Clinical trials: Bra
Dengue
Study to Evaluate the Incidence, Clinical Characteristics and Economic Burden of Dengue in Brazilian Children
The aim of this study is to establish an active surveillance in order to generate dengue disease burden estimates including incidence rates, prevalence data, clinical presentation and cost of illness in Forteleza (Brazil).
- Trial name
- NCT01391819
- Testing
- Data collection, Blood sample collection
- Where
- Brazil
- Volunteers
- 2,117 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Zika Virus, Zika Virus Infection
ZIKAlliance Natural History Study
Study to enroll up to 1000 adult patients (>18 years) presenting with febrile or rash illness of short duration (<72h) in designated clinics in the State of Sao Paulo, Brazil.
- Trial name
- ZIKAllianceNH (NCT03204409)
- Where
- Brazil
- Sponsor
- University of Heidelberg Medical Center
Efficacy of a Technique (Brassiere Sutures)
TPS After Upper Blepharoplasty
Increased tarsal platform show (TPS) and decreased brow fat span (BFS) are associated with favorable results in women undergoing cosmetic blepharoplasty.
- Trial name
- NCT02879552
- Testing
- Traditional upper blepharoplasty, Brassiere suture with blepharoplasty
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Instituto de Olhos de Goiania
Chronic Obstructive Pulmonary Disease (COPD), Asthma
Mitigating Chronic Respiratory Disease Through the Lens of Multimorbidity (MARES3)
The investigators aim to investigate how individuals attending primary healthcare (PHC) services in Brazil for treatment of non-communicable diseases (NCDs), identified there as having abnormal spirometry or as being at high risk…
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Asthma, Preserved Ratio Impaired Spirometry (PRISM)
- Trial name
- NCT07134855
- Where
- 2 sites in Brazil
- Volunteers
- 473 people
- Sponsor
- University College, London
Travel Health, Mobile Health Technology (mHealth)
TOURIST 2: Tracking Of Urgent Risks In Swiss Travelers
New mobile Health (mHealth) technology creates an opportunity to approach travel medicine research in a different way, revolutionising our understanding of risks to travellers.
- Conditions
- Travel Health, Mobile Health Technology (mHealth), Elderly Travelers, Chronic Diseased Travelers
- Trial name
- TOURIST2 (NCT03262337)
- Testing
- none, this is an observational study
- Where
- 2 sites in Switzerland
- Volunteers
- 793 people
- Sponsor
- University of Zurich
Hepatitis C, Chronic
A Retrospective Study to Assess the Impact of the Use of Interferon in Patients With Chronic Hepatitis C (DECISION)
This retrospective study will assess the sustained virologic response and the safety of two different interferons (pegylated or conventional) in patients with chronic hepatitis C. Data will be collected for 24 weeks.
- Trial name
- NCT01280656
- Testing
- Conventional Interferon, Peginterferon Alfa-2a, Peginterferon Alfa-2b
- Where
- 37 sites in Brazil
- Volunteers
- 660 people
- Sponsor
- Hoffmann-La Roche
Obesity
Brazil Nut Consumed on the Metabolic Profile, Oxidative Stress and Nutritive Microcirculatory Patterns
The purpose this research is to check if Brazil Nuts consumed improvement the metabolic profile, state redox and endothelial function in obese adolescents.
- Trial name
- NCT00937599
- Testing
- Brazil Nut
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Rio de Janeiro State University
Nutritional Therapy Quality
The Reality of Nutritional Therapy in Brazil: Quality Assessment
Nutritional status depletion is associated with complications such as increased morbidity and mortality, worsening of patients' quality of life and increased length of hospital stay.
- Trial name
- NCT03351621
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- Federal University of Minas Gerais
Cardiovascular Diseases, Myocardial Infarction
Real World Evidence Study of Statin Use in Brazil
A cross-sectional real-world data study designed to assess the use of statins in individuals assisted within the primary care system in Brazil.
- Conditions
- Cardiovascular Diseases, Myocardial Infarction, Stroke, Hypertension
- Trial name
- RWE-Statins (NCT05285085)
- Testing
- Statin
- Where
- Brazil
- Volunteers
- 2,133,900 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Endometrial Cancer
Molecular and Epidemiological Characteristics of Endometrial Cancer in Brazil
An evaluation of the molecular and epidemiological aspects of endometrial cancer in Brazil is necessary to understand the high frequency of advanced disease.
- Trial name
- MADONNA (NCT06014580)
- Testing
- Observational study
- Where
- 10 sites in Brazil
- Volunteers
- 276 people
- Sponsor
- Latin American Cooperative Oncology Group
Obstructive Sleep Apnea (OSA)
Cost-effectiveness Analysis of Home Polysomnography Made by Primary Care - (SONOPC Study)
The goal of this randomized clinical trial is to assess the cost-effectiveness of a home polyssomnography made by primary care compared to standard protocol for diagnosing obstructive sleep apnea in both genders.
