Clinical trials: Bra
Menopause, Vasomotor Symptoms
A Survey About Hot Flashes in Women Going Through the Menopause
This study is an online survey of women in and around menopause with moderate to severe hot flashes. Menopause, a normal part of life, is a time after a woman's last period. Hot flashes often occur during menopause.
- Trial name
- NCT05083884
- Testing
- No Intervention
- Where
- United Kingdom
- Volunteers
- 2,176 people
- Sponsor
- Astellas Pharma Europe Ltd.
Malaria
Plasmodium Vivax Efficacy Trial in Cruzeiro do Sul, Acre, Brazil
Background: The World Health Organization recommends that antimalarial treatment policies be evaluated every few years to check their efficacy. P.
- Trial name
- NCT02043652
- Testing
- Chloroquine, Primaquine
- Where
- Brazil
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Centers for Disease Control and Prevention
Obsessive-Compulsive Disorder
Acceptance and Commitment Therapy (ACT) in Groups for Obsessive Compulsive Disorder: A Clinical Trial in Brazil
The goal of this clinical trial is to learn if Acceptance and Commitment Therapy (ACT) + Exposure and Response Prevention (ERP) in Group is effective to Obsessive Compulsive Disorder (OCD) in adults.
- Trial name
- NCT06548893
- Testing
- Group acceptance and commitment therapy (ACT)
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Universidade Federal do Paraná
Aortic Stenosis
Treatment of Aortic Stenosis in Brazil: Cost-Utility Analysis of TAVI vs SAVR
TEAM-Br is a randomized, prospective, cost-utility study comparing transcatheter aortic valve implantation (TAVI) versus surgical aortic vale replacement in Brazil.
- Trial name
- TEAm-BR (NCT04067089)
- Testing
- TAVR - Transcatheter aortic valve replacement, Surgical aortic valve replacement
- Where
- Brazil
- Volunteers
- 126 people
- Sponsor
- Hospital do Coracao
Public and Patient Involvement, Patient Participation
Use of Involvement Matrix in Cerebral Palsy Into Spain and Brazil
Application of Involvement Matrix in young people with Cerebral Palsy (GMFCS levels IV and V) from 12 to 17 years old with the purpose of improving the participation of this group in community leisure activities
- Conditions
- Public and Patient Involvement, Patient Participation, Family Research, Participation
- Trial name
- InMatrix-CP (NCT05214352)
- Testing
- co-design in the intervention manual elaboration to increase the participation in the community
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- University of Castilla-La Mancha
Executive Function
Brain Games to Improve Executive Function in São Paulo, Brazil
A growing body of research has highlighted the critical importance of children's self-regulation and executive function skills for their school performance as well as for their later life outcomes.
- Trial name
- NCT03491488
- Testing
- Brain Games
- Where
- Brazil
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Covid19, Corona Virus Infection
Nitazoxanide Therapy for Patients With COVID-19 Pneumonia
Multicenter, randomized, placebo-controlled, parallel, blinded, interventional, treatment clinical trial with two arms. Population: 500 Hospitalized patients with pneumonia derived from COVID-19 (Coronavirus Disease-19), either…
- Conditions
- Covid19, Corona Virus Infection, Pneumonia, Viral
- Trial name
- NCT04561219
- Testing
- Nitazoxanide
- Where
- Brazil
- Volunteers
- 500 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Metastatic Breast Cancer
Metastatic Breast Cancer in Brazil: Characterization of Patients and Treatments
The purpose of this study is to describe demographics and socioeconomics characteristics associated to the diagnosis of metastatic breast cancer in Brazil.
- Trial name
- NCT02662868
- Where
- 24 sites in Brazil
- Volunteers
- 767 people
- Sponsor
- Latin American Cooperative Oncology Group
Acute Coronary Syndromes, Heart Failure
Registry Of Acute meDical Emergencies in Brazil
Critical patients in emergency room are seriously situations that need quickly diagnosis and treatment. Different predictors of prognosis can be related with mortality and morbidity in-hospital and in long-term.
