Clinical trials: Brain Activity
Cerebral Hypoxia
The Effects of Hypobaria vs Hypoxia on Cerebral Functions.
The investigators will investigate the effect of hypobaria and hypoxia on physiological responses such as: oxygen saturation, heart rate, cerebral blood flow, cerebral oxygenation, brain's activity and concentration performance.
- Trial name
- Hypoxia (NCT03303118)
- Testing
- Hypoxia
- Where
- Switzerland
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Fliegerärztliches Institut
Photosensitive Epilepsy
A Study to Evaluate the Pharmacodynamic Activity of E2730 in Adult Participants With Photosensitive Epilepsy
The primary purpose of the study is to assess the pharmacodynamic (PD) activity of E2730 as measured by suppression of epileptic photoparoxysmal response (PPR) in the participant's most sensitive eye condition in participants…
- Trial name
- NCT03603639
- Testing
- E2730
- Where
- 5 sites in United States
- Volunteers
- 6 people
- Sponsor
- Eisai Inc.
Stroke
The Effectiveness of Occupation-based Bilateral Arm Training on Motor Functions and Activity Participation Among Stroke Survivors During Inpatient Rehabilitation.
People with stroke often experience limitations in motor functions and activity participation. Occupation-based bilateral upper limb training (OBBT) using occupations as meaningful daily activities, and as part of the therapy.
- Trial name
- NCT07164612
- Testing
- Occupation-Based Bilateral Upper Limb Training (OBBT), Conventional therapy group
- Where
- Qatar
- Volunteers
- 150 people
- Sponsor
- Hamad Medical Corporation
Parkinson Disease
Determinants of Physical Frailty in Parkinson's Disease: A Multi-Factorial Analysis
The aim of this study is to examine the associations between motor imagery capacity, body awareness (interoceptive awareness), kinesiophobia, physical activity level, and symptom severity in individuals with Parkinson's disease.
- Trial name
- NCT07488364
- Testing
- Observational Questionnaire and Functional Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Acibadem University
Intracerebral Hemorrhage
Improving Platelet Activity for Cerebral Hemorrhage Treatment - DDAVP Proof of Concept
The investigators intend to show that DDAVP improves platelet activity from baseline to 60 minutes after treatment start.
- Trial name
- IMPACT (NCT00961532)
- Testing
- DDAVP injection (desmopressin acetate)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Northwestern University
Stroke
Preliminary Biomechanical and Usability Study of an Active Ankle-Foot Orthesis for Stroke Survivors
This research will present the biomechanical assessment of a robotic device for ankle assistance during gait on stroke's survivors with hemiparesis. Gait pattern through an optoelectronic motion capture system will be analyzed.
- Trial name
- NCT04249349
- Testing
- Assisted gait with a motorized ankle foot orthosis
- Where
- Chile
- Volunteers
- 10 people
- Sponsor
- Corporación de Rehabilitación Club de Leones Cruz del Sur
Brain Metastasis, Radiation Therapy
18F-FLUC PET/MR in Patients With Brain Mets
The goal of this clinical trial is to use new imaging methods to help in finding out whether the imaging shows that there is a tumor in people with a brain metastasis.
- Conditions
- Brain Metastasis, Radiation Therapy, Immunotherapy, Active
- Trial name
- NCT06159335
- Testing
- F-Fluciclovine radiotracer
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Wisconsin, Madison
Healthy
Autonomic Nervous System Activity, Aging and Sleep Apnea/Hypopnea
The regulatory effects of the autonomic nervous system (ANS) concern almost all organs which permanently feed information back to this global biological vigilance system controlling allostasis.
- Trial name
- SYNAPSE (NCT00766584)
- Testing
- Sleep apnea/hypopnea detection
- Where
- France
- Volunteers
- 852 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Brain Activity, Neurodevelopmental Outcome
Analysis of Correlation of Amplitude-Integrated EEG and Neurodevelopmental Outcome in Preterm Infants
The study included analysis of longitudinal recordings of amplitude-integrated EEG (aEEG) tracings on a weekly basis in preterm infants and evaluation of their neurodevelopmental outcome at the age of three years.
- Trial name
- NCT00728234
- Testing
- aEEG recording
- Where
- Austria
- Volunteers
- 284 people
- Sponsor
- Medical University of Vienna
Healthy
Evaluation of Aging, Autonomic Nervous System Activity and Cardiovascular Events
The regulatory effects of the autonomic nervous system (ANS) concern almost all organs which permanently feed information back to this global biological vigilance system controlling allostasis.