- Trial name
- SONOPC (NCT07744880)
- Testing
- home polysomnography made by health professionals in primary care, Standard protocol
- Volunteers
- 60 people
- Sponsor
- Escola Superior de Ciencias da Saude
Registry
Real World Study of Deep Venous Thrombosis. Analysis of Prospective Cases in University Hospitals of São Paulo
Background: Deep venous thrombosis (DVT) is a common and important vascular disease due to its morbidity and mortality. Its incidence remains high throughout the world and constitutes serious problems for national and…
- Trial name
- DVT (NCT03388775)
- Testing
- deep venous thrombosis
- Where
- Brazil
- Volunteers
- 800 people
- Sponsor
- Fundação Faculdade Regional de Medicina de São José do Rio Preto
Covid
Covid-19 Data Analyses in Brazil
This descriptive study aims to describe the Brazilian scenario of patients hospitalized due to COVID-19 and to analyze the impact of COVID-19 on the Brazilian public health system.
- Trial name
- BRAVO (NCT06652451)
- Where
- Brazil
- Volunteers
- 361,000 people
- Sponsor
- AstraZeneca
Mild Cognitive Impairment
Brazil Nuts Effects on Selenium Status and Cognitive Performance
Some studies reported that selenium status is associated with cognitive function. However only a few reports have investigated whether selenium supplementation can benefit cognitive performance and in most of them selenium…
- Trial name
- NCT02121457
- Testing
- Brazil nut, selenium
- Where
- Brazil
- Volunteers
- 31 people
- Sponsor
- University of Sao Paulo
Radiotherapy Side Effect
Radiotherapy With Extreme Hypofractionation in Patients With Breast Cancer in Brazil: a Retrospective Cohort Study
The radiotherapy scheme with extreme hypofractionation has gained space in clinical practice and, therefore, it is necessary to analyze the Brazilian national experience in selected patients with breast cancer, with the aim of…
- Trial name
- RADIANT (NCT05776147)
- Where
- 11 sites in Brazil
- Volunteers
- 461 people
- Sponsor
- Latin American Cooperative Oncology Group
Treatment of Cutaneous Leishmaniasis in Brazil.
Trial of Miltefosine in Cutaneous Leishmaniasis (Brazil)
The hypothesis of this trial is that the therapeutic activity and safety of oral miltefosine in Brazilian patients with cutaneous leishmaniasis is similar or superior to the intravenous standard treatment (meglumine antimoniate …
- Trial name
- NCT00600548
- Testing
- Miltefosine., Meglumine antimoniate.
- Where
- 2 sites in Brazil
- Volunteers
- 180 people
- Sponsor
- Hospital Universitário Professor Edgard Santos
Helminthiasis
Bioavailability and Safety of Two Oral Fixed Dose Preparations Containing 18 mg Ivermectin (IVM 18 MG TABLETS, LICONSA S.A., Spain) Versus Reference Dosing (Weight Based) Containing 6 mg Ivermectin (REVECTINA®, Abbott Laboratórios do Brasil Ltda, Brazil)
Evaluation of the bioavailability and safety of one oral preparation containing fixed dose 18 mg ivermectin (IVM 18 MG TABLETS, LICONSA S.A., Spain) or two oral preparations containing fixed dose 18 mg ivermectin (IVM 36 MG…
- Trial name
- NCT03173742
- Testing
- T1, T2, T3, T1,T3,T2, T2,T1,T3
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Insud Pharma
Skin Cancer
Sunface Mirroring RCT in Brazil
Randomized trial looking at the effects of a behavioral photoaging software intervention on sunscreen use in the city of Itauna, Brazil.
- Trial name
- NCT03178240
- Testing
- photoaging mirroring intervention
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Giessen
HIV, Herpes Simplex 2
Improving Blood Safety and HIV Testing in Brazil
Conduct a randomized controlled trial (RCT) to test the hypothesis that offering client-centered HIV counseling and testing (HCT) to blood donor candidates will reduce the risk of HIV contamination in the blood supply and also…
- Conditions
- HIV, Herpes Simplex 2, Hepatitis C, Hepatitis B
- Trial name
- NCT01681420
- Testing
- HIV Counseling and Testing, Blood Donation
- Where
- Brazil
- Volunteers
- 11,900 people, healthy volunteers welcome
- Sponsor
- Vitalant Research Institute
COVID-19
The South Proxa-Rescue AndroCoV Trial Against COVID-19
The purpose of this study is to investigate the efficacy of proxalutamide or hospitalized moderate-to-severe COVID-19 patients.
- Trial name
- NCT05126628
- Testing
- Proxalutamide
- Where
- Brazil
- Volunteers
- 133 people
- Sponsor
- Corpometria Institute