Clinical trials: Brain, Trauma
Brain Injury, Acute
Health Outcomes for Acute Concussion
The primary purpose of this prospective observational trial is to validate the Brain Gauge device as an objective tool for concussion assessment and treatment in order to determine if a method that has proven successful in 18-22…
- Trial name
- HOAC (NCT04087434)
- Testing
- Brain Gauge Prospective and Healthy Control
- Where
- Germany
- Volunteers
- 300 people
- Sponsor
- Kendra Jorgensen-Wagers
Traumatic Brain Injury, Exercise
AI-driven Personalized Exercise Feedback Program on Exercise Adherence in Traumatic Brain Injury
This study aims to develop and evaluate an AI-driven Personalized Exercise Feedback Program (AI-PEF) to enhance exercise adherence and health outcomes in mTBI patients.
- Conditions
- Traumatic Brain Injury, Exercise, AI (Artificial Intelligence), Digital Health
- Trial name
- NCT06817564
- Testing
- AI-PEF, Theory-based digital exercise, Active Control
- Volunteers
- 125 people
- Sponsor
- National Defense Medical Center, Taiwan
Post Traumatic Stress Disorder, Traumatic Brain Injury
Therapeutic Horsemanship in Veterans
The project partnered with U.S. military veterans with a premier accredited therapeutic riding center for six weeks. The veterans interacted with horses by grooming and learning about them, as well as riding them for one hour per…
- Trial name
- NCT02891421
- Testing
- Therapeutic Horseback Riding, Standard Care
- Volunteers
- 38 people
- Sponsor
- University of Missouri-Columbia
Brain Injuries, Traumatic
Recovery Enhancement From Traumatic Brain Injury Using Acceptance and Commitment Therapy - a Pilot Study.
Is Acceptance and Commitment Therapy (ACT) feasible and acceptable for adults with severe Traumatic Brain Injury (sTBI) in inpatient services? sTBI is associated with depression, anxiety and low self awareness.
- Trial name
- REACT (NCT02337114)
- Testing
- Acceptance and Commitment Therapy, Treatment as Usual
- Where
- United Kingdom
- Volunteers
- 47 people
- Sponsor
- University of Glasgow
Perinatal Brain Injury, Healthy Participants
Sparking Potential, Revealing Infant Neurocognitive Traits
This research focuses on the long-term cognitive development of children, including healthy infants and those who had a perinatal brain injury. As part of this research study, children complete virtual game and assessments.
- Trial name
- SPRINT (NCT07390136)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Concussion, Head Injury Trauma
Detection and Prevention of Concussive Injuries With Smart Technology.
Concussions are consequences of inopportune interactions between an impact force and the head that causes the head (and brain) to move too rapidly. This project involves two parts. 1.
- Trial name
- NCT04946747
- Testing
- Modern microelectrical mechanical systems (MEMS) head-impact sensors, Virtual Reality (VR) Goggle Use with consistent timing of Conditioned Stimulus and Unconditioned Stimulus, Virtual Reality (VR) Goggle Use with inconsistent timing of Conditioned Stimulus and Unconditioned Stimulus
- Volunteers
- 100 people
- Sponsor
- Chi-Ming Huang
Craniocerebral Trauma
Fitness Training After Traumatic Brain Injury
The aim of this project is to compare the efficacy of two different fitness exercise programmes on improving fitness and psychosocial functioning in a traumatic brain injured population.
- Trial name
- NCT00251108
- Testing
- Cardiorespiratory fitness training
- Where
- 3 sites in Australia
- Volunteers
- 60 people
- Sponsor
- Sydney South West Area Health Service
Brain Injury Traumatic Mild, Post-traumatic Stress Disorder
Brain Health & Wellness Classes for Veterans With Traumatic Brain Injury
This study is testing the usefulness of two types of Brain Health \& Wellness classes for Veterans with a history of concussion to improve mental health.
