Clinical trials: Bradycardia
Hypertension Arterial, Desaturation
Dexmedetomidine During Carotid Endarterectomy: a Registry on Safety and Satisfaction of Patients and Operators (DexTEA)
From an anesthesiological perspective, carotid endarterectomy (CEA) is an operation that is increasingly being performed with locoregional techniques and sedation.
- Conditions
- Hypertension Arterial, Desaturation, Bradycardia, Surgery (Major Vascular)
- Trial name
- NCT07105527
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Saint Camillus International University of Health Sciences
Bradycardia, Heart Failure
His Bundle Pacing in Bradycardia and Heart Failure
Participants in this study will either have heart failure (HF) and are scheduled to undergo pace maker (PM) implantation, cardiac resynchronization therapy pacemaker (CRT-P), cardiac resynchronization therapy defibrillator…
- Trial name
- NCT03008291
- Testing
- CRT-D Implantation, CRT-P Implantation, Dual Chamber Pacemaker Implantation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Yong-Mei Cha
Ventricular Fibrillation, Ventricular Tachycardia
Left Ventricular Capture Management Study
Primary Objective: To characterize left ventricular (LV) threshold behavior over time using daily left ventricular capture management (LVCM) measurements.
- Conditions
- Ventricular Fibrillation, Ventricular Tachycardia, Bradyarrhythmia
- Trial name
- LEARN (NCT01089634)
- Where
- Canada
- Volunteers
- 151 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Anesthesia, Spinal, Dexmedetomidine
Atropine or Ephedrine Pretreatment for Preventing Bradycardia in Elderly Patients
Spinal anesthesia is widely used for lower extremity surgery, and sedation is often required during surgery. For sedation, propofol, midazolam and dexmedetomidine are frequently used.
- Conditions
- Anesthesia, Spinal, Dexmedetomidine, Bradycardia
- Trial name
- NCT03984526
- Testing
- normal saline, atropine 0.5mg, ephedrine 8mg
- Where
- South Korea
- Volunteers
- 102 people
- Sponsor
- Ajou University School of Medicine
Bradyarrhythmia, Dyspnea
The Safety and Efficacy of FFR Protocol in NTUH System
FFR-guided PCI has been performed in National Taiwan University Hospital(NTUH) for many years. Nevertheless, the method of FFR measurement in NTUH is different from that in literature.
- Conditions
- Bradyarrhythmia, Dyspnea, Acute Respiratory Failure
- Trial name
- NCT03693157
- Where
- Taiwan
- Volunteers
- 250 people
- Sponsor
- National Taiwan University Hospital Hsin-Chu Branch
Sinus Node Dysfunction
Registry to Improve the Adoption of Consensus Treatment Guidelines (IMPROVE Brady)
Registry to Improve the Adoption of Consensus Treatment Guidelines (IMPROVE Brady)
- Trial name
- IMPROVE Brady (NCT01643707)
- Testing
- Evidence based guidelines and tools
- Where
- 21 sites in Argentina, Bangladesh and 5 more
- Volunteers
- 1,342 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Bradycardia
A Comparison of the Pacemaker Automatic Features in Reduction of Ventricular Pacing
The COMPARE-Adapta study is a randomized, multi-center, prospective study conducted in China. The purpose of the study is to compare the ability of Search AV™+ and Managed Ventricular Pacing® (MVP®) to reduce ventricular pacing…
- Trial name
- COMPARE (NCT01039467)
- Testing
- Medtronic Adapta Dual Chamber Pacemaker
- Where
- 30 sites in China
- Volunteers
- 385 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Bradycardia, Pacing
"Physiological vs Right Ventricular Pacing Outcome Trial Evaluated for bradyCardia Treatment" (PROTECT-HF)
The PROTECT-HF multi-centre randomised controlled trial will compare two different pacing approaches for treating patients with slow heart rates.
- Conditions
- Bradycardia, Pacing, Right Ventricular Pacing, His Bundle Pacing
- Trial name
- PROTECT-HF (NCT05815745)
- Testing
- Pacemaker - Physiological pacing, Pacemaker - Right Ventricular pacing
- Where
- 45 sites in Ireland, Slovenia and 1 more
- Volunteers
- 2,600 people
- Sponsor
- Imperial College London
Bradycardia
SALT - Success of Active Versus Passive Lead Fixation of Atrial Pacing/Sensing Electrodes
Randomised Comparison with regards to complication rate and electrical measurements of atrial leads with different fixation mechnism
- Trial name
- SALT (NCT00180570)
- Testing
- FineLine II Sterox, FineLine II Sterox, FineLine II Sterox EZ
- Where
- Sweden
- Volunteers
- 385 people
- Sponsor
- Guidant Corporation
Heart Failure With a Preserved Ejection Fraction, Heart Failure, Diastolic
Efficacy Study of Pacemakers to Treat Slow Heart Rate in Patients With Heart Failure
Determine the impact of restoring normal heart rate response during exercise and daily activity in patients with heart failure and a preserved ejection fraction (HFpEF) and chronotropic incompetence (CI).
