Clinical trials: Brain Activity
Cerebral Palsy, Physical Activity
Effects of Hippotherapy on Physical Fitness and Attention in Cerebral Palsy
This research analyzes whether hippotherapy improves the physical activity, cardiopulmonary fitness, and attention in children with cerebral palsy and whether this enhances their general health and quality of life.
- Conditions
- Cerebral Palsy, Physical Activity, Attention Disorder
- Trial name
- NCT03870893
- Testing
- hippotherapy
- Where
- South Korea
- Volunteers
- 47 people
- Sponsor
- Samsung Medical Center
Acromegaly
Efficacy and Tolerability of Lanreotide (Autogel 120 mg) in Patients With Acromegaly
The purpose of the protocol, is to evaluate if lanreotide Autogel 120 mg is effective in the control of Growth Hormone (GH) secretion in patients with active acromegaly.
- Trial name
- NCT00499993
- Testing
- lanreotide (Autogel formulation), duration of treatment 46-48 weeks
- Where
- 24 sites in Italy
- Volunteers
- 63 people
- Sponsor
- Ipsen
Alzheimer Disease
Safety and Tolerability of Repeated Subcutaneous Injections of CAD106 in Mild Alzheimer's Patients.
This study will evaluate the safety and tolerability of repeated subcutaneous injections of CAD106 in patients with mild Alzheimer's disease.
- Trial name
- NCT00733863
- Testing
- CAD106
- Where
- 4 sites in France, Sweden and 2 more
- Volunteers
- 27 people
- Sponsor
- Novartis
Exposure to Man-made Visible Light
Systematically Assessing Effects of Colored Light on Humans With a Multi-modal Approach (Substudy 6 of 7)
NOTE: This is the sixth of in total 7 sub-studies related to the Ethics Committee of the Canton of Bern Ref. No. KEK-BE 2016-00674.
- Trial name
- NCT02919163
- Testing
- Visible light exposure
- Where
- Switzerland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Bern
COPD - Chronic Obstructive Pulmonary Disease, Healty Controls
Hemodynamic Responses and Brain Activity During Dual Tasks in COPD Patients Versus Healthy Individuals
Abstract Cognitive dysfunction is joint in patients with chronic obstructive pulmonary disease (COPD). In particular, there are effects in tasks that require attention, executive functions, and working memory related to the…
- Trial name
- NCT06974448
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Parkinson Disease
Telerehabilitation for Dysautonomia in Parkinson's Disease
People diagnosed with Parkinson's Disease (PD) exhibit a combination of motor and non-motor symptoms, with the latter posing challenges in terms of identification and management.
- Trial name
- PKT (NCT06017232)
- Testing
- Hybrid telerehabilitation program
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Université de Sherbrooke
Healthy, Nonneurogenic Neurogenic Bladder Dysfunction
Study of Electroencephalogram (EEG) Measurement During Different Stimulations of the Lower Urinary Tract
The purpose of this study is to investigate afferent and cortical activities during bladder filling under different stimulations of the lower urinary tract.
- Conditions
- Healthy, Nonneurogenic Neurogenic Bladder Dysfunction, Neurogenic Bladder Dysfunction Nos
- Trial name
- NCT01389921
- Testing
- Electroencephalography
- Where
- Switzerland
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Ulrich Mehnert
Ischemic Stroke, Transient Ischemic Attack
Efficacy of Ticagrelor Plus Aspirin in Mild Non-cardioembolic Ischemic Stroke
This is a randomized, controlled, active comparator arm, outcome assessor blind, parallel group design on 90 patient with diagnosis of ischemic stroke admitted in Bou-Ali Sina Hospital, Sari,Iran.The aim of study is assess the…
- Trial name
- TACAMINIS (NCT04738097)
- Testing
- Ticagrelor 90mg, Clopidogrel 75 mg
- Where
- 2 sites in Iran
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mazandaran University of Medical Sciences
Pediatric Brain Tumor, Cognitive Impairment
Fitness to Aid the Brain and Cognitive Skills
The study will assess the feasibility of a pilot clinical trial of community-led aerobic exercise training for paediatric brain tumour survivors (PBTS) and the feasibility of a web-based platform to deliver this exercise…
- Trial name
- Fit ABCS (NCT05367076)
- Testing
- Web-based Aerobic Exercise Program
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- The Hospital for Sick Children
Alzheimer's Disease, Psychosis
Treatment of Behavioral Symptoms in Alzheimer's Disease
The optimal strategy for the treatment of behavioral complications in patients with probable Alzheimer's disease (AD) remains unclear.
- Conditions
- Alzheimer's Disease, Psychosis, Agitation
- Trial name
- NCT00009217
- Testing
- Haloperidol-Haloperidol
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- New York State Psychiatric Institute
Dementia
Telemonitoring of Activities of Daily Living in Home Care Services of Older Adults With Cognitive Deficits
In Canada, it is estimated that two million people are users of publicly funded home care services, with more than half of them being 65 years and older.