- Trial name
- NCT06150196
- Testing
- Mindfulness-based Stress Reduction class, Brain Health Education class
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- East Bay Institute for Research and Education
Acquired Brain Injury, Cerebral Palsy
The Effectiveness of Robotic Gait Training in Children With Neurological Impairment
The recovery of walking ability is one of the primary rehabilitation goals for children with neurological impairment. The aim of the study is to investigate the clinical effectiveness of rehabilitation treatments based of…
- Trial name
- NCT03828110
- Testing
- Robotic Assisted Gait Training (Lokomat), Physiotherapy
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Eugenio Medea
Asphyxia Neonatorum, Neonatal Mortality
Neonatal Resuscitation in Zambia
Asphyxia is a leading cause of neonatal death in Zambia. This study will be conducted in two cities in Zambia to determine if the combined Neonatal Resuscitation Program/Essential Newborn Care Program compared to the new World…
- Conditions
- Asphyxia Neonatorum, Neonatal Mortality, Hypoxic Ischemic Encephalopathy
- Trial name
- NCT00097097
- Testing
- Neonatal Resuscitation
- Where
- Zambia
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Brain Injury Traumatic Severe, Serum Concentrations
Electrolyte Imbalance in Surgical and Non-Surgical Geriatric Brain Injury Patients
Investigators invite you to the research titled "Evaluation of Serum Electrolyte Imbalance in Geriatric Patients Undergoing Brain Surgery: A Prospective Randomized Observational Study" conducted by Specialist Nurse Tülin KURT…
- Conditions
- Brain Injury Traumatic Severe, Serum Concentrations, Nursing, Geriatric Patients
- Trial name
- NCT07809880
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Zonguldak Bulent Ecevit University
Brain Injury, Vascular, Aphasia
Treatment of Grammatical Time Marking in Post-Stroke Aphasia
The study aims to assess an individual or self-administered computer therapy's effectiveness in grammatical time marking. The main objective is to examine whether the therapy improves grammatical time marking of inflected verbs…
- Conditions
- Brain Injury, Vascular, Aphasia, Stroke
- Trial name
- NCT05656638
- Testing
- Speech and language therapy
- Where
- Switzerland
- Volunteers
- 6 people
- Sponsor
- University of Neuchatel
Severe Traumatic Brain Injury, Severe Brain Injury
The Örebro Severe Traumatic Brain Injury Registry
Traumatic brain injury and other severe brain injuries requiring neurointensive care are associated with high mortality, long-term disability and substantial societal burden.
- Conditions
- Severe Traumatic Brain Injury, Severe Brain Injury, Ischemic Stroke, Intracerebral Hemorrhage
- Trial name
- ÖrSBID (NCT07398274)
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- András Zoltán Buki
Mild Traumatic Brain Injury, Functional Neurological Disorder
Rehabilitation for Functional Memory Symptoms After Concussion
This study aims to evaluate the feasibility of novel cognitive behavioural therapy (CBT)-based intervention designed to improve functional memory symptoms after concussion.
- Trial name
- NCT05581810
- Testing
- Cognitive Behavioural Therapy (CBT), Cognitive Rehabilitation
- Where
- 10 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Kidney Injury, Pre-Term
Improving Preterm Kidney Outcomes With Caffeine
This study is being done to see if additional caffeine citrate (20 milligrams per kilogram IV bolus) helps babies with low kidney oxygenation already being treated with caffeine citrate (20 milligrams per kilogram IV bolus on day…
- Trial name
- NCT07262060
- Testing
- Caffeine citrate
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- University of Wisconsin, Madison
Brain and Central Nervous System Tumors, Cognitive/Functional Effects
Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain
RATIONALE: Donepezil may decrease the side effects caused by radiation therapy to the brain. PURPOSE: This clinical trial is studying how well donepezil works in treating young patients with primary brain tumors previously…
- Conditions
- Brain and Central Nervous System Tumors, Cognitive/Functional Effects, Long-term Effects Secondary to Cancer Therapy in Children, Neurotoxicity
- Trial name
- NCT00452868
- Testing
- Donepezil
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Wake Forest University Health Sciences
Cerebral Palsy, Acquired Brain Injury
Assessment of the Psychophysical State During Rehabilitation Treatment With Lokomat
The use of robotic technologies in rehabilitation is an increasingly widespread practice in the health sector: the Lokomat is a medical device intended for walking rehabilitation, consisting of an exoskeleton, a treadmill and a…
- Conditions
- Cerebral Palsy, Acquired Brain Injury, Hereditary Spastic Paraplegia
- Trial name
- NCT05767268
- Testing
- Lokomat
- Where
- Italy
- Volunteers
- 48 people
- Sponsor
- IRCCS Eugenio Medea
Acute Brain Injury
Multimodal Brain Monitoring as an Early Warning and Prognostic Tool for Acute Brain Injury
The primary aim of this study is to evaluate the effectiveness of multimodal brain monitoring technologies as both an early warning system and a prognostic tool in patients suffering from acute brain injuries.
- Trial name
- NCT06505213
- Testing
- no intervention
- Volunteers
- 490 people
- Sponsor
- Xiangya Hospital of Central South University
Concussion, Mild
Novel Protection Against Potential Brain, Hearing and Vision Injury During Blast Wave Exposure
The purpose of the study is to monitor changes in brain structure and function between the pre-training and post-training, in a population of tactical team members wearing the Device and compared to a similar population not…
- Trial name
- BLAST (NCT03017924)
- Testing
- Q collar
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cognitive Ability, General, Brain Injury
The Effect of Dexmedetomidine to Cognition of Geriatrics in Prolonged Surgery
The incidence of postoperative cognitive dysfunction (POCD) is high and POCD affect the life quality and the prognosis of patients.
- Trial name
- NCT02123355
- Testing
- Induction of anesthesia, Intubation, Sevoflurane, remifentanil ,vecuronium
- Volunteers
- 80 people
- Sponsor
- Shaanxi Provincial People's Hospital