- Conditions
- Acute Coronary Syndromes, Heart Failure, Pulmonary Edema, Aortic Aneurysm, Familial Thoracic 1
- Trial name
- ROAD-Brazil (NCT02753023)
- Testing
- no intervention
- Where
- 6 sites in Brazil
- Volunteers
- 1,650 people
- Sponsor
- University of Sao Paulo General Hospital
Paraparesis Spastic Tropical
Use Of Valproid Acid To Treat Tropical Spastic Paraparesis/HTLV-1-Associated Myelopathy (TSP/HAM)
Is the valproic acid efficacy to treat TSP/HAM
- Trial name
- NCT00681980
- Testing
- Valproic acid, costicosteroids, valproid acid plus corticosteroids
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Mycobacterium Tuberculosis
A Cluster-Randomized Trial of DOTS vs DOTS Plus Active Case Finding
The purpose of the study is to see if one plan for identifying and treating tuberculosis (TB) works better than another in reducing new cases of TB.
- Trial name
- NCT00414882
- Where
- Brazil
- Volunteers
- 200,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Socioemotional Development, Cognitive Ability
Early Institutionalization Intervention Impact Project
The purpose of this study is to determine the effects of early intervention (placement into foster care, and a caregiving training) on physical, cognitive, social and brain development and psychiatric symptomatology in children…
- Conditions
- Socioemotional Development, Cognitive Ability, Behavioral and Neural Patterns of Attention, Brain Function
- Trial name
- EI-3 (NCT04165746)
- Testing
- Foster Care, Caregiving Intervention
- Where
- Brazil
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Neuroblastoma
Nutritional Status in Neuroblastoma in Sao Paolo, Brazil
This study proposes to investigate the effect of treatment of neuroblastoma on nutritional status, assessed by body mass index (BMI) z score, and body composition evaluated by mid-upper arm circumference (MUAC), from diagnosis…
- Trial name
- NCT03517280
- Where
- Brazil
- Volunteers
- 17 people
- Sponsor
- Columbia University
Covid19, SARS-CoV Infection
Brazilian Registry for Clinical Presentation of Individuals With COVID-19 (SARS-Brazil)
This is a registry-based cohort study of all adult patients (≥18 years) with confirmed or suspected SARS-CoV-2 infection. The main goal is to describe mortality incidence, demographic characteristics, coexisting conditions…
- Trial name
- SARS-Brazil (NCT04479488)
- Testing
- Hospital admission, Non-hospitalization procedures
- Where
- 14 sites in Brazil
- Volunteers
- 1,587 people
- Sponsor
- Hospital Israelita Albert Einstein
Diphtheria
A Post-marketing, Observational, Retrospective Study to Assess the Safety of RefortrixTM (Tdap) When Administered During Pregnancy in a Maternal Immunization Program in Brazil.
The purpose of this study is to assess the safety of RefortrixTM (Tdap) when administered during pregnancy in a maternal immunization program in Brazil.
- Trial name
- NCT02757950
- Testing
- Combined diphtheria, tetanus and tricomponent acellular pertussis vaccine [Refortrix (Tdap)]
- Where
- Brazil
- Volunteers
- 2,462 people
- Sponsor
- GlaxoSmithKline
COPD (Chronic Obstructive Pulmonary Disease)
Study That Will Evaluate the Brazilian Population With COPD.
Observational, prospective, multicenter cohort study with consecutive inclusion of COPD patients. Eligible patients will be those with severe and very severe COPD according to the GOLD 2024 (Global Initiative for Chronic…
- Trial name
- SCOPe (NCT06780046)
- Where
- 10 sites in Brazil
- Volunteers
- 693 people
- Sponsor
- AstraZeneca
Pulmonary Disease, Chronic Obstructive
Morbid Rates After Spiriva Chronic Obstructive Pulmonary Disease (COPD) Protocol Change
This study evaluates hospitalizations and mortality in patients with Chronic Obstructive Pulmonary Disease (COPD) before and after the implantation of a new COPD treatment plan (replacement of tiotropium soft mist inhaler for…
- Trial name
- NCT06053541
- Where
- Brazil
- Volunteers
- 3,015,000 people
- Sponsor
- Boehringer Ingelheim