Clinical trials: Brain Activity
Parkinson Disease
Efficacy and Tolerability of Nebicapone in Parkinson's Disease Patients With "Wearingoff" Phenomenon
The purpose of this study was to investigate the effect on the "wearing-off" phenomenon of 3 different doses of nebicapone (NEB 50 mg, 100 mg and 150 mg), compared with entacapone and placebo when dministered concomitantly with…
- Trial name
- NCT03103399
- Testing
- Comtan®, Nebicapone, Levodopa/DDCI
- Volunteers
- 254 people
- Sponsor
- Bial - Portela C S.A.
Attention Deficit Hyperactivity Disorder (ADHD)
Train Your Brain and Exercise Your Heart? Advancing the Treatment for Attention Deficit Hyperactivity Disorder (ADHD)
Attention Deficit Hyperactivity Disorder (ADHD) is a developmental disorder that has a severe impact on a child's life and society. The core symptoms are attention problems, hyperactivity and impulsivity.
- Trial name
- NCT01363544
- Testing
- Neurofeedback, Exercise, methylphenidate
- Where
- 6 sites in Netherlands
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- R. van Mourik
Migraine in Adults
EXErcise in MIGraine
The study project aims to implement therapeutic patient education for migraine, promoting improvement in outpatient clinical practice by providing counseling moments specifically dedicated to known health risk factors (sedentary…
- Trial name
- EXEMIG/01 (NCT07508449)
- Testing
- exercise program supervised by specialized kinesiologists, Standard neurological visit at the Headache Centre
- Where
- 2 sites in Italy
- Volunteers
- 140 people
- Sponsor
- Centro Universitario Ricerca Interdipartimentale Attivita' Motoria
Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy
Effects of High-Velocity Passive Stretch on Spasticity, Function, and Muscle Structure in Spastic CP Children
One of the traditional exercises applied to cerebral palsy (CP) is passive stretching exercises. Passive stretching exercises can be applied to these patients at various speeds.
- Conditions
- Cerebral Palsy (CP), Spastic Diplegia Cerebral Palsy, Spastic Hemiplegic Cerebral Palsy
- Trial name
- NCT07007858
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Stress, Anxiety
Stress Management Program
This study will test the immediate and long term (post 4 weeks of daily practice) effectiveness of two breathwork practices, cyclic sighing and box breathing, in comparison to hypnosis and an audiobook about stress, on…
- Trial name
- NCT06526585
- Testing
- Cyclic Sighing Breathing, Box Breathing, Hypnosis
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Stanford University
Movement Disorders, Parkinson Disease
A Smartphone Based, Titrated Exercise Solution for Patients With Parkinson's Disease in Daily Life: Pilot Study
The aim of this pilot randomized controlled trial is to test whether it's feasible to increase participants' step counts within four weeks with a developed motivational smartphone application.
- Trial name
- STEPWISE (NCT06692387)
- Testing
- Step count increase with the use of a motivational application
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
Chronic Musculoskeletal Pain, Tennis Elbow
A Neurofeedback Treatment for Chronic Musculoskeletal Pain
This study evaluates the effects of a novel neurofeedback treatment on pain specific brainwaves in adults. Chronic pain patients enrolled in this study will be randomized into a treatment group and a sham group.
- Conditions
- Chronic Musculoskeletal Pain, Tennis Elbow, Musculoskeletal Pain, Lateral Epicondylitis
- Trial name
- NCT03863847
- Testing
- Neurofeedback
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- Aalborg University
"Attention Deficit Hyperactivity Disorder"
Identifying Characteristic Signature of Attention Deficit / Hyperactivity Disorder (ADHD) and Ritalin Treatment
In this study we try to identify the signature of brain activity in the EEG of attention deficit disorder (ADHD) patients compared to healthy subjects under different doses of Ritalin (methylphenidate) treatment.
- Trial name
- NCT01962181
- Testing
- Ritalin
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Acromegaly
Study to Predict Lanreotide-induced Disease Activity Normalization in Acromegaly
The purpose of the study is to collect data about predictive factors for the efficacy of Lanreotide Autogel in patients with acromegaly in routine clinical practice.
- Trial name
- PLAN-A (NCT04003519)
- Sponsor
- Ipsen
Spinal Cord Injuries, Multiple Sclerosis
Validity and Reliability of Turkish Version Leg Activity Measure
Patient-filled scales minimize the burden of data collection for clinicians in a clinical setting. Therefore, Leg activity measure, a new self-report measure of active and passive function in the leg, has been developed.
