Clinical trials: Brain Activity
Cerebral Palsy
Effects of Dual Task Training on Balance, Activity and Participation in Children With Cerebral Palsy
Cerebral palsy is a non progressive neurodevelopmental disorder that usually effects the muscles of the patients effecting its tone, strength and eventually ability to move.
- Trial name
- NCT06407765
- Testing
- Dual task training, Dual task training with backward walking
- Where
- Pakistan
- Volunteers
- 44 people
- Sponsor
- Riphah International University
Dementia, Cognitive Dysfunction
Protocolized Receptive Music Intervention to Reduce Care Refusal in Nursing Home Residents With Major Neurocognitive Disorders
The goal of this randomized study is to find out whether using a structured, protocolized music program (MUSIC CARE©) during daily hygiene care can reduce care refusal in older adults with dementia (memory and thinking…
- Conditions
- Dementia, Cognitive Dysfunction, Psychomotor Agitation, Burnout, Professional
- Trial name
- OPPOZIC' (NCT07730957)
- Testing
- Receptive music therapy, Standard Nursing Home Care
- Where
- 12 sites in France
- Volunteers
- 60 people
- Sponsor
- LNA SANTE
Stroke
Executive Functions Computerized Rehabilitation Using Virtual Reality to Improve Activities of Daily Living Post-stroke
This research aims to evaluate the effects of a cognitive reeducation carried out with the COVIRTUA Cognition software using a virtual environment, on real-life execution of activities of daily living (ADL) for patients with…
- Trial name
- RéFEx (NCT04855903)
- Testing
- Covirtua Cognition software
- Where
- 2 sites in France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Toulouse
Alzheimer Disease, Corticobasal Syndrome
Activity of Cerebral Networks, Amyloid and Microglia in Aging and Alzheimer's Disease
The temporal sequence of microglial activation, changes in functional and structural connectivity and the progression of neurocognitive deficits has not been conclusively clarified.
- Trial name
- ActiGliA (NCT06224920)
- Testing
- magnetic resonance imaging, electroencephalography, blood and CSF biomarker
- Volunteers
- 140 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Cognitive Decline, Alzheimer Disease
Effects of Real vs. Soundless Acoustic Stimulation During Deep Sleep on Brain Activity, Memory, and Blood Biomarkers in Older Adults (60-85) With Mild Memory Impairment
This study aims to explore a non-invasive way to improve memory and slow cognitive decline in older adults by enhancing sleep quality.
- Conditions
- Cognitive Decline, Alzheimer Disease, Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI)
- Trial name
- NCT06669546
- Testing
- Phase-locked auditory stimulation (PLAS)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University of Bern
Stenosis
Effects of Intense Aerobic Exercise on the Cerebrovascular Reserve Capacity in Patients With Hemodynamically Relevant Intra- and Extracranial Stenoses
The purpose of this trial is to study the improvement of cerebral hemodynamics in high risk stroke patients with impaired Cerebrovascular Reserve (CVR) due to high grade stenosis of the internal carotid (ICA) or middle cerebral…
- Trial name
- Exercise (NCT00912561)
- Testing
- Intense aerobic exercise
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Gerhard Jan Jungehuelsing
Dementia
Effects of Doll Therapy on Apathy and Activities of Daily Living Initiation Deficits in Older Adults With Dementia
Dementia is a major health challenge associated with population aging. As dementia progresses, patients often experience a decline in their ability to perform basic activities of daily living (BADL), such as dressing and personal…
- Trial name
- NCT07907042
- Testing
- Doll Therapy
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Xinyu ZHANG
Brain Injuries
Mobility and Activity Patterns in Hospitalised Severe Brain Injury
The purpose of this observational study is to quantify physical activity patterns in patients with severe acquired brain injury admitted for in-hospital rehabilitation.
- Trial name
- MAP-ABI (NCT05571462)
- Testing
- Activity monitor group
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Christian Riberholt
Huntington's Disease
Feasibility and Acceptability of Implementing a Clinic-based Physical Activity Coaching Intervention in People With Premanifest and Early Stage HD
This study will evaluate the feasibility and acceptability of a clinic-based physical activity coaching intervention in people with pre-manifest and early stage Huntington's Disease (HD).
- Trial name
- NCT03306888
- Testing
- Physical Activity Coaching
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Teachers College, Columbia University
Magnetic Resonance Imaging, Neuronal Activity
Perception of Baby's Painful Cry in fMRI
Crying is the primary signaling strategy available to the human newborn for eliciting parental care. Yet, the investigators only have superficial understanding of the information carried by cries, and how this information is…
- Trial name
- NCT03190486
- Testing
- functional Magnetic Resonance Imaging (fMRI)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Stroke, Cerebral Palsy
Usability Testing of a Bilateral Activities of Daily Exercise Robot for Stroke Therapy
In stroke rehabilitation, unilateral training of the impaired limb after stroke is often the frequent strategy used over bilateral ones.