- Conditions
- Heart Failure With a Preserved Ejection Fraction, Heart Failure, Diastolic, Chronotropic Incompetence
- Trial name
- RAPID-HF (NCT02145351)
- Testing
- Rate adaptive atrial pacing using a dual-chamber pacemaker, Pacemaker system will be implanted but set to Pacing Off.
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Mayo Clinic
Bradycardia
Reduction of Right Ventricular Pacing Using the Feature Ventricular Intrinsic Preference (VIP)
The purpose of this study is to evaluate the efficacy of the VIP™ feature (available in dual chamber Victory® devices) to reduce unnecessary RV pacing, and to determine if patients with implanted SJM pacemakers will benefit by…
- Trial name
- NCT00311168
- Testing
- Intervention/treatment
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Abbott Medical Devices
Labor Pain
Prophylactic Ephedrine and Combined Spinal Epidurals for Labor
The combined spinal epidural (CSE) technique has become increasingly popular for labor pain because of its rapid onset and superior first stage analgesia.
- Trial name
- CEASE (NCT02062801)
- Testing
- Ephedrine
- Where
- United States
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- Sharp HealthCare
Hypertensive Heart Disease
The Personalized Chinese Herb Formulas Over Hypertensive Bradyarrhythmia
72 patients who have been diagnosed with hypertensive bradyarrhythmia were selected and randomly divided into research group and control group.
- Trial name
- NCT04505228
- Testing
- Safflower (Carthamus Tinctorius) IgG4 | Serum | Allergy, Atropine Sulfate
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Jun Xiao
Bradycardia
Accent MRI Pacemaker and Tendril MRI Lead New Technology Assessment
The intent of this study is to evaluate the performance of the implanted Accent MRI TM system in a clinical setting and optionally in the MRI environment. This system includes the St.
- Trial name
- NCT01258218
- Testing
- Implantation of an Accent MRI device
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Abbott Medical Devices
Bradycardia, Chronotropic Incompetence
Common Sensing and Right Ventricular Automatic Capture (COGNATE)
This study will collect data on features for future pacemakers via an external non-implantable system.
- Trial name
- COGNATE (NCT01030705)
- Where
- 5 sites in United States
- Volunteers
- 80 people
- Sponsor
- Boston Scientific Corporation
Tachycardia Atrial, Atrial Fibrillation
BIO|STREAM.ICM Obesity
The aim of the submodule study is to assess whether a high BMI may influence the sensing performance and the sECG quality of the BIOMONITOR.
- Conditions
- Tachycardia Atrial, Atrial Fibrillation, Syncope, Bradycardia
- Trial name
- NCT04198220
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Biotronik SE & Co. KG
Bradycardia, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Hyoscine Butylbromide for Prevention of Bradycardia During Cesarean Section
The aim of this study is to assess the efficacy of Iv hyoscine butylbromide in preventing Bradycardia during cesarean section under spinal anaesthesia with local anaesthetic and morphine.
- Conditions
- Bradycardia, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use, Cesarean Section Complications
- Trial name
- NCT04069078
- Testing
- Hyoscine Butylbromide 20 Mg/mL Solution for Injection Ampoule, Normal saline
- Where
- Egypt
- Volunteers
- 173 people
- Sponsor
- Assiut University
Bradycardia, Hypotension
Determination of Remifentanil's ED50 for Rapid Sequence Intubation Avoiding Bradycardia and Hypotension in Adults
This study will find the median effective dose of remifentanil for rapid sequence intubation which avoids bradycardia and hypotension
- Trial name
- NCT03065309
- Testing
- Remifentanil
- Where
- Brazil
- Volunteers
- 15 people
- Sponsor
- Brasilia University Hospital
Bradycardia
INGEVITY™ Observational Trial
The objectives of this registry are to 1. Collect clinical data on Boston Scientific's ImageReady MR Conditional Pacing Systems involving the INGEVITY lead based on observations / events 2.
- Trial name
- GENTLE (NCT02166606)
- Testing
- ImageReady MR Conditional Pacing System Implant
- Where
- 60 sites in Austria, Belgium and 11 more
- Volunteers
- 1,184 people
- Sponsor
- Boston Scientific Corporation
Apnea, Bradycardia
microEEG for Neonatal Apnea, Bradycardia and Desaturation
The study utilizes microEEG (a novel miniaturized, FDA approved EEG device) to prospectively investigate the cerebral electrical activity of infants with Apnea, Bradycardia and Desaturation events.
- Conditions
- Apnea, Bradycardia, Premature Birth, Seizures
- Trial name
- NCT02436616
- Testing
- microEEG
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Bio-Signal Group Corp.