- Conditions
- Spinal Cord Injuries, Multiple Sclerosis, Stroke
- Trial name
- NCT05182411
- Testing
- assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Parkinson Disease, Exercise
Effects of a High-intensity Progressive-cycle Program on Quality of Life and Motor Symptomatology in Parkinson's Disease
TITLE: Effects of a high-intensity progressive-cycle program on quality of life and motor symptomatology in Parkinson's disease population BACKGROUND: The benefits of aerobic exercise in persons with Parkinson's disease (PD) have…
- Conditions
- Parkinson Disease, Exercise, Physical Activity, Quality of Life
- Trial name
- NCT03882398
- Testing
- Balance, Endurance
- Where
- Spain
- Volunteers
- 14 people
- Sponsor
- University of Vigo
Healthy
Autonomic Nervous System Activity, Aging and Sleep Apnea/Hypopnea
The regulatory effects of the autonomic nervous system (ANS) concern almost all organs which permanently feed information back to this global biological vigilance system controlling allostasis.
- Trial name
- SYNAPSE (NCT00766584)
- Testing
- Sleep apnea/hypopnea detection
- Where
- France
- Volunteers
- 852 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Concussion, Sport-Related Concussion
Trial Study of an Exercise Program for Youth With Persistent Symptoms After Concussion
The purpose of this randomized control trial study is to determine if an active rehabilitation (low intensity exercise program) in combination with a comprehensive education intervention (standard care) is more effective than the…
- Conditions
- Concussion, Sport-Related Concussion, Mild Traumatic Brain Injury
- Trial name
- NCT02257749
- Testing
- Active Rehabilitation, Comprehensive Education Intervention (Standard Care)
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Sedentary Lifestyle
Effects of a Bicycling Intervention on Cognitive Skills and Cardiovascular Health
Although exercise is known to delay cognitive decline and decrease our risk of Alzheimer's Disease, there is a lack of understanding of how exercise protects the aging brain.
- Trial name
- BIKE (NCT02453178)
- Testing
- Cycling
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Alcohol Craving
Quantitative EEG Assessment of Cue-Induced Changes in Brain Activity in Alcohol Use Disorders
Exposure to alcohol related cues, such as the sight of alcoholic drinks, may induce craving for alcohol in drinkers. In this study, the effects of exposure to (1) the pictures of alcoholic drinks and (2) the imagining of a scene…
- Trial name
- NCT01507909
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Boston University
Specific Language Impairment
Specific Language Impairment (SLI) in Children May Caused by Epileptic Brain Activity
The objective of this study was to find if there is a possible association and the impact of epilepsy and epileptiform activity in children with SLI.
- Trial name
- NCT04141332
- Testing
- EEG was recorded by EEG Machines
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Mansoura University Hospital
Epilepsy
Investigation of Human Epileptic Networks by fMRI
Background: In the Emilia-Romagna Region approximately 19.000 people are affected by epilepsy. About 25% of epileptic patients are drug-resistant (DRE) and some of them are eligible for resective surgery of the epileptogenic zone…
- Trial name
- NCT03582345
- Testing
- EEG/fMRI
- Volunteers
- 35 people
- Sponsor
- Azienda Unita' Sanitaria Locale Di Modena
Hyperphagia
Effects of Noninvasive Brain Stimulation on Brain Activity and Appetite
The goal of this project is to identify brain mechanisms by which Noninvasive brain stimulation (NIBS) could decrease hyperphagia.
- Trial name
- NCT02758262
- Testing
- Noninvasive brain stimulation
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Laval University
Parkinson's Disease
Carbidopa/Levodopa/Entacapone Versus Immediate Release (IR) Carbidopa/Levodopa on Non-motor Symptoms in Patients With Idiopathic Parkinson's Disease and Demonstrating Non-motor Symptoms of Wearing Off
The purpose of this study is to test the effects of carbidopa/levodopa/entacapone compared to the effects of immediate-release carbidopa/levodopa on non-motor symptoms of end-of-dose wearing off in persons who have Parkinson's…
- Trial name
- NCT00642356
- Testing
- Carbidopa/levodopa/entacapone, Immediate release carbidopa/levodopa
- Where
- 21 sites in United States
- Volunteers
- 14 people
- Sponsor
- Novartis
Hemiplegic Cerebral Palsy, Cerebral Palsy (CP)
Effects of Fun-Core (Child-Friendly Core Stabilization) Exercises on Balance and Functional Mobility in Children With Spastic Cerebral Palsy
A total of 54 children, aged between 6 and 12 years, diagnosed with hemiplegic cerebral palsy and not meeting the exclusion criteria, who registered at the outpatient clinics of the Department of Physical Medicine and…
- Conditions
- Hemiplegic Cerebral Palsy, Cerebral Palsy (CP), Core Stabilization, Exercise
- Trial name
- NCT07233824
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Istanbul University
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