- Trial name
- NCT06888713
- Testing
- Telemonitoring of ADL
- Where
- 3 sites in Canada
- Volunteers
- 200 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Stroke with Hemiparesis, Stroke
Impact of the BOOST GAIT Program on Gait Recovery and Functional Mobility After Stroke
The overarching goal is to determine if the BOOST GAIT program can improve functional mobility in patients with stroke who are undergoing inpatient rehabilitation and have some walking function, through the application of…
- Trial name
- BOOST GAIT (NCT06612359)
- Testing
- BOOST GAIT Program
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- Hasselt University
Migraine Disorders, Heart Disease
Telcagepant (MK-0974) Treatment of Migraine in Participants With Stable Vascular Disease (MK-0974-034)
The purpose of this study is to evaluate the safety and efficacy of telcagepant in the treatment of acute migraine in participants with stable vascular disease.
- Conditions
- Migraine Disorders, Heart Disease, Cerebrovascular Accident, TIA (Transient Ischemic Attack)
- Trial name
- NCT00662818
- Testing
- Telcagepant, Acetaminophen/Paracetamol
- Volunteers
- 165 people
- Sponsor
- Merck Sharp & Dohme LLC
Alzheimer Dementia, Agitation,Psychomotor
Electroconvulsive Therapy (ECT) for Agitation in Dementia (AD)
This study will explore the effect of ECT treatments plus usual care (ECT+UC) in reducing severe agitation in patients with moderate to severe dementia including Alzheimer's Disease, Vascular dementia, Frontotemporal dementia…
- Trial name
- ECT-AD (NCT03926520)
- Testing
- Electroconvulsive Therapy (ECT)
- Where
- 5 sites in United States
- Volunteers
- 41 people
- Sponsor
- Brent Forester
Stroke
Exercise Training and Walking Ability After Chronic Stroke
This study will investigate the efficacy of aerobic exercise and progressive resistance training (PRT), singularly and combined, on changes in walking endurance for mildly-to-moderately affected chronic stroke patients.
- Trial name
- NCT00107068
- Testing
- [A] Aerobic isokinetic cycling exercise, [B] Progressive Resistance Training, [A] + [B]
- Where
- Australia
- Volunteers
- 48 people
- Sponsor
- University of Sydney
Stroke, Upper Extremity Spasticity
Kinesiotaping Combined With Therapeutic Exercise in Upper Extremity Spasticity and Function in Subacute Stroke Patients
Poststroke spasticity (PSS) is one of the common complications in stroke patients who had a brain injury leading to limbs weakness and impaired coordination between agonist and antagonist contraction.
- Trial name
- NCT03024190
- Testing
- Kinesiotaping, stretching exercise, OT rehabilitation program
- Volunteers
- 36 people
- Sponsor
- Chang Gung Memorial Hospital
Parkinson Disease
PD-Ballet: Effectiveness and Implementation in Parkinson's Disease
Current literature consistently demonstrates beneficial motor effects of dance-based therapies in Parkinson's disease, along with improved quality of life. Little is known about the non-motor gains following such therapy.
- Trial name
- NCT04719468
- Testing
- Dance with ballet elements
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- King's College Hospital NHS Trust
Fabry Disease
Study of the Safety and Efficacy of PRX-102 Compared to Agalsidase Beta on Renal Function
This was a randomized, double-blind, active control study of the enzyme replacement therapy (ERT) drug PRX-102 (pegunigalsidase alfa) in Fabry disease patients with impaired renal function.
- Trial name
- BALANCE (NCT02795676)
- Testing
- PRX-102 (pegunigalsidase alfa), agalsidase beta
- Where
- 29 sites in United States, Czechia and 10 more
- Volunteers
- 78 people
- Sponsor
- Protalix
Alzheimer's Disease
Effects of Group Music Therapy Interventions on Alzheimer's Disease Patients: a Three-arm Randomized Controlled Blind Study.
The purpose of this study is to determine what type of music therapy (active versus passive) approach has higher effects on clinical symptoms in advanced Alzheimer's disease patients
- Trial name
- NCT04761497
- Testing
- Actice music therapy, Watching nature videos, Passive music therapy
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universidad Católica San Antonio de Murcia
Stroke, Exercise
The Influence of Exercise on Neuroplasticity and Motor Learning After Stroke
Participants will complete 11 sessions. These include screening, 5 sessions where exercise or rest (according to group assignment) are paired with practice of a motor task, MRI and Transcranial Magnetic Stimulation (TMS) before…
- Conditions
- Stroke, Exercise, Rest
- Trial name
- EX-ML3 (NCT02980796)
- Testing
- Exercise, Practice
- Where
- Canada
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- University of British Columbia