Clinical trials: Bra
Dengue Fever, Dengue Hemorrhagic Fever
Safety and Immunogenicity of a Tetravalent Dengue Vaccine in HIV-Positive Adults
The aim of the study was to evaluate the safety and immunogenicity of the Dengue vaccine in a population of special interest, such as HIV-positive adults previously exposed to dengue.
- Conditions
- Dengue Fever, Dengue Hemorrhagic Fever, Human Immunodeficiency Virus
- Trial name
- NCT02741128
- Testing
- CYD Dengue Vaccine
- Where
- 4 sites in Brazil
- Volunteers
- 133 people
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Hypertension, Blood Pressure
Matão Controlling Hypertension (MatCH Study): Rationale and Design
Background Hypertension is the main risk factor for most cardiovascular diseases. Blood pressure (BP) control has been shown to reduce the incidence of stroke, myocardial infarction, renal diseases and heart failure.
- Trial name
- MatCH (NCT03147092)
- Testing
- Captopril 25Mg, Hydrochlorothiazide 25Mg Oral Tablet,, Atenolol, Losartan potassium 50mg
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Centro Neurológico de Pesquisa e Reabiitação, Brazil
COVID-19, Convalescent Plasma
Convalescent Plasma Therapy for Hospitalized Patients With COVID-19
Plasma from donors who have recovered from coronavirus disease 2019 (COVID-19) contain antibodies to SARS-CoV-2 and may be a potential therapy for hospitalized patients with COVID-19.
- Conditions
- COVID-19, Convalescent Plasma, SARS-CoV-2, Pneumonia
- Trial name
- NCT05077930
- Testing
- Convalescent plasma, Standard of care
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- Tânia Portella Costa
Malaria
Artemether-lumefantrine for Treatment of P. Falciparum Malaria in Brazil
This is an in vivo evaluation of drug efficacy performed in Cruzeiro do Sul, in the state of Acre, Brazil. A total of 81 participants ≥5 years old with parasitological confirmation of P.
- Trial name
- NCT02600767
- Testing
- Artemether-lumefantrine combination
- Where
- Brazil
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Chronic Obstructive Pulmonary Disease (COPD), Asthma
Mitigating Chronic Respiratory Disease Through the Lens of Multimorbidity
The investigators aim to evaluate whether it is feasible for healthcare professionals to implement a case-finding tool to identify individuals at high risk for chronic respiratory diseases (CRDs) during routine care for…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Asthma, Preserved Ratio Impaired Spirometry
- Trial name
- MARES2 (NCT07093021)
- Where
- 2 sites in Brazil
- Volunteers
- 1,000 people
- Sponsor
- University College, London
COVID-19
Non-specific Effects of FLU-MMR Vaccines in Adults
Various observational studies have reported an association between influenza vaccination and lower rates of infection with SARS-Cov-2 and less COVID-19 disease severity have been reported in large epidemiological studies in US…
- Trial name
- FLUMMR-BRA (NCT05401448)
- Testing
- Influenza, MMR vaccines
- Where
- Brazil
- Volunteers
- 638 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Wound Healing Disorder, Post-Surgical Complication
NovoX®Cup as Primary Dressing After Breast Reduction
Breast reduction is one of the most frequently performed plastic surgeries. Studies have shown that breast reduction surgery significantly improves the patients' suffering and leads to a better health-related quality of…
- Conditions
- Wound Healing Disorder, Post-Surgical Complication, Mammaplasty
- Trial name
- NCT06420323
- Testing
- Treatment with NovoX® Cup, Treatment with Omnistrip®
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- MOSS S.p.A.
Diabetes Mellitus, Arterial Hypertension
Glycemic And Blood Pressure Control In Type 2 Diabetes, In A Primary Care Unit: A Staged Management Strategy
The aim of this study is to to analyze if it is possible to reach the goals of HbA1c <7.0% and blood pressure <= 130/80 mm Hg in a cohort of patients with type 2 diabetes attending a primary care unit, using ony those resources…
- Trial name
- NCT00935805
- Testing
- Metformin, Glybenclamide, NPH insulin
- Where
- Brazil
- Volunteers
- 124 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Hepatitis C, Chronic
ATHENAS - Retrospective Study of Compliance in Chronic Hepatitis C With Pegylated Interferon Alfa-2b/Ribavirin in Brazil (P05632)
This is a Phase 4, retrospective and observational, multicenter, national (Brazil), open, noncomparative, and nonrandomized study, which does not have visits. This study will be conducted in accordance to Good Clinical Practices.
- Trial name
- ATHENAS (NCT00856024)
- Testing
- Peginterferon alfa-2b, Ribavirin
- Volunteers
- 902 people
- Sponsor
- Merck Sharp & Dohme LLC
Hepatitis C Virus
Study to Describe the Actual Situation of Hepatitis C Treatment in Brazil
The purpose of the study is to describe: 1) the clinical profile, past and current management of participants with hepatitis C in Brazil reference centers; 2) the current situation about demographics characteristics, liver…
- Trial name
- PICTURE (NCT02773394)
- Where
- 8 sites in Brazil
- Volunteers
- 1,649 people
- Sponsor
- Janssen-Cilag Ltd.