- Trial name
- BiADLER (NCT02882646)
- Testing
- Bi-ADLER
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Schizophrenia
Lurasidone Vs Olanzapine on Neurotrophic Biomarkers and Cardiometabolic Parameters in Unmedicated Schizophrenia
Schizophrenia (SCZ) is a chronic, severe and disabling mental disorder with unclear etiology and pathophysiology concerned with neuro-developmental,neurodegenerative abnormalities and cognitive impairmentslinked to behavioural…
- Trial name
- NCT03304457
- Testing
- Olanzapine, Lurasidone
- Where
- India
- Volunteers
- 100 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Stroke, Neglect, Hemispatial
Motor Imaging, Neglect, and Upper Extremity Function in Stroke
This study aims to investigate the relationship between motor imagery skills and neglect level, upper extremity motor function, activities of daily living, quality of life, lateralization performance, and mental timer performance…
- Conditions
- Stroke, Neglect, Hemispatial, Motor ımargery, Upper Extremity Function
- Trial name
- NCT07480122
- Testing
- No intervention will be made; an assessment will be conducted.
- Volunteers
- 50 people
- Sponsor
- Inonu University
Limited Stage Small Cell Lung Cancer, Extensive-stage Small-cell Lung Cancer
PRophylactic Cerebral Irradiation or Active MAgnetic Resonance Imaging Surveillance in Small-cell Lung Cancer Patients (PRIMALung Study)
In this phase III study, the primary objective is to test with a one-sided significance of 5% whether for the treatment of small cell lung cancer (SCLC) patients, brain MRI surveillance alone is non-inferior in terms of overall…
- Trial name
- PRIMALung (NCT04790253)
- Testing
- Prophylactic cranial irradiation
- Where
- 55 sites in Austria, Belgium and 7 more
- Volunteers
- 600 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Antenatal Depression, Major Depressive Disorder
Pilot Study of Personalized Aperiodic Transcranial Alternating Current Stimulation in Antenatal Depression (PandA-tACS)
The purpose of this study is to develop the safety, feasibility, and tolerability of a personalized transcranial alternating current stimulation (tACS) approach in antenatal depression.
- Conditions
- Antenatal Depression, Major Depressive Disorder, Major Depressive Disorder in Pregnancy, Healthy Controls
- Trial name
- PandA-tACS (NCT06979154)
- Testing
- tACS (aperiodic)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Parkinson's Disease, Multiple Sclerosis
Blood Lactate Concentrations With and Without Exercise in Parkinson's Disease and Multiple Sclerosis Patients
Fatigue is one of the most common and debilitating symptoms experienced in Parkinson's Disease (PD) and Multiple Sclerosis (MS).
- Trial name
- PDMSLac (NCT02184494)
- Testing
- pro5 AIRdaptive Power Plate (Badhoevedorp, The Netherlands)
- Where
- 2 sites in United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Florida State University
Alzheimer's Disease
Clinical- and Immunological Activity, Safety and Tolerability of Different Doses / Formulations of AFFITOPE AD02 in Early Alzheimer's Disease
This is a multiple vaccination study to find out if it is a safe treatment and what effects it has on the symptoms of early Alzheimer's disease in male and female patients aged 50 to 80 years.
- Trial name
- NCT01117818
- Testing
- active: AFFITOPE AD02
- Where
- 31 sites in Austria, Croatia and 4 more
- Volunteers
- 335 people
- Sponsor
- Affiris AG
Stroke, Post-stroke Depression
Physical Capacity Building for Chronic Stroke
Cardiac rehabilitation is the standard-of-care treatment option for patients with cardiovascular disease and has been shown to improve many aspects critical to patient recovery.
- Trial name
- NCT07039305
- Testing
- Physical capacity training for chronic stroke - building aerobic capacity and muscle strength
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Medical University of South Carolina
Posttraumatic Stress Disorder
Exploring Mechanisms of Action in MDMA-assisted Psychotherapy for PTSD
The goal of this observational sub-study is to provide information on how MDMA-assisted therapy affects the brain and body of people with chronic PTSD.
- Trial name
- NCT02102802
- Testing
- Midomafetamine, Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Resilient Pharmaceuticals
Fibromyalgia, Healthy Volunteers
Explosive Synchronization of Brain Network Activity in Chronic Pain
This project is being conducted to evaluate the impact of explosive synchronization (ES) and its treatment with non-invasive brain stimulation in fibromyalgia (FM).
- Trial name
- NCT04606095
- Testing
- EEG, Neuroimaging EEG/fMRI (Aim 1), HD-tDCS treatments
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Michigan
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