Clinical trials: Brachial Plexus Blocks
Comparison of Onset Time
Onset Time of Brachial Plexus Block Using Local Anaesthetic Diluted With 0.9% Saline vs 5% Dextrose
Regional anesthesia employs the use of local anesthetics (LA) to block specific nerves to enable pain free surgery to be performed, or for intra and post operative pain relief.
- Trial name
- NCT01815944
- Testing
- 0.75% Ropivacaine, Normal saline, Dextrose 5%
- Where
- Malaysia
- Volunteers
- 55 people
- Sponsor
- University of Malaya
Arteriovenous Fistula, Arteriovenous Graft
A Randomised Trial Comparing Supraclavicular Block vs Supraclavicular and Pecs II Block in Arteriovenous Grafting
This study evaluates the addition of Pecs II block to ultrasound-guided supraclavicular brachial plexus block in patients undergoing arteriovenous graft creation surgery.
- Conditions
- Arteriovenous Fistula, Arteriovenous Graft, Kidney Failure, Chronic, Renal Failure, End-stage
- Trial name
- NCT02331030
- Testing
- Supraclavicular, Pecs II block, Ropivacaine 0.5% 20ml
- Where
- Singapore
- Volunteers
- 36 people
- Sponsor
- Changi General Hospital
Brachial Plexus Blocks
Perineural Dexamethasone, Dexmedetomidine, or Their Combination to Reduces Rebound Pain After Supraclavicular Brachial Plexus Block
Dexmedetomidine, an α2 adrenoceptor agonist, and dexamethasone, a potent anti-inflammatory steroid, are commonly used, effective, and safe adjuvants to peripheral nerve block (PNB).
- Trial name
- NCT07299877
- Testing
- Group A (Dexamethasone), Group B (Dexmedetomidine), Group C (Dexamethasone + Dexmedetomidine)
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Al-Azhar University
Shoulder Arthroscopy, Pain
Intravenous Dexamethasone on Supraclavicular Brachial Plexus Block for Shoulder Arthroscopy
Previous studies have confirmed that IV dexamethasone prolongs brachial plexus blocks. However, these studies only used fixed doses of IV dexamethasone at relatively high doses, which could potentially lead to increased glucose…
- Trial name
- SCB & IV Dex (NCT02688530)
- Testing
- IV Saline, IV Dexamethasone 4mg, IV Dexamethasone 6mg
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Brachial Plexus Blockade
Nociception Level Index After Brachial Plexus Block In Upper Extremity Surgery
The present prospective within-subject observational study will evaluate whether unilateral brachial plexus block (BPB) induces measurable lateralized autonomic modulation, assesses using bilateral Nociception Level (NoL)…
- Trial name
- NCT07620002
- Where
- Israel
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Smoking, Cigarette, Regional Anesthesia
Impact of Smoking on Ultrasound-Guided Infraclavicular Brachial Plexus Block Onset and Duration
The present study will be conducted involving 40 patients aged 18-65 years with ASA physical status I and II, scheduled for acute or elective hand or forearm surgery under the lateral infraclavicular block.
- Trial name
- NCT06755229
- Volunteers
- 40 people
- Sponsor
- Selcuk University
Analgesia, Acute Pain
Pharmacokinetic Analysis of Bupivacaine in the Presence and Absence of Perineural Dexamethasone in Axillary Blockade
The investigators will conduct a prospective, randomized, double-blinded study using an axillary brachial plexus block in patients undergoing elective surgery of the distal forearm and hand to characterize and describe the…
- Conditions
- Analgesia, Acute Pain, Upper Extremity Injury
- Trial name
- NCT05359731
- Testing
- Bupivacaine Hydrochloride, Bupivacaine Hydrochloride with Dexamethasone
- Where
- Chile
- Volunteers
- 20 people
- Sponsor
- University of Chile
Pericapsular Nerve Block, Interscalene Brachial Plexus Block
Comparison Between Pericapsular Nerve Group (PENG) Block and Interscalene Brachial Plexus Block for Postoperative Analgesia Following Shoulder Arthroscopy
The study aimed to compare ultrasound guided pericapsular nerve group (PENG) block versus interscalene brachial plexus block for postoperative analgesia following shoulder arthroscopy.
- Conditions
- Pericapsular Nerve Block, Interscalene Brachial Plexus Block, Shoulder Arthroscopy
- Trial name
- NCT06235879
- Testing
- Control Group (Interscalene brachial plexus block), Pericapsular nerve group (PENG) block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Acute Pain
Analgesic Effect of Liposomal Bupivacaine
Brachial plexus blocks (BPB) are commonly used to provide regional anaesthesia for patients undergoing distal radial fracture surgery.
- Trial name
- NCT05118399
- Testing
- Bupivacaine Injection [Marcaine], Bupivacaine Liposome 13.3 MG/ML [Exparel]
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- The University of Hong Kong
Analgesia
Analgesic Efficacy of Continuous Infusion of Local Anaesthetic Versus Single-shot Injection Interscalene Block
The aim of this study is to study the analgesic efficacy of a continuous infusion of local anaesthetics for interscalene brachial plexus block after major shoulder surgery in the setting of multimodal analgesia, in order to…
- Trial name
- BIGKIS (NCT04394130)
- Testing
- ropivacaine 0.2%
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Eric Albrecht
ESRD (End Stage Renal Disease)
Ultrasound-Guided T2 Erector Spinae Plane Block Versus Intercostobrachial Block in AV Fistula Surgery.
