototype measurements
- Where
- 2 sites in France
- Volunteers
- 45 people
- Sponsor
- Hospices Civils de Lyon