Dietary Habits
Development of Online Store for Testing Regulatory Food and Nutrition Policies in Brazil
The purpose of this randomized controlled trial is to assess the impact of different nutrient profiles for magnifying glass front-of-package labels (FOPLs) on consumer choices in an online grocery store.
- Trial name
- NCT05789238
- Testing
- ANVISA, PAHO
- Where
- Brazil
- Volunteers
- 3,026 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Renal Insufficiency, Chronic
Bringing Knowledge About Chronic Kidney Disease in Brazil: Filling the Gap
This is a multicenter cross-sectional study will randomly screen kidney function in adult patients with known risk factors for chronic kidney disease (CKD) within the Brazilian general population.
- Trial name
- Filling gap (NCT07103629)
- Where
- Brazil
- Volunteers
- 8,428 people
- Sponsor
- AstraZeneca
Thyroid Cancer
Expanded Access Program With Lenvatinib for the Treatment of Differentiated Thyroid Cancer in Brazil
This is an Expanded Access Program to make lenvatinib available to participants with radioiodine-refractory differentiated thyroid cancer in Brazil.
- Trial name
- NCT03533361
- Testing
- Lenvatinib
- Where
- Brazil
- Sponsor
- Eisai Inc.
Breast Reconstruction After Mastectomy
National, Multicenter PMS Study "Patient Reported Outcome" in Breast Reconstruction Following Mastectomy With TiLOOP Bra
This multicentre, non-randomised, observational clinical device investigation will be performed to obtain postmarketing information on the TiLOOP® Bra and in particular on the improvement of the patients' quality of life as well…
- Trial name
- PRO-BRA (NCT01885572)
- Testing
- TiLOOP Bra
- Where
- 8 sites in Germany
- Volunteers
- 267 people
- Sponsor
- Pfm Medical Mepro Gmbh
Hiv, Adherence, Medication
Making ART Work Among Brazilian Youth
This study seeks to develop and pilot test a theory-based, integrated technology and counseling intervention to improve ART adherence among sexual and gender minority (SGM) young people living with HIV (ages 18-24) in Rio de…
- Trial name
- NCT06056037
- Testing
- Experimental: Making ART Work, Standard of Care
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Brown University
Substance Use Disorders, Contingency Management
Effectiveness of Contingency Management in the Treatment of Crack Addiction in Brazil
Crack addiction has become a severe public health problem in Brazil. Crack users present elevated prevalence rates of psychiatric comorbidities, sexual transmitted infections and unemployment with high probability of living or…
- Conditions
- Substance Use Disorders, Contingency Management, Addiction, Cocaine
- Trial name
- NCT03345394
- Testing
- Contingency Management, Standard treatment
- Where
- Brazil
- Volunteers
- 98 people
- Sponsor
- Federal University of São Paulo
Central Nervous System Infections
Device-related Central Nervous System Infections in Adult Intensive Care Units in Brazil
Resistant microorganisms are public health problems because they affect the treatment of infectious diseases and the survival of patients.
- Trial name
- IMPACTO-SNC (NCT06412523)
- Where
- 18 sites in Brazil
- Volunteers
- 554 people
- Sponsor
- Beneficência Portuguesa de São Paulo
Diabetic Retinopathy
Prevalence of Diabetic Retinopathy in São José do Rio Preto-SP-Brazil
Prevalence of Diabetic Retinopathy in São José do Rio Preto-SP-Brazil Abstract Objective: To determine the prevalence and characteristics of diabetic retinopathy (DR) among patients from São José do Rio Preto-SP-Brazil .
- Trial name
- NCT01131650
- Where
- Brazil
- Volunteers
- 710 people
- Sponsor
- Hospital do Olho Rio Preto
Hepatitis C
Hepatitis C Virus Self-testing (HCVST) in Sexual and Gender Minorities in Rio de Janeiro
Sexual and gender minorities (SGM), such as gay, bisexual and other men who have sex with men (MSM) and transgender women (TGW), are at high risk of HCV infection.
- Trial name
- NCT06203925
- Testing
- Hepatitis C virus self-test (oral fluid HCVST), Hepatitis C virus self-test (blood-based HCVST)
- Where
- Brazil
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Oswaldo Cruz Foundation
Patient and Surgical Related Risk Factors for Complications
TiLoop® Bra for Breast Reconstruction
A new approach for single stage implant based breast reconstruction (BR) is the use of a titanium-coated polypropylene mesh (TCPM) as an alternative to acellular dermal matrix (ADM).
- Trial name
- NCT01544023
- Volunteers
- 207 people
- Sponsor
- University of Rostock