Clinical trials: Brain Activity
Magnetic Resonance Imaging, Neuronal Activity
Cracking the Code of Crying Babies: How Familiarity Changes the Interpretation of Cries
Understanding babies' signals is essential to meet their needs. Recent works suggest that crying provides useful information, not only allowing parents to recognize their baby among others (static information), but also to…
- Trial name
- BEBEDOL (NCT05170178)
- Testing
- inclusion and familiarization, fMRI acquisition and closure
- Where
- 2 sites in France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Stroke
Real World Upper Extremity Activity of Stroke Survivors
The investigators want to objectively measure, through the use of accelerometers, the time, movement intensity, and bilaterality of Upper Extremity (UE) activity and see if these improve over the course of therapy.
- Trial name
- NCT07557940
- Volunteers
- 15 people
- Sponsor
- Shirley Ryan AbilityLab
Alzheimer's Disease, Late Onset
Effects of Aerobic Exercise for Treating Alzheimer's Disease
This randomized controlled trial (RCT) will investigate the effects of a 6-month, individualized, moderate-intensity cycling intervention on cognition and hippocampal volume in AD with three aims: Determine the immediate effect…
- Trial name
- FIT-AD (NCT01954550)
- Testing
- Cycling exercise, Range of motion/stretching exercise
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Minnesota
Pituitary Adenoma, Prolactinoma
Comparison of Treatment Outcome of Cabergoline According to Target Prolactin Levels in Patients With Prolactinoma
The aim of this study is to investigate whether inhibition of serum prolactin levels below normal range during cabergoline administration may reduce the recurrence rate after drug withdrawal in patients with prolactinomas.
- Conditions
- Pituitary Adenoma, Prolactinoma, Pituitary Tumor, Recurrence Tumor
- Trial name
- NCT03457389
- Testing
- Cabergoline
- Where
- South Korea
- Volunteers
- 68 people
- Sponsor
- Seoul National University Hospital
Upper Extremity Hemiplegia, Stroke
Virtual Reality-Based Upper Limb Rehabilitation in Hemiplegia
This study aims to evaluate the effectiveness of Leap Motion-supported virtual reality therapy, applied in addition to traditional rehabilitation programs, in individuals who develop hemiplegia after a cerebrovascular accident.
- Conditions
- Upper Extremity Hemiplegia, Stroke, Virtual Reality Based Therapy
- Trial name
- NCT07378085
- Testing
- conventional rehabilitation, leap motion based virtual reality rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Parkinson Disease, Cognition Disorder
The Role of EEG in Identifying Cognitive Changes in Parkinson's Disease
This study is a group controlled clinical trial. Parallel study, patients aged 40-80 years, with Parkinson disease. Twelve sessions, three times a week, for 30 minutes.
- Conditions
- Parkinson Disease, Cognition Disorder, EEG With Abnormally Slow Frequencies
- Trial name
- NCT06145776
- Testing
- tDCS + tredmill training (Standart trehab training), Cognitite-motor Dual Task Training (DT training)
- Where
- 2 sites in Brazil
- Volunteers
- 36 people
- Sponsor
- Federal University of Paraíba
Dementia
Virtual Reality Training to Support Daily Activities for People Living With Dementia
This study will test whether a home-based virtual reality training program can help people living with dementia practice everyday activities.
- Trial name
- NCT07829913
- Testing
- At-Home VR-Based IADL Training, Cognitive Stimulation Activities
- Volunteers
- 40 people
- Sponsor
- Indiana University
Parkinson's Disease
Feasibility and Acceptability of a Physical Activity Behavior Change Intervention for Parkinson's Disease
The purpose of this study is to assess the feasibility, in regards to acceptability and implementation, of the Pre-Active PD intervention for increased high intensity goal-directed aerobic exercise engagement in people with…
- Trial name
- Preactive-PD (NCT03696589)
- Testing
- Physical Activity Coaching
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Teachers College, Columbia University
Alzheimer Disease, Anxiety
Cannabidiol Solution for the Treatment of Behavioral Symptoms in Older Adults With Mild Cognitive Impairment or Alzheimer's Dementia
This is an open label, eight week, clinical trial of a proprietary high CBD/low THC sublingual solution for the treatment of clinically significant anxiety and agitation in individuals with mild cognitive impairment (MCI) or mild…
- Conditions
- Alzheimer Disease, Anxiety, Agitation,Psychomotor, Mild Cognitive Impairment (MCI) Due to Alzheimer's Disease
- Trial name
- CBD (NCT04075435)
- Testing
- high CBD/low THC sublingual solution
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mclean Hospital
Vertigo, Vertigo, Peripheral
Effectiveness of Gaze Stability Exercises on Balance and Activities of Daily Living Among Patients Suffering Vertigo With Vestibular Neuritis in Saudi Arabia
Gaze stability exercise is a medical procedure for persons with unilateral vestibular disturbances such as vestibular neuritis or persons who have had tumors of their 8th nerve.