- Trial name
- PROOF (NCT00759304)
- Where
- France
- Volunteers
- 1,011 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Gulf War Illness, Persian Gulf Syndrome
Exercise in Gulf War Illness (GWI)
The purpose of this study is to determine if submaximal exercise by bicycle stress tests with pulmonary measurement of VO2MAX plus maximal isometric hand grips on 2 consecutive days causes a higher level of "exertional…
- Trial name
- NCT01291758
- Testing
- Submaximal bicycle exercise stress tests performed 24 hr apart
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Stroke, Cerebrovascular Disorders
Effects of Exercise on Endothelial Function in Stroke Patients
This study examines the hypothesis that 6 months of treadmill aerobic exercise training improves fibrinolysis (clot defense mechanism) and vasomotor function in chronic hemiparetic (muscular weakness or partial paralysis…
- Trial name
- NCT00604877
- Testing
- Treadmill Exercise, Stretching/ROM
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- National Institute on Aging (NIA)
Obsessive-Complusive Disorder
Analysis of Visual-Motor Task Electrophysiological Activity During Deep Brain Stimulation for Treatment-Resistant Movement Disorders
Objective The objective of this pilot study is to characterize the abnormal neuronal firing patterns of basal ganglia neurons and those in the premotor cortex in patients with treatment-resistant movement disorders undergoing…
- Trial name
- NCT01485263
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Physical Activity
Comparing Effects and Neural Mechanisms of Tai Chi and Light-to-Moderate Intensity Aerobic Exercises
In this three-year project, investigators will target on sedentary middle-aged and older adults with cardiovascular risks, prescribe 24-week Tai Chi or aerobic exercises and examine: 1.
- Trial name
- NCT03275038
- Testing
- Tai-Chi exercise, Aerobic exercise
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Hemiplegia, Stroke
Impact of Physiotherapy on Spasticity, Upper Limb Function, Daily Activities, and Kinesiophobia in Hemiplegic Patients
This study investigated the effects of rehabilitation exercises on spasticity levels, upper extremity functions, activities of daily living, and kinesiophobia in patients with hemiplegia following a stroke.
- Trial name
- NCT06542848
- Testing
- Physiotherapy and Rehabilitation Practices
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- University of Beykent
Alzheimer Disease
Study Evaluating Lecozotan SR in Mild to Moderate Alzheimer's Disease (AD)
The purpose of this study is determine the safety, tolerability, and efficacy of 3 doses of lecozotan SR in patients with mild to moderate Alzheimer's Disease over 12 weeks.
- Trial name
- NCT00151398
- Testing
- lecozotan SR, Donepezil
- Where
- 56 sites in United States, Argentina and 3 more
- Volunteers
- 229 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Muscle Damage
Water Oxygenation and Brain Activity
The primary purpose of this interventional, placebo controlled, crossover, double blind, basic science exploratory study is to investigate whether there is a difference in brain electrophysiological oscillatory activity in…
- Trial name
- NCT02688452
- Testing
- Electrokinetically modified water (EMW)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Parkinson Disease
Effects of an Independent Walking Program With Walking Poles in People With Parkinson Disease
Study Purpose: The purpose of the study is to compare changes in activity levels and walking in people with Parkinson disease after an 8-week independent walking program with or without using walking poles.
- Trial name
- ActivatePD (NCT06908135)
- Testing
- Independent walking program using walking poles, Independent walking program without walking poles
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Pacific Northwest University of Health Sciences
Healthy Volunteer
A Study Assessing Brain Activity, Safety, Tolerability, and Pharmacokinetics Following Multiple Doses of MLS101 (Psilocybin) in Healthy Volunteers
MLS101 is being developed as a low dose psilocybin, that can be administered to treat neurological and psychiatric conditions. The purpose of this trial is to investigate brain activity, safety, tolerability, and PK of multiple…
- Trial name
- NCT07050368
- Testing
- Psilocybin
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- MycoMedica Life Sciences PBC
Physical Inactivity
The Effect of Brain Breaks on People With Mental Health Problems
Regular physical activity (PA) and adopting an active lifestyle protect against non-communicable diseases such as diabetes, cardiovascular diseases, hypertension, obesity, and colon cancer in the general population.
- Trial name
- NCT05783674
- Testing
- Brain Breaks® Video Exercises, Posture training
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Istinye University
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