Clinical trials: Brain Activity
Alzheimer Disease
Activity of AVE1625 in Mild to Moderate Alzheimer's Patients.
Primary: This study is being conducted to evaluate if AVE1625 is safe and tolerated in patients with Alzheimer's disease that is not too severe.
- Trial name
- NCT00380302
- Testing
- AVE1625
- Where
- 5 sites in United States, France and 3 more
- Volunteers
- 162 people
- Sponsor
- Sanofi
Cerebral Palsy, Quality of Life
Health Related Lifestyle and Quality of Life in Children With Cerebral Palsy
The primary aim of this study is assessing physical activity, the quality of sleep and health related quality of life in children with cerebral palsy, and parenting stress of caregivers of the children with cerebral palsy in…
- Conditions
- Cerebral Palsy, Quality of Life, Physical Activity, Physical Disability
- Trial name
- NCT03277027
- Testing
- interventional study
- Where
- South Korea
- Volunteers
- 62 people
- Sponsor
- The Catholic University of Korea
Stroke
Exergames on an Unstable Surface in Stroke Inpatients
Aim of this study is to assess the feasibility and effects of exergame-based cognitive-motor training on a labile platform on physical and cognitive functioning in stroke inpatients.
- Trial name
- NCT06296069
- Testing
- exergame-based cognitive-motor training on an unstable surface, exergame-based cognitive-motor training on an stable surface
- Where
- Switzerland
- Volunteers
- 29 people
- Sponsor
- Eleftheria Giannouli
Growth Hormone Disorder, Adult Growth Hormone Deficiency
A Trial Investigating the Safety, Tolerability, Availability and Distribution in the Body of Once-weekly Long-acting Growth Hormone (Somapacitan) Compared to Once Daily Norditropin NordiFlex® in Adults With Growth Hormone Deficiency
This trial is conducted in Europe. The aim of the trial is to investigate the safety, tolerability, availability and distribution in the body of once-weekly long-acting growth hormone (NNC0195-0092, somapacitan) compared to once…
- Trial name
- NCT01706783
- Testing
- somapacitan, Norditropin NordiFlex®
- Where
- 4 sites in Denmark, Sweden
- Volunteers
- 35 people
- Sponsor
- Novo Nordisk A/S
Depression
Evaluation of Use of Brain Activity Monitoring for Evaluation of Depression Treatment
This study evaluates the use of brain activity monitoring for early identification of pharmaceutical treatment efficacy and development of depression deterioration events.
- Trial name
- NCT02523105
- Testing
- EEG monitoring
- Where
- 2 sites in Israel
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Brainmarc Ltd.
Cerebral Palsy, Hemiparesis; Poststroke/CVA
Characterization of Muscle Activity During a Surface EMG-controlled Rehabilitation Game
The aim of this pilot study is to evaluate muscular activity during a single session of surface electromyography controlled exergame (muscle activation, number of contraction…) in cerebral palsy kids, hemiparetic adults and…
- Conditions
- Cerebral Palsy, Hemiparesis; Poststroke/CVA, Healthy (Controls)
- Trial name
- CONTRACTIV-1S (NCT07838688)
- Testing
- Surface electromyography (sEMG)-controlled rehabilitation game
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Cognitive Performance
Determining Which Regions of the Brain Are Active During Flight Simulation at Separate Timepoints During Training
The overall objective is to identify the cognitive circuits associated with military aviator performance by analyzing what anatomic regions of the brain are functionally "active" (neuronal circuit) while being performing virtual…
- Trial name
- fMRI Pilots (NCT06606925)
- Testing
- fMRI with virtual reality flight simulator
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- The Geneva Foundation
Stroke
SINEMA Model of Care to Improve the Health of Stroke Patients in Rural China
Despite the significant burden of stroke in rural China, secondary prevention of stroke is scarce. The aim of the study is to develop a system-integrated technology-enabled intervention (SINEMA) model for the secondary prevention…
- Trial name
- SINEMA (NCT03185858)
- Testing
- SINEMA intervention
- Where
- China
- Volunteers
- 1,299 people
- Sponsor
- Duke Kunshan University
Parkinson's Disease
Evaluating the Influence of Externally vs. Internally Focused Exercise on Rehabilitation in Parkinson's Disease
The purpose of this study is to evaluate the underlying mechanism and influence of externally vs. internally focused exercise on rehabilitation in Parkinson's disease.
- Trial name
- DT-PDSAFEx (NCT02476240)
- Testing
- Parkinson's disease Sensory Attention Focused Exercise
- Volunteers
- 65 people
- Sponsor
- Sun Life Financial Movement Disorders Research and Rehabilitation Centre
Agitation in Patients With Dementia of the Alzheimer's Type
Efficacy, Safety and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type
Participants with agitation secondary to dementia of the Alzheimer's type. The diagnosis of probable Alzheimer's disease (AD) was to be based on the "2011 Diagnostic Guidelines for Alzheimer's Disease" issued by the National…
- Trial name
- NCT02442765
- Testing
- AVP-786
- Where
- 126 sites in United States, Estonia and 4 more
- Volunteers
- 387 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Healthy Volunteers, Behavior and Behavior Mechanisms
Validation of a Making Decision Hybrid (Ecologic and Virtual) Task
The aim of this study is to validate a new hybrid (ecological + virtual) decision-making tool. The difference in behavior (risky choices) between the "hybrid" task and the "virtual" task will be evaluated.
