Clinical trials: Brain Activity
Cerebral Palsy (CP), Telerehabilitation
Effectiveness of Wearable Trackers and Telerehabilitation in Cerebral Palsy
The inadequate number of rehabilitation sessions and the difficulties in accessing rehabilitation services for people with cerebral palsy result in delayed progress and low levels of physical activity for these people.
- Conditions
- Cerebral Palsy (CP), Telerehabilitation, Physical Activity
- Trial name
- NCT06800014
- Testing
- Telerehabilitation, Conventional exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kutahya Health Sciences University
Vascular Cognitive Impairment
Impact of Physical Activity in Vascular Cognitive Impairment ( AFIVASC )
Vascular cognitive impairment (VCI) is one of the most frequent causes of cognitive impairment associated with aging. So far, there is no approved treatment for VCI.
- Trial name
- AFIVASC (NCT03578614)
- Testing
- Physical Activity
- Where
- Portugal
- Volunteers
- 104 people
- Sponsor
- Instituto de Medicina Molecular João Lobo Antunes
Parkinson's Disease and Parkinsonism, Glymphatic System
Effects of Exercise on Glymphatic Functioning and Neurobehavioral Correlates in Parkinson's Disease
This study is designed to measure the change in patients diagnosed with Parkinson's disease (PD) before, during and after a 12 week exercise program.The focus of this study is the glymphatic system.
- Trial name
- FIGHTPD (NCT04140708)
- Testing
- Exercise--Rock Steady Boxing class
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Vanderbilt University Medical Center
Cerebrovascular Disorders, Brain Infarction
Home-based Exercises for Patients With Stroke
The aim of this study is the development and the implementation of a new protocol about home-based exercises, supported by an illustrated manual, for the treatment of individuals with stroke.
- Conditions
- Cerebrovascular Disorders, Brain Infarction, Brain Ischemia, Stroke
- Trial name
- NCT01674452
- Testing
- home-based group (HBG), supervised exercise group (SEG)
- Where
- Brazil
- Volunteers
- 90 people
- Sponsor
- University of Sao Paulo General Hospital
Patients With Drug-resistant Focal Epilepsy, SEEG as Part of Presurgical Evaluation
Links Between Epileptic Activity, Sleep Disruption and Mental Content During Sleep
Interactions between epilepsy and sleep are numerous and bidirectional. Sleep can facilitate epileptic activity and seizures in several syndromes, while sleep deprivation increases cortical excitability and seizure…
- Trial name
- EPIDREAM 3 (NCT07605858)
- Testing
- Direct Electric Stimulation (DES)
- Where
- 2 sites in United States, France
- Volunteers
- 20 people
- Sponsor
- Hospices Civils de Lyon
Chronic Disease, Fall Patients
Nature-based Therapy Program for Parkinson's Disease (PARC)
The goal of this clinical trial is to learn if a nature-based program has positive effects on the physical and psychosocial health in a group of participants with Parkinson's disease.
- Conditions
- Chronic Disease, Fall Patients, Aging Problems, Parkinson Disease
- Trial name
- PARC (NCT06452043)
- Testing
- PARC program
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- Université du Québec à Chicoutimi
Posterior Fossa Tumor, Medulloblastoma, Childhood
Physical Activity on Postural Stability and Coordination in Children With Posterior Fossa Tumor
Medulloblastoma is a rapidly-growing tumor of the cerebellum, this area controls balance, posture and sophisticated motor functions like finer hand movements, speech, and swallowing.
- Trial name
- NCT04528316
- Testing
- Pilates Core Stability Exercises program, Balance Program, Coordination
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Children's Cancer Hospital Egypt 57357
Quality of Life
Improving Quality of Life in Nursing Home Residents: A Cluster Randomized Clinical Trial of Efficacy
Improving quality of life (QoL) in residents of nursing homes: A cluster randomized clinical trial of efficacy - The KOSMOS study.
- Trial name
- KOSMOS (NCT02238652)
- Testing
- Communication, Systematic Pain Assessment and Treatment, Medication Review
- Where
- 32 sites in Norway
- Volunteers
- 560 people
- Sponsor
- University of Bergen
Cerebral Palsy
Improved Sitting Balance: Body Functions to Participation
The aim of this study is to evaluate the changes in activity and participation domains of International Classification of Functioning, Disability and Health (ICF) in children with cerebral palsy (CP) who received integrated…
- Trial name
- NCT03788317
- Testing
- Botulinum toxin type A
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people
- Sponsor
- Kocaeli University
GHD
A Study to Investigate Efficacy and Safety of Weekly PEG-somatropin (GenSci004) in Treatment Naive Children With Growth Hormone Deficiency
The purpose of this study is to evaluate the efficacy and safety of weekly GenSci004 compared with daily Genotropin in treatment-naive children with growth failure due to GHD.
- Trial name
- ELEVATE (NCT06007417)
- Testing
- GenSci004, Genotropin
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Changchun GeneScience Pharmaceutical Co., Ltd.
Neuroinflammatory Diseases, Multiple Sclerosis
FIT-ATOMIC Exercise Feasibility Trial
This multi-center, randomized controlled feasibility trial will assess a 20-week home-based exercise intervention in youth with Multiple Sclerosis (MS).
- Trial name
- FIT-ATOMIC (NCT06870968)
- Testing
- Exercise Training, Mobility and Flexibility Training
- Where
- 4 sites in United States, Canada
- Volunteers
- 40 people
- Sponsor
- The Hospital for Sick Children
Dementia
Treatment in Occupational Therapy With Significant Activities to Improve Quality of Life
We followed a pretest-posttest non-equivalent control group experimental design study comparing two cohorts of patient with different types of dementia.
- Trial name
- NCT05359978
- Testing
- To with significance activities
- Where
- Spain
- Volunteers
- 240 people
- Sponsor
- Universidad de Burgos
Lesch-Nyhan Disease
Safety and Tolerability of the D1 Dopamine Receptor Antagonist Ecopipam in Patients With Lesch-Nyhan Disease
The purpose of this study is to determine the effects of ecopipam in patients with Lesch-Nyhan Disease (LND). Ecopipam specifically blocks the actions of one chemical in the brain that helps nerves talk to one another; ecopipam…
- Trial name
- NCT01065558
- Testing
- Ecopipam
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- Psyadon Pharma
Parkinson Disease
Zesty Exercise System for Therapeutic Engagement
This study will evaluate exercise delivered through the Zesty Exercise System for Therapeutic Engagement (ZEST-E) for people with Parkinson's disease when sessions are monitored either in person or remotely.
- Trial name
- ZEST-E (NCT07382674)
- Testing
- ZEST-E Robot-Assisted Exercise Program
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Emory University
Stroke
Lateral Perturbation Induced Step Training Compared to Lateral Voluntary Step Training in People with Chronic Stroke
The goal of this clinical trial is to see if perturbation-induced step training improves stepping performance during a reactive and voluntary step.
- Trial name
- NCT06638476
- Testing
- Perturbation Induced Step training, Voluntary step training
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Vicki Gray
Healthy Volunteers
Brain Activity Changes Measured by EEG and fMRI on Healthy Volunteers After Complex Somatosensory Stimulation
The purpose of this study is to evaluate effects on the brain after complex somatosensory stimulation with acupuncture needle. EEG and fMRI measurements will be performed.
- Trial name
- BANS (NCT01079689)
- Testing
- needle stimulation
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Dementia, Alzheimer Type
Reducing African Americans' Alzheimer's Disease Risk Through Exercise (RAATE)"
The RAATE proposal is designed to determine the effects of physical activity on risk factors for Alzheimer's Disease in older African American adults. The study will compare a physical activity program to an active control group.
- Trial name
- RAATE (NCT03890861)
- Testing
- Physical activity, Successful Aging
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Stenosis
Effects of Intense Aerobic Exercise on the Cerebrovascular Reserve Capacity in Patients With Hemodynamically Relevant Intra- and Extracranial Stenoses
The purpose of this trial is to study the improvement of cerebral hemodynamics in high risk stroke patients with impaired Cerebrovascular Reserve (CVR) due to high grade stenosis of the internal carotid (ICA) or middle cerebral…
- Trial name
- Exercise (NCT00912561)
- Testing
- Intense aerobic exercise
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Gerhard Jan Jungehuelsing
Acute Stroke, Psychomotor Agitation
Effect of Virtual Reality on Agitation in Acute Stroke
This randomized controlled, single-blind study evaluates the effect of a Virtual Reality (VR) application on agitation levels and physiological vital signs in patients with acute stroke.
- Trial name
- NCT07787910
- Testing
- Virtual Reality Application, Standard Care (in control arm)
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people
- Sponsor
- Ankara Etlik City Hospital
Dementia, Mild Cognitive Impairment
SAMi Intervention Study to Evaluate Smartwatch Interventions in Persons With MCI and Dementia
Assistive Technologies (ATs) can help people living with dementia (PwD) maintain their everyday activity. Still, there is a gap between potential and supply. Involving future users can close the gap.
- Conditions
- Dementia, Mild Cognitive Impairment, Alzheimer Disease, Dementia With Lewy Bodies
- Trial name
- SAIN_UMR (NCT05885620)
- Testing
- drinking reminder and cognitive task (smartwatch-based application)
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- University of Rostock
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