- Conditions
- Vertigo, Vertigo, Peripheral, Vertigo Labyrinthine, Migraine
- Trial name
- NCT04842474
- Testing
- Gaze stability exercises and balance exercises
- Where
- Saudi Arabia
- Volunteers
- 20 people
- Sponsor
- King Saud University
Melanoma (Skin)
Phase II Study of Nivolumab in Combination With Relatlimab in Patients With Active Melanoma Brain Metastases
To learn if giving nivolumab in combination with relatlimab can help to control melanoma that has spread to the brain (melanoma with brain metastases).
- Trial name
- NCT05704647
- Testing
- BMS-986213 (Relatlimab-Nivolumab FDC), Nivolumab, Relatlimab
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Spastic Cerebral Palsy, Motor Activity
Investigation of the Relationship Between Lower and Upper Extremity Selective Motor Control and Sensory Functions in Children With Spastic Cerebral Palsy
Although spasticity, contractures and muscle weakness in children with CP are disorders that can be observed more easily and are more focused and given more importance in evaluation and treatment approaches; Inadequate or loss of…
- Conditions
- Spastic Cerebral Palsy, Motor Activity, Lower Extremity Problem, Upper Extremity Problem
- Trial name
- NCT05696535
- Volunteers
- 100 people
- Sponsor
- Mustafa Kemal University
Alzheimer Disease
Influence of Physical Exercise as Adjuvant Treatment in Patients With Alzheimer's Disease
The goal of this non-randomized clinical trial is to assess the effects of strength training in the physical function of Alzheimer's disease (AD) patients. The main question it aims to answer are: 1.
- Trial name
- NCT05862935
- Testing
- Supervised Physical Activity (AMRAP -As Many Repetitions As Possible): Phase 2, Supervised Physical Activity: Phase 1
- Where
- Spain
- Volunteers
- 26 people
- Sponsor
- European University Miguel de Cervantes
Cervicogenic Headache
Trigger Point Therapy in Cervicogenic Headache
It is a pilot randomized controlled trial comparing real and simulated manual treatment of trigger points (TrPs) in patients with cervicogenic headache (CeH).
- Trial name
- NCT01790074
- Testing
- TrP therapy, TrP manual control therapy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- César Fernández-de-las-Peñas
Neurodegenerative Diseases, Behavioral Symptoms
Impact of Harp Therapy on Behavioral Disorders in Nursing Home Residents With Neurodegenerative Disease (ARPE)
The ARPE study looked at whether weekly harp therapy sessions could reduce behavioral problems in older adults living in memory care units of a nursing home (EHPAD).
- Conditions
- Neurodegenerative Diseases, Behavioral Symptoms, Dementia, Agitation
- Trial name
- ARPE (NCT07748013)
- Testing
- Harp therapy (receptive music therapy)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- LNA SANTE
Stroke, Cerebral Infarction
Enhancing Physical Therapy Best Practice for Improving Walking After Stroke
The aim of this study is to assess the effect of implementing best practices into current stroke rehabilitation physical therapy on walking outcomes.
- Conditions
- Stroke, Cerebral Infarction, Brain Ischemia, Infarction, Brain
- Trial name
- NCT04238260
- Testing
- Enhancing Physical Therapy Usual Care, Physical Therapy Usual Care
- Where
- Canada
- Volunteers
- 306 people
- Sponsor
- University of British Columbia
Stroke
Neurofeedback for Stroke Rehabilitation
Real-time neurofeedback aims to alter brain activation patterns through online feedback of ongoing brain activity using magnetic resonance imagining (MRI).
- Trial name
- NCT03775915
- Testing
- Neurofeedback
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- University of Oxford
Dynamic Balance, Postural Balance
The Effects of Brain Breaks on Dynamic Balance in University Students
The goal of this study is to learn if an online physical activity program called "Brain Breaks" can improve well-being among university students.
- Trial name
- NCT07546747
- Testing
- Brain Breaks Intervention
- Where
- China
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Anhui Medical University
Diabetes, Effects of Liraglutide Administration on Brain Activity
Liraglutide in Obesity and Diabetes: Identification of CNS Targets Using fMRI
The main purpose of this study is to help us understand the effects of diabetes medication Liraglutide on weight loss and hunger.
- Conditions
- Diabetes, Effects of Liraglutide Administration on Brain Activity, Weight Loss, Hunger
- Trial name
- NCT01562678
- Testing
- Liraglutide
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Beth Israel Deaconess Medical Center
Mild Cognitive Impairment (MCI), AMCI - Amnestic Mild Cognitive Impairment
Effects of Combined Aerobic and Cognitive Training in a Simultaneous or Sequential Paradigm on Cognition and Brain Functional Activity in Patients with AMCI
Mild Cognitive Impairment (MCI) is a condition in which patients show an objective evidence of impairment in one or more cognitive domains but a spared independence in daily functional abilities.
- Conditions
- Mild Cognitive Impairment (MCI), AMCI - Amnestic Mild Cognitive Impairment, Neurodegenerative Dementia, Neurodegenerative Disease
- Trial name
- NCT06755164
- Testing
- Simultaneous aerobic and cognitive training (SIM), Sequential aerobic and cognitive training (SEQ)
- Where
- Italy
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
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