- Trial name
- LABLife (NCT06337500)
- Testing
- Neurophysiological measure (EEG), Survey
- Where
- France
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Parkinson Disease (PD)
Behavioral Intervention for Lifestyle Physical Activity in Parkinson's Disease
The investigators propose a Stage-I randomized controlled trial (RCT) of a remotely-delivered, 16-week social-cognitive theory-based behavioral intervention focusing on combined exercise (aerobic and resistance) training for…
- Trial name
- LifePD (NCT06603012)
- Testing
- GET Up PD, Stretching and Flexibility
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Illinois Chicago
Adult Growth Hormone Deficiency
A Safety, Pharmacokinetic and Pharmacodynamic Study of ACP-001 (TransCon hGH) in Adults With Growth Hormone Deficiency
This study investigates the safety, tolerability, pharmacokinetic profile (PK), and pharmacodynamic response (PD) of three different doses of ACP-001 given once-a-week compared to one dose-level of an approved daily human growth…
- Trial name
- NCT01247675
- Testing
- ACP-001 (TransCon hGH), Omnitrope
- Where
- 4 sites in Denmark, Germany and 2 more
- Volunteers
- 37 people
- Sponsor
- Ascendis Pharma A/S
Acromegaly, Pituitary Gigantism
Efficacy and Safety of Pasireotide LAR (Long-acting Release) in Japanese Patients With Acromegaly or Pituitary Gigantism
To evaluate efficacy, safety, pharmacokinetics and pharmacodynamics of pasireotide LAR in Japanese patients with active acromegaly or pituitary gigantism.
- Trial name
- NCT01673646
- Testing
- Pasireotide LAR
- Where
- 27 sites in Japan
- Volunteers
- 33 people
- Sponsor
- Novartis Pharmaceuticals
Stroke
Effects of Group Leisure Activities and Musical Training on Hospital Stroke Rehabilitation.
The goal of this clinical trial is to learn whether adding group leisure activities and musical training can help people recover better after a stroke during their hospital rehabilitation.
- Trial name
- RehArt (NCT07541560)
- Testing
- Standard Intensive Stroke Rehabilitation Program, Music-supported Therapy, Enriched Intervention
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Escola Universitària d'Infermeria i Teràpia Ocupacional de Terrassa
Chronic Pain
Imaging Non-brain Electromagnetic Activity in Healthy Adults Using MEG
The primary purpose of this study is to determine the effectiveness of the Magnetoencephalography (MEG) instrument to record electrical activity from parts of the body other than the brain.
- Trial name
- BODMEG (NCT03232723)
- Testing
- Whole-cortex MEG System (with optional EEG)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Type 2 Diabetes Mellitus
Incretin Therapy and Exercise in Type 2 Diabetes
This study will examine changes in brain and physical health in adults with type 2 diabetes who are initiating incretin-mimetic therapy (e.g., Ozempic, Mounjaro), and determine whether adding structured exercise provides…
- Trial name
- BIOM (NCT07833813)
- Testing
- Structured Exercise Program
- Where
- Canada
- Volunteers
- 110 people
- Sponsor
- University of Regina
Unruptured Intracranial Aneurysm, Arteriovenous Cerebral Malformations
ACtive Catheterization for EndovaScular TreatmentS
The objective of this clinical investigation is to evaluate the safety and technical success of the Basecamp Vascular controllable directional GECKO guidewire when used to facilitate endovascular access to the targeted vessel in…
- Conditions
- Unruptured Intracranial Aneurysm, Arteriovenous Cerebral Malformations, Carotid Stenosis
- Trial name
- ACCESS (NCT05355259)
- Testing
- GECKO Active Guidewire
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Basecamp Vascular
Stroke
Therapeutic Effects of a New Upper Limb Robot Assisted Therapy Device for Persons After Stroke
The purpose of this pilot study is to investigate the clinical effects of a new upper limb robot assisted therapy device that is linked to a virtual therapy environment in patients with stroke.
- Trial name
- ARTHE (NCT01723046)
- Testing
- Training with new upper limb robot assisted therapy device
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Thomas More Kempen
Cryptogenic Embolic Stroke, Active Cancer
Identification the Cause of Cerebral Infarction in Patients With Cancer
Although there has been increasing interest in the association between cancer and cerebrovascular disease, the underlying pathophysiology of stroke in cancer patients is still not fully understood.
- Trial name
- NCT02212496
- Where
- South Korea
- Volunteers
- 118 people
- Sponsor
- Samsung Medical Center
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