This study aims to determine whether ultrasound guided ESP block at 2nd thoracic vertebrae is non inferior to ultrasound guided ICBN block as adjunct to supraclavicular brachial plexus block in achieving complete sensory blockade…
- Trial name
- ICBN/ESP (NCT07754357)
- Testing
- Ultrasound Guided Intercostobrachial Nerve Block, Ultrasound Guided Erector Spinae Plane Block at T2 level
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Fatma Hatem Mokhtar
Shoulder Pain
Suprascapular and Axillary Blocks Versus Interscalene Block for Shoulder Surgery
The purpose of this study is to determine whether the combination of suprascapular and axillary nerve blocks is non-inferior to the conventional interscalene block (ISB) in providing pain relief during the first postoperative day…
- Trial name
- PASS (NCT02517437)
- Testing
- Suprascapular & axillary blocks, Interscalene block
- Where
- 2 sites in Canada
- Volunteers
- 130 people
- Sponsor
- University Health Network, Toronto
Shoulder Surgery, Obesity
Interscalene vs Phrenic-sparing Blocks in Obesity and Effect of Maximum Inspiratory Pressure
The goal of this clinical trial is to learn whether a phrenic-sparing nerve block can lower early breathing problems after shoulder surgery in adults with obesity, and whether a simple breathing-strength test (maximum inspiratory…
- Trial name
- NCT07216820
- Testing
- Ultrasound-Guided Interscalene Brachial Plexus Block, Phrenic-Sparing Block Combination (Experimental), Bupivacaine HCl 0.5% Injectable Solution
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of North Carolina, Chapel Hill
Wrist Disease, Hand Injuries and Disorders
Dexamethasone in Supraclavicular Brachial Plexus Block for Anesthesia After Pediatric Hand/Wrist Surgery
Effect of Systematic Dexamethasone on the Duration of Supraclavicular Brachial Plexus Block for Anesthesia After Pediatric Hand/Wrist Surgery
- Trial name
- NCT05887778
- Testing
- Sodium Chloride 0.9% Inj, 0,1mg/kg Dexamethasone, 0,2mg/kg Dexamethasone
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Anesthesia, Local, Postoperative Pain
Comparison of Supraclavicular and Costoclavicular Brachial Plexus Blocks in Pediatrics
In upper extremity surgeries, the brachial plexus block can be performed with different techniques at various levels depending on the proximal and distal level of the surgery.
- Trial name
- NCT04782778
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Rheumatoid Arthritis, Osteoarthritis
Low Dose Dexamethasone in Supraclavicular Blocks
Brachial plexus nerve blocks provide superior analgesia over opioids while avoiding unwanted side effects. Single shot blocks with local anesthetic alone usually do not last the duration of the acute post-surgical pain period.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Nerve Entrapment, Ligament Injury
- Trial name
- NCT02666443
- Testing
- Control intervention (no dexamethasone), Peri-neural Dexamethasone 1 mg, Intravenous Dexamethasone 1 mg
- Where
- Canada
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Pain, Postoperative, Liposomal Bupivacaine
Liposomal Bupivacaine Plus Plain Bupivacaine Versus Dexamethasone Plus Plain Bupivacaine in the Supraclavicular Brachial Plexus Block in Patients With Risk Factors for Severe Acute Postoperative Pain
The supraclavicular brachial plexus block (BPB) is a frequently used anaesthetic method for upper limb surgeries, including distal radial fracture surgery.
- Conditions
- Pain, Postoperative, Liposomal Bupivacaine, Dexamethasone, Supraclavicular Brachial Plexus Block
- Trial name
- NCT07665762
- Testing
- 10ml 0.5% plain bupivacaine with 10ml 1.33% liposomal bupivacaine, 19ml 0.5% plain bupivacaine with 1ml (4mg) dexamethasone
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The University of Hong Kong
Brachial Plexus Blockade
Concentration-Volume Relationship in Infraclavicular Block
This prospective, randomized, double blind study aims to determine the optimal volume for adequate sensorial and motor blockade following an infraclavicular block. Patients will be randomized into three groups.
- Trial name
- NCT02820688
- Testing
- Bupivacaine 0.25%, Prilocaine 1%, Infraclavicular Nerve Block
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Bozyaka Training and Research Hospital
Renal Failure
Assessment of the Sympathetic Nervous System Blockade of the Upper Limb After a Brachial Plexus Block in Patients With End Stage Renal Failure
The purpose of this study is to investigate what effect a local anesthetic nerve block of the arm in patients with end stage renal failure has upon blood flow in the skin of the arm.
- Trial name
- NCT01135979
- Where
- United Kingdom
- Sponsor
- University of Nottingham
Diaphragm; Paralysis
Neck Anatomy and Phrenic Nerve Palsy After BPB
The purpose of this study was to determine the association between the anatomical characteristics of neck and postoperative diaphragmatic paralysis in patients undergoing interscalene brachial plexus block before shoulder…
- Trial name
- NCT04783064
- Testing
- Interscalene brachial plexus block
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital