Clinical trials: Bra
Zika Virus
Study on the Persistence of Zika Virus (ZIKV) in Body Fluids of Patients With ZIKV Infection in Brazil
The Zika infection is a viral disease that is transmitted to humans by the same mosquito that transmits Dengue and Chikungunya fever.
- Trial name
- ZikaBra (NCT03106714)
- Testing
- RT-PCR
- Where
- 3 sites in Brazil
- Volunteers
- 260 people
- Sponsor
- Oswaldo Cruz Foundation
Mother-Child Relations, Preterm Birth
The 2015 Pelotas (Brazil) Birth Cohort Study
This is the fourth birth cohort to be carried out in the city of Pelotas (Brazil) including more than 4 thousand children followed-up since the pre-natal period to study maternal-child health.
- Conditions
- Mother-Child Relations, Preterm Birth, Infant Development, Breast Feeding
- Trial name
- NCT03271723
- Testing
- Observational study
- Where
- Brazil
- Volunteers
- 4,275 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Multiple Myeloma
Multiple Myeloma (MM) Profile in Brazil: A Retrospective Observational Analysis
The purpose of this study is to present a descriptive analysis of demographic and clinical characteristics of the participants, as well as of the treatment patterns for multiple myeloma (MM) in Brazil.
- Trial name
- MMyBRave (NCT03506386)
- Testing
- No Intervention
- Where
- 17 sites in Brazil
- Volunteers
- 943 people
- Sponsor
- Takeda
Breast Cancer Patients
Breast Cancer BRAs Study (Breast Cancer Biomechanics of Radiotherapy And Surgery)
This study, delivered by Portsmouth Hospitals University NHS Trust in conjunction with the Research Group in Breast Health at the University of Portsmouth [1], aims to assess whether it is possible to test breast biomechanics in…
- Trial name
- NCT07135960
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Diagnosis, Oral, Periodontal Diseases
Study of Oral Conditions in Indigenous Populations in the State of Roraima - Brazil
The objective of this cross - sectional observational study will be to evaluate the oral conditions of indigenous people in the state of Roraima, comparing habits and hygiene conditions in each ethnicity evaluated.
- Conditions
- Diagnosis, Oral, Periodontal Diseases, Caries, Dental
- Trial name
- NCT03660410
- Testing
- Anamnesis, Oral clinical examination
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Universidade Metropolitana de Santos
Attention Deficit/Hyperactivity Disorder
Cost-effectiveness of the Treatment of Attention Deficit/Hyperactivity Disorder With Methylphenidate Immediate-release in Brazil
The first objective is to measure the QALYs (Quality Adjusted Life Years) of Brazilian children and adolescents, submitted to methylphenidate immediate-release treatment for Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- NCT01705613
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Dyslipidemia, Oxidative Stress
Brazil Nut Consumption in Microvascular Endothelial Function, Oxidative Stress and Metabolic Abnormalities
The purpose this research is to check the effect of Brazil Nuts consumption in oxidative stress, metabolic abnormalities and microvascular endothelial function dyslipidemic and hypertensive patients.
- Trial name
- NCT01990391
- Testing
- Brazil nut flour
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Short Bowel Syndrome (SBS)
Retrospective Study on Participants With Short Bowel Syndrome and Chronic Intestinal Failure That Underwent Transplantation in Brazil
The main aim of this study is to capture management and treatment outcome data in participants with short bowel syndrome and chronic intestinal failure (SBS-IF) that underwent intestinal transplantation in Brazil.
- Trial name
- NCT05113082
- Where
- Brazil
- Volunteers
- 7 people
- Sponsor
- Takeda
Diarrhea, Malnutrition, Other Nutritional Deficiencies
HIAS II - Study of Nutritional Supplementation in Hospitalized Children With Persistent Diarrhea or Malnutrition
This study will determine the effect of 7 days supplementation of alanyl-glutatime or glycine on the damaged intestinal barrier function on day 8 in children with persistent diarrhea or malnutrition.
- Trial name
- NCT00133562
- Testing
- Alanyl-glutamine, Glycine
- Volunteers
- 108 people
- Sponsor
- University of Virginia
Lymphoma, B-Cell
A Study to Evaluate Treatment Patterns and Investigate Adult Patients With B-cell Lymphoma
This is a retrospective observational registry study designed to characterise patient profiles, assess treatment patterns, evaluate clinical outcomes and explore COO testing patterns among adult patients with newly diagnosed…
- Trial name
- Clarity-BR (NCT07882576)
- Where
- 5 sites in Brazil
- Volunteers
- 532 people
- Sponsor
- AstraZeneca
Bioequivalence, Diabetes Mellitus, Type 2
Bioequivalence Study of Sitagliptin Hydrochloride / Metformin Hydrochloride Extended-release Film Coated Tablets 100 mg /1000 mg (FDC) in Healthy Adult Male and Female Subjects Under Fasting Conditions.
The objective of this study was to evaluate and compare the bioavailability and therefore to assess the bioequivalence of two different formulations of sitagliptin/metformin extended release tablets after a single oral dose…
- Trial name
- NCT06124560
- Testing
- Sitagliptin/Metformin HCl 100/1000 mg extended release film-coated tablet
- Where
- Mexico
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Galenicum Health
Tobacco Use Cessation
Gender-Relevant Tobacco Cessation Among Women in Brazil
The overall goal of this renewal is three-fold: (1) to continue to sustain and strengthen the network; (2) to conduct a group randomized controlled trial to assess the efficacy of a theory-based, culturally- and gender-relevant…
- Trial name
- NCT03845413
- Testing
- Control, 12-home visits by the Community Health Worker + referring to an appointment for the participant to attend the tobacco cessation program
- Volunteers
- 338 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Pain, Disruption or Dehiscence of Closure of Sternum or Sternotomy
Use of a Support Bra to Reduce Pain and Improve Surgical Healing in Women Undergoing Sternotomy for Cardiac Surgery
The primary purpose of this study is to examine whether a properly fitted support bra on females improves their quality of life post-sternotomy. Specifically, does a support bra reduce discomfort, pain and wound dehiscence.
- Conditions
- Pain, Disruption or Dehiscence of Closure of Sternum or Sternotomy, Quality of Life
- Trial name
- NCT02453945
- Testing
- Adjustable Support Bra
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Heart Failure
Home Based Intervention Led by Nurse in Brazil
Home visits (HV) are one of the multidisciplinary approaches that has already shown to benefit the follow-up of Heart Failure (HF) patients.
- Trial name
- HFHELENI (NCT01213862)
- Testing
- Home Based Education
- Volunteers
- 200 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Adolescent Behavior
The "Fortaleça Sua Saúde" Program for Active and Healthy Lifestyle Among Brazilian Students
Background: Interventions on lifestyle among adolescents are important, but the main mechanisms that explain the changes (mediating variables) on lifestyle have been little explored.
- Trial name
- NCT02439827
- Testing
- "Fortaleça sua Saúde" program
- Volunteers
- 1,085 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Catarina
Accidental Falls
Multifactorial Falls Prevention Program - Brazil
This study is a clinical trial designed to evaluate the effectiveness of a multifactorial falls prevention program in reducing the rate of falls.
- Trial name
- NCT01698580
- Testing
- On-site exercise, home-based exercise, Educational and behavioural
- Where
- Brazil
- Volunteers
- 612 people
- Sponsor
- University of Sao Paulo
Diabetes Mellitus
Insulin Glargine Benefits in Japanese Pts Outside of Japan (US or Brazil)
To estimate the efficacy of combination therapy with Lantus plus Amaryl in controlling blood glucose in Japanese patients with type 2 diabetes having failed OAD therapy, and document the ability to preserve the endocrine…
- Trial name
- NCT00642915
- Testing
- Lantus, Amaryl
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Sanofi
Rotavirus Gastroenteritis
Study to Evaluate the Effectiveness of Rotarix™ Against Severe Gastroenteritis Among Hospitalized Children in Brazil
The purpose of this study is to estimate the effectiveness of 2 doses of Rotarix™ vaccination in preventing rotavirus severe gastroenteritis among children hospitalized in Belem area, Brazil.
- Trial name
- NCT01177657
- Testing
- Stool sampling
- Where
- Brazil
- Volunteers
- 1,944 people
- Sponsor
- GlaxoSmithKline
Cardiopulmonary Resuscitation, Educational Problems
Continuous Chest Compressions Training Among Schoolchildren With Gamification in Brazil: a Pilot Study
This study employed a randomized cluster intervention design to evaluate differences in chest compression depth among children's groups, using active learning methodologies and serious game-based learning as part of the Kids Save…
- Trial name
- CSC (NCT06565767)
- Testing
- cardiopulmonary resuscitation quality
- Where
- Brazil
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Photodamage, Photoaging
Efficacy and Safety of Oral Isotretinoin for Cutaneous Photodamage
This is a randomized, comparative, single evaluator-blinded trial to evaluate clinical, histological and immunohistochemical effects of oral isotretinoin plus moisturizer sunscreen as compared to the use of 0,05% tretinoin cream…
- Trial name
- NCT00842907
- Testing
- oral isotretinoin, Tretinoin
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo